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Design of a Novel Electrochemical Aptasensor Based on Molybdenum Disulfide Nanosheets for Lysozyme Detection

Journal of Analysis and Testing 2024年第1期8卷 16-27页

作者： Tavoos Beiki Ghasem Najafpour-Darzi Maedeh Mohammadi mohsen Shakeri Biotechnology Research Laboratory Department of Chemical EngineeringBabol Noshirvani University of TechnologyBabol 47148-71167Iran Department of Mechanical Engineering Babol Noshirvani University of TechnologyBabol 47148-71167Iran

The precise detection of lysozyme plays a crucial role in early diagnosis of kidney failure in leukemia ***,we designed an electrochemical aptasensor to detect lysozyme using a glassy carbon electrode(GCE)modified with molybdenum disulfide(MoS_(2))nanosheets decorated with chitosan(Ch)and gold nanoparticles(Au).In the next steps of aptasensor preparation,aptamer(Apt)strands were immobilized on MoS_(2)-Au-Ch/GCE surface via electrostatic interactions,and bovine serum albumin(BSA)solution was applied to cover unbonded areas on Apt/MoS_(2)-Au-Ch/*** MoS_(2)-Au-Ch nanocomposite can warrant enhanced immobilization of aptamers and strong signals because of wrinkle-like structure and base planes in MoS nanosheets,presence of abundant amino and carboxyl functional groups in chitosan and Au *** pulse voltammetry(DPV)was used to evaluate the electrochemical behavior of the aptasensor at each preparation step and its detection *** developed electrochemical aptasensor based on MoS nanosheets showed remarkable performance for lysozyme detection in the range from 1 pmol/L to 10 nmol/L with a limit of detection of 2.2 fmol/*** proposed aptasensor provided excellent selectivity against BSA,uric acid,cytochrome C,lysozyme and their *** addition,it displayed great stability of about 99.58%of the initial signal upon 21-day *** on human serum and urine samples yielded promising recoveries ranging from 98 to 105%.Hence,MoS_(2)-Au-Ch nanocomposite-based aptasensor could be an outstanding candidate for medical device applications and protein quantification.

关键词： Electrochemical aptasensor Lysozyme MoS_(2)nanosheets Apt/MoS_(2)-Au-Ch/GCE

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Geyser Inspired Algorithm:A New Geological-inspired Meta-heuristic for Real-parameter and Constrained Engineering Optimization

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Journal of Bionic Engineering 2024年第1期21卷 374-408页

作者： Mojtaba Ghasemi mohsen Zare Amir Zahedi Mohammad-Amin Akbari Seyedali Mirjalili Laith Abualigah Department of Electronics and Electrical Engineering Shiraz University of TechnologyShirazIran Department of Electrical Engineering Faculty of EngineeringJahrom UniversityJahromFrasIran Department of Electrical and Computer Engineering Tarbiat Modares UniversityTehranIran Department of Electrical and Computer Engineering University ofCyprusNicosiaCyprus Centre for Artificial Intelligence Research and Optimisation Torrens University AustraliaBrisbaneQLD 4006Australia University Research and Innovation Center Obuda University1034 BudapestHungary Department of Electrical and Computer Engineering Lebanese American UniversityByblos 13-5053Lebanon Hourani Center for Applied Scientific Research Al-Ahliyya Amman UniversityAmman 19328Jordan MEU Research Unit Middle East UniversityAmman 11831Jordan Applied Science Research Center Applied Science Private UniversityAmman 11931Jordan

Over the past years,many efforts have been accomplished to achieve fast and accurate meta-heuristic algorithms to optimize a variety of real-world *** study presents a new optimization method based on an unusual geological phenomenon in nature,named Geyser inspired Algorithm(GEA).The mathematical modeling of this geological phenomenon is carried out to have a better understanding of the optimization *** efficiency and accuracy of GEA are verified using statistical examination and convergence rate comparison on numerous CEC 2005,CEC 2014,CEC 2017,and real-parameter benchmark ***,GEA has been applied to several real-parameter engineering optimization problems to evaluate its *** addition,to demonstrate the applicability and robustness of GEA,a comprehensive investigation is performed for a fair comparison with other standard optimization *** results demonstrate that GEA is noticeably prosperous in reaching the optimal solutions with a high convergence rate in comparison with other well-known nature-inspired algorithms,including ABC,BBO,PSO,and *** that the source code of the GEA is publicly available at https://***/projects/gea.

关键词： Nature-inspired algorithms Real-world and engineering optimization Mathematical modeling Geyser algorithm(GEA)

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Engineering Nano/Microscale Chiral Self‑Assembly in 3D Printed Constructs

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Nano-Micro Letters 2024年第3期16卷 313-332页

作者： mohsen Esmaeili Ehsan Akbari Kyle George Gelareh Rezvan Nader Taheri‑Qazvini Monirosadat Sadati Department of Chemical Engineering University of South CarolinaColumbiaSC 29208USA TA Instruments Waters LLCNew CastleDE 19720USA Biomedical Engineering Program University of South CarolinaColumbiaSC 29208USA

Helical hierarchy found in biomolecules like cellulose,chitin,and collagen underpins the remarkable mechanical strength and vibrant colors observed in living *** study advances the integration of helical/chiral assembly and 3D printing technology,providing precise spatial control over chiral nano/microstructures of rod-shaped colloidal nanoparticles in intricate *** designed reactive chiral inks based on cellulose nanocrystal(CNC)suspensions and acrylamide monomers,enabling the chiral assembly at nano/microscale,beyond the resolution seen in printed *** employed a range of complementary techniques including Orthogonal Superposition rheometry and in situ rheo-optic measurements under steady shear rate *** techniques help us to understand the nature of the nonlinear flow behavior of the chiral inks,and directly probe the flow-induced microstructural dynamics and phase transitions at constant shear rates,as well as their post-flow ***,we analyzed the photo-curing process to identify key parameters affecting gelation kinetics and structural integrity of the printed object within the supporting *** insights into the interplay between the chiral inks self-assembly dynamics,3D printing flow kinematics and photopolymerization kinetics provide a roadmap to direct the out-of-equilibrium arrangement of CNC particles in the 3D printed filaments,ranging from uniform nematic to 3D concentric chiral structures with controlled pitch length,as well as random orientation of chiral *** biomimetic approach can pave the way for the creation of materials with superior mechanical properties or programable photonic responses that arise from 3D nano/microstructure and can be translated into larger scale 3D printed designs.

关键词： Directed chiral self-assembly Cellulose nanocrystals Bioinspired nanocomposite 3D printing Rheology

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MV-Honeypot:Security Threat Analysis by Deploying Avatar as a Honeypot in COTS Metaverse Platforms

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Computer Modeling in Engineering & Sciences 2024年第10期141卷 655-669页

作者： Arpita Dinesh Sarang mohsen Ali Alawami Ki-Woong Park SysCore Lab.(Convergence Engineering for Intelligent Drone) Sejong UniversitySeoul05006Republic of Korea Division of Computer Engineering Hankuk University of Foreign StudiesYongin-si17035Republic of Korea Department of Information Security Sejong UniversitySeoul05006Republic of Korea

Nowadays,theuse of Avatars that are unique digital depictions has increased by users to access Metaverse—a virtual reality environment—through multiple devices and for various ***,the Avatar and Metaverse are being developed with a new theory,application,and design,necessitating the association of more personal data and devices of targeted users every *** Avatar and Metaverse technology explosion raises privacy and security concerns,leading to cyber ***-Honeypot,or Metaverse-Honeypot,as a commercial off-the-shelf solution that can counter these cyber attack-causing vulnerabilities,should be *** fill this gap,we study user’s engagements with Avatars in Metaverse,analyze possible security vulnerabilities,and create a model named Simplified Avatar Relationship Association with Non-linear Gradient(SARANG)that draws the full diagram of infrastructure components and data flow through accessing Metaverse in this *** also determine the most significant threat for each component’s cyberattacks that will affect user data and *** a result,the commercial off-the-shelf(COTS)of the MV-Honeypot must be established.

关键词： Avatar metaverse cybersecurity cloud computing internet of things artificial intelligence security analysis

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A blockchain based privacy-preserving federated learning scheme for Internet of Vehicles

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Digital Communications and Networks 2024年第1期10卷 126-134页

作者： Naiyu Wang Wenti Yang Xiaodong Wang Longfei Wu Zhitao Guan Xiaojiang Du mohsen Guizani School of Control and Computer Engineering North China Electric Power UniversityChina Department of Mathematics&Computer Science Fayetteville State UniversityFayettevilleNCUSA Department of Electrical and Computer Engineering Stevens Institute of TechnologyHobokenNJ07030USA Department of Computer Science and Engineering Qatar UniversityDohaQatar

The application of artificial intelligence technology in Internet of Vehicles(lov)has attracted great research interests with the goal of enabling smart transportation and traffic ***,concerns have been raised over the security and privacy of the tons of traffic and vehicle *** this regard,Federated Learning(FL)with privacy protection features is considered a highly promising ***,in the FL process,the server side may take advantage of its dominant role in model aggregation to steal sensitive information of users,while the client side may also upload malicious data to compromise the training of the global *** existing privacy-preserving FL schemes in IoV fail to deal with threats from both of these two sides at the same *** this paper,we propose a Blockchain based Privacy-preserving Federated Learning scheme named BPFL,which uses blockchain as the underlying distributed framework of *** improve the Multi-Krum technology and combine it with the homomorphic encryption to achieve ciphertext-level model aggregation and model filtering,which can enable the verifiability of the local models while achieving ***,we develop a reputation-based incentive mechanism to encourage users in IoV to actively participate in the federated learning and to practice *** security analysis and performance evaluations are conducted to show that the proposed scheme can meet the security requirements and improve the performance of the FL model.

关键词： Federated learning Blockchain Privacy-preservation Homomorphic encryption Internetof vehicles

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The Impact of Network Topologies and Radio Duty Cycle Mechanisms on the RPL Routing Protocol Power Consumption

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Computers, Materials & Continua 2024年第5期79卷 1835-1854页

作者： Amal Hkiri Hamzah Faraj Omar Ben Bahri Mouna Karmani Sami Alqurashi mohsen Machhout Physic Department Electronics and Micro-Electronics LaboratoryFaculty of Sciences of MonastirMonastir5000Tunisia Department of Science and Technology College of RanyahTaif UniversityP.O.Box 11099Taif21944Saudi Arabia

The Internet of Things(IoT)has witnessed a significant surge in adoption,particularly through the utilization of Wireless Sensor Networks(WSNs),which comprise small internet-connected *** deployments span various environments and offer a multitude of ***,the widespread use of battery-powered devices introduces challenges due to their limited hardware resources and communication *** response to this,the Internet Engineering Task Force(IETF)has developed the IPv6 Routing Protocol for Low-power and Lossy Networks(RPL)to address the unique requirements of such *** the critical role of RPL in maintaining high performance,this paper proposes a novel approach to optimizing power ***,it introduces a developed sensor motes topology integrated with a Radio Duty Cycling(RDC)mechanism aimed at minimizing power *** rigorous analysis,the paper evaluates the power efficiency of this approach through several simulations conducted across different network topologies,including random,linear,tree,and elliptical ***,three distinct RDC mechanisms—CXMAC,ContikiMAC,and NullRDC—are investigated to assess their impact on power *** findings of the study,based on a comprehensive and deep analysis of the simulated results,highlight the efficiency of ContikiMAC in power *** research contributes valuable insights into enhancing the energy efficiency of RPL-based IoT networks,ultimately facilitating their widespread deployment and usability in diverse environments.

关键词： WSN IoT radio duty cycles topologies

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Rosmarinic acid improves tracheal smooth muscle responsiveness and lung pathological changes in ovalbumin-sensitized rats

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Asian Pacific Journal of Tropical Biomedicine 2024年第3期14卷 100-105页

作者： Vahideh Abbasnia mohsen Foadoddini Delaram Eslimi Esfahani Mohammad Reza Khazdair Shahrbanoo Oryan Department of Biology Payame Noor UniversityTehranIran Cardiovascular Diseases Research Center Birjand University of Medical SciencesBirjandIran Department of Animal Sciences Faculty of Biological SciencesKharazmi UniversityTehranIran

Objective:To evaluate the effect of rosmarinic acid on tracheal smooth muscle responsiveness and lung pathological changes in ovalbumin-sensitized ***:Rats were randomly divided into six groups:the control group,the asthmatic group,and the asthmatic groups treated with dexamethasone(1 mg/kg;oral gavage)or three doses of rosmarinic acid(0.5,1,and 2 mg/kg;oral gavage).For induction of asthma,rats received intraperitoneal injections and inhalation of *** 21 days,bronchoalveolar lavage fluid and lung samples were collected for histopathological ***,total and differential white blood cell counts were ***:The rosmarinic acid-treated group had significantly lower tracheal smooth muscle responses to methacholine than the asthmatic *** addition,rosmarinic acid reduced white blood cell count and the percentages of eosinophils,monocytes,and neutrophils while increasing the percentage of ***-induced lung pathological changes were significantly improved by treatment with rosmarinic ***:Rosmarinic acid improves tracheal smooth muscle responsiveness and lung pathological changes in ovalbumin-sensitized rats.

关键词： Rosmarinic acid Asthma Ovalbumin Tracheal responsiveness Inflammation White blood cell

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基于变分法的四轮转向机动车辆路径规划及最优控制研究

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Acta Mechanica Sinica 2024年第2期40卷 147-161页

作者： Hami Tourajizadeh mohsen Sarvari Samira Afshari Mechanical Engineering Department Faculty of EngineeringKharazmi UniversityTehranIran University of Iowa Iowa CityIowaUSA

使用变分法对四轮转向机动车辆(4WSV)进行最优控制研究,并根据预定目标函数提取出相对最优路径.当前,4WS车辆因为其出色的操控性能增长迅速.由于4WS车辆系统是过约束的,因此车辆在两个确定边界之间可能轨迹并不唯一.由此,通过最小化预... 详细信息

使用变分法对四轮转向机动车辆(4WSV)进行最优控制研究,并根据预定目标函数提取出相对最优路径.当前,4WS车辆因为其出色的操控性能增长迅速.由于4WS车辆系统是过约束的,因此车辆在两个确定边界之间可能轨迹并不唯一.由此,通过最小化预定成本函数提取最优路径成为一项有益的研究.为了达到此目的,本文首先确定系统模型,随后应用变分法来进行车辆的最优控制.控制输入的最优值不仅满足边界条件,同时实现特定成本函数的最小化.成本函数被设定为最小化误差和能量消耗,并对相应最优路径也进行了计算.为了验证模型的正确性,本文将MATLAB的仿真结果与CarSim进行了比较.通过在MATLAB中进行解析和比较性模拟场景的分析,研究最优控制方法的效率.通过比较相应的成本函数,证明了本文提出的控制方法相较非最优策略的优越性.最后证明本文提出的最优控制方法可以获得两个预定边界之间的最优路径,并通过该使用变分法对四轮转向机动车辆(4WSV)进行最优控制研究,并根据预定目标函数提取出相对最优路径.当前,4WS车辆因为其出色的操控性能增长迅速.由于4WS车辆系统是过约束的,因此车辆在两个确定边界之间可能轨迹并不唯一.由此,通过最小化预定成本函数提取最优路径成为一项有益的研究.为了达到此目的,本文首先确定系统模型,随后应用变分法来进行车辆的最优控制.控制输入的最优值不仅满足边界条件,同时实现特定成本函数的最小化.成本函数被设定为最小化误差和能量消耗,并对相应最优路径也进行了计算.为了验证模型的正确性,本文将MATLAB的仿真结果与CarSim进行了比较.通过在MATLAB中进行解析和比较性模拟场景的分析,研究最优控制方法的效率.通过比较相应的成本函数,证明了本文提出的控制方法相较非最优策略的优越性.最后证明本文提出的最优控制方法可以获得两个预定边界之间的最优路径,并通过该路径可以实现最大准确性和最小能量消耗.

关键词：成本函数最优控制机动车辆变分法能量消耗四轮转向车辆路径规划最优路径

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RPL-Based IoT Networks under Decreased Rank Attack:Performance Analysis in Static and Mobile Environments

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Computers, Materials & Continua 2024年第1期78卷 227-247页

作者： Amal Hkiri Mouna Karmani Omar Ben Bahri Ahmed Mohammed Murayr Fawaz Hassan Alasmari mohsen Machhout Physic Department Electronics and Micro-Electronics LaboratoryFaculty of Sciences of MonastirMonastir5000Tunisia Department of Science and Technology College of RanyahTaif UniversityP.O.Box 11099Taif21944Saudi Arabia

The RPL(IPv6 Routing Protocol for Low-Power and Lossy Networks)protocol is essential for efficient communi-cation within the Internet of Things(IoT)*** its significance,RPL’s susceptibility to attacks remains a *** paper presents a comprehensive simulation-based analysis of the RPL protocol’s vulnerability to the decreased rank attack in both static andmobilenetwork *** employ the Random Direction Mobility Model(RDM)for mobile scenarios within the Cooja *** systematic evaluation focuses on critical performance metrics,including Packet Delivery Ratio(PDR),Average End to End Delay(AE2ED),throughput,Expected Transmission Count(ETX),and Average Power Consumption(APC).Our findings illuminate the disruptive impact of this attack on the routing hierarchy,resulting in decreased PDR and throughput,increased AE2ED,ETX,and *** results underscore the urgent need for robust security measures to protect RPL-based IoT ***,our study emphasizes the exacerbated impact of the attack in mobile scenarios,highlighting the evolving security requirements of IoT networks.

关键词： RPL decreased rank attacks mobility random direction model

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Evaluation of Mechanical Properties and Surface Quality of Wood from Bosnia and Herzegovina Exposed to Outdoor Conditions

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Journal of Renewable Materials 2024年第8期12卷 1417-1431页

作者： Redžo Hasanagić UmejrŠljivo Leila Fathi Pallavi Gautam mohsen Bahmani Miha Humar Department of Wood Science and Technology Faculty of Technical EngineeringUniversity of BihaćBihać77000Bosnia and Herzegovina Department of Wood and Furniture Industry Engineering Faculty of Resources and Earth ScienceShahrekord UniversityShahrekord64165478Iran Department of Botany Institute of ScienceBanaras Hindu UniversityVaranasiUttar Pradesh221005India Biotechnical Faculty Department of Wood ScienceUniversity of LjubljanaLjubljana1501Slovenia

This study investigated the mechanical properties of beech(Fagus sylvatica L.)and fir(Abies alba)wood from Bosnia and Herzegovina under outdoor *** were exposed for 3-month exposure to assess bending strength,color changes,and surface *** showed outdoor exposure negatively affected mechanical properties,particularly in samples with extended finger joints,causing significant surface cracks in uncoated *** wood exhibited notable color changes under exposure,with approximately 50%darkening without coating compared to 25%under covered *** samples displayed minimal color changes,affirming the efficacy of surface *** wood exhibited a roughness of 8.264μm,while beechwood average roughness increased from 6.767 to 13.916μm after exposure,with micro-pore development affecting water *** analysis identified prevalent fungal colonies,including Penicillium,Aureobasidium,Sclerophoma,and Chaetomium,underscoring their role in organic matter *** study highlights the importance of wood exposure and treatment selection for various applications.

关键词： Mechanical properties outdoor conditions cracks wood species

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