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Recent antibacterial agents from biomass derivatives:Characteristics and applications

Journal of Bioresources and Bioproducts 2024年第3期9卷 283-309页

作者： Nissa Nurfajrin Solihat Alif Faturahman Hidayat R.A.Ilyas Senthil muthu Kumar Thiagamani Nur Izyan Wan Azeele Fahriya Puspita Sari maya Ismayati mohammad Irfan Bakshi Zaharaddeen N.Garba m.Hazwan Hussin Witta Kartika Restu Wasrin Syafii Harits Atika Ariyanta Widya Fatriasari Research Center for Biomass and Bioproducts National Research and Innovation Agency(BRIN)Kawasan KST SoekarnoJl Raya Bogor KM 46 Cibinong Bogor 16911Indonesia Department of Bioproducts and Biosystems School of Chemical EngineeringAalto UniversityEspoo 16300Finland Department of Chemical Engineering Faculty of Chemical and Energy EngineeringUniversiti Teknologi MalaysiaJohor 81310Malaysia Centre for Advanced Composite materials Universiti Teknologi MalaysiaJohor 81310Malaysia Institute of Tropical Forestry and Forest Products Universiti Putra MalaysiaSerdang 43400Malaysia Centre of Excellence for Biomass Utilization Universiti Malaysia PerlisPerlis 02600Malaysia Department of mechanical Engineering Kalasalingam Academy of Research and EducationKrishnankoil 626126India Institute of Bioproduct Development(IBD) Universiti Teknologi MalaysiaJohor 81310Malaysia Department of Chemistry Ahmadu Bello UniversityZaria 810211Nigeria materials Technology Research Group(maTReC) School of Chemical SciencesUniversiti Sains MalaysiaMinden 11800Malaysia Research Center for Chemistry National Research and Innovation Agency(BRIN)Kawasan Puspiptek SerpongSouth Tangerang 15314Indonesia Department of Forest Products Faculty of Forestry and EnvironmentIPB UniversityBogor 16680Indonesia Department of Pharmacy Gunadarma UniversityDepok 16424Indonesia Research Collaboration Center of Biomass-Based Nano Cosmetic In collaboration with National Research and Innovation Agency(BRIN)SamarindaEast KalimantanIndonesia

Enhancing awareness of personal cleanliness and antibacterial resistance has intensified the antibacterial substance request on consumable products. Antibacterial agents that have been commercialized nowadays are produced from inorganic and non-renewable substances. This provides several drawbacks, particularly against health and environmental issues. Therefore, many scientists work on substituting fossil-fuel-based antibacterial agents with natural ones such as from biomass. Biomass derivatives, natural abundances of biopolymers in the world, amount to major compounds including polysaccharides (cellulose, hemicellulose, and chitosan) and polyphenol (tannin and lignin) substances which are capable to combat the growth of Gram-positive bacteria and Gram-negative bacteria. To date, no report focuses on a deep understanding of antibacterial properties derived from biomass and the internal and external factors effects. This work provides that gap because comprehensive knowledge is necessary before applying biomass to the products. The potency of biomass derivatives as antibacterial additives is also summarized. Basic knowledge of antibacterial characteristics to the application in products is highlighted in this review. Besides, the discussion about challenges and future perspectives is also delivered.

关键词： Antibacterial Application Biomass derivatives Challenge Future perspectives

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Dual-functional microneedle with programmatic regulation of macrophage for autoimmune psoriasis treatment

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Nano Research 2024年第8期17卷 7436-7448页

作者： Ze Qiang Zhao Bo Zhi Chen Jia Li Gan Yun Hao Feng Ling Liang Lingyun Yu Zi Yi Wang Samin Abbaszadeh mohammad-Ali Shahbazi Ruixing Yu Xin Dong Guo State Key Laboratory of Organic-Inorganic Composites Beijing University of Chemical TechnologyBeijing 100029China Beijing Laboratory of Biomedical materials College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029China China-Japan Friendship Hospital Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100029China Department of Dermatology China-Japan Friendship HospitalBeijing 100029China Department of Pharmaceutical Biomaterials School of PharmacyZanjan University of Medical SciencesZanjan 45139-56184Iran Department of Biomaterials and Biomedical Technology University Medical Center GroningenUniversity of GroningenAntonius Deusinglaan 19713 AV GroningenThe Netherlands W.J.Kolff Institute for Biomedical Engineering and materials Science University of GroningenAntonius Deusinglaan 19713 AV GroningenThe Netherlands

modulating the immune microenvironment to establish sustained positive feedback within immune pathways represents a promising avenue for the treatment of ***,the precise and efficient delivery of therapeutic systems to the subcutaneous basal layer to modulate immune disorders is a major challenge in the treatment of autoimmune *** this project,we introduce a dual-functional microneedle(DF-mN)designed to combine mNs with multiple release kinetics and immunotherapy,the programmed treatment is achieved through segmented design of the mN structure,realizing the unification of rapid and long-lasting treatment of autoimmune *** vivo imaging results showed that GelmA@m-CSF showed fluorescent signals after 5 days of delivery to subcutaneous tissues,whereas HA@IL-13 showed minimal fluorescent signals after 2 *** multistage release behavior of mNs and the diffusion mechanism of drugs were explained at the molecular level,in combination with coarse-grained molecular ***,DF-mN can successfully induce macrophage reprogramming in vitro and ameliorate overall symptoms in a psoriasis mice model,suggesting that it has the potential to be an effective strategy for the treatment of psoriasis and portends to be a transformative platform for the treatment of other autoimmune diseases.

关键词： microneedle psoriasis m2 macrophage immunoregulation

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AutomL: A systematic review on automated machine learning with neural architecture search

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Journal of Information and Intelligence 2024年第1期2卷 52-81页

作者： Imrus Salehin md.Shamiul islam Pritom Saha S.m.Noman Azra Tuni md.mehedi Hasan md.Abu Baten Department of Computer Engineering Dongseo University47 Jurye-roSasang-guBusan 47011Republic of Korea Department of Computer Science and Engineering Daffodil International UniversityDhaka 1216Bangladesh Department of Computer Science and Engineering Bangladesh University of Business and TechnologyDhaka 1216Bangladesh Faculty of Computer Science and Engineering Frankfurt University of Applied SciencesFrankfurt 60318Germany Department of Computer Science and Engineering University of Asia PacificDhaka 1205Bangladesh Department of Computer Science and Engineering Ahsanullah University of Science and TechnologyDhaka 1208Bangladesh Department of Computer Science and Engineering Northern University BangladeshDhaka 1215Bangladesh

AutomL(Automated machine Learning)is an emerging field that aims to automate the process of building machine learning *** emerged to increase productivity and efficiency by automating as much as possible the inefficient work that occurs while repeating this process whenever machine learning is *** particular,research has been conducted for a long time on technologies that can effectively develop high-quality models by minimizing the intervention of model developers in the process from data preprocessing to algorithm selection and *** this semantic review research,we summarize the data processing requirements for AutomL approaches and provide a detailed *** place greater emphasis on neural architecture search(NAS)as it currently represents a highly popular sub-topic within the field of *** methods use machine learning algorithms to search through a large space of possible architectures and find the one that performs best on a given *** provide a summary of the performance achieved by representative NAS algorithms on the CIFAR-10,CIFAR-100,ImageNet and wellknown benchmark ***,we delve into several noteworthy research directions in NAS methods including one/two-stage NAS,one-shot NAS and joint hyperparameter with architecture *** discussed how the search space size and complexity in NAS can vary depending on the specific problem being *** conclude,we examine several open problems(SOTA problems)within current AutomL methods that assure further investigation in future research.

关键词： AutomL Neural architecture search Advance machine learning Search space Hyperparameter optimization

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Influence of cerium ions on structure-dependent magnetic properties of Ba-Sr m-type hexaferrite nanocrystals

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Journal of Rare Earths 2024年第2期42卷 364-372,I0005页

作者： Ram A.Pawar Sunil m.Patange P.m.Dighe Sher Singh meena Abdullah GAl-Sehemi mehboobali Pannipara Santosh S.Jadhav Department of Physics ArtsCommerce and Science CollegeAhmednagar413711MaharashtraIndia Department of Physics Shri Krishna MahavidyalayaGunjotiDistOsmanabad413606MaharashtraIndia Padmashri Vikhe Patil College of Arts Science and CommercePravaranagarA/P.Loni(Kd)Tal.RahataDistAhmednagar413713MaharashtraIndia Solid State Physics Division Bhabha Atomic Research CentreMumbai400085MaharashtraIndia Department of Chemistry King Khalid UniversityAbha61413Saudi Arabia Department of Physics D.S.M's ArtsCommerce and Science CollegeJintur431509MaharashtraIndia

The present study is a systematic effort to investigate the structure-sensitive magnetic parameters of Ce^(3+) substituted Ba-Sr hexaferrite nanocrystals chemically formulated as Ba_(0.5)Sr_(0.5)Ce_(x)Fe_(12-x)O_(19) where x=0.0-0.2 with Δx=*** hexaferrite powders were prepared using the sol-gel self-ignition route and structurally characterized by means of powder X-ray diffraction and Fourier transform infrared *** creation of the m-type hexaferrite phase within the synthesized samples was revealed from the Rietveld refinement of the X-ray *** occurrence of a secondary phase of CeO_(2) was revealed within the hexaferrites for the substitution,x> *** refined X-ray diffraction data were utilized to compute the lattice parameters,X-ray density,and lattice parameter *** crystal structure plotted from the refined XRD data reveals the occupancy of the ions at different lattice *** XPS data of the hexaferrite were analyzed to confirm the oxidation states of the constituent *** nanocrystalline nature of the hexaferrites was revealed from the crystallite sizes calculated using Scherer's *** analysis of FTIR spectra confirms that only a fraction of Ce^(3+)accommodated in the lattice and the remaining Ce content reside in the form of the CeO_(2) *** morphology of the hexaferrites was analyzed from the FESEm profiles of the ferrite *** magnetic behavior study was performed by analyzing the Curie temperature,hysteresis loops,and hyperfine interactions by means of susceptibility,V.S.m,and mossbauer spectroscopy,*** hexaferrites with increasing coercivity,decreasing saturation magnetization,and decreasing Curie temperature are reported in the *** substituted Ce^(3+)ions inhibit the grain growth and create lattice imperfections giving rise to hexaferrites with tuned magnetic parameters suitable for different applications.

关键词： Ba-Sr hexaferrite Ce^(3+)substitution XPS Saturation magnetization Coercivity m?ssbauer spectroscopy

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The Effect of Injection Angle on mixing and Flame Holding in Supersonic Combustor

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Journal of Thermal Science 2002年第1期11卷 80-91页

作者： Shakil Ahmed mohammad Ali A. K. m. Sadrul islam Department of mechanical Engineering Bangladesh University of Engineering and Technology (BUET) Dhaka Bangladesh

A numerical study on mixing of hydrogen injected into a supersonic air stream has been performed by solving two-dimensional full Navier-Stokes equations. An explicit Harten-Yee Non-mUSCL modified-flux-type TVD scheme has been used to solve the system of equations, and a zero-equation algebraic turbulence model to calculate the eddy viscosity coefficient. The main objectives of this study are to increase the mixing efficiency and flame holding capability of a supersonic combustor. The performance of combustor has been investigated by varying the hydrogen injection angle made with the direction of air stream considering anti-clockwise direction as positive. The injector position from left boundary, backward-facing step height and the inlet width of air stream are kept constant. The results show that upstream of injector the mixing is dominated by recirculation and in downstream the mixing is dominated by mass concentration of hydrogen. Upstream recirculation is dominant for injecting angle 600 and 900 . Incorporating the various effects, perpendicular injection shows the maximum mixing efficiency and its large upstream recirculation region has a good flame holding capability.

关键词： scramjet engine TVD scheme backward-facing step supersonic mixing supersonic stream flame holding.

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Assessment the effect of Dapoxetine and/or Acetaminophen in rats;neurochemicals and oxidative stress biomarkers evaluation

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Brain Science Advances 2024年第1期10卷 57-71页

作者： Gehan S.Georgy Ibrahim m.Ibrahim Laila mohamed E.Amer Ebtehal mohammad F. Pharmacology Department Egyptian Drug Authority(EDA)Giza P.O.29Egypt molecular Drug Evaluation Department Egyptian Drug Authority(EDA)Giza P.O.29Egypt Histology Department Faculty of MedicineAl-Azhar UniversityDamietta P.O.11651Egypt

Dapoxetine is a newer anti-depressant that is used for severe forms of depression via selective serotonin reuptake inhibition *** aimed to evaluate the effect of different doses of dapoxetine lonely or with acetaminophen(AmP).Seven groups of albino rats were used where dapoxetine was administered orally at the doses of 3,5,and 8 mg/kg body weight for a period of 14 days in groups 2,4,and 6,***(67.5 mg/kg body weight)was co-administered with dapoxetine(3,5,and 8 mg/kg body weight)for 14 days in groups 3,5 and 7,*** in mid and high dose plus AmP increased body weight and hematological *** and rearing were declined with mid and high doses of dapoxetine+AmP,contrary to *** was decreased with high doses of dapoxetine+*** dose of dapoxetine+AmP induced lowering of serotonin and dopamine as well as increasing of *** derived neurotrophic factor was decreased in all *** stress biomarkers were augmented with high dose of dapoxetine+*** doses of dapoxetine and/or AmP induced loss of the Purkinje cell layer at *** high dose of dapoxetine+AmP denotes behavioral,histopathological and neurochemical alterations,even though no serotonin syndrome occurs.

关键词： acetaminophen dapoxetine neurotransmitters oxidative stress biomarkers

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Autophagy as a targeted therapeutic approach for skin cancer:Evaluating natural and synthetic molecular interventions

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Cancer Pathogenesis and Therapy 2024年第4期2卷 231-245页

作者： md.Liakot Ali Amdad Hossain Roky S.m.Asadul Karim Azad Abdul Halim Shaikat Jannatul Naima meem Emtiajul Hoque Abu mohammed Fuad Ahasan mohammed murshedul islam md.Saifur Rahaman Arif md.Saqline mostaq md.Zihad mahmud mohammad Nurul Amin mdAshiq mahmud Department of Pharmacy University of ChittagongChattogram 4331Bangladesh Pratyasha Health Biomedical Research Center Dhaka 1230Bangladesh Department of Pharmacy International Islamic University ChittagongChattogram 4318Bangladesh Department of Pharmacy Daffodil International UniversityDhaka 1216Bangladesh Department of Pharmacy BGC Trust University BangladeshChattogram 4381Bangladesh School of Basic Pharmaceutical and Toxicological Sciences College of PharmacyUniversity of Louisiana at MonroeMonroeLA 71209-0497USA Pioneer Dental College and Hospital Dhaka 1229Bangladesh

Skin cancer,a prevalent malignancy worldwide,poses significant health concerns owing to its increasing ***,a natural cellular process,is a pivotal event in skin cancer and has advantageous and detrimental *** duality has prompted extensive investigations into medical interventions targeting autophagy modulation for their substantial therapeutic *** systematic review aimed to investigate the relationship between skin cancer and autophagy and the contribution and mechanism of autophagy modulators in skin *** outlined the effectiveness and safety of targeting autophagy as a promising therapeutic strategy for the treatment of skin *** comprehensive review identified a diverse array of autophagy modulators with promising potential for the treatment of skin *** of these compounds demonstrates efficacy through distinct physiological mechanisms that have been elucidated in ***,findings from a literature search indicated that none of the natural,synthetic,or semisynthetic compounds exhibited notable adverse effects in either human or animal ***,this review offers novel mechanistic and therapeutic perspectives on the targeted modulation of autophagy in skin cancer.

关键词： Autophagy Skin cancer Autophagy inducers Autophagy inhibitors Nature-derived compounds Synthetic compounds

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microbial,immune and antioxidant responses of Nile tilapia with dietary nano-curcumin supplements under chronic low temperatures

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Aquaculture and Fisheries 2024年第1期9卷 57-65页

作者： mohammed F.El Basuini mohamed A.A.Zaki Abdelaziz m.El-Hais mohamed G.Elhanafy Emad H.El-Bilawy Amr I.Zaineldin mohamed F.A.Abdel-Aziz Ibrahim A.Abouelsaad Ibrahim TEl-Ratel Kumbukani mzengereza Ronick S.Shadrack islam I.Teiba Faculty of Agriculture Tanta UniversityTanta31527Egypt King Salman International University South Sinai46618Egypt Faculty of Agriculture Alexandria UniversityAlexandria21526Egypt Animal Health Research Institute(AHRI-DOKI) Agriculture Research CenterGiza12619Egypt Fish Rearing Lab. Aquaculture DivisionNational Institute of Oceanography and FisheriesAlexandria21556Egypt Horticulture Department Faculty of AgricultureDamanhour UniversityDamanhur22511Egypt Department of Poultry Production Faculty of AgricultureDamietta UniversityDamietta34517Egypt Laboratory of Aquatic Animal Nutrition Faculty of FisheriesKagoshima UniversityKagoshima890-0065Japan Department of Aquatic and Fisheries Science Mzuzu UniversityMzuzuPrivate Bag 201Malawi Faculty of Aquaculture and marine Fisheries Arish UniversityArish45516Egypt

A 56-day feeding period was performed to investigate the possible impacts of dietary nano curcumin(0,50,100,150,and 200 ppm)on the growth,nutrient utilization,non-specific immune parameters,antioxidants in Nile tilapia under chronic low temperature(21.02±0.11◦C).Fishes(n=225;Initial weight=4.39±0.08 g/fish)were randomly stocked at 15 fish/tank for five experimental groups in *** low-temperature circumstances,dietary curcumin in nano form showed no notable alteration in growth variable,nutrient efficiency,digestive enzymes efficiency,biometric indices,survival rates,and hematological ***,the serum of fishes with nano curcumin diets under low-temperature stress displayed higher total protein as well as lower glucose,cortisol,and total cholesterol compared with the control ***,fish fed nano curcumin diets displayed higher lysozyme and bactericidal activities compared to the control group and the best performance was found at dietary nano curcumin level of≥100 ***,groups fed the basal diet demonstrated the poorest antioxidant capacity,and the best superoxide dismutase(SOD)and glutathione peroxidase(GPx)existed in fish with nano curcumin diets while the best catalase(CAT)efficiency occurred at higher nano curcumin levels≥100 *** addition,higher counts of intestinal microbiota in terms of total bacterial count(TBC),total yeast and molds count(TYmC),and coliform were noticed in fish consumed the basal diet compared to groups fed on nano curcumin *** conclusion,incorporating nano curcumin at a level of≥100 mg/kg diet(particularly at 150 mg/kg)improved a non-specific immune response,antioxidant,and healthier gastrointestinal microbiota in Nile tilapia under chronic low-temperature stress.

关键词： Nano curcumin Gastrointestinal microbiota Antioxidants Non-specific immune responses Temperature stress

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Frequency-dependent viscoelasticity effects on the wave attenuation performance of multi-layered periodic foundations

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Applied mathematics and mechanics(English Edition) 2024年第3期45卷 407-424页

作者： m.SAFI m.VAKILIFARD m.J.mAHmOODI Faculty of Civil Water&Environmental EngineeringShahid Beheshti UniversityTehran ***Iran Faculty of mechanical and Energy Engineering Shahid Beheshti UniversityTehran ***Iran

In this paper,layered periodic foundations(LPFs)are numerically examined for their responses to longitudinal and transverse modes in the time and frequency *** different unit-cells,i.e.,2-layer,4-layer,and 6-layer unit-cells,comprising concrete/rubber,concrete/rubber/steel/rubber,and concrete/rubber/steel/rubber/lead/rubber materials,respectively,are taken into ***,the viscoelasticity behavior of the rubber is modeled with two factors,i.e.,a frequency-independent(FI)loss factor and a linear frequency-dependent(FD)loss *** the extraction of the complex dispersion curves and the identification of the band gaps(BGs),the simulations of wave transmission in the time and frequency domains are performed using the COmSOL *** parametric studies evaluate the effects of the rubber viscoelasticity models on the dispersion curves and the wave transmission for the longitudinal and transverse *** results show that considering the rubber viscoelasticity enhances the wave attenuation ***,the transverse-mode damping is more sensitive to the viscoelasticity model than its longitudinal *** 6-layer unit-cell LPF exhibits the lowest BG,ranging from 4.8 Hz to 6.5 Hz.

关键词： layered metamaterial periodic foundation complex dispersion curve wave transmission diagram

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Foliar Application of Cytokinin modulates Gas Exchange Features,Water Relation and Biochemical Responses to Improve Growth Performance of maize under Drought Stress

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Phyton-International Journal of Experimental Botany 2022年第3期91卷 633-649页

作者： m.Rafiqul islam m.Shahinur islam Nurunnaher Akter mohammed mohi-Ud-Din mohammad Golam mostofa Department of Agronomy Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Department of Crop Botany Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Department of Biochemistry and molecular Biology Bangabandhu Sheikh Mujibur Rahman Agricultural UniversityGazipur1706Bangladesh Institute of Genomics for Crop Abiotic Stress Tolerance Department of Plant and Soil ScienceTexas Tech UniversityLubbockTX 79409USA

Improvement of plant performance under drought stress is crucial to sustaining agricultural *** current study investigated the ameliorative effects of foliar-applied kinetin,an adenine-type cytokinin(CK),on growth and gas exchange parameters,water relations and biochemical attributes of maize plants under drought ***-day-old maize plants were subjected to drought by maintaining soil moisture content at 25%field capacity for 8 days followed by foliar application of kinetin at 0,75,150 and 225 mg L^(−1)(CK0,CK75,CK150 and CK225,respectively)to the plants for two-times at the 9-day *** revealed that drought stress markedly reduced stem diameter,dry weight,chlorophyll content,gas exchange parameters and water balance but increased proline,malondialdehyde and soluble sugar contents,electrolyte leakage and senescence in maize *** of exogenous CK remarkably improved maize performance by modulating growth,gas exchange-and water relation-related parameters in a dose-dependent manner under drought ***225 increased chlorophyll content(by 61.54%),relative water content(by 49.14%),net photosynthesis rate(by 39.94%)and transpiration rate(by 121.36%)and also delayed leaf senescence but decreased internal CO_(2)concentration(by 7.38%),water saturation deficit(by 40.40%)and water uptake capacity(by 42.49%)in both well-watered and droughtstressed ***,CK application considerably decreased electrolyte leakage,proline,malondialdehyde and soluble sugar levels in drought-stressed maize plants,as also supported by heatmap and cluster *** together,exogenous CK at proper concentration(225 mg L^(−1))successfully improved maize performance under drought conditions,thereby suggesting CK application as a useful approach to alleviate drought-induced adverse effects in maize plants,and perhaps in other important crop plants.

关键词： Cytokinin drought maize osmoprotection photosynthesis water-use-efficiency

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