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Frequency of Uveitis among Juvenile Idiopathic Arthritis Patients in a Tertiary Care Hospital of Bangladesh: A Retrospective Study

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Open Journal of Rheumatology and Autoimmune Diseases 2024年第3期14卷 144-156页

作者： Md. Asif ali Mujammel Haque Kamrul Laila mohammad Hafiz Al-Mamun Mohammed Mahbubul Islam mohammad Imnul Islam Manik Kumar Talukder Pediatric Rheumatology Division Department of Pediatrics Bangabandhu Sheikh Mujib Medical University Dhaka Bangladesh

Background: Juvenile idiopathic arthritis (JIA) is the most frequently encountered pediatric rheumatologic disorder with an unknown etiology. At present there is no published data regarding the frequency of uveitis in patients with JIA in Bangladesh. This study aimed to observe the frequency of JIA-associated uveitis (JIAU) and distribution of uveitis among different sub-categories of JIA at the Pediatric Rheumatology division, both outdoor and indoor patients, Department of Pediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU) in Bangladesh. Methods: This was a retrospective study of 1784 JIA patients at the Pediatric Rheumatology division, BSMMU from July 2010 to March 2023. Results: Among the 1784 enrolled JIA patients, we observed that 0.73% of cases had uveitis. Here, 61.5% of JIAU cases were male. Most of the cases (92.3%) had bilateral uveitis and only 7.7% cases had unilateral uveitis. Among JIAU patients, the majority were Oligo JIA (53.8%), followed by ERA 30.8%, Poly JIA RF(−) 7.7% and Systemic JIA 7.7% cases respectively. This study also revealed that 15.4% of JIAU patients had ANA positivity and 23% had HLA B-27 positivity. Here we also found ocular complications associated with uveitis such as band keratopathy (23.1%), posterior synechiae (15.4%) and cataract (15.4%). Conclusions: In this study, we observed only 0.73% of patients of JIA had developed uveitis which is lower than the frequency observed in other European studies. This study also showed various ocular complications amongst JIA-associated uveitis patients which signifies the importance of adherence to periodic ophthalmological follow-up to prevent these ocular complications.

关键词： JIA Uveitis HLA-B27 ANA BSMMU

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Geyser Inspired Algorithm:A New Geological-inspired Meta-heuristic for Real-parameter and Constrained Engineering Optimization

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Journal of Bionic Engineering 2024年第1期21卷 374-408页

作者： Mojtaba Ghasemi Mohsen Zare Amir Zahedi mohammad-Amin Akbari Seyedali Mirjalili Laith Abualigah Department of Electronics and Electrical Engineering Shiraz University of TechnologyShirazIran Department of Electrical Engineering Faculty of EngineeringJahrom UniversityJahromFrasIran Department of Electrical and Computer Engineering Tarbiat Modares UniversityTehranIran Department of Electrical and Computer Engineering University ofCyprusNicosiaCyprus Centre for Artificial Intelligence Research and Optimisation Torrens University AustraliaBrisbaneQLD 4006Australia University Research and Innovation Center Obuda University1034 BudapestHungary Department of Electrical and Computer Engineering Lebanese American UniversityByblos 13-5053Lebanon Hourani Center for Applied Scientific Research Al-Ahliyya Amman UniversityAmman 19328Jordan MEU Research Unit Middle East UniversityAmman 11831Jordan Applied Science Research Center Applied Science Private UniversityAmman 11931Jordan

Over the past years,many efforts have been accomplished to achieve fast and accurate meta-heuristic algorithms to optimize a variety of real-world *** study presents a new optimization method based on an unusual geological phenomenon in nature,named Geyser inspired Algorithm(GEA).The mathematical modeling of this geological phenomenon is carried out to have a better understanding of the optimization *** efficiency and accuracy of GEA are verified using statistical examination and convergence rate comparison on numerous CEC 2005,CEC 2014,CEC 2017,and real-parameter benchmark ***,GEA has been applied to several real-parameter engineering optimization problems to evaluate its *** addition,to demonstrate the applicability and robustness of GEA,a comprehensive investigation is performed for a fair comparison with other standard optimization *** results demonstrate that GEA is noticeably prosperous in reaching the optimal solutions with a high convergence rate in comparison with other well-known nature-inspired algorithms,including ABC,BBO,PSO,and *** that the source code of the GEA is publicly available at https://***/projects/gea.

关键词： Nature-inspired algorithms Real-world and engineering optimization Mathematical modeling Geyser algorithm(GEA)

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Improvement of Surface Mechanical and Tribological Characteristics of L-PBF Processed Commercially Pure Titanium through Ultrasonic Impact Treatment

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Acta Metallurgica Sinica(English Letters) 2024年第6期37卷 1034-1046页

作者： Iman Ansarian Reza Taghiabadi Saeid Amini mohammad Hossein Mosallanejad Luca Iuliano Abdollah Saboori Department of Materials Science and Metallurgy Imam Khomeini International University(IKIU)QazvinIran Department of Mechanical Engineering University of KashanKashanIran Integrated Additive Manufacturing Center Department of Management and Production EngineeringPolitecnico di TorinoCorso Duca Degli Abruzzi 2410129TurinItaly

Multi-pass ultrasonic impact treatment(UIT)was applied to modify the microstructure and improve the mechanical and tribological characteristics at the near-surface region of commercially pure Ti(CP-Ti)specimens produced by the laser powder bed fusion(L-PBF)*** considerably refined the L-PBF process-related acicular martensites(α′-M)and produced a well-homogenized and dense surface microstructure,where the porosity content of 1-,3-,and 5-pass UITed samples was reduced by 43,60,and 67%,*** UITed samples showed an enhancement in their near-surface mechanical properties up to a depth of about 300μ*** nanoindentation results for the 3-pass UITed sample revealed an increase of about 53,45,and 220%in its nanohardness,H/E_(r),and H_(3)/E_(r)^(2)indices,*** stylus profilometry results showed that performing the UIT removed the L-PBF-related features/defects and offered a smooth *** roughness average(R_(a))and the skewness(R_(sk))of the 3-pass UITed sample were found to be lower than those of the L-PBFed sample by 95 and 223%,*** the UIT also enhanced the material ratio,where the maximum load-bearing capacity(~100%)in as-L-PBFed(as-built)and 3-pass UITed samples was obtained at 60-and 10-µm depths,*** tribological investigations showed that applying the UIT resulted in a significant reduction of wear rate and average coefficient of friction(COF)of *** instance,under the normal pressures of 0.05 and 0.2 MPa,the wear rate and COF of the 3-pass UITed sample were lower than those of the L-PBFed sample by 65 and 58%,and 20 and 17%,respectively.

关键词： Laser powder bed fusion Ultrasonic impact treatment Commercially pure Ti(CP-Ti) Surface mechanical properties Tribological properties

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Er_(2)TiO_(5)@Ag nanocomposites:Enhanced photocatalysis and bacteria inactivation,and cytotoxicity

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Journal of Rare Earths 2024年第5期42卷 851-858,I0002页

作者： Mehdi Nazeri Hossein Sedaghat Reza Rafiei mohammad Amin Farzin Seyed Mostafa Hosseinpour Mashkani Department of Parasitology and Mycology Kashan University of Medical SciencesKashanIran Department of Microbiology Kashan University of Medical SciencesKashanIran General Medicine Student School of MedicineKashan University of Medical SciencesKashanIran Student Research Committee Kashan University of Medical SciencesKashanIran Institute for Biomedical Materials and Devices School of Mathematical and Physical SciencesFaculty of ScienceUniversity of Technology SydneyNSW2007Australia

In this study,we successfully synthesized Er_(2)TiO_(5)@Ag nanocomposites(NCPs) using the ultrasonicmediated sol-gel technique to create a multifunctional material with enhanced photocatalytic and antibacterial *** visible light photocatalytic activities of Er_(2)TiO_(5) nanoparticles(NPs) and Er_(2)TiO_(5)@Ag NCPs were systematically evaluated under various conditions,including different concentrations of Basic Blue 41(BB 41) dye and *** results reveal a remarkable improvement in the photocatalytic degradation efficiency of Er_(2)TiO_(5)@Ag NCPs(95%) compared to Er_(2)TiO_(5) NPs(80%).Furthermore,the antibacterial efficacy of Er_(2)TiO_(5) NPs and Er2TiO_5@Ag NCPs were extensively examined against Gram-positive and Gram-negative ***,Er_(2)TiO_(5)@Ag NCPs exhibit significantly higher minimum bactericidal concentration(MBC) values compared to Er_(2)TiO_(5) *** antibacterial effect of Er_(2)TiO_(5)@Ag NCPs is particularly pronounced against *** and Pseudomonas aeruginosa,while demonstrating moderate effects on Escherichia coli and Enterococcus *** assess the biocompatibility of the synthesized materials,we investigated their internalization by MCF-7 ***,both Er_(2)TiO_(5) NPs and Er_(2)TiO_(5)@Ag NCPs are found to be effectively internalized by the cells,suggesting their potential application in biomedical ***,our study unveils the exceptional potential of Er_(2)TiO_(5)@Ag NCPs as a dual-action solution,simultaneously possessing enhanced photocatalytic efficiency and potent antibacterial *** multifunctional nanocomposite not only outperforms Er_(2)TiO_(5) and Ag but also paves the way for innovative applications in sustainable environmental remediation and advanced biomedical technologies,promising a brighter and cleaner future.

关键词： Rare earth catalysis Nanocomposite Er_(2)TiO_(5)@Ag Antibacterial activity Photocatalysis Cytotoxicity

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A Stacking Machine Learning Model for Student Performance Prediction Based on Class Activities in E-Learning

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Computer Systems Science & Engineering 2024年第5期48卷 1251-1272页

作者： mohammad Javad Shayegan Rosa Akhtari Department of Computer Engineering University of Science and CultureTehran***Iran

After the spread of COVID-19,e-learning systems have become crucial tools in educational systems worldwide,spanning all levels of *** widespread use of e-learning platforms has resulted in the accumulation of vast amounts of valuable data,making it an attractive resource for predicting student *** this study,we aimed to predict student performance based on the analysis of data collected from the OULAD and Deeds *** stacking method was employed for modeling in this *** proposed model utilized weak learners,including nearest neighbor,decision tree,random forest,enhanced gradient,simple Bayes,and logistic regression *** a trial-and-error process,the logistic regression algorithm was selected as the final learner for the proposed *** results of experiments with the above algorithms are reported separately for the pass and fail *** findings indicate that the accuracy of the proposed model on the OULAD dataset reached 98%.Overall,the proposed method improved accuracy by 4%on the OULAD dataset.

关键词： Stacking e-learning student performance prediction machine learning classification

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Highly efficient vanadium redox flow batteries enabled by a trilayer polybenzimidazole membrane assembly

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Carbon Energy 2024年第7期6卷 191-204页

作者： Trung Tuyen Bui Mingyu Shin mohammad Rahimi Anders Bentien Yongchai Kwon Dirk Henkensmeier Hydrogen·Fuel Cell Research Center Korea Institute of Science and Technology(KIST)SeoulRepublic of Korea Department of Chemical and Biomolecular Engineering Seoul National University of Science and TechnologySeoulRepublic of Korea Department of Biological and Chemical Engineering Aarhus UniversityAarhusDenmark KIST School Division of Energy and Environment TechnologyUniversity of Science and TechnologySeoulRepublic of Korea Graduate School of Energy and Environment Korea UniversitySeoulRepublic of Korea

A novel polybenzimidazole(PBI)-based trilayer membrane assembly is developed for application in vanadium redox flow battery(VRFB).The membrane comprises a 1μm thin cross-linked poly[2,2′-(p-oxydiphenylene)−5,5′-bibenzimidazole](OPBI)sandwiched between two 20μm thick porous OPBI membranes(p-OPBI)without further lamination *** trilayer membrane demonstrates exceptional properties,such as high conductivity and low area-specific resistance(ASR)of 51 mS cm−1 and 81mΩcm^(2),*** with vanadium electrolyte increases the ASR of trilayer membrane only to 158mΩcm^(2),while that of Nafion is 193mΩcm^(2).VO^(2+)permeability is 2.73×10^(-9) cm^(2) min^(−1),about 150 times lower than that of Nafion *** addition,the membrane has high mechanical strength and high chemical stability against VO^(2+).In VRFB,the combination of low resistance and low vanadium permeability results in excellent performance,revealing high Coulombic efficiency(>99%),high energy efficiency(EE;90.8%at current density of 80mA cm^(−2)),and long-term *** EE is one of the best reported to date.

关键词： polybenzimidazole porous membrane proton conductivity trilayer VRFBs

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Suitability of SDN and MEC to facilitate digital twin communication over LTE-A

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Digital Communications and Networks 2024年第2期10卷 347-354页

作者： Hikmat Adhami mohammad Alja’afreh Mohamed Hoda Jiaqi Zhao Yong Zhou Abdulmotaleb El Saddik Mohamed bin Zayed University of Artificial Intelligence Masdar CityAbu DhabiUnited Arab Emirates School of Computer Science and Technology China University of Mining and TechnologyXuzhou221116China School of Electrical Engineering and Computer Science University of OttawaOttawaONK1N 6N5Canada

Haptic is the modality that complements traditional multimedia,i.e.,audiovisual,to evolve the next wave of innovation at which the Internet data stream can be exchanged to enable remote skills and control *** will require ultra-low latency and ultra-high reliability to evolve the mobile experience into the era of Digital Twin and Tactile *** the 5th generation of mobile networks is not yet widely deployed,Long-Term Evolution(LTE-A)latency remains much higher than the 1 ms requirement for the Tactile Internet and therefore the Digital *** work investigates an interesting solution based on the incorporation of Software-defined networking(SDN)and Multi-access Mobile Edge Computing(MEC)technologies in an LTE-A network,to deliver future multimedia applications over the Tactile Internet while overcoming the QoS *** network scenarios were designed and simulated using Riverbed modeler and the performance was evaluated using several time-related Key Performance Indicators(KPIs)such as throughput,End-2-End(E2E)delay,and *** best scenario possible is clearly the one integrating MEC and SDN approaches,where the overall delay,jitter,and throughput for haptics-attained 2 ms,0.01 ms,and 1000 packets per *** results obtained give clear evidence that the integration of,both SDN and MEC,in LTE-A indicates performance improvement,and fulfills the standard requirements in terms of the above KPIs,for realizing a Digital Twin/Tactile Internet-based system.

关键词： LTE-A 5G Digital twin Tactile Internet KPIs SDN MEC NFV Haptic

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Electrospun Aloe Vera Extract Loaded Polycaprolactone Scaffold for Biomedical Applications:A Promising Candidate for Corneal Stromal Regeneration

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Journal of Bionic Engineering 2024年第4期21卷 1949-1959页

作者： Amin Orash Mahmoud Salehi mohammad Rafienia Narsimha Mamidi Saeed Heidari Keshel alireza Baradaran-Rafii Department of Chemistry and Nanotechnology School of Engineering and ScienceTecnologico de MonterreyMonterreyNuevo Leon64849Mexico Biosensor Research Center Isfahan University of Medical SciencesIsfahan81746-73461Iran Wisconsin Center for NanoBioSystems School of PharmacyUniversity of Wisconsin-MadisonMadisonWisconsin53705USA Medical Nanotechnology Research Center Shahid Beheshti University of Medical SciencesTehran19857-17443Iran Department of Ophthalmology Ophthalmic Research CenterLabbafinejad Medical CenterShahid Beheshti University of Medical SciencesTehran19395-4631Iran Department of Ophthalmology Morsani College of MedicineUniversity of South FloridaTampaFL33612USA Department of Tissue Engineering and Applied Cell Science School of Advanced Technologies in MedicineShahid Beheshti University of Medical SciencesTehran19857-17443Iran

Corneal diseases,the second leading cause of global vision loss affecting over 10.5 million people,underscores the unmet demand for corneal tissue *** the scarcity of fresh donor corneas and the associated risks of immune rejection,corneal tissue engineering becomes *** nanofibrous scaffolds that mimic the natural corneal structure is crucial for creating transparent and mechanically robust corneal equivalents in tissue ***,Aloe Vera Extract(AVE)/Polycaprolactone(PCL)nanofibrous scaffolds were primed using *** electrospun AVE/PCL fibers exhibit a smooth,bead-free morphology with a mean diameter of approximately 340±95 nm and appropriate light *** measurements reveal Young’s modulus and ultimate tensile strength values of around 3.34 MPa and 4.58 MPa,respectively,within the range of stromal *** addition,cell viability of AVE/PCL fibers was measured against Human Stromal Keratocyte Cells(HSKCs),and improved cell viability was *** cell-fiber interactions were investigated using scanning electron *** conclusion,the incorporation of Aloe Vera Extract enhances the mechanical,optical,hydrophilic,and biological properties of PCL fibers,positioning PCL/AVE fiber scaffolds as promising candidates for corneal stromal regeneration.

关键词： Corneal stromal regeneration Aloe vera extract Polycaprolactone Electrospinning

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Levisticum officinale extract protects against CCl4-induced hepatotoxicity through anti-inflammatory,anti-fibrotic,and antioxidant properties in rats

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Asian Pacific Journal of Tropical Biomedicine 2024年第8期14卷 331-340页

作者： Nahid Ghaedi Iran Pouraboli Mansour Mirtadzadini mohammad-mehdi Moeini-aghtaie Department of Biology Faculty of SciencesShahid Bahonar University of KermanKermanIran Department of Pathology Pathology and Stem Cell Research CenterAfzalipour Medical FacultyKerman University of Medical SciencesKermanIran

Objective:To investigate the hepatoprotective effects of Levisticum officinale extract on CCl4-induced ***:Different doses of Levisticum officinale extract were given orally to rats for 10 days,then rats received a single dose of CCl4(2.5 mL/kg,50%v/v in liquid paraffin).Biochemical and histopathological assays were performed to assess the effects of the extract on liver function and ***,antioxidant and oxidative markers as well as inflammatory and fibrotic indicators were ***:Pretreatment with Levisticum officinale extract significantly mitigated CCl4-induced damage to liver structure,improved serum levels of alanine aminotransferase,aspartate aminotransferase,alkaline phosphatase,urea,total bilirubin,and total protein,enhanced glutathione content and superoxide dismutase and catalase activities in the liver,as well as decreased plasma and hepatic malondialdehyde *** results demonstrated that the extract reduced Ki-67 andα-SMA expression and Masson’s trichrome staining revealed decreased liver collagen in rats treated with Levisticum officinale ***,Levisticum officinale extract markedly decreased the gene expressions of TNF-α,IL-6,TGF-β1,MCP-1,and ***:Levisticum officinale extract exerts hepatoprotective effects on CCl4-induced hepatotoxicity through antioxidant,anti-inflammatory,and anti-fibrotic activities.

关键词： Levisticum officinale CCl4 Inflammation Liver toxicity Antioxidant

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Respiratory complications of propofol,sevoflurane,and dexmedetomidine anesthesia for fiberoptic bronchoscopy in children aged 1 month to 3 years:a randomized trial

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南方医科大学学报 2024年第9期44卷 1631-1636页

作者： Amir Shafa mohammad Montasery Sedighe Shahhosseini Majid Keivanfar Asieh Maghami Mehr Mahtab Ebrahim Babaei mohammad Jafari Department of Anesthesiology Anesthesiology and Critical Care Research Center Department of Pediatrics Isfahan University of Medical SciencesIsfahanIran Department of Statistics Yazd UniversityYazdIran Departments of Obstetrics and Gynecology Shahrekord University of Medical SciencesShahrekordIran

Objective To evaluate the effect of propofol,sevoflurane,and dexmedetomidine on respiratory complications inchildren undergoing fiberoptic bronchoscopy(FOB).Methods This double-blind randomized clinical trial was conductedamong 120 children aged 1 month to 3 years undergoing *** patients were randomized into 3 groups(n=40)foranesthesia induction with sevoflurane inhalation,1 mg/kg propofol,or 1μg/kg dexmedetomidine before bronchoscopy,andthe changes in hemodynamic parameters,sedation level,and respiratory complications during and after the procedure *** The patients'heart rate during bronchoscopy was significantly lower and the mean arterial blood pressuresignificantly higher in dexmedetomidine group than in sevoflurane and propofol groups(P<0.05).Cough duringbronchoscopy did not occur in any of the cases in propofol group,while the highest frequency of cough was recorded indexmedetomidine *** incidence of laryngospasm in the propofol group(12.5%)was significantly lower than those insevoflurane and dexmedetomidine groups(30%and 32.5%,respectively)(P<0.05).Conclusion Sevoflurane and propofol aresafe and suitable for anesthesia induction in children below 3 years of age undergoing diagnostic FOB and can achieve bettersedative effect and lower the incidences of cough and respiratory complications as compared with dexmedetomidine.

关键词： fiberoptic bronchoscopy propofol sevoflurane dexmedetomidine children

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