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Estimation of Sex by Applying Discriminant Function Analysis on Osteo-metric Parameters of Clavicle in Population of Haryana

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Journal of Forensic Science and Medicine 2023年第2期9卷 106-111页

作者： Arun Kumar Luv Sharma Archana Gaurav Kaushik Naresh Saini Ravi Kanth Soni mohan singh meena Department of Forensic Medicine National Institute of Medical Sciences and ResearchNIMS UniversityJaipurRajasthanIndia Department of Forensic Medicine PGIMSRohtakHaryanaIndia Department of Organaon of Medicine Sri Ganganagar Homeopathic Medical CollegeSri GanganagarRajasthanIndia

It is important to pinpoint the identity of the deceased in scenarios such as decomposed bodies,skeletonized remains,mutilated remains,exhumed dead bodies,and in mass *** are many important parameters to establish the identity of a *** estimation of sex is one of *** of sex from bones is easy when the whole skeleton is available,but it becomes difficult when the body is mutilated and only parts of the body or bones are *** present study is undertaken to estimate the sex by applying discriminant function analysis(DFA)on various osteo-metric parameters of the clavicle in the population of *** hundred pairs of clavicles were collected from the bodies brought for *** were macerated and air dried for the removal of soft *** variables of clavicle of both sexes were measured and analyzed using the analysis of variance test which provided descriptive *** of the values helped in sexing of the *** of sex from different parameters of the clavicle was possible with overall accuracy of 93%in original and 92.5%in crossvalidated cases among total *** was 96%and 90%in original and 96%and 89%in cross validated cases among males and females respectively,indicating a strong correlation in estimation of sex of a person from the *** most important parameters to determine the sex from the clavicle are length of clavicle,mid clavicular circumference of clavicle,weight of clavicle,transverse diameter of lateral end of right clavicle,and longitudinal diameter of medial end of the left clavicle.

关键词： Clavicle estimation of sex identification

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Photonic properties and applications of multi-functional organo-lanthanide complexes:Recent advances

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Journal of Rare Earths 2024年第1期42卷 16-27,I0001页

作者： Virender Archana Chauhan Ashwani Kumar Gurjaspreet singh Alexander A.Solovev Jichuan Xiong Xuefeng Liu Brij mohan Department of Chemistry Kurukshetra University KurukshetraKurukshetra136119India Aggarwal College Ballabhgarh121004Department of Higher EducationHaryanaIndia Department of Chemistry&Centre for Advanced Studies in Chemistry Panjab UniversityChandigarh160014India Department of Materials Science Fudan UniversityShanghai200433China School of Electronic and Optical Engineering Nanjing University of Science and TechnologyNanjing210094China College of Ocean Food and Biological Engineering Jimei UniversityXiamen361021China

Lanthanides(Ln(Ⅲ))based compounds as light-emitting materials have emerged as successful agents in high-performance defense and lighting systems,magnets,bio-markers,and ***,they have recently gained much attention as energy-saving and cost-effective luminescent materials and their applications in analyte *** present review summarizes powerful features and recent developments of organo-lanthanide complexes in lighting applications with a particular focus on visible light emitters,including Eu(Ⅲ),Tb(Ⅲ),Sm(Ⅲ),and Dy(Ⅲ)*** addition,this review discusses the most relevant aspects of photosensitization,such as the structure,property,functionalization of primary and secondary ligands,and molecular *** addition,coordination sites of organo-lanthanide complexes and their applications collectively contribute to the improved performance of innovative luminescent ***,the current challenges and key recommendations for advancing organolanthanides in material science are provided.

关键词： Lanthanides Organometallic Luminescent Lifetime OLED Rare earths

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Outcome of patients with traumatic cranial nerve palsy admitted to a university hospital in Nepal

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中华神经外科杂志(英文) 2024年第2期10卷 1-7页

作者： Kumari Khusbu Gautam Naveen Parajuli Monika singh Shreejana Pradhananga Amit Sedai Gopal Shilpakar Sushil Sharma mohan Raj Maharajgunj Medical Campus Institute of Medicine Tribhuvan University Maharajgunj Kathmandu Nepal Department of Research Institute of Medicine Maharajgunj Kathmandu Nepal Department of Neurosurgery Tribhuvan University Teaching Hospital Maharajgunj Kathmandu Nepal

Background Cranial nerve palsy (CNP) is a common complication of traumatic brain injury (TBI). Despite a high incidence of TBI in Nepal (382 per 100,000), literature on the specific management and outcome of CNP is lacking. This study aimed to examine the outcomes of TBI patients involving single versus multiple *** A retrospective chart review of 170 consecutive TBI patients admitted to the tertiary neurosurgical center in Nepal between April 2020 and April 2022 was conducted. Demographic, clinical, and etiological characteristics; imaging findings; and management strategies were recorded, compared, and analyzed using descriptive statistics. The Glasgow Outcome Scale Extended (GOSE) was used to measure the outcomes in two groups of patients (single and multiple CNP) at 3 *** Out of 250 eligible patients, 80 were excluded and CNP was noted in 29 (17.1%) of the remaining 170. The median age was 34.9 years, and falls (60.6%) were the most common cause of trauma. TBI severity was categorized based on GCS: mild (82.4%), moderate (15.9%), and severe (1.8%). Cranial nerve involvement was seen in 29 (17.05%) patients: single cranial nerve involvement in 26 (89.65%) and multiple nerve involvement in 3 (10.34%). The most common isolated cranial nerve involved was the oculomotor nerve (37.9%). CT findings revealed a maximum of skull fractures with no significant association between CNP and CT *** CNP is a common consequence of TBI with the most common etiology being falls followed by RTA. Single CNP was more common than multiple CNP with no significant difference in the outcome in the 3-month GOSE score. Further research is needed to determine the burden of traumatic CNP and establish specific management guidelines for different types of CNP.

关键词： Cranial nerve palsy Nepal Outcome Traumatic brain injury

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Role of fecal microbiota transplant in management of hepatic encephalopathy: Current trends and future directions

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World Journal of Hepatology 2024年第1期16卷 17-32页

作者： Yash R Shah Hassam Ali Angad Tiwari David Guevara-Lazo Natalia Nombera-Aznaran Bhanu Siva mohan Pinnam Manesh Kumar Gangwani Harishankar Gopakumar Amir H Sohail SriLakshmiDevi Kanumilli Ernesto Calderon-Martinez Geetha Krishnamoorthy Nimish Thakral Dushyant singh Dahiya Department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States Division of Gastroenterology and Hepatology East Carolina University/Brody School of MedicineGreenvilleNC 27858United States Department of Internal Medicine Maharani Laxmi Bai Medical CollegeJhansi 284001India Faculty of Medicine Universidad Peruana Cayetano HerediaLima 15102Peru Department of Internal Medicine John H.Stroger Hospital of Cook CountyChicagoIL 60612United States Department of Internal Medicine The University of ToledoToledoOH 43606United States Department of Gastroenterology and Hepatology University of Illinois College of Medicine at PeoriaPeoriaIL 61605United States Department of Surgery University of New MexicoAlbuquerqueNM 87106United States Department of Internal Medicine GSL Medical CollegeRajamahendravaram 533296India Department of Internal Medicine Universidad Nacional Autonoma de MexicoCiudad De Mexico 04510Mexico Department of Digestive Diseases and Nutrition University of KentuckyLexingtonKY 40536United States Division of Gastroenterology Hepatology&MotilityThe University of Kansas School of MedicineKansas CityKS 66160United States

Fecal microbiota transplantation(FMT)offers a potential treatment avenue for hepatic encephalopathy(HE)by leveraging beneficial bacterial displacement to restore a balanced gut *** prevalence of HE varies with liver disease severity and *** pathogenesis involves ammonia toxicity,gut-brain communication disruption,and *** aims to restore gut microbiota balance,addressing these ***'s efficacy has been explored in various conditions,including *** suggest that FMT can modulate gut microbiota,reduce ammonia levels,and alleviate *** has shown promise in alcohol-associated,hepatitis B and C-associated,and non-alcoholic fatty liver *** include improved liver function,cognitive function,and the slowing of disease ***,larger,controlled studies are needed to validate its effectiveness in these *** have shown cognitive improvements through FMT,with potential benefits in cirrhotic ***,trials have demonstrated reduced serious adverse events and cognitive enhancements in FMT arms compared to the standard of *** evidence is promising,challenges remain:Limited patient numbers,varied dosages,administration routes,and donor *** large-scale,controlled trials are essential to establish standardized guidelines and ensure FMT's clinical applications and *** FMT holds potential for HE management,ongoing research is needed to address these challenges,optimize protocols,and expand its availability as a therapeutic option for diverse hepatic conditions.

关键词： Hepatic encephalopathy Fecal microbiota transplant Cognitive impairment Liver cirrhosis Chronic liver disease

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Association between acute peripancreatic fluid collections and early readmission in acute pancreatitis:A propensity-matched analysis

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World Journal of Experimental Medicine 2024年第2期14卷 75-88页

作者： Hassam Ali Faisal Inayat Waqas Rasheed Arslan Afzal Ahtshamullah Chaudhry Pratik Patel Attiq Ur Rehman Muhammad Sajeel Anwar Gul Nawaz Muhammad Sohaib Afzal Amir H Sohail Subanandhini Subramanium Dushyant singh Dahiya Deepa Budh Babu P mohan Douglas G Adler Department of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Department of Internal Medicine Texas Tech University Health Sciences CenterLubbockTX 79430United States Department of Internal Medicine St.Dominic’s HospitalJacksonMS 39216United States Department of Gastroenterology Mather Hospital and Hofstra University Zucker School of MedicinePort JeffersonNY 11777United States Department of Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Department of Internal Medicine Louisiana State University HealthShreveportLA 71103United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Division of Gastroenterology Hepatologyand MotilityThe University of Kansas School of MedicineKansas CityKS 64108United States Department of Internal Medicine St.Barnabas Hospital and Albert Einstein College of MedicineBronxNY 10457United States Department of Gastroenterology and Hepatology University of Utah School of MedicineSalt Lake CityUT 84132United States Center for Advanced Therapeutic Endoscopy Porter Adventist HospitalCentura HealthDenverCO 80210United States

BACKGROUND Patients with acute pancreatitis(AP)frequently experience hospital readmissions,posing a significant burden to healthcare *** peripancreatic fluid collection(APFC)may negatively impact the clinical course of *** could worsen symptoms and potentially lead to additional ***,clinical evidence regarding the specific association between APFC and early readmission in AP remains *** the link between APFC and readmission may help improve clinical care for AP patients and reduce healthcare *** To evaluate the association between APFC and 30-day readmission in patients with *** This retrospective cohort study is based on the Nationwide Readmission Database for *** with a primary diagnosis of AP were *** were categorized into those with and without APFC.A 1:1 propensity score matching for age,gender,and Elixhauser comorbidities was *** primary outcome was early readmission *** outcomes included the incidence of inpatient complications and healthcare *** analyses used Mann-Whitney U andχ2 tests,while Cox regression models assessed 30-day readmission risks and reported them as adjusted hazard ratios(aHR).Kaplan-Meier curves and log-rank tests verified readmission *** A total of 673059 patients with the principal diagnosis of AP were *** these,5.1%had APFC on initial *** propensity score matching,each cohort consisted of 33914 *** with APFC showed a higher incidence of inpatient complications,including septic shock(3.1%vs 1.3%,P<0.001),portal venous thrombosis(4.4%vs 0.8%,P<0.001),and mechanical ventilation(1.8%vs 0.9%,P<0.001).The length of stay(LOS)was longer for APFC patients[4(3-7)vs 3(2-5)days,P<0.001],as were hospital charges($29451 vs$24418,P<0.001).For 30-day readmissions,APFC patients had a higher rate(15.7%vs 6.5%,P<0.001)and a longer median readmission LOS(4 vs 3 days,P<0.001).The APF

关键词： Acute pancreatitis Acute peripancreatic fluid collections Readmission predictors Inpatient complications Healthcare utilization and costs

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MCBC-SMOTE:A Majority Clustering Model for Classification of Imbalanced Data

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Computers, Materials & Continua 2022年第12期73卷 4801-4817页

作者： Jyoti Arora meena Tushir Keshav Sharma Lalit mohan Aman singh Abdullah Alharbi Wael Alosaimi Department of Information Technology MSITGGSIPUNew Delhi110058India Department of Electrical and Electronic Engineering MSITGGSIPUNew Delhi110058India School of Computer Science and Engineering Lovely Professional University144411PunjabIndia Department of Information Technology College of Computers and Information TechnologyTaif University11099Taif 21944Saudi Arabia

Datasets with the imbalanced class distribution are difficult to handle with the standard classification *** supervised learning,dealing with the problem of class imbalance is still considered to be a challenging research *** machine learning techniques are designed to operate on balanced datasets;therefore,the state of the art,different undersampling,over-sampling and hybrid strategies have been proposed to deal with the problem of imbalanced datasets,but highly skewed datasets still pose the problem of generalization and noise generation during *** overcome these problems,this paper proposes amajority clusteringmodel for classification of imbalanced datasets known as MCBC-SMOTE(Majority Clustering for balanced Classification-SMOTE).The model provides a method to convert the problem of binary classification into a multi-class *** the proposed algorithm,the number of clusters for themajority class is calculated using the elbow method and the minority class is over-sampled as an average of clustered majority classes to generate a symmetrical class *** proposed technique is cost-effective,reduces the problem of noise generation and successfully disables the imbalances present in between and within *** results of the evaluations on diverse real datasets proved to provide better classification results as compared to state of the art existing methodologies based on several performance metrics.

关键词： Imbalance class problem classification SMOTE k-means clustering sampling

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Impact of frailty on endoscopic retrograde cholangiopancreatography outcomes in nonagenarians:A United States national experience

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World Journal of Gastrointestinal Endoscopy 2024年第3期16卷 148-156页

作者： Sanket Dhirubhai Basida Dushyant singh Dahiya Muhammad Nadeem Yousaf Brinda Basida Bhanu Siva mohan Pinnam Manesh Kumar Gangwani Hassam Ali Sahib singh Yash R Shah Daksh Ahluwalia Mihir Prakash Shah Saurabh Chandan Neil R Sharma Shyam Thakkar Department of Internal Medicine University of Missouri-ColumbiaColumbiaMO 65212United States Division of Gastroenterology Hepatology&MotilityThe University of Kansas School of MedicineKansas CityKS 66160United States Division of Gastroenterology and Hepatology University of MissouriColumbiaMO 65212United States Department of Rheumatology Medical College of GeorgiaAugusta UniversityNorth AugustaGA 30912United States Department of Internal Medicine John H.Stroger Hospital of Cook CountyChicagoIL 60612United States Department of Internal Medicine The University of ToledoToledoOH 43606United States Division of Gastroenterology and Hepatology East Carolina University/Brody School of MedicineGreenvilleNC 27858United States Department of Internal Medicine Sinai HospitalBaltimoreMD 21215United States Department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States Division of Gastroenterology and Hepatology Creighton University School of MedicineOmahaNE 68131United States Division of Interventional Oncology&Surgical Endoscopy GI Oncology Tumor Site TeamParkview Cancer InstituteParkview HealthFort WayneIN 46845United States Section of Gastroenterology&Hepatology West Virginia University School of MedicineMorgantownWV 26505United States

BACKGROUND Endoscopic retrograde cholangiopancreatography(ERCP)is an essential therapeutic tool for biliary and pancreatic *** and elderly patients,especially those aged≥90 years are generally considered a higher-risk population for ERCP-related *** To investigate outcomes of ERCP in the Non-agenarian population(≥90 years)concerning *** This is a cohort study using the 2018-2020 National Readmission *** aged≥90 were identified who underwent ERCP,using the international classification of diseases-10 code with clinical *** Hopkins’s adjusted clinical groups frailty indicator was used to classify patients as frail and *** primary outcome was mortality,and the secondary outcomes were morbidity and the 30 d readmission rate related to *** used univariate and multivariate regression models for *** A total of 9448 patients were admitted for any indications of *** and non-frail patients were 3445(36.46%)and 6003(63.53%)*** for ERCP were Choledocholithiasis(74.84%),Biliary pancreatitis(9.19%),Pancreatico-biliary cancer(7.6%),Biliary stricture(4.84%),and Cholangitis(1.51%).Mortality rates were higher in frail group[adjusted odds ratio(aOR)=1.68,P=0.02].The Intra-procedural complications were insigni-ficant between the two groups which included bleeding(aOR=0.72,P=0.67),accidental punctures/lacerations(aOR=0.77,P=0.5),and mechanical ventilation rates(aOR=1.19,P=0.6).Post-ERCP complication rate was similar for bleeding(aOR=0.72,P=0.41)and post-ERCP pancreatitis(aOR=1.4,P=0.44).Frail patients had a longer length of stay(6.7 d vs 5.5 d)and higher mean total charges of hospitalization($78807 vs$71392)compared to controls(P<0.001).The 30 d all-cause readmission rates between frail and non-frail patients were similar(P=0.96).CONCLUSION There was a significantly higher mortality risk and healthcare burden amongst nonagenarian frail patients undergoing ERCP compared

关键词： Endoscopic retrograde cholangiopancreatography Nonagenarians Frailty Mortality Healthcare burden

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Remimazolam for sedation in gastrointestinal endoscopy:A comprehensive review

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World Journal of Gastrointestinal Endoscopy 2024年第7期16卷 385-395页

作者： Dushyant singh Dahiya Ganesh Kumar Syeda Parsa Manesh Kumar Gangwani Hassam Ali Amir Humza Sohail Saqr Alsakarneh Umar Hayat Sheza Malik Yash R Shah Bhanu Siva mohan Pinnam Sahib singh Islam Mohamed Adishwar Rao Saurabh Chandan Mohammad Al-Haddad Division of Gastroenterology Hepatology&MotilityThe University of Kansas School of MedicineKansas CityMO 66160United States Department of Internal Medicine Chandka Medical CollegeSindh 77280Pakistan Department of Gastroenterology and Hepatology University of Arkansas For Medical SciencesLittle RockAR 72205United States Division of Gastroenterology Hepatology and NutritionEast Carolina University/Brody School of MedicineGreenvilleNC 27858United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Department of Internal Medicine University of Missouri-Kansas CityKansas CityMO 64108United States Department of Internal Medicine Geisinger Wyoming Valley Medical CenterWilkes BarrePA 18711United States Department of Internal Medicine Rochester General HospitalRochesterNY 14621United States Department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States Department of Internal Medicine John H.Stroger Hospital of Cook CountyChicagoIL 60612United States Department of Internal Medicine Sinai hospitalBaltimoreMD 21215United States Department of Hepatology University of MissouriColumbiaMO 65211United States Department of Internal Medicine Guthrie Robert Packer HospitalSayrePA 18840United States Division of Gastroenterology and Hepatology Creighton University School of MedicineOmahaNE 68131United States Division of Gastroenterology and Hepatology Indiana University School of MedicineIndianapolisIN 46202United States

Worldwide,a majority of routine endoscopic procedures are performed under some form of sedation to maximize patient ***,benzodiazepines and opioids continue to be widely ***,in recent years,Remimazolam is gaining immense popularity for procedural sedation in gastrointestinal(GI)*** is an ultra-short-acting benzodiazepine sedative which was approved by the Food and Drug Administration in July 2020 for use in procedural *** has shown a favorable pharmacokinetic and pharmacodynamic profile in terms of its non-specific metabolism by tissue esterase,volume of distribution,total body clearance,and negligible drug-drug *** also has satisfactory efficacy and has achieved high rates of successful sedation in GI ***,studies have demonstrated that the efficacy of Remimazolam is non-inferior to Propofol,which is currently a gold standard for procedural sedation in most parts of the ***,the use of Propofol is associated with hemodynamic instability and respiratory *** contrast,Remimazolam has lower incidence of these adverse effects intra-procedurally and hence,may provide a safer alternative to Propofol in procedural *** this comprehensive narrative review,highlight the pharmacologic characteristics,efficacy,and safety of Remimazolam for procedural *** also discuss the potential of Remimazolam as a suitable alternative and how it can shape the future of procedural sedation in gastroenterology.

关键词： Remimazolam Endoscopy Sedation Outcomes Efficacy Safety Pharmacokinetics

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Development of Tunable Silk Fibroin/Xanthan Biopolymeric Scaffold for Skin Tissue Engineering Using L929 Fibroblast Cells

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Journal of Bionic Engineering 2021年第1期18卷 103-117页

作者： Shailendra singh Shera Rathindra mohan Banik Bioprocess Technology Laboratory Sschool of Biochemical Engineeringndian Institute of Technology(Banaras Hindu University)Varanasi 221005India Department of Biotechnology Faculty of Engineering&TechnologyRAMA Universit Uittar PradeshKanpur 209217India

Skin acts as protective barrier against a number of factors such as dust,opportunistic microbial and viral infections,regulates body temperature and waste *** cell population plays an important role in devclopment of skin architecturc.A scaffold having capability to support and enhance fibroblast growth is a viable option for wound dressing material which can shorten the time for wound to *** this work,Silk Fibroin(SF)and Xanthan(Xa)were blended in three ratios 80 SF:20 Xa(SFX82),60 SF:40 Xa(SFX64),and 50SF:50 Xa(SFX55)to create SF/Xa *** and other physicochemical properties of SF/Xa scaffold are functions of blending ratios and blend with the ratio 80 SF:20 Xa has the highest *** properties of SF/Xa blends are a function of miscibility with SFX82 having superior thermal propertis of all fabricated *** porosity of SF/Xa scaffolds is in the range of 67%to 50%,with pore size of 58.1 um-45.5 um,water uptake capacity of 92%-86%,and surface roughness of 49.95 nm-385 ***82 shows highest growth rate of L929 fibroblast cells indicating its superiority over other scaffolds for providing biological cues for the growth and proliferation of fibroblastic cells in natural ***82 scaffold is found to be most suitable for fibroblastic cells thereby enhancing the tissue regeneration at wound site.

关键词： blends miscibility FTIR imaging Atomic Force Microscopy(AFM) cytocompatibility wound healing

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New atomic data for Kr XXXV useful in fusion plasma

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Chinese Physics B 2013年第3期22卷 282-288页

作者： Sunny Aggarwal Jagjit singh Man mohan Department of Physics and Astrophysics University of Delhi

Energy levels and emission line wavelengths of high-Z materials are useful for impurity diagnostics due to their potential application in the next generation fusion *** this purpose,we have calculated the fine structural energies of the 67 levels belonging to the 1s 2,1s2l,1s3l,1s4l,1s5l,and 1s6l configurations of Kr XXXV using GRASP（general purpose relativistic atomic structure package） ***,we have reported the transition probabilities,oscillator strengths,line strengths,and transition wavelengths for some electric dipole（E1） transitions among these *** predict new energy levels and radiative rates,which have not been reported experimentally or theoretically,forming the basis for future experimental work.

关键词： atomic data general purpose relativistic atomic structure package(GRASP) code transition probability

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