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Antimicrobial resistance pattern in ventilator-associated pneumonia in an intensive care unit of Babol, northern Iran

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Journal of Acute Disease 2018年第2期7卷 74-77页

作者： Mahmoud Sadeghi-Haddad-Zavareh Hadi Ahmadi Jouybari Mostafa Javanian Mehran Shokri Masomeh Bayani mohammad reza hasanjani roushan Arefeh Babazadeh Soheil Ebrahimpour Parviz Amri Maleh Infectious Diseases and Tropical Medicine Research Center Health Research InstituteBabol University of Medical SciencesBabolI.R.Iran Department of Anesthesiology School of MedicineBabol University of Medical SciencesBabolI.R.Iran

Objective:To investigate antibiotic resistance pattern of ventilator-assiated pneumonia (VAP) generating microorganisms,and quantitative culture and determining antibiotic ***:This cross sectional study was performed on 50 patients suffering from VAP in intensive care unit of Ayatollah Rouhani Hospital,Babol,Iran during *** was probable for them based on clinical signs and the criteria of Clinical Pulmonary Infection Score *** respiratory samples were given under bronchoalveolar lavage and quantitative culture was done on *** by microdilution method,minimal inhibitory concentration based on respective microorganisms,considering clinical pulmonary infection score were ***:From 50 investigated samples in this study,the most common microorganisms were Acinetobacter baumannii (***) (70%) then Pseudomonas aeruginosa (12%),Staphylococcus aureus (8%) and Klebsiella pneumonia (3%).In our study *** showed approximate 100% resistance to all antibiotics,in a way that *** resistance to imipenem and meropenem and piperacillin/tazobactam each was 97.1%.The most resistance of Pseudomonas aeruginosa was 66.7% to each cefepime and ceftazidime and clavulanate/*** aureus showed 75% resistance to nafcillin,cloxacillin and resistance in case of vancomycin was not ***:In current study,*** had the most prevalence among VAP and this species is resistant to most of *** ceftazidime,cefepime and clavulanate/ticarcillin,in treatment of the patients suffering VAP is not reasonable.

关键词： Antibacterial resistant Ventilator-associated pneumonia Intensive care unit

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