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作者： mohammed aminu saleh 南京理工大学

学位级别：硕士

Tube hydroforming （THF） is currently an active area of development in the automotive industry on account of its advantages it offers in comparison to other manufacturing processes. In this paper, four simulations were carried out having the same cross sectional area but different axial feeding and load paths to improve the process design in THF process, in order to help establish the feasibility of the THF processes for specific components and have the potential to reduce the number of forming trials required to standardize the process for production of high quality hydroforming components. In addition, the studies also focus on development of an experiment simulation procedures for the entire hydroforming process. The simulation results focus on the % reduction thickness. It has also focus on the axial feed and load paths which becomes an important and useful method for planning the process design analysis, design of forming process and also planning of the tool. Since they play an important role and also determine accordance of forming limits such as wrinkling, bursting and crushing .The geometry model is analyzed base on different axial load and load paths. The key issues include geometry modeling, materials selection, meshing, boundary conditions, load definition and contact between the tube and the dies. On the base of the simulation, an optimized process parameter combination has obtained and has been verified by the instrument panel frame hydroforming experiment. The works show that: a. The hydroforming of an automotive part requires proper selection of process parameters, i.e. the internal pressure and axial feeds. b. The combination of the internal pressure and axial feeds are crucial to the success of the hydroforming operation. c. In order to reduce the trial-and-error effort in the designing of the process parameters, FEA simulations can help to determine the "optimum" process parameters and predict the forming results, such as % thic

关键词： Tube hydroforming Simulation Load path Process design 液压成型

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Robust Multi-Output Machine Learning Regression for Seismic Hazard Model Using Peak Crust Acceleration Case Study,Turkey,Iraq and Iran

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Journal of Earth Science 2023年第5期34卷 1447-1464页

作者： Shaheen mohammed saleh Ahmed Hakan Guneyli Department of Geology College of ScienceKirkuk UniversityKirkuk 36001Iraq Department of Geology Faculty EngineeringCukurova UniversityBalcali-Adana 01330Turkey

This paper for the first time improved a Robust Multi-Output machine learning regression model for seismic hazard zoning of Turkey, Iraq and Iran using constructed 3-D shear-wave velocity(Vs), seismic tomography dataset model for the crust and uppermost mantle beneath the study area. The focus of this paper’s opportunity is to develop a scientific framework leveraging machine learning that will ultimately provide the rapid and more complete characterization of earthquake properties. This work can be targeted at improving the seismic hazard zones system ability to detect and associate seismic signals, or at estimating other seismic characteristics(crust acceleration and crust energy) while traditionally, methods cannot monitor the earthquakes system. This work has derived some physical equations for extraction of many variables as inputs for our developed machine learning model based on a reliable understanding of the tomography data to physical variables by preparing huge dataset from different physical conditions of crust. We have extracted the velocity values of the shear waves from the original NETCDF file, which contains the S velocity values for every one km of the depths of the crust for the study area from one km down to the uppermost mantle beneath the Middle East. For the first time, this study calculated new seismic hazard parameter called Peak Crust Acceleration(PCA) for seismic hazard analysis by considering the transmitted initial seismic energy through the Earthy wrote in python language ’s crust layers from hypocenter. All machine learning algorithms in this studusing anaconda platform the open-source Individual Edition(Distribution).

关键词： robust multi-output regressor tomography peak crust acceleration NETCDF machine learning hazards

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Premature ejaculation:an update on definition and pathophysiology

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Asian Journal of Andrology 2019年第5期21卷 425-432页

作者： mohammed Abu El-Hamd Ramadan saleh Ahmad Majzoub department of Dermatology Venereology and AndrologyFaculty of MedicineSohag UniversitySohag 82749Egypt Department of Urology Hamad Medical Corporation and Weill Cornell Medicine-QatarDoha 00974Qatar

Premature ejaculation(PE)is the most comm on male sexual dysfunction,which represents a diag no stic as well as a therapeutic challenge for ***,no universally accepted definition is currently available for *** a result,physicians continue to diagnose patients with PE according to major guidelines set by the professional *** guidelines either recommend the use of validated questionnaires or patient-reported *** efforts directed toward classifying PE may help provide a better understanding of the prevalence and risk factors of this *** the exact etiology of PE has not been clearly elucidated,several risk factors have been strongly reported in the ***,to understand the revised definition of PE,its etiology and pathophysiology is necessary to improve the clinical management of this medical condition and form the basis of future research in this *** this review,we highlight the past and current definitions of PE and present an appraisal on the classifications and theories suggested for the etiopathogenesis of PE.

关键词： ejaculatory disorders male sexual dysfunction premature ejaculation

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Decoding molecular mechanisms:brain aging and Alzheimer's disease

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Neural Regeneration Research 2025年第8期20卷 2279-2299页

作者： Mahnoor Hayat Rafay Ali Syed Hammad Qaiser Mohammad Uzair Khalid Al-Regaiey Roaa Khallaf Lubna Abdullah mohammed Albassam Imdad Kaleem Xueyi Wang Ran Wang Mehwish SBhatti Shahid Bashir Atta-ur-Rahman School of Applied Biosciences(ASAB) National University of Sciences and Technology(NUST)IslamabadPakistan Department of Biotechnology Quaid-i-Azam UniversityIslamabadPakistan Department of Biological Sciences Faculty of Basic&Applied SciencesInternational Islamic University Islamabad(IIUI)IslamabadPakistan Department of Bioengineering King Fahd University of Petroleum and MineralsDhahranSaudi Arabia Department of Physiology College of MedicineKing Saud UniversityRiyadhSaudi Arabia Department of Neurology Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Mental Health Neuroscience CenterKing Fahad Specialist HospitalDammamSaudi Arabia Department of Biosciences Commission on Science and Technology for Sustainable Development in the South(COMSATS University)IslamabadPakistan Department of Psychiatry The First Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Mental Health Institute of Hebei Medical University ShijiazhuangHebei ProvinceChina Department of Neurobiology and Behavior University of CaliforniaIrvineCAUSA Neuroscience Center King Fahad Specialist Hospital DammamDammamSaudi Arabia

The complex morphological,anatomical,physiological,and chemical mechanisms within the aging brain have been the hot topic of research for *** aging process alters the brain structure that affects functions and cognitions,but the worsening of such processes contributes to the pathogenesis of neurodegenerative disorders,such as Alzheimer's *** these observable,mild morphological shifts,significant functional modifications in neurotransmission and neuronal activity critically influence the aging *** these changes is important for maintaining cognitive health,especially given the increasing prevalence of age-related conditions that affect *** review aims to explore the age-induced changes in brain plasticity and molecular processes,differentiating normal aging from the pathogenesis of Alzheimer's disease,thereby providing insights into predicting the risk of dementia,particularly Alzheimer's disease.

关键词： Alzheimer’s disease brain aging cognitive health dementia molecular mechanisms neuronal activity neuroplasticity neurotransmission

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Highlights in pathogenesis of vitiligo

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World Journal of Clinical Cases 2015年第3期3卷 221-230页

作者： Ghada F mohammed Amal Hussein Gomaa mohammed saleh Al-Dhubaibi Department of Dermatology and Venereology Faculty of Medicine Suez Canal University Department of Dermatology Faculty of Medicine Qassim University

Vitiligo is a common pigmentary disorder. Many studies across decades and all over the world have attempted to illustrate the pathogenesis behind it; however, the pathogenesis of vitiligo remains elusive. This review article, we present the findings behind the most and updated theories behind this psychologically debilitating and disfiguring disease. The discussion begun with the role of genetic predisposition followed by neural theory first proposed in the 1950 s. Wehighlight the autoimmune hypothesis, followed by the reactive oxygen species model, zinc-α2-glycoprotein deficiency hypothesis, viral theory, intrinsic theory and biochemical, molecular and cellular alterations accounting for loss of functioning melanocytes in vitiligo. Many theories were elaborated to clarify vitiligo pathogenesis. It is a multifactorial disease involving the interplay of several factors. Future research is needed to clarify the interaction of these factors for better understanding of vitiligo pathogenesis and subsequent successful treatment.

关键词： Etiopathogenesis Pigmentary disorder Non-segmental vitiligo Segmental vitiligo Vitiligo

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Hypoglycemic Potential of African Medicinal Plants in Diabetic and Non-Diabetic Human Subjects: A Review

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Clinical Complementary Medicine and Pharmacology 2023年第2期3卷 39-49页

作者： aminu mohammed Department of Biochemistry Ahmadu Bello University81000 ZariaKaduna StateNigeria

Africa is blessed with several plants and marine organisms used to treat various diseases including *** folkloric use of some of these plants in treating diabetes has been documented in various databases and publi-cations,and validated using various diabetes ***,most of the investigations on African medicinal plants as antidiabetic agents are not taken beyond proof-of-concept ***,limited number of clinical trials were conducted to validate the efficacy in humans and the few available clinical studies have not been critically ***,this review is intended to document the antidiabetic potential of African medici-nal plants investigated in human subjects as well their safety *** articles were harvested from the major scientific databases(Scopus,PubMed,and Google Scholar).According to the present search,eighteen(18)African medicinal plants and one herbal formulation were the only plants investigated for antidiabetic ac-tivity in *** plants showed no noticeable toxicity throughout the study ***,all the 18 plant species were traditionally used to treat diabetes in various parts of *** variations in the study period and dosages used,Laportea ovalifolia(Schumach.&Thonn.)Chew.(Urticaceae)and Momordica charantia L.(Cucurbitaceae)were the most effective as they reduced fasting blood glucose by>50%after 10 days and 4 weeks treatment periods,*** available information revealed that African medicinal plants espe-cially *** and *** should be subjected to phase III clinical trial,aimed at getting the natural product-based antidiabetic drugs from Africa.

关键词： African medicinal plants Diabetes Clinical trial Hyperglycemia Safety

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Analysing the Severity and Frequency of Traffic Crashes in Riyadh City Using Statistical Models

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International Journal of Transportation Science and Technology 2012年第4期1卷 351-364页

作者： saleh Altwaijri mohammed Quddus Abigail Bristow School of Civil Engineering Loughborough UniversityLoughboroughLE113TUUK

Traffic crashes in Riyadh city cause losses in the form of deaths,injuries and property damages,in addition to the pain and social tragedy affecting families of the *** 2005,there were a total of 47,341 injury traffic crashes occurred in Riyadh city(19%of the total KSA crashes)and 9%of those crashes were *** safety in Riyadh city may have been adversely affected by:high car ownership,migration of people to Riyadh city,high daily trips reached about 6 million,high rate of income,low-cost of petrol,drivers from different nationalities,young drivers and tremendous growth in population which creates a high level of mobility and transport activities in the *** primary objective of this paper is therefore to explore factors affecting the severity and frequency of road crashes in Riyadh city using appropriate statistical models aiming to establish effective safety policies ready to be implemented to reduce the severity and frequency of road crashes in Riyadh *** data for Riyadh city were collected from the Higher Commission for the Development of Riyadh(HCDR)for a period of five years from 1425H to 1429H(roughly corresponding to 2004-2008).Crash data were classified into three categories:fatal,serious-injury and *** nominal response models have been developed:a standard multinomial logit model(MNL)and a mixed logit model to injury-related crash *** to a severe underreporting problem on the slight injury crashes binary and mixed binary logistic regression models were also estimated for two categories of severity:fatal and serious *** frequency,two count models such as Negative Binomial(NB)models were employed and the unit of analysis was 168 HAIs(wards)in Riyadh ***-level crash data are disaggregated by severity of the crash(such as fatal and serious injury crashes).The results from both multinomial and binary response models are found to be fairly consistent but the results from the random parameters model seem mo

关键词： income injuries nominal

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A Reliable NLP Scheme for English Text Watermarking Based on Contents Interrelationship

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Computer Systems Science & Engineering 2021年第6期37卷 297-311页

作者： Fahd N.Al-Wesabi saleh Alzahrani Fuad Alyarimi mohammed Abdul Nadhem Nemri mohammed M.Almazah Department of Computer Science King Khalid UniversityMuhayel AseerKingdom of Saudi Arabia Faculty of Computer and IT Sana’a UniversitySana’aYemen Department of Information Systems King Khalid UniversityMuhayel AseerKingdom of Saudi Arabia Department of Mathematics and computer in Ibb University Yemen and Department of MathematicsKing Khalid UniversityMuhayel AseerKingdom of Saudi Arabia

In this paper,a combined approach CAZWNLP(a combined approach of zero-watermarking and natural language processing)has been developed for the tampering detection of English text exchanged through the *** third gram of alphanumeric of the Markov model has been used with text-watermarking technologies to improve the performance and accuracy of tampering detection issues which are limited by the existing works reviewed in the literature of this *** third-grade level of the Markov model has been used in this method as natural language processing technology to analyze an English text and extract the textual characteristics of the given ***,the extracted features have been utilized as watermark information and then validated with the attacked English text to detect any suspected tampering occurred on *** embedding mechanism of CAZWNLP method will be achieved logically without effects or modifying the original text document to embed a watermark *** has been implemented using VS code IDE with *** experimental and simulation results using standard datasets of varying lengths show that the proposed approach can obtain high robustness and better detection accuracy of tampering common random insertion,reorder,and deletion attacks,e.g.,Comparison results with baseline approaches also show the advantages of the proposed approach.

关键词： NLP text analysis English text watermarking robustness tampering detection

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Two-stage procedure in the management of selected cases of keratoconus: clear lens extraction with aspherical IOL implantation followed by WFG-PRK

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International Journal of Ophthalmology(English edition) 2018年第11期11卷 1761-1767页

作者： Waleed Abou Samra Tharwat Mokbel mohammed Elwan Sameh saleh Ahmed Elwehidy mohammed Iqbal Adel Ellayeh Department of Ophthalmology Faculty of Medicine Mansoura University Department of Ophthalmology Faculty of Medicine Sohag University

AIM： To assess the objective and subjective results of a two-stage procedure for management of keratoconus： clear lensectomy with aspherical intraocular lens（IOL） implantation followed by wave front-guided photorefractive keratotomy（WFG-PRK）.METHODS： This prospective interventional non-randomized study included patients aged 35 years old or more with grade I and II stable keratoconus, a clear visual axis, minimal corneal thickness（MCT） 420 μm or more and average keratometric reading（K） less than 54 diopter（D）. Refraction of all selected eyes should be-8.00 D sphere or more with less than-6.00 D cylinder and could be corrected two lines or more with spectacles or contact lenses. All studied eyes underwent a two-stage approach treatment： first refractive lens exchange and aspherical IOL implantation followed, after at least 3 mo, by WFGPRK. Pre and postoperative complete ophthalmological examination were performed. Topographical, visual and aberrometric results were recorded and evaluated during 6 mo follow up period. Moreover, patient satisfaction and other subjective outcomes were also ***： The 13 eyes of 11 patients diagnosed with stable keratoconus and aged from 39 to 49 y（42.4±6.2 y） were enrolled in the study. At baseline, 8 eyes had grade I and 5 eyes had grade II keratoconus. The manifest sphere was-10.3±4.2 D（ranged from-8.0 to-14.0 D） and the manifest cylinder was-4.2±1.2 D（ranged from-1.75 to-5.50 D）. After the two-stage procedure, sphere and cylinder reduced significantly to-0.43±0.22 D and-1.3±0.72 D respectively（P〈0.001）. There was also a highly significant improvement in the mean uncorrected distance visual acuity（UDVA） from logMAR 1.41±0.49 preoperatively to 0.51±0.16 postoperatively（P〈0.001） and the mean corrected distance visual acuity（CDVA） from 0.76±0.24 preoperatively to 0.49±0.13 after the operation（P〈0.001）. All aberrometric and mesopic vision parameters and most of the topographical indices demonstrated highly significant improveme

关键词： keratoconus clear lensectomy wave front guided photorefractive keratotomy

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Analogue Modelling of Fold-and-Thrust Belts Controlled by Multiple Detachment Layers: An Example from the Eastern Sichuan Basin

Analogue Modelling of Fold-and-Thrust Belts Controlled by Mu...

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作者： mohammed saleh Ahmed Gaghman 中国石油大学(华东)

学位级别：硕士

四川盆地位于中国西南部,经历了复杂的构造演化过程,也是中国油气资源最为丰富的盆地之一。四川盆地东部褶皱带(简称“川东褶皱带”)以发育隔档式褶皱为主要构造特征,构造变形较为复杂。同时,在川东褶皱带,发现了三套塑性滑脱层分别为... 详细信息

四川盆地位于中国西南部,经历了复杂的构造演化过程,也是中国油气资源最为丰富的盆地之一。四川盆地东部褶皱带(简称“川东褶皱带”)以发育隔档式褶皱为主要构造特征,构造变形较为复杂。同时,在川东褶皱带,发现了三套塑性滑脱层分别为中下寒武统膏盐岩、志留系泥岩、中下三叠统膏盐岩。以这三套滑脱层为界可将川东地层划分为三套构造层:深部寒武系-奥陶系构造层(以中下寒武统膏盐岩滑脱层为底界),中部石炭系-二叠系构造层(以志留系泥岩滑脱层为底界)和浅部中生界构造层(以中下三叠统膏盐岩滑脱层为底界)。三套滑脱层将川东地区垂向上划分为上中、下三套构造层,各构造层之间的构造变形具有显著差异。尽管前人已经针对川东褶皱带开展了大量的研究工作并取得了一定的认识,然而关于这三套滑脱层对川东褶皱带构造变形过程所起到的控制作用尚待明确。本文在地震解译和构造平衡恢复的基础之上,结合多滑脱层砂箱物理模拟实验开展研究,重点探讨川东地区多套滑脱层对川东褶皱带构造变形的控制作用。首先,通过地震解译和构造平衡恢复(Midland Valley),刻画出川东褶皱带的构造特征,其构造平衡恢复结果表明:川东褶皱带最大缩短量为26.13km(缩短率约为20.34%),最大缩短速率为0.090 mm/a。在此基础上,根据川东褶皱带地层发育特点和构造特征,设置了五组构造物理模拟实验,通过控制滑脱层数量、滑脱层厚度、缩短量与缩短速率等参数,模拟和研究川东褶皱带构造变形的运动学过程,并定量评价了构造变形的过程。实验结果表明,滑脱层配置(数量、垂向分布等)和变形速率对川东多套滑脱层发育区的构造变形样式及构造演化过程具有重要的控制作用:(1)深部滑脱层的拆离效果显著强于浅部滑脱层,导致垂向上深部构造层内的构造变形差异性高于浅部构造层(2)缩短速率减小时,滑脱层的拆离效果明显增加,各构造层变形样式的差异性也随之增强。结合地震资料和砂箱模拟实验结果分析,推测川东地区在早期弱挤压变形阶段(缩短速率较低),其三套滑脱层的拆离作用明显,以发育滑脱褶皱及小型调节断层为主要构造变形特征,同时各构造层变形特征产生了明显的垂向差异性;在后期强烈挤压变形阶段(缩短速率快速提升),缩短速率限制了各滑脱层的拆离作用,各构造层以发育高陡逆冲断层和反冲断层为主,变形特征趋于一致。

关键词：四川盆地褶皱冲断带多滑脱层构造平衡恢复构造物理模拟

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