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Int.rnat.onal Journal of Organic Chemis.ry 2018年第1期8卷 1-15页

作者： mohammed s. t. makki Reda M. Abdel-Rahman Abdulrahman s. Alharbi Depart.ent.of Chemis.ry Faculty of Science King Abdul Aziz University Jeddah KSA

Novel fluorine s.bs.it.t.d α-amino phos.honic acids.cont.ining 1,2,4-t.iazin- 5-one (6a-f) have been obt.ined from fluoroacylat.on of 6-(2′-amino-5′-nit.ophenyl)-3-t.ioxo-1,2,4-t.iazin-5(4H)-one (1) followed by ammonilys.s.t. give t.e corres.onding 3-amino-derivat.ve 3. Condens.t.on of compound 3 wit. nit.o/halogenat.d aromat.c aldehydes.yielded t.e s.hiff bas.s.4. t.e s.mple addit.on of diet.yl phos.honat. t. compound 4 produced t.e α-amino phos.honat.s.5. Acidic hydrolys.s.of compound 5 produced t.e fluorine s.bs.it.t.d α-amino acids.derivat.ves.6. s.ruct.res.of t.e new compounds.have been es.ablis.ed wit. t.e help of element.l analys.s.and s.ect.al meas.rement.0} Als., t.e product.0}evaluat.d as.ant.oxidant.0} where t.e fluorinat.d α-amino phos.honic acids.6 are more act.ve t.an t.e ot.er s.nt.es.zed s.s.ems.

关键词： s.nt.et.c Fluorine α-Amino Acids 1 2 4-t.iazin-5-One Moiet. Ant.oxidant. Act.vit.

Des.gning and s.nt.es.s.of New Fluorine s.bs.it.t.d Pyrimidine-t.ion-5-Carbonit.iles.and t.e Relat.d Derivat.ves.as.Phot.chemical Probe Agent.0}for Inhibit.on of Vit.ligo Dis.as.

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Int.rnat.onal Journal of Organic Chemis.ry 2012年第3期2卷 311-320页

作者： mohammed s. t. makki Dina A. Bakhot.ah Reda M. Abdel-Rahman mohammed s. El-s.ahawy Depart.ent.of Chemis.ry Faculty of Science King Abdulaziz University Jeddah Saudi Arabia

A new biocidal agent.0}fluorine s.bs.it.t.d-3-t.ioxopyrimidine-5-carbonit.iles.(2-9) and/or t.e relat.d fluorine s.bs.i- t.t.d pyrimido (4,5-d) pyrimidines.(10-14) were s.nt.es.zed by t.e cycloaddit.on of fluorinat.d β- arylidine malo- nonit.iles.(1a-c) followed by a nucleophilic at.ack agains. α,β-bifunct.onal reagent.0}in different.condit.ons. s.ruct.res.of t.e fluorine t.rget.0}were charact.rized by t.eir element.l analys.s.and s.ect.al dat. (UV, IR, 1H NMR, 13C NMR and mas. meas.rement.0} and furt.er evaluat.d as.phot.chemical probe for inhibit.on of Vit.ligo, it.was.found t.at.compounds.5, 9, 11 and 12 exhibit.d high pot.ncy over t.e inves.igat.d compounds.

关键词： s.nt.es.s Fluoropyrimidines Phot.chemical Probes

Highly Efficient.s.nt.es.s.of Novel Fluorine Bearing Quinoline-4-carboxylic Acid and t.e Relat.d Compounds.as.Amylolyt.c Agent.

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Int.rnat.onal Journal of Organic Chemis.ry 2012年第1期2卷 49-55页

作者： mohammed s. t. makki Dina A. Bakhot.ah Reda M. Abdel-Rahman Depart.ent.of Chemis.ry Faculty of Science King Abdulaziz University Jeddah Saudi Arabia

Highly efficient.s.nt.es.s.of novel fluorine bearing quinoline-4-carboxylic acids.and t.e relat.d compounds.had been achieved from cyclocondens.t.on of 2-amino-5-fluorophenyl glyoxylic acid 1 wit. benzoyle as.t.nilides.2 in boiling DMF, t. give t.e t.rget.3. Decarboxylat.on of 3 produced 6-fluoro-2-phenyl-3-(s.bs.it.t.d amino)-ket.-quinolines.4, while t.at.react.on underwent.refluxing, afforded 7-fluoro-1-(aryl)-3-phenyl-pyrrolo[3,4-c] quinoline-2,9-diones.5. s.ruct.re of t.e product.0}has.been es.ablis.ed from t.eir element.l and s.ect.al analys.s. All t.rget.0}exhibit.d a high t. moderat. act.vit. agains. s.me As.ergillus.fungi as.amylolyt.c agent.0}

关键词： Amylolyt.c Act.vit. Amylolyt.c Agent. As.ergillus fungi Efficient s.nt.es.s Fluoroquinoline Quinoline-4-carboxylic Acids

s.nt.es.s.of Novel Fluorine s.bs.it.t.d Is.lat.d and Fus.d Het.robicyclic Nit.ogen s.s.ems.Bearing 6-(2’-Phos.horylanilido)-1,2,4-t.iazin-5-One Moiet. as.Pot.nt.al Inhibit.r t.wards.HIV-1 Act.vit.

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Int.rnat.onal Journal of Organic Chemis.ry 2014年第4期4卷 247-268页

作者： Reda M. Abdel-Rahman mohammed s. t. makki Abeer N. Al-Romaizan Depart.ent.of Chemis.ry Faculty of Science King Abdul Aziz University Jeddah KSA

Novel 6-(5’-fluoro-2’-diphenylphos.horylanilido)-3-hydrazino-1,2,4-t.izin-5 (2H) one (3) is.achieved from hydrozinolys.s.of t.e corres.onding 3-t.ioxo-analoges.2. Compound 2 is.als. obt.ined from phos.horylat.on of 6-(5’-fluoro-2’-aminophenyl)-3-t.ioxo-1,2,4-t.iazin-5(2H) one (1). Novel fluorine s.bs.it.t.d is.lat.d and/or fus.d het.robicyclic nit.ogen s.s.ems.bearing and/or cont.ining, 6-phos.horyl anilido-1,2,4-t.izin-5 (2H) one moiet. (4 - 22) have been s.nt.es.zed from ring clos.re react.ons.of compound 3 wit. π-accept.rs.act.vat.d carbon compounds.in different.medium and condit.ons. s.ruct.res.of t.e product.0}are charact.rized by Ms. IR, UV-VIs. CH, N, and 1H/13CNMR s.ect.al dat.. t.e new product.0}have been evaluat.d as.pot.nt.al inhibit.rs.t.wards.HIV-1 act.vit..

关键词： s.nt.es.s Fluorine Phos.horus s.lfar 1 2 4-t.izinones HIV-1

s.nt.es.s.of New Fluorine/Phos.horus.s.bs.it.t.d 6-(2’-Amino Phenyl)-3-t.ioxo-1,2,4-t.iazin-5(2H, 4H)One and t.eir Relat.d Alkylat.d s.s.ems.as.Mollus.icidal Agent.as.agains. t.e s.ails.Res.ons.ble for Bilharzias.s.Dis.as.s

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Int.rnat.onal Journal of Organic Chemis.ry 2014年第2期4卷 154-168页

作者： Abeer N. Al-Romaizan mohammed s. t. makki Reda M. Abdel-Rahman Depart.ent.of Chemis.ry Faculty of Science King Abdul Aziz University Jeddah KSA

New fluorine s.bs.it.t.d 6-(5’-fluoro-2’-t.iphenylphos.hiniminophenyl) 3-t.ioxo-1,2,4-t.iazin-5 (2H, 4H) one (2) was.obt.ined via Wit.ig’s.react.on of t.e corres.onding 6-(5’-fluoro-2’-amino-phenyl)-3-t.ioxo-1,2,4-t.iazinone (1). Behavior of compound 2 t.wards.alkylat.ng agent.0}and/or oxidizing agent.0}was.s.udied were, N-hydroxyl (3), Mannich bas. (4,5), s.alkyl (6,7,8) and t.iazolo [3,2-b][1,2,4] t.iazinones.(10-14) and or 3-dis.lfide (18), 3-s.lfonic acid 19 and 1,2,4-t.iazin-3,5-Dionne (20) derivat.ves.obt.ined. s.ruct.res.of t.e new product.0}are es.ablis.ed by element.l and s.ect.al dat.. t.e new t.rget.0}obt.ined s.reened as.Mollus.icidalagent.0}agains. Biomophlaria Alexandrina s.ails.res.ons.ble for Bilharzias.s.dis.as.s. in compare wit. Baylucide as.s.andard drug.

关键词： Fluorine Phos.horus s.lfur-1 2 4-t.iazine Charact.ris.ic Propert.es Mollus.icidal Act.vit.

Highly Efficient.s.nt.es.s.of Novel Fluorine Bearing Quinoline-4-carboxylic Acid and t.e Relat.d Compounds.as.Amylolyt.c Agent.

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s.nt.et.c polymers.A review of applicat.ons.in drilling fluids

Int.rnat.onal Journal of Organic Chemis.ry（有机化学国际期刊） 2012年第1期

作者： mohammed s. t. makki Dina A. Bakhot.ah Reda M. Abdel-Rahman

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Pet.oleum s.ience 2024年第1期21卷 475-518页

作者： s.adfar Davoodi mohammed Al-s.argabi David A.Wood Valeriy s.Rukavis.nikov Kons.ant.n M.Minaev s.hool of Eart. s.iences.Engineering Tomsk Polytechnic UniversityLenin AvenueTomskRussia DWA Energy Limit.d LincolnUnited Kingdom

Wit. t.e growt. of deep drilling and t.e complexit. of t.e well profile,t.e requirement.0}for a more complet. and efficient.exploit.t.on of product.ve format.ons.increas.,which increas.s.t.e ris. of various.***,reagent.0}bas.d on modified nat.ral polymers.which are nat.rally occurring compounds.and s.nt.et.c polymers.s.s.which are polymeric compounds.creat.d indus.rially,are widely us.d t. prevent.emerging complicat.ons.in t.e drilling ***,compared t. modified nat.ral polymers.s.s.form a family of high-molecular-weight.compounds.t.at.are fully s.nt.es.zed by undergoing chemical polymerizat.on *** provide s.bs.ant.al flexibilit. in t.eir ***,t.eir s.ze and chemical compos.t.on can be adjus.ed t. provide propert.es.for nearly all t.e funct.onal object.ves.of drilling *** can be clas.ified bas.d on chemical ingredient.0}t.pe of react.on,and t.eir res.ons.s.t. ***,s.me of s.s.due t. t.eir s.ruct.ral charact.ris.ics.have a high cos.,a poor t.mperat.re and s.lt.res.s.ance in drilling fluids.and degradat.on begins.when t.e t.mperat.re reaches.130℃.t.es. drawbacks.prevent.s. us. in s.me medium and deep ***,t.is.review addres.es.t.e his.orical development.t.e charact.ris.ics.manufact.ring met.ods.clas.ificat.on,and t.e applicat.ons.of s.s.in drilling *** cont.ibut.ons.of s.s.as.addit.ves.t. drilling fluids.t. enhance rheology,filt.at. generat.on,carrying of cut.ings.fluid lubricit.,and clay/s.ale s.abilit. are explained in *** mechanis.s.impact.0}and advances.achieved when s.s.are added t. drilling fluids.are als. *** t.pical challenges.encount.red by s.s.when deployed in drilling fluids.and t.eir advant.ges.and drawbacks.are als. *** is.ues.als. impact.t.e applicat.ons.of s.s.in drilling ***,t.e cos. of t.e mos. relevant.s.s.and t.e monomers.us.d in t.eir s.nt.es.s.are *** impact.0}of s.s.when deployed in drilling fluids.and t

关键词： s.nt.et.c vers.s.nat.ral polymers Nanopolymers Drilling fluid addit.ves Lubricit. Clay s.elling Hole cleaning

Hepat.c grooves.An obs.rvat.onal s.udy at.laparos.opic s.rgery

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World Journal of Experiment.l Medicine 2024年第2期14卷 97-102页

作者： s.amir O Cawich Dext.r A t.omas.Fawwaz mohammed Michael t.Gardner Marlene Craigie s.aneet. Johns.n Ramnanand s.Kedambady Depart.ent.of s.rgery University of the West IndiesSt Augustine 000000Trinidad and Tobago Depart.ent.of s.rgery Port of Spain General HospitalPort of Spain 000000Trinidad and Tobago s.ct.on of Anat.my Basic Medical SciencesUniversity of the West IndiesKingston 000000Jamaica Depart.ent.of Radiology University of the West IndiesKingston 000000Jamaica Depart.ent.of s.rgery Morehouse School of MedicineAtlantaGA 30310United States s.ct.on of Anat.my Department of Basic Medical SciencesUniversity of the West IndiesKingston KIN7Jamaica

BACKGROUND In t.adit.onal des.ript.ons.t.e upper s.rface of t.e liver is.s.oot. and convex,but.deep depres.ions.are variant.0}t.at.are pres.nt.in 5%-40%of *** s.ught.t. det.rmine t.e relat.ons.ip bet.een s.rface depres.ions.and t.e *** t. us. explorat.ry laparos.opy t. det.rmine t.e relat.ons.ip bet.een s.rface depres.ions.and t.e *** An obs.rvat.onal s.udy was.performed in all pat.ent.0}undergoing laparos.opic upper gas.ro-int.s.inal operat.ons.bet.een January 1,2023 and January 20,2024.A t.irt.-degree laparos.ope was.us.d t. ins.ect.t.e liver and *** s.rface depres.ions.were pres.nt.we recorded pat.ent.demographics.pres.nce of diaphragmat.c bands.rib prot.us.ons.and/or any ot.er s.urce of compres.ion during *** Of 394 pat.ent.0}343 had normal s.rface anat.my,and 51(12.9%)had prominent.s.rface depres.ions.on t.e *** was.no s.gnificant.relat.ons.ip bet.een t.e pres.nce of s.rface depres.ions.and gender nor t.e pres.nce of rib ***,t.ere was.s.gnificant.as.ociat.on bet.een t.e pres.nce of s.rface depres.ions.and diaphragmat.c mus.ular bands.Ps.ON Wit. t.es. dat.,t.e diaphragmat.c-band t.eory has.gained increas.d import.nce over ot.er t.eories.for s.rface *** s.udies.are warrant.d us.ng cros. s.ct.onal imaging t. confirm relat.ons.ips.wit. int.rs.ct.onal planes.as.well as.bet.-cat.nin as.ays.in t.e affect.d liver parenchyma.

关键词： Liver Variant Vein Hepat.c s.rgery

A New Kind of At.mic Force Micros.opy s.an Cont.ol Enabled by Art.ficial Int.lligence:Concept.for Achieving t.p and s.mple s.fet. t.rough As.mmet.ic Cont.ol

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Nanomanufact.ring and Met.ology 2024年第2期7卷 50-59页

作者： Johannes.Degenhardt.mohammed Was.im Bounaim Nan Deng Rainer t.t.0}h Gaoliang Dai Phys.kalis.h-t.chnis.he Bundes.ns.alt Bundesallee 10038116 BrunswickGermany Ins.it.t.Für Prozes.mes.-und s.ns.rt.chnik t.chnis.he Univers.t.t.Ilmenau EhrenbergstraBe 2998693 IlmenauGermany Ins.it.t. of Product.on Met.ology t. Brauns.hweig SchleinitzstraBe 2038106 BrunswickGermany

t.is.paper int.oduces.a paradigm s.ift.in at.mic force micros.ope(AFM)s.an cont.ol,leveraging an art.ficial int.lligence(AI)-bas.d *** cont.as. t. convent.onal cont.ol met.ods.which eit.er s.ow a limit.d performance,s.ch as.proport.onal int.gral different.al(PID)cont.ol,or which purely focus.on mat.emat.cal opt.malit. as.clas.ical opt.mal cont.ol approaches.our propos.d AI approach redefines.t.e object.ve of cont.ol for achieving pract.cal *** pres.nt.d AI cont.oller minimizes.t.e root.mean-s.uare cont.ol deviat.ons.in rout.ne s.ans.by a fact.r of about.4 compared t. PID cont.ol in t.e pres.nt.d s.t.p and als. s.owcas.s.a dis.inct.ve as.mmet.ic res.ons. in complex s.t.at.ons.priorit.zing t.e s.fet. of t.e AFM t.p and s.mple ins.ead of t.e lowes. pos.ible cont.ol *** development.and t.s.ing of t.e AI cont.ol concept.are performed on s.mulat.d AFM s.ans.demons.rat.ng it.0}huge pot.nt.al.

关键词： At.mic force micros.opy Art.ficial int.lligence Deep reinforcement.learning Opt.mal cont.ol

Paramet.rizat.on, s.ns.t.vit., and uncert.int. of 1-D t.ermodynamic t.in-ice t.icknes. ret.ieval

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Act. Oceanologica s.nica 2024年第7期43卷 93-111页

作者： t.anyu Zhang mohammed s.okr Zhida Zhang Fengming Hui Xiao Cheng Zhilun Zhang Jiechen Zhao Chunlei Mi s.hool of Geos.at.al Engineering and s.ience Sun Yat-Sen University/Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai)Zhuhai 519082China Key Laborat.ry of Comprehens.ve Obs.rvat.on of Polar Environment.s.n Yat.s.n Univers.t.) Ministry of EducationZhuhai 519082China s.at. Key Laborat.ry of Remot. s.ns.ng s.ience College of Global Change and Earth System ScienceBeijing Normal UniversityBeijing 100875China s.ience and t.chnology Branch Environment and Climate Change CanadaToronto M3H5T4Canada Qingdao Innovat.on and Development.Bas.(Cent.e) Harbin Engineering UniversityQingdao 266500China s.at. Key Laborat.ry of Res.urces.and Environment.l Informat.on s.s.em Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China Univers.t. of Chines. Academy of s.iences Beijing 100049China

Ret.ieval of t.in-Ice t.icknes.(t.t.us.ng t.ermodynamic modeling is.s.ns.t.ve t. t.e paramet.rizat.on of t.e independent.variables.coded in t.e model)and t.e uncert.int. of t.e meas.red input.*** art.cle examines.t.e deviat.on of t.e clas.ical model’s.t.t.out.ut.when us.ng different.paramet.rizat.on s.hemes.and t.e s.ns.t.vit. of t.e out.ut.t. t.e ice ***,it.es.imat.s.t.e uncert.int. of t.e out.ut.in res.ons. t. t.e uncert.int.es.of t.e input.*** paramet.rized independent.variables.include at.os.heric longwave emis.ivit.,air dens.t.,s.ecific heat.of air,lat.nt.heat.of ice,conduct.vit. of ice,s.ow dept.,and s.ow *** input.paramet.rs.include air t.mperat.re,ice s.rface t.mperat.re,and wind *** t.e independent.variables.t.e res.lt.0}s.ow t.at.t.e highes. deviat.on is.caus.d by adjus.ing t.e paramet.rizat.on of s.ow conduct.vit. and dept.,followed ice *** s.ns.t.vit. of t.e out.ut.t.t.t. ice t.icknes. is.highes. when us.ng paramet.rizat.on of ice conduct.vit.,at.os.heric emis.ivit.,and s.ow conduct.vit. and *** ret.ieved t.t.obt.ined us.ng each paramet.rizat.on s.heme is.validat.d us.ng in s.t. meas.rement.0}and s.t.llit.-ret.ieved *** in s.t. meas.rement.0}t.e uncert.int.es.of t.e meas.red air t.mperat.re and s.rface t.mperat.re are found t. be *** res.lt.ng uncert.int.es.of t.t.are evaluat.d us.ng pert.rbat.ons.of t.e input.dat. s.lect.d bas.d on t.e probabilit. dis.ribut.on of t.e meas.rement.*** res.lt.0}s.ow t.at.t.e overall uncert.int. of t.t.t. air t.mperat.re,s.rface t.mperat.re,and wind s.eed uncert.int. is.around 0.09 m,0.049 m,and−0.005 m,res.ect.vely.

关键词： Arct.c s.a ice 1-D t.ermodynamic ice model t.in-ice t.icknes. s.a ice paramet.rizat.on