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Inflammatory bowel disease incidence in Czech children:A regional prospective study,2000-2015

World Journal of Gastroenterology 2017年第22期23卷 4090-4101页

作者： Jan Schwarz Josef Sykora Dominika Cvalínová Renáta Pomahacová Jana Klecková Martin Kryl Petr Vcelák Department of Paediatrics Charles UniversityFaculty of Medicine in PilsenFaculty Hospital Department of Computer Science and NTIS-Research Centre Faculty of Applied SciencesUniversity of West Bohemia

AIM To examine the incidence and trends in pediatric inflammatory bowel diseases(IBDs) over 2000-2015 and project the incidence to 2018. METHODS A 16-year prospective study of IBD patients ucted in the Czech Republic(the Pilsen region). All incident IBD cases within a well-defined geographical area were retrieved from a prospectively collected computerized clinical database. Historical Czech data were used for comparison(1990-2001). Our catchment population was determined from the census data. We calculated the incidence by relating the number of newly diagnosed cases to the size of thepediatric population-at-risk in each calendar year. Age/sex, disease type, place of residence, and race/ethnicity were identified. RESuLTS In total, 170 new IBD cases [105 Crohn's disease(CD), 48 ulcerative colitis(uC), and 17 IBD-unclassified(IBD-u)] were identified. The median age at IBD diagnosis was 14.2 years, 59.4% were males, and 97.1% were Caucasians. A male preponderance of IBD(P = 0.026) and CD(P = 0.016) was observed. With 109209 person-years in the catchment area, the average incidence of IBD per 100000 person-years was 10.0(6.2 for CD, 2.8 for uC, and 1.0 for IBD-u) for children aged 0 to 19 years; for those aged 0 to 15 years, the incidence rate was 7.3(4.6 for CD, 2.0 for uC, and 0.7 for IBD-u). An increase in incidence with age was observed(P = 0.0003). Over the 16-year period, the incidence increased for IBD patients(P = 0.01) and CD in particular(P uC(P = 0.09) and IBD-u(P = 0.339) remained unchanged. IBD-projected data from 2016 to 2018 were 12.1, 12.3 and 12.6 per 100000 personyears, *** Pediatric-onset IBD incidence is around its highest point. The increase, which is particularly pronounced for CD, may be challenging to relate to causes of pediatric disease.

关键词： Inflammatory bowel disease Incidence Children Czech Republic Pilsen region Projections Crohn’s disease ulcerative colitis

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Premier Wen Meets with Delegation of u.S. Aspen Institute

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Voice of Friendship 2005年第4期 4-6,33页

作者： ba Cuicui

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uS Georgetown university President John DeGioia Leads Delegation to China

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Voice of Friendship 2009年第4期 17-18页

作者： ba Cuicui

Invited by the CPAFFC, John J. DeGioia, president of Georgetown university of the u. S.,and his party visited Gansu, Jiangxi and Hubei provinces and Beijing from March 4 to 9. Liu Yandong, state councillor; Li Yuancha... 详细信息

关键词： visited Jiangxi party Hubei president delegation c

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RECENT LABORATORY INVESTIGATIONS BY CHINESE WORKERS ON ANTISCHISTOSOMAL ACTIVITIES OF PRAZIQuANTEL

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中华医学杂志(英文版) 1991年第7期104卷 599-606页

作者：肖树华符遂 Catto ba Institute of Parasitic Diseases Chinese Academy of Preventive Medicine WHO Collaboratintg Centre for Malaria Schistosomiasis and Filariasis Shanghai 200025 Section of Infectious Diseases Deparment of Medicine Medical College of Georagia Augusta Georgia 30912 u.S.A

Praziquantel (PZQ), a widely-used antis- chistosomal drug, has stimulated a number of laboratory and clinical investigations in China, results of which are not widely disseminated in English. Recent investigations on the effect of PZQ against Schistosoma jap onicum were reviewed hereby in order to exchange academic ideas and promote further researches on antischistosomal drugs.

关键词： SCHISTOSOMA-JAPONICuM CERCARIAE DIFFERENT DEVELOPMENtaL StaGES INVITRO NEuTROPHILS MANSONI SuRFACE RABBITS

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Salt effect on molecular orientation at air/liquid methanol interface

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Chinese Chemical Letters 2016年第4期27卷 535-539页

作者： Xia Li Gang-Hua Deng Rong-Juan Feng Ke Lin Zhen Zhang Yu ba Zhou Lu Yuan Guo Beijing National Laboratory for Molecular Sciences State Key Laboratory of Molecular Reaction Dynamics Institute of Chemistry Chinese Academy of Sciences Hefei National Laboratory for Physical Sciences at the Microscale University of Science and Technology of China School of Physics and Optoelectronic Engineering Xidian University

The salt effects on molecular orientation at air/liquid methanol interface were investigated by the polarization-dependent sum frequency generation vibrational spectroscopy（SFG-VS）. We clarified that the average tilting angle of the methyl group to be u = 308 58 at the air/pure methanol surface assuming a d-function orientational distribution. upon the addition of 3 mol/L Na I, the methyl group tilts further away from the surface normal with a new u = 418 38. This orientational change does not explain the enhancement of the SFG-VS intensities when adding Na I, implying the number density of the methanol molecules with a net polar ordering in the surface region also changed with the Na I concentrations. These spectroscopic findings shed new light on the salt effects on the surfaces structures of the polar organic solutions. It was also shown that the accurate determination of the bulk refractive indices and Raman depolarization ratios for different salt concentrations is crucial to quantitatively interpret the SFG-VS data.

关键词： Surface orientation Air/liquid interface Salt effect Sum frequency generation Methanol

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海洋潮差区混凝土表面微生物16S rDNA分子鉴定

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哈尔滨工程大学学报 2010年第10期31卷 1386-1392页

作者：吕建福李杰莫照兰巴恒静哈尔滨工业大学交通科学与工程学院黑龙江哈尔滨150090 哈尔滨工业大学土木工程学院黑龙江哈尔滨150090 中国科学院海洋研究所山东青岛266071

针对目前海洋混凝土工程的腐蚀现状,进行了海洋微生物对潮差区混凝土的作用机理及完善海工混凝土的腐蚀机理探索.通过海工混凝土潮差区部位取样,对暴露于潮差区中部22 y的混凝土试样表面进行FE-SEM、EDAX分析,结果表明:潮差区混凝土表... 详细信息

针对目前海洋混凝土工程的腐蚀现状,进行了海洋微生物对潮差区混凝土的作用机理及完善海工混凝土的腐蚀机理探索.通过海工混凝土潮差区部位取样,对暴露于潮差区中部22 y的混凝土试样表面进行FE-SEM、EDAX分析,结果表明:潮差区混凝土表面腐蚀严重,结构疏松,表面覆盖有有机物质和微生物.并将暴露于潮差区中部22 y的混凝土试样和该取样位置挂置7 d的混凝土试样表面的微生物群落分别分离,克隆了其中30株和12株细菌的16S rDNA基因,测定其序列且进行比对,其分别属于15个和7个种属中.优势种属均为假交替单胞菌,但随着暴露时间的增加,总细菌株数和总菌属数分别增大到2.5和2.14倍,且种属的变化也很大.同时,建立了海洋混凝土工程表面细菌鉴定方法,以及分离、鉴定的菌种为后续细菌对混凝土作用的试验提供菌种.

关键词：海洋微生物 16S rDNA 海洋混凝土工程分子鉴定

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Graphene-coated copper foam interlayer for brazing carbon/carbon composite and niobium

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China Welding 2019年第4期28卷 33-38页

作者： Wang Zeyu ba Jin Qi Junlei Feng Jicai State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001China

Problems such as poor structural integrity,inhomogeneous dispersion,and agglomeration of graphene in the brazing seam are typically encountered for graphene additives in a brazed joint *** resolve these problems,a plasma-enhanced chemical vapor deposition process was employed for in-situ preparation of a high-quality graphene-coated copper(Cu)foam composite interlayer prior to be applied for brazing carbon/carbon composite and *** prepared graphene and the brazed joints were characterized via Raman spectroscopy,scanning electron microscopy,and high-resolution transmission electron *** results revealed that graphene was evenly distributed in the brazing seam with the help of the Cu foam,which was characterized by interconnected ***,the excellent chemical inertia of graphene inhibited the collapse of the Cu foam,based on which the thermal residual stress in the joint was effectively mitigated due to the synergistic reinforcement effect of the Cu foam(with good plastic deformation capacity)and graphene(with extremely low coefficient of linear expansion).This effect led to significant improvement in the average shear strength of the joint.

关键词： graphene composite interlayer brazing carbon/carbon composite residual stress

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A TWO-PHASE APPROACH TO FuZZY SYSTEM IDENTIFICATION

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Systems Science and Systems Engineering 2003年第4期12卷 408-423页

作者： ta-Wei HuNG Shu-Cherng FANG Henry L.W.NuTTLE Department of Information Management Shih Chien university Taipei Taiwan 10497 ChinaGraduate Program in Operations Research and Department of Industrial Engineering North Carolina State University Raleigh NC 27695-7906 U.S.A.Graduate Program in Operations Research and Department of Industrial Engineering North Carolina State University Raleigh NC 27695-7906 U.S.A.

A two-phase approach to fuzzy system identification is proposed. The first phase produces a baseline design to identify a prototype fuzzy system for a.ta.get system from a collection of input-output data pairs. It uses two easily implemented clustering techniques: the subtractive clustering method and the fuzzy c-means (FCM) clustering algorithm. The second phase (fine tuning) is executed to adjust the parameters identified in the baseline design. This phase uses the steepest descent and recursive least-squares estimation methods. The proposed approach is validated by applying it to both a function approximation type of problem and a classification type of problem. An analysis of the learning behavior of the proposed approach for the two test problems is conducted for further confirmation.

关键词： Fuzzy inference systems fuzzy system models fuzzy clustering learning

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Effect of harvest time on the chemical composition and antioxidant capacity of Gannan navel orange(Citrus sinensis L. Osbeck 'Newhall')juice

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Journal of Integrative Agriculture 2022年第1期21卷 261-272页

作者： ZHANG Jun ZHANG Jing-yi SHAN You-xia GuO Can HE Lian ZHANG Lin-yan LING Wei LIANG Yan ZHONG ba-lian National Engineering Research Center of Navel Orange Gannan Normal UniversityGanzhou 341000P.R.China South China Botanical Garden Chinese Academy of SciencesGuangzhou 510650P.R.China

The present study investigates the chemical composition and antioxidant capacity of juice from the Gannan navel orange, which is harvested at one-to two-week intervals during the ripening period. The total soluble solid(TSS), total polyphenol content(TPC), total flavonoid content(TFC), sucrose and hesperidin contents gra.ually increase with the ripening of the fruit, followed by slight declines at the late ma.urity stage. Contrary to these observations, the contents of titratable acid(ta), vitamin C(Vc), and limonin trend downward throughout the ripening period. However, the contents of fructose, glucose, and narirutin fluctuate throughout the harvest time. Three in vitro antioxidant assays consistently indicate that the harvest time exerts no significant influence(P>0.01) on the antioxidant capacity. Furthermore, principal component analysis(PCA) and Pearson’s correlation test are performed to provide an overview of the complete *** study provides va.uable information for eva.uating the fruit quality and determining when to harvest the fruit in order to meet the preferences of consumers. Meanwhile, our observations suggest that the fruits subjected to juice processing should be harvested at the late ma.urity stage to alleviate the "delayed bitterness" problem without compromising the antioxidant capacity and the flavonoid content in the juice.

关键词： navel orange antioxidant harvest time chemical composition

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大体积混凝土温度实测与芯部的力学性能发展规律

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建筑技术 2006年第6期37卷 439-440页

作者：吕常新吕建福巴恒静杭州市交通设施建设处杭州310005 哈尔滨工业大学土木工程学院哈尔滨150006

通过对千岛湖一号特大桥拱座大体积混凝土的温度实测,得到混凝土温度场数据。根据实测的温度发展规律,在实验室内进行温度匹配养护,测试混凝土的力学性能。实验结果表明,匹配养护的混凝土的强度较标养下早期发展速度快很多,匹配养护的... 详细信息

通过对千岛湖一号特大桥拱座大体积混凝土的温度实测,得到混凝土温度场数据。根据实测的温度发展规律,在实验室内进行温度匹配养护,测试混凝土的力学性能。实验结果表明,匹配养护的混凝土的强度较标养下早期发展速度快很多,匹配养护的混凝土后期强度趋势发展平缓;弹性模量与强度的发展规律相似。

关键词：大体积混凝土温度发展规律匹配养护

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