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Antioxidant therapy in the management of acute,chronic and post-ERCP pancreatitis:A systematic review

World Journal of Gastroenterology 2009年第36期15卷 4481-4490页

作者： Seyed Sajad mohseni Salehi Monfared Hamed Vahidi Amir Hossein Abdolghaffari Shekoufeh Nikfar mohammad Abdollahi Endocrinology and Metabolism Research Centre Tehran University of Medical Sciences Student Scientific Research Center Tehran University of Medical Science Pharmaceutical Sciences Research Center Tehran University of Medical Sciences Food&Drug Affairs and Food&Drug Laboratory Research Center Ministry of Health&Medical Education Faculty of Pharmacy and Pharmaceutical Sciences Research Center and Endocrinology&Metabolism Research CentreTehran University of Medical Sciences

We systematically reviewed the clinical trials which recruited antioxidants in the therapy of pancreatitis and evaluated whether antioxidants improve the outcome of patients with pancreatitis. Electronic bibliographic databases were searched for any studies which investigated the use of antioxidants in the management of acute pancreatitis （AP） or chronic pancreatitis （CP） and in the prevention of post-endoscopic retrograde cholangio-pancreatography （post-ERCP） pancreatitis （PEP） up to February 2009. Twenty-two randomized, placebo-controlled, clinical trials met our criteria and were included in the review. Except for a cocktail of antioxidants which showed improvement in outcomes in three different clinical trials, the results of the administration of other antioxidants in both AP and CP clinical trials were incongruent and ***, antioxidant therapy including allopurinol and N-acetylcysteine failed to prevent the onset of PEP in almost all trials. In conclusion, the present data do not support a benefit of antioxidant therapy alone or in combination with conventional therapy in the management of AP, CP or PER Further double blind, randomized, placebo-controlled clinical trials with large sample size need to be conducted.

关键词： Antioxidant Post-endoscopic retrogradecholangio-pancreatography pancreatitis Oxidative stress,Therapy Acute pancreatitis Chronic pancreatitis

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Evaluation of protein Z plasma level in beta-thalassemia major patients in Ahvaz city in Iran

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Frontiers in Biology 2017年第6期12卷 442-447页

作者： mohammad Taha Jalali Abdorrahim Absalan alireza mohseni Gholam Abbas Kaydani Zeinab Deris Zayeri Department of Laboratory Sciences Hyperlipidemia Research Center Diabetes Research Center Jundishapur University of MedicalSciences Ahvaz Iran Shefa Neuroscience Research Center KhatamAlanbia Hospital Tehran Iran Blood Transfusion Research Center High Institute for Research and Education in Transfusion Medicine Tehran Iran Golestan Hospital Clinical Research Development Unit Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran

Thrombotic episodes occurred frequently in beta-thalassemia major (BTM) patients, leading to hypercoagulability of plasma. Protein Z (PZ) is a vitamin-K-dependent anti-coagulation factor that plays a role in the human homeostatic process. The objective of the current study is to investigate the distribution pattern of PZ plasma concentrations between BTM patients and the normal population in Ahvaz city, the center of Khuzestan province, southwest of Iran. Forty confirmed BTM patients and 40 healthy volunteers were evaluated for complete blood count (CBC) indices and PZ plasma levels. CBC samples were measured using an automated cell counter, and PZ was assayed with an immunoassay method. Statistical analysis was conducted using SPSS software. The ROC curve and binary logistic regression estimated the sensitivity, specificity, and Odd’s ratio for PZ measurement. The mean±SD of the PZ plasma level in normal individuals was 1.68±0.63 μg/mL, and in BTM patients, it was 1.10±0.52 μg/mL. This shows a significant reduction of PZ in BTM patients statistically (CI = 0.99; p<0.001). Further, the mean±SD of the PZ plasma levels in BTM patients who received washed red blood cells was not significantly different from that of patients undergoing packed red blood cell therapy (CI = 0.95; p = 0.320). The area under the curve (AUC) for PZ was 0.759 (p = 0.00). The cut-off value = 1.4 μg/mL of the PZ plasma level had at least 70% sensitivity and specificity in BTM patients. Several epidemiologic studies have shown thromboembolism episodes in BTM patients. In the current study, PZ was reduced significantly in BTMs. We noticed that BTMs have lower plasma PZ concentration might be predisposed to BTM.

关键词： major beta-thalassemia protein Z thrombosis immunoassay anti-coagulation factor

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Determination of Istanbul geoid using GNSS/levelling and valley cross levelling data

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Geodesy and Geodynamics 2020年第3期11卷 163-173页

作者： Müge Albayrak Mustafa TevfikÖzlüdemir mohammad mohseni Aref Kerem Halicioglu Geomatics Engineering Istanbul Technical UniversityIstanbulTurkey School of Earth Science The Ohio Stare UniversityColumbusOHUSA Institute of Geosciences Potsdam UniversityPotsdamGermany Institute of Mathematics Freie UniversitātBerlinGermany

The Istanbul GPS Triangulation Network(IGTN) and the Istanbul Levelling Network(ILN),established in2006,provide data for the determination of a local GNSS/levelling geoid *** networks’ measurements were done separately on both the Asian and European sides of the Bosphorus Strait in the vicinity of *** connect these regions for those networks,a Valley Cross Levelling(VCL) data set,acquired in 1986 and 2004,was *** use of this VCL data set was challenging in calculating the Istanbul geoid model,primarily because of its *** this study,this challenge was overcome through newly collected VCL data in 2010,allowing for the readjustment of the ILN and the newly collected VCL data *** Istanbul geoid model was computed using soft computing techniques including the adaptive-network-based fuzzy inference system(ANFIS) and the artificial neural networks(ANNs).The resulting Istanbul GNSS/levelling geoid model is shown to be more reliable when compared with the model computed using conventional interpolation techniques.

关键词： GNSS/Icvclling Geoid Valley cross levelling Soft computing techniques Interpolation techniques

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Mesenchymal stem cells therapy and COVID19:a narrative review

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Precision Medicine Research 2021年第3期3卷 18-22页

作者： Mohsen Ebrahimi ali Ahmadi Fatemeh mohseni mohammad Taha Saadati Rad Department of Medicine Golestan Universityof Medical SciencesGorganIran Department of Biological Sciences andTechnologies Islamic Azad UniversitySari BranchSariIran. Psychiatry and Behavioral Science center Addiction InstituteMazandaran University of Medical ScienceSariIran

At the end of 2019,a new type of coronavirus pneumonia broke out in China and swept the world,and the World Health Organization named it *** stem cells(MSCs)are cells with high differentiation potential and their ability to *** therapeutic effects of mesenchymal stem cells are mediated by the secretion of various agents,including conventional secretory proteins such as cytokines and growth factors,as well as *** injection in patients with COVID-19 was found to have potent anti-inflammatory activity of mesenchymal stem *** processes were evident from numerous beneficial outcomes,including an increase in peripheral lymphocyte counts,a decrease in C-reactive protein,and a decrease in active cytokine-secreting immune cells in the circulating blood for 3 to 6 *** is suggested that due to the favorable results of studies in this field,more studies be done on this treatment method.

关键词： COVID19 Mesenchymal stem cells(MSCs) Pneumonia

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Sumac (<i>Rhus coriaria</i>L.): Scolicidal Activity on Hydatid Cyst Protoscolices

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Surgical Science 2012年第9期3卷 452-456页

作者： mohammad Moazeni Maryam mohseni Department of Pathobiology School of Veterinary Medicine Shiraz University Shiraz Iran

Background: Few anthelmintics are available for the treatment of hydatid disease caused by the parasite Echinococcus granulosus. The appearance of resistance to synthetic anthelmintics and the adverse side effects of chemical drugs, stimulated the research of alternatives, such as medicinal plants. In the present study, the scolicidal effect of methanolic extract of sumac (Rhus coriaria) was investigated. Methods: Protoscolices were aseptically collected from sheep livers containing hydatid cysts. Three concentrations of sumac extract (10, 30 and 50 mg/mL) were used for 10, 20 and 30 min. Viability of protoscolices was confirmed by 0.1% eosin staining. Results: While the rate of dead protoscolices was 16.93% in the ontrol group, when protoscolices were exposed to sumac extract at the concentration of 10 mg/mL , the rate of dead protoscolices increased to 94.13%, 97.67% and 100% after 10, 20 and 30 minutes, respectively. The mortality rate of protoscolices increased to 98.89%, and 100% when they were exposed to 30 mg/mL concentration of sumac extract for 10 and 20 minutes respectively. One hundred percent mortality rate was observed at concentration of 50 mg/mL after 10 min of exposure. Conclusions: This in vitro study showed that methanolic extract of *** may be considered as an effective natural scolicidal agent.

关键词： Hydatid Cyst Scolicidal Methanolic Extract Sumac Rhus Coriaria

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Applying XDEM to Analyze the Heat-up Process of Woody Biomass on a Backward Acting Grate

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Journal of Energy and Power Engineering 2017年第8期11卷 517-527页

作者： mohammad mohseni Bernhard Peters Algis Dziugys Faculty of Science University of Luxembourg rue Coudenhove-Kalergi L-1359 Luxembourg Lithuanian Energy Institute (LEI) Breslaujos str. 3 Kaunas LT-44403 Lithuania

The objective of this study is analysis of heat-up process of wet woody particles on a backward acting grate including dynamics motion investigation by implementing XDEM （extended discrete element method） as a novel approach. In this method, the particles are resolved as the discrete phase （individual elements） coupled via heat, mass and momentum transfer to the continuous gas phase. The temperature of particulates along the backward acting grate is investigated by evaluating effects of operating parameters such as bar amplitude and period. Furthermore, the bar motion has effects largely on the heat-up process of the packed bed on the backward acting grate which is considered here as well. In other words, motion of particles caused by bar motion influences the heat transfer of particles and totally the packed bed. In fact, the particles＇ heat-up is performed by a radiative heat flux facing the packed bed surface so that heat transfer of particles as radiation and conduction with surrounding particles is taken into account in addition to convection heat transfer between particles and surrounding gas phase.

关键词： XDEM backward acting grate biomass modelling heat-up.

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Effect of Timing of Circumcision on Sexual Satisfaction and Function

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Open Journal of Urology 2011年第1期1卷 8-10页

作者： Seyed Reza Hosseini mohammad Ghasem mohseni 不详

Objectives: Male circumcision is a commonly-performed surgical procedure in the world. Currently, no consensus exists about the role of the foreskin or the effect circumcision on sexual satisfaction. All previous studies have evaluated the effect of adult circumcision on sexual function. In this study, we responded to “Does circumcision timing have different effects on sexual function?” Methods: Based on circumcision timing (receiving circumcision in less than 18 year olds or older than 18 year olds), the participants were divided into two groups. The following data and measurements were investigated: IIEF-5 score, sexual satisfaction, sexual activity [number of sexual attempt/week] and ability to achieve or maintain an erection. Results: Two hundred and fifty cases including 125 men were investigated in each group. The baseline demographic (age, marital status, education, smoking) was similar in the 2 groups. No statistically significant differences were seen regarding their sexual satisfaction (P = 0.65), sexual activity [number of sexual attempt/week] (P = 0.74), ability to achieve or maintain an erection (P = 0.44), (P = 0.9). The total mean IIEF-5 score was 24.21 +/- 1.94 and 22.23 +/- 1.12 in groups 1 and 2, respectively (p = 0.5). Conclusion: We concluded that the age at which the circumcision is preformed has no effect on the degree of sexual function and satisfaction.

关键词： Circumcision Timing Sexual Function

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Experts’ perspectives on the application of public-private partnership policy in prevention of road traffic injuries

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Chinese Journal of Traumatology 2020年第3期23卷 152-158页

作者： Saber Azami-Aghdash Homayoun Sadeghi-Bazargani mohammad Saadati mohammad mohseni Hojatolah Gharaee Tabriz Health Services Management Research Center Health Management and Safety Promotion Research InstituteTabriz University of Medical SciencesTabrizIran Road Traffic Injury Research Center Tabriz University of Medical SciencesTabrizIran Health Management and Economics Research Center Iran University of Medical SciencesTehranIran Health Center of Hamadan City Hamadan University of Medical ScienceHamadanIran

Purpose: Successful application experiences on public-private partnership (PPP) in different countries, suggest that PPP could be an option in road traffic injury (RTI) prevention. The present study aims at investigating the applicability of PPP policy in RTI prevention in Iran based on the experts’ ***: This is a qualitative study with grounded theory approach which has been conducted in Tabriz University of Medical Sciences, Iran in 2018. The participants were 22 experts in the field of RTIs selected using purposive sampling method. Data were collected by semi-structured interviews and analyzed with content-analysis ***: The results were classified under 5 main themes (applicability, scopes and services, challenges, advantages, and strategies) for applying PPP policy and 37 sub-themes. Due to the prevalence of RTIs, the present challenges in public sector, existence of qualified private sector, and successful experiences in other areas, there are opportunities for private sector partnership in prevention of RTIs. Private sector could participate in different scopes and services regarding RTI prevention, including road construction and maintenance, maintenance and provision of vehicles safety and public education. The main challenges including legislation issues, ambiguities in collaboration, political and organizational unsustain-ability, government’s financial hardship and lack of experienced experts in the field of RTI. However, there are significant advantages including high efficiency in program implementation, covering the weaknesses of public sector, effective and efficient management on application of PPP in RTI prevention. The strategies include identifying and prioritizing the assignable activities, identifying the qualified private sector, developing PPP policies and legal frameworks, creating a common language between public and private parties, trying to meet the expectations of the private sector by public sector, developin

关键词： Road traffic injuries Experts'perspectives Public-private partnership Injury prevention

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Waveform Design for Cognitive Radar with Deterministic Extended Targets in the Presence of Clutter

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International Journal of Communications, Network and System Sciences 2016年第6期9卷 250-268页

作者： Vahid Karimi Reza mohseni Yaser Norouzi mohammad Javad Dehghani Department of Electrical Engineering Shiraz University of Technology Shiraz Iran Department of Electrical Engineering Amirkabir University of Technology Tehran Iran

Adjusting radar transmitted waveform to its environment is one of the most important roles in cognitive radar;having the capability of updating transmitted waveforms in different applications is a key point. It has been shown in many studies that if the waveform is designed according to the target and clutter characteristics, the detection performance will improve significantly. The uncertainty of the target radar signatures decreases via maximizing MI and the probability of extended target detection is increases via maximizing SNR. In this paper, a waveform design approach based on maximizing both SNR and MI and with regard to target and clutter shape is presented. The detection performance for proposed waveform is compared with previous proposed waveforms. The present paper compares different scenarios of target and clutter and using the probability of detection as a cost function to investigate the advantages and disadvantages of each waveform in different scenarios which are mainly discussed in this text. The desired waveform for cognitive radar is selected based on simultaneously making compromises between SNR and MI, which plays an important role in cognitive radar systems and based on the assumption addressed in the text, the best waveform transmitted into the environment.

关键词： Signal to Noise Ratio Mutual Information Cognitive Radar Deterministic Extended Target Clutter

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Analysis of Nosocomial Infections in Selected Teaching Hospitals, Qazvin, Iran

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Health 2014年第18期6卷 2425-2432页

作者： Fereshteh Farzianpour Ahad Bakhtiari Mohsen mohammadi Omid Khosravizadeh Hoda Mossavi mohammad mohseni mohammad Mahboubi Health Care Management Department of Health Management & Economic School of Public Health Tehran University of Medical Sciences Tehran Iran Healthcare Management School of Public Health Tehran University of Medical Sciences Tehran Iran Healthcare Management Kermanshah University of Medical Sciences Kermanshah Iran Healthcare Management Health Management and Economics Research Center Iran University of Medical Sciences Tehran Iran Healthcare Management Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran Abadan School of Medical Sciences Abadan Iran

Introduction: Hospital infections prolong patient hospitalization, necessitate additional treatment, increase mortality rate, raise hospital expenses, and even reduce the level of health in the society. The purpose of this research was to study hospital infections in selected hospitals of Qazvin. Methods and Materials: This was an analytic-cross-sectional study. The research population consisted of 25,628 hospitalized patients in the first eight months of 2012 in three selected hospitals of the Qazvin Province. The algorithm of reporting hospital infections, the National Program of Controlling Hospital Infections, and 223 patient files hospitalized due to hospital-acquired infections were used to collect information. The collected information was analyzed using the SPSS V. 17 software;the descriptive statistics was used to analyze the qualitative variables;and the descriptive statistics together with chi-square and t-test were employed for the quantitative variables. Results: The ICU units had the most cases of hospital infections. Respiratory pneumonia and urinary infections topped the list of hospital infections. The most invasive treatments carried out on patients with hospital infections were surgery, urinary catheter, and venous catheter, respectively. More than 50 percent of patients with hospital infections were hospitalized for 2 to 21 days. Results and Conclusions: Because of the high rate of hospital infections, especially in the ICU ward, authorities must give top priority in their plans to designing suitable educational programs to inform hospital staff and patients of hospital infections and to provide suitable resources for dealing with this problem.

关键词： Nosocomial Infections Teaching Hospitals

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