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Nipah Virus Unveiled: A Review Article

Advances in Bioscience and Biotechnology 2024年第3期15卷 161-173页

作者： Munama Magdum Md. Abir Tazim Chowdhury Mahmuda Khandaker Razdip Datta Md. Naheed Rayhan Md. Siffat uddin Md. Junayed Imam Bhuiyan Md. Ahaduzzaman Md. Abdullah Al-Mahammud Kabir mohammad Zishan uddin Md. Estiak Ullah Sahid Subrata Saha Department of Community Medicine Shaheed Monsur Ali Medical College Dhaka Bangladesh Department of Cardiothoracic and Vascular Surgery Evercare Hospital Dhaka Bangladesh Department of Microbiology Shaheed Monsur Ali Medical College Dhaka Bangladesh Department of Anesthesia Dhaka Dental College & Hospital Dhaka Bangladesh Department of Cardiothoracic Anesthesia Evercare Hospital Dhaka Bangladesh Department of Medicine Times Multicare Hospital Ltd. Dhaka Bangladesh Barking Havering and Redbridge University Hospitals NHS Trust Romford UK

Nipah virus (NiV) is a highly infectious zoonotic pathogen that poses a significant threat to human and animal health. First identified in Malaysia in 1998, NiV has since caused several outbreaks in Southeast Asia, with sporadic cases reported in Bangladesh and India. The virus is primarily transmitted to humans through direct contact with infected animals, primarily fruit bats, or through the consumption of contaminated fruits and their juices. NiV infection presents a wide spectrum of clinical features, ranging from mild respiratory illness to severe encephalitis, with a high case fatality rate. The incubation period typically ranges from 4 to 14 days, during which patients develop fever, headache, myalgia, and respiratory symptoms such as cough and sore throat. As the disease progresses, neurological signs become prominent, including altered consciousness, seizures, and focal deficits. Severe cases may exhibit acute respiratory distress syndrome and multi organ failure. Laboratory findings often include lymphocytopenia, thrombocytopenia, and elevated liver enzymes. Diagnosis of NiV infection requires specialized laboratory testing, including reverse transcription-polymerase chain reaction (RT-PCR) and serological assays. Currently, no specific antiviral treatment exists for NiV infection, and management primarily focuses on supportive care. Prevention and control strategies encompass public health interventions, surveillance, and raising awareness among healthcare providers and the general population. The emergence and re-emergence of NiV highlight the urgent need for continued research, improved diagnostic capabilities, and the development of effective vaccines and therapeutics to mitigate the impact of this deadly virus.

关键词： Nipah Virus Zoonotic Pathogen Outbreaks Surveillance

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The Efficacy of Deep Learning-Based Mixed Model for Speech Emotion Recognition

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Computers, Materials & Continua 2023年第1期74卷 1709-1722页

作者： mohammad Amaz uddin mohammad Salah uddin Chowdury Mayeen uddin Khandaker Nissren Tamam Abdelmoneim Sulieman Department of Computer Science and Engineering BGC Trust University BangladeshChittagong4381Bangladesh Centre for Applied Physics and Radiation Technologies School of Engineering and TechnologySunway UniversityBandar SunwaySelangor47500Malaysia Department of Physics College of SciencesPrincess Nourah bint Abdulrahman UniversityP.O Box 84428Riyadh11671Saudi Arabia Department of Radiology and Medical Imaging Prince Sattam bin Abdulaziz UniversityAlkharjSaudi Arabia

Human speech indirectly represents the mental state or emotion of *** use of Artificial Intelligence(AI)-based techniques may bring revolution in this modern era by recognizing emotion from *** this study,we introduced a robust method for emotion recognition from human speech using a well-performed preprocessing technique together with the deep learning-based mixed model consisting of Long Short-Term Memory(LSTM)and Convolutional Neural Network(CNN).About 2800 audio files were extracted from the Toronto emotional speech set(TESS)database for this study.A high pass and Savitzky Golay Filter have been used to obtain noise-free as well as smooth audio data.A total of seven types of emotions;Angry,Disgust,Fear,Happy,Neutral,Pleasant-surprise,and Sad were used in this ***,Fundamental frequency,and Mel Frequency Cepstral Coefficient(MFCC)have been used to extract the emotion features,and these features resulted in 97.5%accuracy in the mixed LSTM+CNN *** mixed model is found to be performed better than the usual state-of-the-art models in emotion recognition from *** also indicates that this mixed model could be effectively utilized in advanced research dealing with sound processing.

关键词： Emotion recognition Savitzky Golay fundamental frequency MFCC neural networks

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Improved systemic half-life of glucagon-like peptide-1-loaded carbonate apatite nanoparticles in rats

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World Journal of Diabetes 2022年第8期13卷 613-621页

作者： Nabilah Ibnat Rahela Zaman mohammad Borhan uddin Ezharul Chowdhury Chooi Yeng Lee School of Medicine and Health Sciences Monash University MalaysiaSubang Jaya 47500SelangorMalaysia School of Pharmacy Monash University MalaysiaSubang Jaya 47500SelangorMalaysia

BACKGROUND Glucagon-like peptide-1(GLP1)is an endogenous peptide that regulates blood glucose *** its susceptibility to rapid metabolic degradation limits its therapeutic *** To prepare GLP1-encapsulated nanosize particle with controlled release property to improve the systemic half-life of *** GLP1 nanoparticles were prepared by complexation of GLP1 with carbonate apatite nanoparticles(CA NPs).The physicochemical properties of the CA NPs,the effects of GLP1-loaded CA NPs on cell viability,and the systemic bioavailability of GLP1 after CA NPs administration were *** The GLP1-loaded CA NPs was within 200 nm in size and stable in fetal bovine *** formulation did not affect the viability of human cell lines suggesting that the accumulation of CA NPs in target tissues is *** Sprague Dawley rats,the plasma GLP1 Levels as measured from the GLP1-loaded CA NPs-treated rats,were significantly higher than that of the control rats and free GLP1-treated rats at 1 h post-treatment(P<0.05),and the level remained higher than the other two groups for at least 4 *** The GLP1-loaded CA NPs improved the plasma half-life of *** systemic bioavailability of GLP1 is longer than other GLP1 nanoparticles reported to date.

关键词： Glucagon-like peptide-1 Metabolic syndrome Nanoparticles Plasma half-life Rat

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Comparing the Cost and Time of Tender Opening Committee Report Preparation for Manual and E-Procurement Tenders in the Roads and Highways Department of Bangladesh

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Open Journal of Applied Sciences 2022年第3期12卷 336-345页

作者： Md. Abdur Rashid mohammad Shorif uddin Bangladesh University of Professionals Dhaka Bangladesh Department of Computer Science and Engineering Jahangirnagar University Savar Bangladesh

Bangladesh’s public procurement system has been traditional, i.e., a manual tendering system, under the legislative guidance of PPA-2006 and PPR-2008. Manual tendering has long been a source of concern for public procurement agencies regarding tender opening related to cost and time. To resolve this challenge and make the dream of a Digital Bangladesh a reality, the Government of Bangladesh launched the e-Procurement system in 2011 under the flagship of e-GP Guidelines. Following the successful pilot testing conducted under the umbrella of the CPTU, all public PEs are attempting to implement electronic procurement tenders. This study aims to examine the cost and time involved in preparing Tender Opening Committee (TOC) Reports for manual and e-procurement tenders in Bangladesh’s Roads and Highways Department. A mixed-method was used to collect data from the population of 11 RHD zones, including KII and primarily survey questionnaires. The independent samples t-test was used to compare data and hypothesis tests from two groups using SPSS software. The results indicated that e-Procurement tendering, tender opening preparation costs and time were more efficient than manual tendering. Academicians, students, practitioners, researchers, and policymakers will benefit from the study’s conclusions. Additionally, the government will be urged to improve policies such as the PPA 2006, the PPR 2008, and the 2011 e-GP Guideline.

关键词： e-GP Guideline 2011 e-Procurement Tender Opening Committee Report Preparation t-Test TOC Meeting

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Comparing the Efficiency of Manual and Electronic Tender Document Preparation: Cost and Time Context

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Intelligent Information Management 2022年第6期14卷 195-201页

作者： Md. Abdur Rashid mohammad Shorif uddin Bangladesh University of Professionals Dhaka Bangladesh Department of Computer Science and Engineering Jahangirnagar University Savar Bangladesh

In Bangladesh, both manual and e-GP system is used to perform public procurement. Before tender publication, tender documents have to be prepared by the Procurement Entities (PEs). The problem is that the manual tendering system involves more cost and time in preparing tender documents. The study’s purpose is to compare now the efficiency of tender document preparation in the manual system with the e-GP system. This study tests the cost and time involved in tender document preparation, both manual and e-procurement tenders. Sample data was collected from the 11 RHD zones. Structured survey questionnaires were used to collect primary data from the PE officers of RHD. A hypothesis test was performed using the model of independent samples t-test. The test results indicated that e-Procurement tender document preparation costs and time were less than manual tendering. Academicians, researchers, PE officers, and policymakers will benefit from the study’s conclusions.

关键词： Tender Document Preparation Cost Tender Document Preparation Time E-Procurement T-Test E-GP System Public Procurement RHD

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Contact Stress and Wear Analysis of Zirconia Against Alumina for Normal and Physically Demanding Loads in Hip Prosthesis

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Journal of Bionic Engineering 2020年第5期17卷 1045-1058页

作者： Subramaniam Shankar Rajavel Nithyaprakash Palanisamy Sugunesh mohammad uddin Alokesh Pramanik Department of Mechatronics Engineering Kongu Engineering CollegeErodeTamilNaduIndia Department of Mechanical Engineering Kongu Engineering CollegeErodeTamilNaduIndia University of South Australia UniSA STEMMawson Lakes CampusMawson LakesSA 5095Australia School of Civil and Mechanical Engineering Curtin UniversityBentleyWAAustralia

Risky gait activities lead to severe wear in orthopaedic implants during postoperative *** aim of the present study is to predict the linear and volumetric wear of zirconia(ZrO2)vs alumina(Al2O3)hip implants subject to risky and normal gait ***,the gait loads pertaining to risky gait activities were converted to equivalent normal *** using the computed normal loads,friction and wear coefficients of ZrO2 ball against Al2O3 disc were calculated from Pin-on-Disc(POD)tribometer under dry and lubricating *** solution,a bio-lubricant was utilized for lubrication purpose to mimic synovial fluid *** gait activities stair ascending or descending,carrying load,lifting load and ladder up or down etc.,grouped as A,B,C and D were used to determine friction and wear *** Element Method(FEM)was employed to predict the wear of the bearing *** developed contact pressure for these gait activities was then utilized to compute linear and volumetric wear for 2 million *** findings suggests that,patients regularly involved in group C and D type gait activities were likely to cause more wear which may accelerate early implant failure.

关键词： hip implants gait activities pin-on-disc lubrication FEM wear

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Flow and erosion at a bend in the braided Jamuna River

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International Journal of Sediment Research 2012年第4期27卷 498-509页

作者： mohammad Nazim uddin Md.Munsur RAHMAN Department of Civil Engineering Dhaka University of Engineering and Technology Institute of Water and Flood Management Bangladesh University of Engineering and Technology

The braided Jamuna River frequently changes its *** the secondary channel in a braided river acts as a single thread meandering *** the present study an attempt has been made to investigate the flow patterns and to estimate the rate of bank erosion in a bend along the Jamuna *** three dimensional(3D) flow velocities were measured using Acoustic Doppler Current Profiler(ADCP).It is found that the near bank velocity is amplified by 1.1 to 1.3 times as compared with the section averaged velocity.A dominant secondary current is found in the upstream *** evolution as well as decay of the secondary current is not as clear as it is found in the laboratory *** is revealed from the analysis of the flow process that the causes of higher rate of erosion at the study bend are the oblique flow near bankline,six times amplified shear velocity than critical shear velocity near bankline and the secondary current which acts as a sediment transporting agent from the outer bank towards the inner bank or the sand *** on the flow processes,a simplified erosion prediction model is developed and applied to estimate the rate of erosion at a selected *** the predicted results have been compared with the observed data at the bend and all the available data at other bends along the Jamuna River.

关键词： Braided Jamuna River Bend Flow pattern Erosion prediction model

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Impact of industrial effluent on growth and yield of rice(Oryza sativa L.) in silty clay loam soil

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Journal of Environmental Sciences 2015年第4期27卷 231-240页

作者： mohammad Anwar Hossain Golum Kibria Muhammad Mustafizur Rahman mohammad Mizanur Rahman Abul Hossain Molla mohammad Mostafizur Rahman mohammad Khabir uddin Department of Environmental Sciences Jahangirnagar University Department of Soil Science Bangabandhu Sheikh Mujibur Rahman Agricultural University Department of Bioenvironmental Science Bangabandhu Sheikh Mujibur Rahman Agricultural University

Degradation of soil and water from discharge of untreated industrial effluent is alarming in Bangladesh. Therefore, buildup of heavy metals in soil from contaminated effluent, their entry into the food chain and effects on rice yield were quantified in a pot experiment. The treatments were comprised of 0, 25%, 50%, 75% and 100% industrial effluents applied as irrigation water. Effluents, initial soil, different parts of rice plants and post-harvest pot soil were analyzed for various elements, including heavy metals. Application of elevated levels of effluent contributed to increased heavy metals in pot soils and rice roots due to translocation effects, which were transferred to rice straw and grain. The results indicated that heavy metal toxicity may develop in soil because of contaminated effluent *** metals are not biodegradable, rather they accumulate in soils, and transfer of these metals from effluent to soil and plant cells was found to reduce the growth and development of rice plants and thereby contributed to lower yield. Moreover, a higher concentration of effluent caused heavy metal toxicity as well as reduction of growth and yield of rice, and in the long run a more aggravated situation may threaten human lives,which emphasizes the obligatory adoption of effluent treatment before its release to the environment, and regular monitoring by government agencies needs to be ensured.

关键词： Biomass Crop yield Heavy metal Industrial effluent Soil pollution

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HBsAg, HBcAg, and combined HBsAg/HBcAg-based therapeutic vaccines in treating chronic hepatitis B virus infection

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Hepatobiliary & Pancreatic Diseases International 2013年第4期12卷 363-369页

作者： Sheikh mohammad Fazle Akbar Mamun Al-Mahtab mohammad Helal uddin Md. Sakirul Islam Khan Department of Medical Sciences Toshiba General HospitalTokyo Japan Department of Hepatology Bangabandhu Sheikh Mujib Medical UniversityDhaka Bangladesh Clinical Research Organization Dhaka Bangladesh Laboratory of Animal Production Faculty of Agriculture Ehime UniversityMatsuyama Japan

BACKGROUND: As the host immunity is diminished in patients with chronic hepatitis B (CHB), different approaches have been used to up-regulate their immune responses to produce therapeutic effects. But, cytokines, growth factors and polyclonal immune modulators could not exhibit sufficient therapeutic effects in these patients. Immune therapy with HBV-related antigens (vaccine therapy) has been used in CHB patients. But there is a paucity of information about the design of HBV antigen-based immune therapy in these patients. DATA SOURCE: Preclinical and clinical studies on immune therapy with HBsAg-based vaccine, HBcAg and combination of HBsAg/HBcAg-based vaccines have been discussed. RESULTS: HBsAg-based prophylactic vaccine was used as an immune therapeutic agent in CHB patients; however, monotherapy with HBsAg-based immune therapy could not lead to sustained control of HBV replication and/or liver damages. HBsAg-based vaccine was used as a combination therapy with cytokines, growth factors, and antiviral drugs. HBsAg-based vaccine was also used for cell-based therapy. However, satisfactory therapeutic effects of HBsAg-based vaccine could not be documented in CHB patients. In the mean time, evidences have supported that HBcAg-specific immunity is endowed with antiviral and liver protecting capacities in CHB patients. Recent data concentrate on the clinical use of combined HBsAg- and HBcAg-based vaccines in CHB ***: Antigen-based immune therapy with HBV- related antigens may be an alternative method for the treatment of CHB patients but proper designs of antigens, types of adjuvants, dose of vaccinations, and routes of administration need further analyses for the development of an effective regimen of immune therapy against HBV.

关键词： chronic hepatitis B HBsAg vaccine HBsAg/HBcAg vaccine immune therapy therapeutic vaccines

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Germinant ZnO nanorods as a charge-selective layer in organic solar cells

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Journal of Materials Science & Technology 2020年第20期52卷 89-94页

作者： Kunsik An Jaehoon Kim mohammad Afsar uddin Seunghyun Rhee Hyeok Kim Kyung-Tae Kang Han Young Woo Changhee Lee Department of Electrical and Computer Engineering Seoul National UniversitySeoul 08826Republic of Korea Micro/Nano Process Group Korea Institute of Industrial Technology(KITECH)Sangnok-guAnsan-si 15588Republic of Korea Department of Chemistry College of ScienceKorea UniversitySeoul 02841Republic of Korea Department of Electrical Engineering Engineering Research Institute(ERI)Gyeongsang National UniversityJinju 52828Republic of Korea

A facile method was introduced and demonstrated to synthesize zinc oxide(ZnO) nanorods(NRs) as an electron transporting layer(ETL) for organic solar cells(OSCs).Hydrothermal synthesis of the NRs showed a constant growth rate of 5.5 nm min-1 from germination to sub-micrometer *** properties were characterized using scanning electron microscopy(SEM),transmission electron microscopy(TEM),absorption spectrophotometry and so *** on these measurements,the germinant growth mechanism and its corresponding orientation characteristics were *** an ETL of the OSCs,ZnO NRs enhance the charge extraction from the active layer due to their increased interfacial surface area,but there is an optimal length because of the shunt path formation and UV absorption of long ZnO *** a re sult,the OSC with the ZnO NRs as ETL shows power conversion efficiency(PCE) up to 6.2%.The J-V characteristics and incident photon-to-current conversion efficiency(IPCE) measurement also reveal that the efficiency enhancement is an assembly of individual results from optical,physical and electrical characteristic of the ZnO NRs.

关键词： ZnO nanorods Solar cells Self-assembly Oriented growth mechanism Hydrothermal synthesis

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