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Breast cancer therapy by laser-induced Coulomb explosion of gold nanoparticles

Chinese Journal of Cancer Research 2013年第6期25卷 756-761页

作者： Muhammad Gul Bahar Ashiq mohammad alam saeed Bashir Ahmad Tahir Noorddin Ibrahim Muhammad Nadeem Physics Department Universiti Teknologi Malaysia Department of Electrical and Computer Engineering McMaster University National Defense University of Malaysia

Objective： Laser-induced Coulomb explosion of gold nanoparticles for breast cancer has been studied by nanophotolysis technique. This study aimed to investigate whether laser-induced bubble formation due to Coulomb explosion can provide an effective approach for selective damage of breast cancer with gold nanoparticles. Method： Numerical method involves laser-induced Coulomb explosion of gold nanoparticles. Different parameters related to nanophotolysis such as laser fluence, tumor depth, cluster radius, laser pulse duration, and bubble formation is studied numerically. Numerical simulation was performed using Mat lab. Results： The gold nanopartieles of 10, 20, 30, 40, and 50 nm in radius could penetrate into tumor 1.14, 1.155, 1.189, 1.20 and 1.22 cm in depth respectively. The maximum penetration depth in tumor could be obtained with nanoparticles of 50 nm radius. Short laser pulse of 40 ns with nanoparticles of 10 nm radius could penetrate into tumor 1.14 cm in depth. Bubbles with a radius of 9 pm could effectively kill breast cancer cells without damaging healthy ones. The bubble radius increased from 4 to 9 lam with an increase in pulse duration in the range of 10 to 30 ns. Conclusions： Gold nanoparticles with increasing radius and bubble formation for selective damage of breast cancer cells are successfully probed. The present calculated results are compared with other experimental findings, and good correlation is found between the present work and previous experimental values. It was demonstrated that bubble formation in tumor may further increase the efficacy of breast cancer treatment.

关键词： Gold nanoparticles tumor depth nanophotolysis bubble formation breast cancer

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Implications of electrode modifications in aqueous organic redox flow batteries

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Journal of Energy Chemistry 2024年第8期95卷 499-510,I0011页

作者： Zahid Manzoor Bhat mohammad Furquan Muhammad Aurang Zeb Gul Sial Umair alam Atif saeed Alzahrani mohammad Qamar Interdisciplinary Research Center for Hydrogen Technologies and Carbon Management(IRC-HTCM) King Fahd University of Petroleum&Minerals(KFUPM)Dhahran 31261Saudi Arabia Department of Materials Science and Engineering King Fahd University of Petroleum and MineralsDhahran 31261Saudi Arabia Interdisciplinary Research Center for Sustainable Energy Systems(IRC-SES) King Fahd University of Petroleum and MineralsDhahran 31261Saudi Arabia

Aqueous organic redox flow batteries(RFBs)exhibit favorable characteristics,such as tunability,multielectron transfer capability,and stability of the redox active molecules utilized as anolytes and catholytes,making them very viable contenders for large-scale grid storage *** attention has been paid on the development of efficient redox-active molecules and their performance optimization through chemical substitutions at various places on the backbone as part of the pursuit for high-performance *** the fact that electrodes are vital to optimal performance,they have not garnered significant *** research has been conducted on the effects of electrode modifications to improve the performance of *** primary emphasis has been given on the impact of electrode engineering to augment the efficiency of aqueous organic *** overview of electron transfer at the electrode-electrolyte interface is *** implications of electrode modification on the performance of redox flow batteries,with a particular focus on the anodic and cathodic half-cells separately,are then *** each section,significant discrepancies surrounding the effects of electrode engineering are thoroughly examined and ***,we have presented a comprehensive assessment along with our perspectives on the future trajectory.

关键词： Redox flow batteries Electrode modification Organic redox molecules Outer sphere and inner sphere

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Time-dependent effects in transient liquid phase bonding of 304L and Cp-Ti using an Ag-Cu interlayer

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Journal of Central South University 2024年第7期31卷 2237-2255页

作者： saeed VAZIRIAN mohammad MOSHKBAR BAKHSHAYESH Ali FARZADI Department of Materials and Metallurgical Engineering Amirkabir University of Technology(Tehran Polytechnic)Tehran 15916-34311Iran

One of the challenges for bimetal manufacturing is the joining ***,transient liquid phase(TLP)bonding was performed between 304L stainless steel and Cp-Ti using an Ag-Cu interlayer with a thickness of 75μm for bonding time of 20,40,60,and 90 *** bonding temperature of 860℃ was considered,which is under the β transus temperature of *** TLP bonding,various intermetallic compounds(IMCs),including Ti_(5)Cr_(7)Fe_(17),(Cr,Fe)_(2)Ti,Ti(Cu,Fe),Ti_(2)(Cu,Ag),and Ti_(2)Cu from 304L toward Cp-Ti formed in the ***,on the one side,with the increase in time,further diffusion of elements decreases the blocky IMCs such as Ti_(5)Cr_(7)Fe_(17),(Cr,Fe)_(2)Ti,Ti(Cu,Fe)in the 304L diffusion-affected zone(DAZ)and reaction zone,and on the other side,Ti_(2)(Cu,Ag)IMC transformed into fine morphology toward Cp-Ti *** microhardness test also demonstrated that the(Cr,Fe)_(2)Ti+Ti_(5)Cr_(7)Fe_(17) IMCs in the DAZ on the side of 304L have a hardness value of HV 564,making it the hardest *** maximum and minimum shear strength values are equal to 78.84 and 29.0 MPa,*** cleavage pattern dominated fracture surfaces due to the formation of brittle phases in dissimilar joints.

关键词： diffusion brazing transient liquid phase bonding dissimilar material joints microstructural evolution mechanical properties grade 2 titanium

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Numerical investigation of supercontinuum generation and optical frequency combs in Si N-based PCF with high nonlinear coefficient

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Optoelectronics Letters 2024年第3期20卷 163-170页

作者： mohammad Reza Alizadeh Mahmood Seifouri saeed Olyaee Faculty of Electrical Engineering Shahid Rajaee Teacher Training UniversityTehranIran Nano-photonics and Optoelectronics Research Laboratory(NORLab) Shahid Rajaee Teacher Training UniversityTehranIran

In this paper, a photonic crystal fiber(PCF) with a dispersion-engineered and high nonlinear coefficient has been designed for supercontinuum generation(SCG) and frequency comb generation(FCG). The proposed PCF has a Si_(3)N_(4) rod in the core. This rod provides more optical confinement in the core by increasing the refractive index of the core. This high confinement reduces the effective mode area of PCF and thus increases the nonlinear coefficient.

关键词： optical fiber nonlinear

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Studying the effect of surfactant assisted low-salinity water flooding on clay-rich sandstones

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Petroleum 2024年第2期10卷 306-318页

作者： saeed Khezerloo-ye Aghdam Alireza Kazemi mohammad Ahmadi Department of Petroleum Engineering Amirkabir University of Technology (AUT) Department of Petroleum and Chemical Engineering College of Engineering Sultan Qaboos University

Sandstone reservoirs often contain clay particles that can cause damage and reduce permeability during low-salinity water flooding. In this study, the effect of surfactants on fine migration in clay-rich sandstones and its impact on oil recovery was ***, the impact of surfactants on interparticle forces in fine-matrix, fine-fine, and oil-matrix systems was modeled. The results showed that both CTAB(cetyltrimethyl ammonium bromide) and QS(quillaja saponin) cause EDL compaction, weakening the repulsive forces. However, SDS(sodium dodecyl sulfate)and TX(triton X-100) do not affect the EDL. Next, the effect of surfactants on IFT reduction and wettability alteration was experimentally investigated. All surfactants reduced IFT due to the surface excessive concentration mechanism. The wettability alteration experiment illustrated that although QS and CTAB compact EDL around oil and matrix particles leading to attraction force augmentation, they both alter wettability through adsorption on matrix and carboxylic groups present in crude oil, *** aqueous solutions were then injected into various clay-rich sandstone sanpacks, which resulted in increased oil recovery. However, the mechanisms leading to enhanced oil recovery variedby surfactant type. CTAB increased recovery by 10% through IFT reduction and wettability alteration, while SDS and TX increased recovery by 12% and 9%, respectively, through wettability alteration and extreme fine migration. In contrast, partial fine migration in the QS flooding experiment reached a recovery increase of 18%. Permeability trends through experiments were also recorded. During CTAB injection,permeability did not reduce, while QS aqueous solution reduced rock permeability to 5 m D. SDS and TX reduced the magnitude of permeability to 2 m *** conclusion, this study demonstrates that surfactants can effectively improve oil recovery in clay-rich sandstones by altering the interparticle forces, reducing IFT, a

关键词： Surfactant flooding Smart water Fine migration Recovery factor

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Stratigraphy of the Alveolina elliptica group from the Middle Eocene of Iran:Calibration with calcareous nannofossils biozones and description of Alveolina ozcani n. sp.

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Journal of Palaeogeography 2024年第1期13卷 54-79页

作者： Mehdi Hadi Lorenzo Consorti Ali Bahrami mohammad Parandavar saeed Khorramdel Department of Geology Faculty of SciencesUniversity of IsfahanIsfahanIran Institute of Marine Sciences(ISMAR-CNR) Area Science ParkBasovizza34149 TriesteItaly National Iranian Oil Company Exploration DirectorateSheikh Bahaei SquareTehranIran Department of Geology Faculty of ScienceFerdowsi University of MashhadMashhadIran

Precise taxonomy and the chronostratigraphic calibration of the Middle Eocene Alveolina from Central Iran is here undertaken from the Chah-Talkh section of the southern Sabzevar region(Central Iran). We have identified Alveolina kieli, Alveolina stercusmuris and Alveolina nuttalli along with the new species Alveolina ozcani n. sp. that we include into the Alveolina elliptica group. We have also found Nummulites uroniensis, Nummulites obesus and Nummulites cf. verneuili and associated calcareous nannofossils that look reliable to make thoughtful correlations with the Shallow Benthic Zones(SBZ). The foraminiferal biostratigraphy suggests an assignment to the upper part of the lower Lutetian-lower part of the middle Lutetian,SBZ13(Middle Eocene), further strengthened through the identification of the calcareous nannofossil NP14b-NP15b or CNE8-CNE10 biozones, providing a solid correlation with the global stratigraphic standards.

关键词： Alveolina Calcareous nannofossil Central neo-tethys Central Iran Middle Eocene Biostratigraphy

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Bulk-boundary and RPS thermodynamics from topology perspective

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Chinese Physics C 2024年第9期48卷 248-257页

作者： Jafar Sadeghi mohammad Reza Alipour saeed Noori Gashti mohammad Ali S.Afshar Department of Physics Faculty of Basic Sciences University of Mazandaran School of Physics Damghan University

In this study,we investigate the bulk-boundary and restricted phase space（RPS） thermodynamics of Rissner-Nordstrom（R-N） AdS and 6-dimensional charged Gauss-Bonnet AdS black ***,we examine the topological characteristics of the considered black holes and compare them with the results of extended *** determine that the topological behavior of the bulk-boundary thermodynamics is the same as that of the extended thermodynamics,whereas the RPS thermodynamics exhibits a distinct ***,we demonstrate that within the RPS formalism,there is only one critical point with a topological charge of +1（Q_t=+1）.Moreover,in the RPS formalism,the inclusion of higher-derivative curvature terms in the form of GaussBonnet gravity does not alter the topological classification of critical points in charged AdS black holes.

关键词： bulk-boundary restricted phase space thermodynamics topological charge

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Electrospun Aloe Vera Extract Loaded Polycaprolactone Scaffold for Biomedical Applications:A Promising Candidate for Corneal Stromal Regeneration

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Journal of Bionic Engineering 2024年第4期21卷 1949-1959页

作者： Amin Orash Mahmoud Salehi mohammad Rafienia Narsimha Mamidi saeed Heidari Keshel Alireza Baradaran-Rafii Department of Chemistry and Nanotechnology School of Engineering and ScienceTecnologico de MonterreyMonterreyNuevo Leon64849Mexico Biosensor Research Center Isfahan University of Medical SciencesIsfahan81746-73461Iran Wisconsin Center for NanoBioSystems School of PharmacyUniversity of Wisconsin-MadisonMadisonWisconsin53705USA Medical Nanotechnology Research Center Shahid Beheshti University of Medical SciencesTehran19857-17443Iran Department of Ophthalmology Ophthalmic Research CenterLabbafinejad Medical CenterShahid Beheshti University of Medical SciencesTehran19395-4631Iran Department of Ophthalmology Morsani College of MedicineUniversity of South FloridaTampaFL33612USA Department of Tissue Engineering and Applied Cell Science School of Advanced Technologies in MedicineShahid Beheshti University of Medical SciencesTehran19857-17443Iran

Corneal diseases,the second leading cause of global vision loss affecting over 10.5 million people,underscores the unmet demand for corneal tissue *** the scarcity of fresh donor corneas and the associated risks of immune rejection,corneal tissue engineering becomes *** nanofibrous scaffolds that mimic the natural corneal structure is crucial for creating transparent and mechanically robust corneal equivalents in tissue ***,Aloe Vera Extract(AVE)/Polycaprolactone(PCL)nanofibrous scaffolds were primed using *** electrospun AVE/PCL fibers exhibit a smooth,bead-free morphology with a mean diameter of approximately 340±95 nm and appropriate light *** measurements reveal Young’s modulus and ultimate tensile strength values of around 3.34 MPa and 4.58 MPa,respectively,within the range of stromal *** addition,cell viability of AVE/PCL fibers was measured against Human Stromal Keratocyte Cells(HSKCs),and improved cell viability was *** cell-fiber interactions were investigated using scanning electron *** conclusion,the incorporation of Aloe Vera Extract enhances the mechanical,optical,hydrophilic,and biological properties of PCL fibers,positioning PCL/AVE fiber scaffolds as promising candidates for corneal stromal regeneration.

关键词： Corneal stromal regeneration Aloe vera extract Polycaprolactone Electrospinning

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Temperature-jump tensile tests to induce optimized TRIP/TWIP effect in a metastable austenitic stainless steel

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International Journal of Minerals,Metallurgy and Materials 2024年第9期31卷 2025-2036页

作者： mohammad Javad Sohrabi Hamed Mirzadeh saeed Sadeghpour Abdol Reza Geranmayeh Reza Mahmudi School of Metallurgy and Materials Engineering College of EngineeringUniversity of Tehran14395-515TehranIran Centre for Advanced Steels Research Materials and Mechanical EngineeringUniversity of Oulu90014 OuluFinland

In the present work,plastic deformation mechanisms were initially tailored by adjusting the deformation temperature in the range of 0 to 200℃ in AISI 304L austenitic stainless steel,aiming to optimize the strength-ductility *** was shown that the combined twinning-induced plasticity(TWIP)/transformation-induced plasticity(TRIP)effects and a wider strain range for the TRIP effect up to higher strains by adjusting the deformation temperature are good strategies to improve the strength-ductility synergy of this metastable stainless *** this regard,by consideration of the observed temperature-dependency of plastic deformation,the controlled sequence of TWIP and TRIP effects for archiving superior strength-ductility trade-off was intended by the pre-designed temperature jump tensile ***,the optimum tensile toughness of 846 MJ/m^(3) and total elongation to 133% were obtained by this strategy via exploiting the advantages of the TWIP effect at 100℃ and the TRIP effect at 25℃ at the later stages of the ***,a deformation-temperature-transformation(DTT)diagram was developed for this metastable ***,based on work-hardening analysis,it was found that the main phenomenon constraining further improvement in the ductility and strengthening was the yielding of the deformation-induced α′-martensite.

关键词： metastable stainless steels transformation-induced plasticity twinning-induced plasticity stacking fault energy mechanical properties

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Interplay between temperature-dependent strengthening mechanisms and mechanical stability in high-performance austenitic stainless steels

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International Journal of Minerals,Metallurgy and Materials 2024年第10期31卷 2182-2188页

作者： mohammad Javad Sohrabi Hamed Mirzadeh saeed Sadeghpour Milad Zolfipour Aghdam Abdol Reza Geranmayeh Reza Mahmudi School of Metallurgy and Materials Engineering College of EngineeringUniversity of Tehran14395-515 TehranIran Centre for Advanced Steels Research Materials and Mechanical EngineeringUniversity of Oulu90014 OuluFinland Department of Mechanical Engineering College of EngineeringUniversity of Tehran14395-515 TehranIran

The effects of deformation temperature on the transformation-induced plasticity(TRIP)-aided 304L,twinning-induced plasti-city(TWIP)-assisted 316L,and highly alloyed stable 904L austenitic stainless steels were compared for the first time to tune the mechan-ical properties,strengthening mechanisms,and strength-ductility *** this purpose,the scanning electron microscopy(SEM),electron backscattered diffraction(EBSD),X-ray diffraction(XRD),tensile testing,work-hardening analysis,and thermodynamics calcu-lations were *** induced plasticity effects led to a high temperature-dependency of work-hardening behavior in the 304L and 316L stainless *** the deformation temperature increased,the metastable 304L stainless steel showed the sequence of TRIP,TWIP,and weakening of the induced plasticity mechanism;while the disappearance of the TWIP effect in the 316L stainless steel was also ***,the solid-solution strengthening in the 904L superaustenitic stainless steel maintained the tensile properties over a wide temper-ature range,surpassing the performance of 304L and 316L stainless *** this regard,the dependency of the total elongation on the de-formation temperature was less pronounced for the 904L alloy due to the absence of additional plasticity *** results re-vealed the importance of solid-solution strengthening and the associated high friction stress for superior mechanical behavior over a wide temperature range.

关键词： austenitic stainless steels mechanical behavior stacking fault energy metastability mechanical twinning

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