检索结果-南通市图书馆

Decoding molecular mechanisms:brain aging and Alzheimer's disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2279-2299页

作者： Mahnoor Hayat Rafay ali Syed Hammad Qaiser Mohammad Uzair Khalid Al-Regaiey Roaa Khallaf Lubna Abdullah mohammed Albassam Imdad Kaleem Xueyi Wang Ran Wang Mehwish SBhatti Shahid Bashir Atta-ur-Rahman School of Applied Biosciences(ASAB) National University of Sciences and Technology(NUST)IslamabadPakistan Department of Biotechnology Quaid-i-Azam UniversityIslamabadPakistan Department of Biological Sciences Faculty of Basic&Applied SciencesInternational Islamic University Islamabad(IIUI)IslamabadPakistan Department of Bioengineering King Fahd University of Petroleum and MineralsDhahranSaudi Arabia Department of Physiology College of MedicineKing Saud UniversityRiyadhSaudi Arabia Department of Neurology Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Mental Health Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Biosciences Commission on Science and Technology for Sustainable Development in the South(COMSATS University)IslamabadPakistan Department of Psychiatry The First Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Mental Health Institute of Hebei Medical University ShijiazhuangHebei ProvinceChina Department of Neurobiology and Behavior University of CaliforniaIrvineCAUSA Neuroscience Center King Fahad Specialist Hospital DammamDammamSaudi Arabia

The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for *** aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's *** these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging *** these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect *** review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.

关键词： Alzheimer’s disease brain aging cognitive health dementia molecular mechanisms neuronal activity neuroplasticity neurotransmission

△_(h)-GOULD-HOPPER APPELL POLYNOMIALS

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Acta Mathematica Scientia 2021年第4期41卷 1196-1222页

作者： Mehmet ali ÖZARSLAN banu YILMAZ YASAR Department of Mathematics Eastern Mediterranean UniversityFamagustaNorth Cyprus via Mersin 10Turkey

In this paper,we introduce the △_(h)-Gould-Hopper Appell polynomials An(x,y;h)via h-Gould-Hopper polynomials G_(n)^(h)(x,y).These polynomials reduces to △_(h)-Appell polynomials in the case y=0,△-Appell polynomials in the case y=0 and h=2D-Appell polynomials in the case h→0,2D △-Appell polynomials in the case h=1 and Appell polynomials in the case h→0 and y=*** obtain some well known main properties and an explicit form,determinant representation,recurrence relation,shift operators,difference equation,integro-difFerence equation and partial difference equation satisfied by *** satisfied by △_(h)-Gould-Hopper Appell polynomials reduce to determinant of all subclass of the usual ***,shift operators and difference equation satisfied by these polynomials reduce to recurrence,shift operators and difference equation of △_(h)-Appell polynomials,△-Appell polynomials;recurrence,shift operators,differential and integro-differential equation of 2D-Appell polynomials,recurrence,shift operators,integrodifference equation of 2D △-Appell polynomials,recurrence,shift operators,differential equation of Appell polynomials in the corresponding *** the special cases of the determining functions,we present the explicit forms,determinants,recurrences,difference equations satisfied by the degenerate Gould-Hopper Carlitz Bernoulli polynomials,degenerate Gould-Hopper Carlitz Euler polynomials,degenerate Gould-Hopper Genocchi polynomials,△_(h)-Gould-Hopper Boole polynomials and △_(h)-Gould-Hopper Bernoulli polynomials of the second *** particular cases of the degenerate Gould-Hopper Carlitz Bernoulli polynomials,degenerate Gould-Hopper Genocchi polynomials,△_(h)-Gould-Hopper Boole polynomials and △_(h)-Gould-Hopper Bernoulli polynomials of the second kind,corresponding determinants,recurrences,shift operators and difference equations reduce to all subclass of degenerate so-called families except for Genocchi polynomials recurrence,shift operators,an

关键词： △_(h)-Appell polynomials determinant recurrence difference equation

Generating Pairs for the Fischer Group Fi_(23)

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Algebra Colloquium 2020年第4期27卷 713-730页

作者： Faryad ali mohammed Al-Kadhi Department of Mathematics and Statistics College of Science Imam Mohammad Ibn Saud Islamic University(IMSIU)P.O.Box 90950Riyadh 11623Saudi Arabia

A group G is said to be(l,m,n)-generated if it is a quotient of the triangle groupT(l,m,n)=(x,y,z|x^(l)=y^(m)=z^(n)=xyz=1).Moori posed in 1993 the question of finding all the triples(l,m,n)such that non-abelian finite simple groups are(l,m,n)-*** partially answer this question for the Fischer sporadic simple group *** particular,we investigate all(2,q,r)-generations for the Fischer sporadic simple group Fi23,where q and r are distinct prime divisors of|Fi_(23)|.

关键词： generating pair Fischer group Fi_(23) sporadic group generating triple

Potential Antidiabetic and Anti-Genotoxic Activities of Silver Nanoparticles of Alkaloid Extract of Rhazya stricta in Rat Animal Model

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Phyton-International Journal of Experimental Botany 2021年第6期90卷 1749-1762页

作者： mohammed ali Ashehri Biology Department Faculty of ScienceUniversity of TabukTabuk47512Saudi Arabia

In most of Arabian courtiers Rhazya stricta is extensively utilized in public medicine for several diseases *** this study,crude alkaloid extract of ***(CAERS)coated with silver nanoparticles(CAERS-AgNPs)as potential treatment against diabetes in DM animal model was *** albino male rats(n=80)were injected with STZ to induce Diabetes Mellitus type-2(DM).DM-rats were injected different doses of CAERS or CAERS-nanoparticles(CAERS-NPs)for 2 *** results exhibited that mRNA expression of insulin and insulin receptor was down-regulated,activity levels of antioxidant enzymes were decreased,generation of ROS mediated DNA adducts and apoptosis in DM-rats was increased significantly than those in negative control *** contrast,the expression of insulin and insulin receptor genes was up-regulated,activity levels of antioxidant enzymes,ROS generation,DNA adducts and apoptosis incidence in DM-rats supplemented with high dose of CAERS and all doses of CAERS-NPs were *** conclusion:*** nanoparticles improved the anti-diabetic effect of the plant much more than the powder form of the *** action could be attributed to modification of the chemical and physical properties of the plant *** properties modification might be improved the ability of plant compounds to penetrate the cell membrane which facilitating release of plant materials into the target cells.

关键词： Diabetes Rhazya stricta nanotechnology gene expression DNA damage apoptosis

MoBShield:A Novel XML Approach for Securing Mobile Banking

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第5期79卷 2123-2149页

作者： Saeed Seraj ali Safaa Sadiq OmprakashKaiwartya Mohammad Aljaidi Alexandros Konios mohammed ali mohammed Abazeed Department of Computer Science Nottingham Trent UniversityClifton LaneNottinghamNG118NSUK Department of Computer Science Faculty of Information TechnologyZarqa UniversityZarqa13110Jordan Department of Computer Science King Khalid UniversityAbha61421Saudi Arabia

Mobile banking security has witnessed significant R&D attention from both financial institutions and *** is due to the growing number of mobile baking applications and their reachability and usefulness to ***,these applications are also attractive prey for cybercriminals,who use a variety of malware to steal personal banking *** literature in mobile banking security requiresmany permissions that are not necessary for the application’s intended security *** this context,this paper presents a novel efficient permission identification approach for securing mobile banking(MoBShield)to detect and prevent malware.A permission-based dataset is generated for mobile banking malware detection that consists large number of malicious adware apps and benign apps to use as training *** dataset is generated from 1650 malicious banking apps of the Canadian Institute of Cybersecurity,University of New Brunswick and benign apps from Google Play.A machine learning algorithm is used to determine whether amobile banking application ismalicious based on its permission ***,an eXplainable machine learning(XML)approach is developed to improve trust by explaining the reasoning behind the algorithm’s *** evaluation tests that the approach can effectively and practically identify mobile banking malware with high precision and reduced false ***,the adapted artificial neural networks(ANN),convolutional neural networks(CNN)and XML approaches achieve a higher accuracy of 99.7%and the adapted deep neural networks(DNN)approach achieves 99.6%accuracy in comparison with the state-of-the-art *** promising results position the proposed approach as a potential tool for real-world scenarios,offering a robustmeans of identifying and thwarting malware inmobile-based banking ***,MoBShield has the potential to significantly enhance the security and trustworthiness of

关键词： Security malware detection deep learning convolutional neural networks deep neural networks

Ding w-Flat Modules and Dimensions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Algebra Colloquium 2018年第2期25卷 203-216页

作者： Fuad ali Ahmed Almahdi mohammed Tamekkante Department of Mathematics Faculty of Sciences King Khalid University P. O. Box. 9004 Abha Saudi Arabia Laboratory MACS Faculty of Sciences University Moulay Ismail 5000 P.B. 11201 Zitoune Meknes Morocco

The introduction of w-operation in the class of flat modules has been successful. Let R be a ring. An R-module M is called a w-fiat module if Tor1r（M, N） is GV-torsion for all R-modules N. In this paper, we introduce the w-operation in Gorenstein homological algebra. An R-module M is called Ding w-flat if there exists an exact sequence of projective R-modules ... → P1 → P0 → p0 → p1 → ... such that M Im（P0 → p0） and such that the functor HomR （-,F） leaves the sequence exact whenever F is w-flat. Several well- known classes of rings are characterized in terms of Ding w-flat modules. Some examples are given to show that Ding w-flat modules lie strictly between projective modules and Gorenstein projective modules. The Ding w-flat dimension （of modules and rings） and the existence of Ding w-flat precovers are also studied.

关键词： w-fiat module and dimension Gorenstein projective module and dimension,strongly Gorenstein flat module

Geochemistry of magnetite in beach sands, stream sediments,and in situ magnetites in surrounding rocks at north Taiwan island

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Geochimica 2022年第3期41卷 434-452页

作者： Eslam mohammed ali Mitwally Bing-Sheng Yu Institute of Mineral Resources Engineering National Taipei University of TechnologyTaipeiTaiwanRepublic of China Geology Department Faculty of ScienceAl Azhar UniversityAsyuˆtEgypt

The geochemistry of magnetite provides constraints on the source(s) of the magnetite and other ore minerals. In this study, we constructed a magnetite distribution map, compared the chemical composition of magnetite present in hard rocks with that present in sand beach and stream deposits to determine magnetite’s provenance,investigated relationships among different trace elements,examined variations in the concentrations of trace elements present in magnetite, and identified the type of studied magnetite. Laser ablation inductively coupled plasma mass spectrometry(LA-ICP-MS) and inductively coupled plasma mass spectrometry/inductively coupled plasma atomic emission spectroscopy was used to analyze samples available in small and large amounts, respectively. The average magnetite compositions of beach and river samples were substantially similar to those of andesite rocks,revealing that the magnetite samples may have originated from surrounding andesite rocks;this finding is consistent with the chemical composition of the samples analyzed using LA-ICP-MS. Some of the andesite rocks found in the study area were the primary source of magnetite aggregations in the beach sands and stream sands near or slightly away from these rocks. High Ti–V magnetites lie within the fields of Fe–Ti–V bearing magnetite and titanomagnetite(ulv?spinel). These titanomagnetites may be undergoing transformation to spinel minerals such as galaxite,gahnite, magnesiochromite, and chromite, which are characterized by the high concentrations of Al, Ti, Mg, Cr,Ni, Mn, and Zn. The positive correlation between Fe and Ti, Cr and Ni, and also the negative correlation between Fe and Mg, Mn and Zn can be attributed to various magnetite phases present in the study area. V, Co, Mo, Nb, Ga, Sn,and Ta exhibited a positive correlation with Fe and a negative correlation with Al. The positive correlation between Fe and these elements indicates the enrichment of these elements in the magnetite series. We observ

关键词： Magnetite chemistry LA-ICP-MS Element incorporation Multi variation diagram Distribution map North Taiwan

New topological and non-topological unidirectional-wave solutions for the modifie d-mixe d KdV equation and bidirectional-waves solutions for the Benjamin Ono equation using recent techniques

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Ocean Engineering and Science 2022年第2期7卷 163-169页

作者： Marwan Alquran mohammed ali Hammad Jadallah Department of Mathematics and Statistics Jordan University of Science&TechnologyIrbid 22110Jordan

In this paper,new explicit unidirectional wave solutions for the modified-mixed KdV equation and bidi-rectional waves for the Benjamin Ono equation are *** extension of the rational sine-cosine and sinh-cosh methods are *** addition,an extension of the recent polynomial function method is applied as *** types of topological and non-topological soliton solutions are extracted to the proposed models and categorized by providing 2D and 3D ***,some physical properties of the new bidirectional waves solutions to the Benjamin Ono model are discussed.

关键词： Single-wave solutions Two-waves solutions Extended rational sine-cosine method Extended rational sinh-cosh method Polynomial-function method

Slicing-Based Enhanced Method for Privacy-Preserving in Publishing Big Data

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2022年第8期72卷 3665-3686页

作者： mohammed BinJubier Mohd Arfian Ismail Abdulghani ali Ahmed ali Safaa Sadiq Faculty of Computing Universiti Malaysia PahangKuantanPahangMalaysia School of Computer Science and Informatics De Montfort UniversityLeicesterLE19BHUnited Kingdom School of Engineering Computing and Mathematical SciencesUniversity of WolverhamptonWulfruna Street WolverhamptonWV11LYUnited Kingdom

Publishing big data and making it accessible to researchers is important for knowledge building as it helps in applying highly efficient methods to plan,conduct,and assess scientific ***,publishing and processing big data poses a privacy concern related to protecting individuals’sensitive information while maintaining the usability of the published *** anonymization methods,such as slicing and merging,have been designed as solutions to the privacy concerns for publishing big ***,the major drawback of merging and slicing is the random permutation procedure,which does not always guarantee complete protection against attribute or membership ***,merging procedures may generatemany fake tuples,leading to a loss of data utility and subsequent erroneous knowledge *** study therefore proposes a slicingbased enhanced method for privacy-preserving big data publishing while maintaining the data *** particular,the proposed method distributes the data into horizontal and vertical *** lower and upper protection levels are then used to identify the unique and identical attributes’*** unique and identical attributes are swapped to ensure the published big data is protected from disclosure *** outcome of the experiments demonstrates that the proposed method could maintain data utility and provide stronger privacy preservation.

关键词： Big data big data privacy preservation anonymization data publishing