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Antifouling evaluation of extracts from Red Sea soft corals against primary biofilm and biofouling

Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 991-997页

作者： Yosry abdel Aziz Soliman Ahmed Mohammed Brahim Ahmed Hussein Moustafa Mohamed abdel Fattah Hamed Marine Chemistry Lab. Marine Environment DivisionNational Institute of Oceanography and FisheriesSuezEgypt Department of Chemistry Faculty of ScienceZagazig UniversityZagazigEgypt

Objectives: To evaluate antifouling property of extracts from Red Sea soft corals against primary biofilm and biofouling.Methods: Seven species of soft corals Sarcophyton glaucum(a), Sinularia compressa,Sinularia cruciata(a), Heteroxenia fuscescens(a), Sarcophyton glaucum(b), Heteroxenia fuscescens(b) and Sinularia cruciata(b) were chosen to test their extracts as antibacterial and antifouling agents in Eastern Harbour of Alexandria, Mediterranean Sea.Bioactive compounds of soft corals were extracted by using methanol and concentrated under vacuum. The residues of extracts were mixed in formulation of inert paint which consisted of rosin, chlorinated rubber and ferrous oxide against micro and macro fouling organisms. The formulated paints were then applied on PVC panels twice by brush,hanged in a steel frame and immersed in Eastern Harbour of Alexandria Mediterranean Sea followed by visual inspection and photographic recordings.Results: After 185 days of immersion in seawater, the antifouling results agreed with the antibacterial results where extracts of Sinularia compressa and Heteroxenia fuscescens(b) gave the best activity against marine fouling tubeworms and barnacles. The inhibition activity was correlated with the major functional groups(hydroxyl, amino, carbonyl,aliphatic(fatty acids), C]C of alkene or aromatic rings and CeC l of aryl halides) of the extracts.Conclusions: The strong antifouling activity makes them promising candidates for new antifouling additives. After the screening and application of natural organic compounds from soft corals, marine organisms show activity against micro and macro fouling organisms.

关键词： Antibacterial Antifouling Paints Seawater Marine Organisms

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Behavior of raft on settlement reducing piles:Experimental model study

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Journal of Rock Mechanics and Geotechnical Engineering 2013年第5期5卷 389-399页

作者： Basuony El-Garhy Ahmed abdel Galil abdel-fattah Youssef mohamed Abo Raia Civil Engineering Department Faculty of Engineering Minufiya University

An experimental program is conducted on model piled rafts in sand soil.The experimental program is aimed to investigate the behavior of raft on settlement reducing piles.The testing program includes tests on models of single pile,unpiled rafts and rafts on 1,4,9,or 16 piles.The model piles beneath the rafts are closed ended displacement piles installed by driving.Three lengths of piles are used in the experiments to represent slenderness ratio,L/D,of 20,30 and 50,respectively.The dimensions of the model rafts are 30 cm×30 cm with different thickness of 0.5 cm,1.0 cm or 1.5 cm.The raft-soil stiffness ratios of the model rafts ranging from 0.39 to 10.56 cover flexible to very stiff rafts.The improvement in the ultimate bearing capacity is represented by the load improvement ratio,LIR,and the reductions in average settlement and differential settlement are represented by the settlement ratio,SR,and the differential settlement ratio,DSR,respectively.The effects of the number of settlement reducing piles,raft relative stiffness,and the slenderness ratio of piles on the load improvement ratio,settlement ratio and differential settlement ratio are presented and discussed.The results of the tests show the effectiveness of using piles as settlement reduction measure with the rafts.As the number of settlement reducing piles increases,the load improvement ratio increases and the differential settlement ratio decreases.

关键词： Raft Settlement reducing piles Piled raft Model tests Sand soil

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General exact solution of the fin problem with variable thermal conductivity

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Propulsion and Power Research 2016年第1期5卷 63-69页

作者： Abass H.abdel Kader mohamed S.abdel Latif hamed M.Nour Engineering Mathematics and Physics Department Faculty of EngineeringMansoura UniversityMansoura 35516Egypt

In this paper,Lie point symmetry method is used to obtain the general exact solution of the second order nonlinear ordinary differential equation which goveming heat transfer in rectangular fin with variable thermal conductivity.Some new forms of thermal conductivity are introduced and the associated exact solution is obtained in each case.The general relation among the fin efficiency,thermal conductivity and thermo-geometric parameter is obtained.

关键词： Exact solution Fin Thermal conductivity Heat transfer Lie point symmetry

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Evaluation of children and adults with post-COVID-19 persistent smell,taste and trigeminal chemosensory disorders:A hospital based study

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World Journal of Clinical Pediatrics 2023年第3期12卷 133-150页

作者： Sherifa Ahmed hamed Eman Bahaa Kamal-Eldeen mohamed Azzam abdel-Razek Ahmed Department of Neurology and Psychiatry Assiut UniversityFaculty of MedicineAssiut 71516Egypt Department of Pediatrics Assiut UniversityFaculty of MedicineAssiut 71516Egypt Department of ENT Assiut UniversityFaculty of MedicineAssiut 71516Egypt

BACKGROUND Smell disorders are the most frequent persistent coronavirus disease 2019(COVID-19)complications.AIM To describe the patterns and characteristics of persistent smell and taste disorders in Egyptian patients.METHODS Assessment was done to 185 patients(adults=150,age:31.41±8.63 years;children=35;age:15.66±1.63 years).Otolaryngology and neuropsychiatric evaluations were done.Measurements included:A clinical questionnaire(for smell and taste);sniffin'odor,taste and flavor identification tests and the Questionnaire of Olfactory Disorders-Negative Statements(sQOD-NS).RESULTS Duration of disorders was 11.53±3.97 ms(6-24 ms).Parosmia(n=119;64.32%)was developed months after anosmia(3.05±1.87 ms).Objective testing showed anosmia in all,ageusia and flavor loss in 20%(n=37)and loss of nasal and oral trigeminal sensations in 18%(n=33)and 20%(n=37),respectively.Patients had low scoring of sQOD-NS(11.41±3.66).There were no specific differences in other demographics and clinical variables which could distinguish post-COVID-19 smell and taste disorders in children from adults.CONCLUSION The course of small and taste disorders are supportive of the nasal and oral neuronal compromises.Post-COVID-19 taste and trigeminal disorders were less frequent compared to smell disorders.Post-COVID-19 flavor disorders were solely dependent on taste and not smell disorders.There were no demographics,clinical variables at onset or specific profile of these disorders in children compared to adults.

关键词： Post-COVID-19 complications Anosmia Ageusia Trigeminal sensory loss Parosmia Quality of life

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Flavonoid chemical composition and antidiabetic potential of Brachychiton acerifolius leaves extract

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Asian Pacific Journal of Tropical Biomedicine 2017年第5期7卷 389-396页

作者： Aisha Hussein Abou Zeid mohamed Ali Farag Manal abdel Aziz hamed Zeinab abdel Aziz Kandil Radwa Hassan El-Akad Hanaa mohamed El-Rafie Pharmacognosy Department National Research Centre Pharmacognosy Department College of PharmacyCairo University Therapeutic Chemistry Department National Research Centre

Objective:To evaluate Brachychiton acerifolius leaf extracts as antidiabetic potential agent and to identify the main active constituents using bioactivity guided fractionation.Methods:In vitro antioxidant activity was evaluated for B.acerifolius different extracts using DPPH assay and vitamin C as control.Antidiabetic activity was then determined using STZ-induced rats treated daily with ethyl acetate and 70% ethanol leaf extracts for4 weeks at a dose of 200 g/kg body weight against gliclazide reference drug.Blood glucose,a-amylase,lipid profile,liver function enzymes and oxidative stress markers were assessed along with histopathological study for liver and pancreatic tissues.Isolation and structural elucidation of active compounds were made using Diaion and Sephadex followed by spectral analyses.Results:The results indicated that ethyl acetate and ethanol leaf extracts exhibited the strongest antioxidant activity compared to that of vitamin C(IC500.05,0.03 and 12 mg/m L,respectively).Both extracts showed potent anti-hyperglycemic activity evidenced by a significant decrease in serum glucose levels by 82.5% and 80.9% and a-amylase by45.2% and 53.6%,as compared with gliclazide 68% and 59.4%,respectively.Fractionation of ethanol extract resulted in the isolation of 9 flavonoids including apigenin-7-O-arhamnosyl(1/2)-b-D-glucuronide,apigenin-7-O-b-D-glucuronide,apigenin-7-O-b-Dglucoside and luteolin-7-O-b-D-glucuronide.Conclusions:This study highlights the potential use of B.acerifolius leaf extract enriched in flavones for the treatment of diabetes that would warrant further clinical trials investigation.

关键词： STZ-induced diabetes Diaion fractionation Flavonoid glucuronides Brachychiton acerifolius

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Novel non-invasive biological predictive index for liver fibrosis in hepatitis C virus genotype 4 patients

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World Journal of Hepatology 2016年第32期8卷 1392-1401页

作者： Mahmoud Khattab mohamed Amin Sakr mohamed abdel fattah Youssef Mousa Elwy Soliman Ashraf Breedy Mona Fathi Salwa Gaber Ahmed Altaweil Ashraf Osman Ahmed Hassouna Ibrahim Motawea Department of Internal Medicine Minia University Department of Tropical Medicine Ain Shams University Department of Clinical Pathology Ain Shams University Department of Pathology Minia University Department of Pathology Ain Shams University Department of Clinical Pathology Minia University Department of Cardiothoracic Surgery Ain Shams University

AIM To investigate the diagnostic ability of a non-invasive biological marker to predict liver fibrosis in hepatitis C genotype 4 patients with high accuracy.METHODS A cohort of 332 patients infected with hepatitis C genotype 4 was included in this cross-sectional study. Fasting plasma glucose, insulin, C-peptide, and angiotensinconverting enzyme serum levels were measured. Insulin resistance was mathematically calculated using the homeostasis model of insulin resistance(HOMA-IR).RESULTS Fibrosis stages were distributed based on Metavir score as follows: F0 = 43, F1 = 136, F2 = 64, F3 = 45 and F4 = 44. Statistical analysis relied upon reclassification of fibrosis stages into mild fibrosis(F0-F) = 179, moderate fibrosis(F2) = 64, and advanced fibrosis(F3-F4) = 89. Univariate analysis indicated that age, log aspartate amino transaminase, log HOMA-IR and log platelet count were independent predictors of liver fibrosis stage(P < 0.0001). A stepwise multivariate discriminant functional analysis was used to drive a discriminative model for liver fibrosis. Our index used cut-off values of ≥ 0.86 and ≤-0.31 to diagnose advanced and mild fibrosis, respectively, with receiving operating characteristics of 0.91 and 0.88, respectively. The sensitivity, specificity, positive predictive value, negative predictive value and positive likelihood ratio were: 73%, 91%, 75%, 90% and 8.0 respectively for advanced fibrosis, and 67%, 88%, 84%, 70% and 4.9, respectively, for mild fibrosis.CONCLUSION Our predictive model is easily available and reproducible, and predicted liver fibrosis with acceptable accuracy.

关键词：肝纤维变性胰岛素抵抗 Aspartate 氨基的 transaminase 血小板年龄

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Purang Ultramafic Complex and Their Geological Origin, Southwest Tibet

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Acta Geologica Sinica(English Edition) 2015年第A02期89卷 22-24页

作者： hamed Gamal El Dien mohamed Hamdy abdel Salam Abu EI-Ela Adel Hassan Youngwoo Kil Geology Department FaculW of Science Tanta University 31527 Tanta Egypt Department of earth sciences school of natural science kanazawa university Japan Department of Energy and Resources Engineering College of Engineering Chonnam National University Yongbong-roBuk-gu Gwangju Korea

Neoproterozoic ophiolitic Serpentinites are common in the Arabian-Nubian Shield （ANS） of the Eastern Desert （ED） of Egypt, which were formed in arc stage in different tectonic setting. Thus they might subject to exchange with the crustal material derived from recycling subducting oceanic lithosphere. This caused metasomatism enriching the rocks in incompatible elements and forming non- residual minerals. Herein,

关键词： OPHIOLITES RESEARCH SERPENTINITE METASOMATISM (Mineralogy) RARE earths EARTH'S mantle

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Behavior of raft on settlement reducing piles:Experimental model study

Behavior of raft on settlement reducing piles:Experimental m...

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第13届全国岩石动力学学术会议

作者： Basuony El-Garhy Ahmed abdel Galil abdel-fattah Youssef mohamed Abo Raia Civil Engineering Department Faculty of EngineeringMinufiya UniversityShebin El-KomEgypt

An experimental program is conducted on model piled rafts in sand soil.The experimental program is aimed to investigate the behavior of raft on settlement reducing piles.The testing program includes tests on models of single pile,unpiled rafts and rafts on 1,4,9,or 16 piles.The model piles beneath the rafts are closed ended displacement piles installed by driving.Three lengths of piles are used in the experiments to represent slenderness ratio,L/D,of 20,30 and 50,respectively.The dimensions of the model rafts are 30 cm x 30cm with different thickness of 0.5 cm,1.0 cm or 1.5 cm.The raft-soil stiffness ratios of the model rafts ranging from 0.39 to 10.56 cover flexible to very stiff rafts.The improvement in the ultimate bearing capacity is represented by the load improvement ratio,LIR,and the reductions in average settlement and differential settlement are represented by the settlement ratio,SR,and the differential settlement ratio,DSR,respectively.The effects of the number of settlement reducing piles,raft relative stiffness,and the slenderness ratio of piles on the load improvement ratio,settlement ratio and differential settlement ratio are presented and discussed.The results of the tests show the effectiveness of using piles as settlement reduction measure with the rafts.As the number of settlement reducing piles increases,the load improvement ratio increases and the differential settlement ratio decreases.

关键词： Raft Settlement reducing piles Piled raft Model tests Sand soil

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Machine Transliteration

Machine Transliteration

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第20届亚太地区语言、信息和计算国际会议

作者： mohamed abdel fattah Shingo Kuroiwa Faculty of Engineering University of Tokushima 2-1 Minantijosanjima Tokushima Japan 770-8506

In the present study, we present different approaches for transliteration proper noun pair’s extraction from parallel corpora based on different similarity measures between the English and Romanize

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Annexin A2 as a biomarker for hepatocellular carcinoma in Egyptian patients

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World Journal of Hepatology 2017年第9期9卷 469-476页

作者： mohamed K Shaker Hanzada I abdel fattah Ghada S Sabbour Iman F Montasser Sara M abdelhakam Eman El Hadidy Rehab Yousry Ahmed K El Dorry Department of Tropical Medicine Faculty of MedicineAin Shams University Department of Clinical Pathology Faculty of MedicineAin Shams University Department of Radiodiagnosis and Inter-ventional Radiology Faculty of MedicineAin Shams University

AIM To investigate the clinical utility of serum annexin A2(ANXA2) as a diagnostic marker for early hepatocellular carcinoma(HCC).METHODS This study was performed in HCC Clinic of Ain Shams University Hospitals, Cairo, Egypt and included: Group 1: Fifty patients with early stage HCC(Barcelona Clinic Liver Cancer stage A); Group 2: Twenty five patients with chronic liver disease; and Control Group: Fifteen healthy, age-and sex-matched subjects who were seronegative for viral hepatitis markers. The followinglaboratory investigations were done: Viral hepatitis markers [hepatitis B surface antigen and hepatitis C virus(HCV) antibodies], HCV RNA in HCV antibody-positive patients, serum alpha fetoprotein(AFP), and serum ANXA2 levels.RESULTS In this study, 88% of HCC patients(n = 44) were HCVpositive, while HBV infection represented only 8% of all HCC patients(n = 4); and two patients were negative for both viral markers. A highly significant difference was found between patients with HCC and chronic liver disease as well as controls with regard to serum ANXA2 levels(130, IQR 15-240; 15, IQR 15-17; and 17, IQR 15-30 ng/m L, respectively). The area under the curve of ANXA2 was 0.865; the cut-off value was established to be 18 ng/mL with a diagnostic sensitivity of 74% and a specificity of 88%, while the sensitivity and specificity of AFP at the cut-off value of 200 ng/dL were 20% and 100%, respectively.CONCLUSION Serum ANXA2 may serve as a biomarker for the early detection of HCC.

关键词： Hepatocellular carcinoma Hepatitis C virus Annexin A2 Alpha-fetoprotein Tumor markers

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