检索结果-南通市图书馆

World Journal of Cardiovascular Diseases 2019年第11期9卷 781-795页

作者： Wassam Eldin Elshafey Walaa Farid Abdel Aziz Ahmed Magdy Kamal Eldin mohamed mahmoud khattab Menoufia University Shibin El Kom Al Minufya Egypt

Background: Chronic kidney disease patients are at a greater risk for nephropathy requiring dialysis after percutaneous coronary intervention. Such patients are usually deferred due to fear of “Renalism”.?Objectives This study assesses the outcome of Low dose contrast protocol during PCI in CKD patients whose e-GFR 60 ml/min/1.72 m and investigates a safety margin for contrast use in these high-risk categories.?Methods: Patients were into three groups according to CV/e-GFR ratio: Group (A) low-dose: CV/e-GFR ratio 2.0 Group (B) medium-dose: CV/e-GFR ratio > 2.0 and × bodyweight\***). Group (C) high-dose: CV/e-GFR ratio > MACD. Results: A total of 73 patients were enrolled. Average age was 54 ± 8 years,81.4% were male and 18.6% were females and 52% were diabetic. Mean baseline e-GFR was 40 ± 8.0 ml/min/1.73m2. Contrast Volume used in group A was (58.26 ± 15.05) (n = 24), in group B (109.42 ± 17.11) (n = 26) and in group C (304.5 ± 60.30) (n = 23), respectively. The incidences of CI-AKI in the 3 groups were 0%, 11.5% and 35%, respectively (p = 0.02). All-cause death 0%, 17% and introduction of maintenance hemo dialysis was 0%, 11.5% and 26%, respectively (p Conclusion: Low dose contrast protocol is safe, effective and easily applicable technique without CI-AKI or death.

关键词： Chronic Kidney Disease (CKD) Maximum Allowed Contrast Dose (MACD) Contrast Induced Acute Kidney Injury (CI-AKI) Low Dose Protocol Contrast Volume to e-GFR Ratio

Targeting host factors:A novel rationale for the management of hepatitis C virus

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2009年第28期15卷 3472-3479页

作者： mahmoud Aboelneen khattab Department of Internal Medicine El-Minia University

Hepatitis C is recognized as a major threat to global public health. The current treatment of patients with chronic hepatitis C is the addition of ribavirin to interferon-based therapy which has limited efficacy, poor tolerability, and significant expense. New treatment options that are more potent and less toxic are much needed. Moreover, more effective treatment is an urgent priority for those who relapse or do not respond to current regimens. A major obstacle in combating hepatitis C virus （HCV） infection is that the fidelity of the viral replication machinery is notoriously low, thus enabling the virus to quickly develop mutations that resist compounds targeting viral enzymes. Therefore, an approach targeting the host cofactors, which are indispensable for the propagation of viruses, may be an ideal target for the development of antiviral agents because they have a lower rate of mutation than that of the viral genome, as long as they have no side effects to patients. Drugs targeting, for example, receptors of viral entry, host metabolism or nuclear receptors, which are factors required to complete the HCV life cycle, may be more effective in combating the viral infection. Targeting host cofactors of the HCV life cycle is an attractive concept because it imposes a higher genetic barrier for resistance than direct antiviral compounds. However the principle drawback of this strategy is the greater potential for cellular toxicity.

关键词： Host factors Hepatitis C virus Noveltreatment Cell entry Host metabolism Nuclearreceptors Insulin resistance

Resistance to acid degradation,sorptivity,and setting time of geopolymer mortars

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Structural and Civil Engineering 2022年第6期16卷 781-791页

作者： Osama A mohamed Rania AL-khattab Waddah AL-HAWAT College of Engineering Abu Dhabi UniversityAbu DhabiUnited Arab Emirates

Experimental evaluations were conducted to determine the water sorptivity,setting time,and resistance to a highly acidic environment,of mortar with alkali-activated ground granulated blast furnace slag(GBS)binder and also of combinations of fly ash and GBS *** were activated using mixtures of NaOH and Na_(2)SiO_(3)*** molarity of NaOH in the mixtures ranged from 10 mol·L^(−1)to 16 mol·L^(−1),and the Na_(2)SiO_(3)/NaOH ratio was varied from 1.5 to *** samples were produced using three binder combinations:1)GBS as the only binder;2)blended binder with a slag-to-fly ash ratio of 3:1;and 3)mixed binder with 1:1 ratio of slag to fly *** samples were mixed and cured at(22±2)°C till the day of the *** impact of activator solution alkalinity,activator ratio Na_(2)SiO_(3)/NaOH,GBS content on the rate of water absorption were *** 7,28,and 90 d of immersion in a 10%sulfuric acid solution,the resistance of a geopolymer matrix to degradation was assessed by measuring the change in sample *** influence of solution alkalinity and relative fly ash content on setting times was ***-activated mortar with a slag-to-fly ash ratio of 3:1 had the least sorptivity compared to the two other binder combinations,at each curing age,and for mortars made with each of the NaOH alkaline activator *** sorptivity decreased with age and sodium hydroxide concentrations,suggesting the production of geopolymerization *** reduction in weight of sample occurred after immersion in the strong acid H_(2)SO_(4)solution for three months,regardless of binder *** was due to the synthesis of hydration and geopolymerization products in the presence of curing water,which outweighed the degradation of the geopolymer matrix caused by sulfuric acid.

关键词： alkali-activated materials fly ash sorptivity durability of concrete sodium hydroxide sodium silicates reduction in CO_(2)emissions sulfuric acid

Analysing user daylight preferences in heritage buildings using virtual reality

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Building Simulation 2022年第9期15卷 1561-1576页

作者： mohamed Marzouk Maryam ElSharkawy Ayman mahmoud Department of Structural Engineering Faculty of EngineeringCairo University12613GizaEgypt Department of Architecture Engineering Faculty of EngineeringCairo University12613GizaEgypt

Technology has always been creating effective ways to support human *** virtual reality(IVR)has emerged to engage users in a simulated world,and this has gained the interest of a wide variety of users in the heritage industry.A historical case study built in the early 19th century is considered for an adaptive reuse *** palace is located in Cairo,Egypt,and named after Prince Omar *** current palace state incorporates a smashed top-lit zone,which is being studied and analyzed for daylighting *** simulated distinct optimum skylight configurations are suggested for the redesign where the selection should not be based solely on simulation data,but should consider real-user *** daylight design criteria are previously based on simulation data that do not necessarily indicate the users'*** utilizing user interactive tools such as IVR to test daylight redesign options,a whole new dimension is *** this study,the VR users’survey data is statistically analyzed using Statistical Package for Social Sciences(SPSS),where results revealed that the assessment attributes succeeded in reflecting the users'preferences;which,motivated designers to consider potential users’daylight preferences in reused *** paper highlights the most significant emotional attributes that provide cost-effective and reliable information concerned with the performance of daylight in IVR before design *** study compares and analyzes the effect of three skylight designs(Cases A,B&C)on the users'perception before design implementation using(IVR)***-eight participants have contributed to the study,providing their feedback on six attributes namely:Pleasant,Contrasting,Brightness,Uniform Distribution,Visual Comfort,and *** attributes are evaluated for the three cases in space using five scale rating values to reveal that the"Pleasant"attribute is most reliable in the study to reflect th

关键词： daylight preferences heritage buildings rehabilitation immersive virtual reality statistical analysis

Seismic performance of high-rise buildings in selected regions in Saudi Arabia according to different seismic codes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Earthquake Engineering and Engineering Vibration 2021年第1期20卷 179-191页

作者： Sayed mahmoud mohamed Alsearheed Waleed Abdallah Department of Civil and Construction Engineering College of EngineeringImam Abdulrahman Bin Faisal UniversitySaudi Arabia Department of Building Engineering College of ArchitectureImam Abdulrahman Bin Faisal UniversitySaudi Arabia Department of Civil Engineering College of Engineering at MatariaHelwan UniversityCairoEgypt

The design code for each country is revised and updated based on an expected zone’s seismic intensities,geotechnical site classifications,structural systems,construction materials and methods of construction in order to provide more realistic considerations of seismic demand,seismic response,and seismic *** on the aforementioned provisions,structures designed according to different seismic codes may yield different performances for the same level of *** study aims to investigate and compare the induced responses related to the earthquake-resistant design of reinforced concrete(RC)buildings according to the Saudi building code(SBC-301),American code(ASCE-7),uniform building code(UBC-97),and European code(EC-8).In order to account for the provision regarding the hazard specification and its effect on the induced seismic responses,four regions in the Kingdom of Saudi Arabia with different seismic levels are *** code provisions related to the specification of site classification and its effect on the induced design base shear are investigated as *** differences are observed in the induced responses with the variation in seismic design codes for the considered seismic hazards and site classifications.

关键词： high-rise building SBC-301 international seismic codes seismic zones site classifications

The Rank of the 2-Class Group of Some Fields with LargeDegree

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Algebra Colloquium 2022年第2期29卷 181-188页

作者： mohamed mahmoud Chems-Eddin Department of Mathematics Faculty of Sciences Dhar El Mahraz Sidi Mohamed Ben Abdellah UniversityFezMorocco

Let n≥3 be an integer and d an odd square-free *** compute the rank of the 2-class group of some fields of the form L_(n,d)=Q(ζ_(2^(n)),√d)when all the prime divisors of d are congruent to±3(mod 8)or 9(mod 16).

关键词： cyclotomic Z_(2)-extension 2-rank 2-class group

Unveiling the complexities of microbiologically induced corrosion:mechanisms,detection techniques,and mitigation strategies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2024年第10期18卷 15-48页

作者： mahmoud A.Ahmed Safwat A.mahmoud Ashraf A.mohamed Veolia Water Technologies Cairo 11835Egypt Chemistry department Faculty of ScienceAin Shams UniversityCairo 11566Egypt Physics Department Faculty of ScienceNorthern Border UniversityArar 13211Saudi Arabia

Microbiologically induced corrosion(MIC)is a complex and destructive phenomenon that occurs in various sectors,involving the interaction between microorganisms and metal surfaces,resulting in accelerated corrosion *** review article provides a comprehensive analysis of MIC,encompassing microbial species involved,their metabolic activities,and influential environmental factors driving the corrosion *** mechanisms of MIC,both in the presence and absence of oxygen,are explored,along with the diverse effects of microbes on different types of corrosion and their economic *** and monitoring techniques,including traditional and advanced methods such as microbiological and electrochemical methods,are ***,it examines preventive and control measures,such as the use of biocides and their mechanisms of *** to enhance the performance of these control measures and the effectiveness of antimicrobial agents during disinfection processes,including surfactants and chelators,are ***,the review highlights enzymatic remediation as a sustainable alternative approach,providing detailed *** challenges in mitigating MIC and potential future developments and collaborative opportunities are also *** systematic review is a valuable resource for researchers,industry professionals,and policymakers seeking a comprehensive understanding of the complex phenomenon of MIC and effective strategies for its management.

关键词： Metal failure Biofilm formation Enzymatic remediation Antimicrobial agents Bio-corrosion mechanisms

Role of biomarkers in the prediction and diagnosis of hepatocellular carcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2015年第23期7卷 2474-2481页

作者： mahmoud khattab Magdy Fouad Elham Ahmed Internal Medicine Depart-ment Minia University Tropical Medicine Department Minia University

The prevalence of hepatocellular carcinoma(HCC)has progressively increased in recent years and is now thefifth and the second most common cancer in the World and in Egypt,*** work has focused in the development of assays for detecting hepatic carcinogensis before the observance of hepatic focal *** attention has been directed towards HCC-specific biomarkers for use in the early diagnosis of HCC and in the confirmation of radiological *** a number of biomarkers have been identified,none have been considered reliable indicators of early HCC *** review presents a few of the most relevant HCC biomarkers and suggests improvements to the accuracy of diagnostic assays through their combined ***,we present an algorithm for the biomarker-based diagnosis of HCC and highlight its important role in the early prediction of HCC.

关键词： Hepatocellular carcinoma Epidemiology Pathogenesis

ON SINGULAR EQUATIONS INVOLVING FRACTIONAL LAPLACIAN

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta Mathematica Scientia 2020年第5期40卷 1289-1315页

作者： Ahmed YOUSSFI Ghoulam OULD mohamed mahmoud National School of Applied Sciences Sidi mohamed Ben Abdellah University-Fez Laboratory of Mathematical Analysis and Applications My Abdellah Avenue Road ImouzerP.O.Box 72 Fes-Principale30000FezMorocco National School of Applied Sciences Sidi mohamed Ben Abdellah University-Fez My Abdellah Avenue Road ImouzerP.0.Box 72 Fes-Principale30000FezMorocco

We study the existence and the regularity of solutions for a class of nonlocal equations involving the fractional Laplacian operator with singular nonlinearity and Radon measure data.

关键词： fractional Laplacian singular elliptic equations measure data

Price Prediction of Seasonal Items Using Machine Learning and Statistical Methods

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2022年第2期70卷 3473-3489页

作者： mohamed Ali mohamed Ibrahim mahmoud El-Henawy Ahmad Salah Faculty of Computers and Informatics Zagazig UniversityZagazigEgypt

Price prediction of goods is a vital point of research due to how common e-commerce platforms *** are several efforts conducted to forecast the price of items using classicmachine learning algorithms and *** models can predict prices of various financial instruments,e.g.,gold,oil,cryptocurrencies,stocks,and second-hand *** these efforts,the literature has no model for predicting the prices of seasonal goods(e.g.,Christmas gifts).In this context,we framed the task of seasonal goods price prediction as a regression ***,we utilized a real online trailer dataset of Christmas gifts and then we proposed several machine learningbased models and one statistical-based model to predict the prices of these seasonal ***,we utilized a real-life dataset of Christmas gifts for the prediction ***,we proposed support vector regressor(SVR),linear regression,random forest,and ridgemodels as machine learningmodels for price ***,we proposed an autoregressive-integrated-movingaverage(ARIMA)model for the same purpose as a statistical-based ***,we evaluated the performance of the proposed models;the comparison shows that the best performing model was the random forest model,followed by the ARIMA model.

关键词： ARIMA machine learning price prediction random forest ridge support vector regressor