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High fat diet dysregulates m.c.o.NA-17-5p and triggers retinal inflam.atio.:Ro.e o. endo.lasm.c.retic.lum.stress

Wo.ld Jo.rnal o. Diab.tes 2017年第2期8卷 56-65页

作者： m.ha c.uc.a Islam.N mohamed Sally L Elshaer o.inakac.uk m.ata m.gan L b.rtasis Azza b.El-Rem.ssy c.inic.l and Experim.ntal Therapeutic. College of PharmacyUniversity of GeorgiaAugustaGA 30912United States

AIm.To.eluc.date ho. high diet-induc.d endo.lasm.c.retic.lum.stress upregulates thio.edo.in interac.ing pro.ein expressio. in m.ller c.lls leading to.retinal inflam.atio.. m.THo.S m.le c.7b./J m.c. were fed either no.m.l diet o. 60% high fat diet fo. 4-8 wk. During the 4 wk study, m.c. rec.ived phenyl-b.tyric.ac.d(Pb.); endo.lasm.c.retic.lum.stress inhib.to.; fo. 2 wk. Insulin resistanc. was assessed b. o.al gluc.se to.eranc.. Effec.s o. palm.tate-b.vine serum.alb.m.n(b.A)(400 μm.l/L) were exam.ned in retinal m.ller glial c.ll line and prim.ry m.ller c.lls iso.ated fro.0}wild type and thio.edo.in interac.ing pro.ein kno.1}-o.t m.c.. Expressio. o. thio.edo.in interac.ing pro.ein, endo.lasm.c.retic.lum.stress m.rkers, m. R-17-5p m.RNA, as well as nuc.eo.ide-b.nding o.igo.0}rizatio. do.0}in-like rec.pto. pro.ein(NLRP3) and IL1β pro.ein was *** High fat diet fo. 8 wk induc.d o.14}sity and insulin resistanc. evident b. inc.eases in b.dy weight and im.aired gluc.se to.eranc.. b. perfo.m.ng quantitative real-tim. po.ym.rase c.ain reac.io., we fo.nd that high fat diet triggered the expressio. o. retinal endo.lasm.c.retic.lum.stress m.rkers(P c.s were asso.1}ated with inc.eased thio.edo.in interac.ing pro.ein and dec.eased m. R-17-5p expressio., whic.were resto.ed b. inhib.ting endo.lasm.c.retic.lum.tress with Pb.(P o. palm.tate-b.A triggered endo.lasm.c.retic.lum.stress m.rkers, whic. was ac.o.0}anied with reduc.d m. R-17-5p and induc.d thio.edo.in interac.ing pro.ein m.RNA in retinal m.ller glial c.ll line(P m.tate upregulated NLRP3 and IL1β expressio. in prim.ry m.ller c.lls iso.ated fro.0}wild type. Ho.ever, using prim.ry m.ller c.lls iso.ated fro.0}thio.edo.in interac.ing pro.ein kno.1}-o.t m.c. ab.lished palm.tate-m.diated inc.ease in NLRP3 and IL1β.c.Nc.USIo. o.r wo.k suggests that targeting endo.lasm.c.retic.lum.tress o. thio.edo.in interac.ing pro.ein are po.ential therapeutic.strategies fo. early interventio. o. o.

关键词： High fat diet Palm.tate Endo.lasm.c.retic.lum.stress Inflam.atio. Thio.edo.in-interac.ing pro.ein m.c.o.RNA 17-5p

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o.tim.m.Tim.ng and c.m.lic.tio. o. c.m.letio. Thyro.dec.o.0} fo. Differentiated Thyro.d c.nc.r

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Jo.rnal o. c.nc.r Therapy 2017年第5期8卷 518-526页

作者： mohamed Ab.uelm.gd Salem.b.dawy m. Ahm.d m.hm.ud H. Elsho.eb. Surgic.l o.c.lo.y Departm.nt SECI Assiut University Assiut Egypt

b.c.gro.nd: Despite im.ro.ed preo.erative diagno.tic., inc.dental po.to.erative detec.io. o. differentiated thyro.d c.nc.r in the final histo.o.y is still c.m.o.. In m.st o. these c.ses, c.m.letio. thyro.dec.o.2} is rec.m.ended b. natio.al and internatio.al guidelines, altho.gh sec.ndary surgery is asso.1}ated with an inc.eased o.erative risk. The o.tim.l tim.ng o. c.m.letio. thyro.dec.o.2} is still c.ntro.ersial. Patients and m.tho.s: The patients adm.tted to.surgic.l o.c.lo.y departm.nt, SEc., with diagno.is o. differentiated thyro.d c.nc.r;during the perio. fro.2}January 2008 to.Dec.m.er 2015;were rewired fo. age, sex, type o. 1st o.eratio., histo.atho.o.ic.l result, type o. 2nd o.eratio. and tim. interval b.tween the 2 o.eratio., c.m.lic.tio. o. 2nd o.eratio. and m.rb.dity. 118 patients underwent c.m.letio. thyro.dec.o.2};tho.e patients were divided ac.o.ding to.tim.ng o. c.m.letio. o.eratio. into.3 gro.ps: Gro.p A is fro.2}o.e week to.3 m.nths and inc.ude 64 patients;Gro.p b.is fro.2}3 - 6 m.nths and inc.ude 30 patients;Gro.p c.is m.re than 6 m.nths and inc.ude 24 patients. c.inic.l c.m.lic.tio.s and o.c.lo.ic.o.tc.m.s were analyzed. The m.an fo.lo.-up was 80 ± 10 m.nths. Result: we rec.rd 118 patients under c.m.letio. thyro.dec.o.2}. Ages range fro.2}79 to.13 years. Papillary thyro.d c.nc.r were 96 and fo.lic.lar thyro.d c.nc.r were 22. The o.erall rates o. transient and persistent po.to.erative hypo.1}lc.m.a were 19.5% and 4.2%, respec.ively. The rates o. persistent hypo.1}lc.m.a were fo.nd in gro.p A and b.b.t no. in gro.p c. Transient o. persistent vo.1}l c.rd paresis was o.0}erved in 9 (7.6%) and 3 patients (2.5%). The inc.denc. o. persistent vo.1}l c.rd paresis (Vc.) was signific.ntly higher in gro.ps A and b.than in gro.p c. There was no.signific.nt differenc. regarding survival am.ng the 3 gro.ps;ho.ever rec.rrenc. is higher in gro.p A. c.nc.usio.: c.nsidering perio.erative m.rb.dity and o.c.lo.ic.o.tc.m.s, c.m.letio. thyro.dec.o.2} sho.ld b. perfo.m.d at least 3 to.6

关键词： o.tim.m Tim.ng c.m.letio. Thyro.dec.o.1}

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Evaluatio. o. Veno.s Am.o.ia Level, Splenic.Lo.gitudinal Diam.ter, Po.tal Vein and Splenic.Vein Diam.ters as No.-Invasive Indic.to.s fo. the Presenc. o. Po.to.ystem.c.c.llaterals in Egyptian c.rrho.ic.Patients

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o.en Jo.rnal o. Gastro.ntero.o.y 2014年第6期4卷 265-274页

作者： mohamed F. m.ntasser Heb. m. Ab.ella Am.r Helm. Sam. Internal m.dic.ne Faculty of Medicine Ain Shams University Cairo Egypt Tro.ic.l m.dic.ne Faculty of Medicine Ain Shams University Cairo Egypt

Intro.uc.io. and Aim.o. the Wo.k: The identific.tio. o. c.rrho.ic.patients with eso.hageal varic.s o. o.her po.to.ystem.c.c.llateral b. no.-invasive m.ans is appealing in that it c.uld dec.ease the nec.ssity o. endo.c.pic.sc.eening. This study was to.evaluate the diagno.tic.utility o. veno.s am.o.ia level with o.her ultraso.o.raphic.param.ters as no.-invasive m.rkers fo. the presenc. o. po.to.ystem.c.shunts. Patients and m.tho.s: The study inc.uded 3 gro.ps o. c.ild Pugh c.ass A and early b.patients. Gro.p (A): 25 patients with evidenc. o. b.th eso.hageal varic.s and po.to.ystem.c.c.llaterals;gro.p (b. 25 patients with neither evidenc. o. varic.s no. po.to.ystem.c.c.llaterals and gro.p (c.: 25 patients with evidenc. o. varic.s b.t no.c.llaterals. m.asurem.nt o. veno.s am.o.ia level was do.e fo. all patients. Results: serum.am.o.ia level was signific.ntly higher in gro.p A (222.8 ± 54 μg/dL) than that in gro.p b.(85 ± 21.1 μg/dL) and gro.p c.(148.2 ± 19.6 μg/dL). The c.t-o.f value o. serum.am.o.ia level 113 μg/dL was a go.d predic.o. fo. the presenc. o. eso.hageal varic.s, while the c.t-o.f value o. serum.am.o.ia level at 133 μg/dL was a go.d predic.o. fo. the presenc. o. b.th eso.hageal varic.s and ab.o.1}nal c.llaterals. c.m.inatio. o. po.tal vein diam.ter > 13m. + splenic.vein diam.ter > 8.9m. + am.o.ia level > 133 μg/dL gives 100% o. sensitivity and 96% o. spec.fic.ty fo. the predic.io. o. the presenc. o. po.to.ystem.c.shunts. c.nc.usio.: Determ.natio. o. serum.am.o.ia level, splenic. po.tal vein and splenic.vein diam.ters are c.nsidered as go.d predic.o.s fo. the presenc. o. po.to.ystem.c.shunts in patients with liver c.rrho.is.

关键词： Serum Am.o.ia Po.o.ystem.c c.llaterals Po.tal Hypertensio. Eso.hageal Varic.s Splenic Vein Diam.ter Po.tal Vein Diam.ter Splenic Lo.gitudinal Diam.ter

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The Effec. o. o.al Nifedipine versus Parenteral m.gnesium.Sulfate and Rito.rine fo. To.0}lysis in Patients with Threatened Preterm.Lab.r: A Rando.1}zed c.ntro.led Trial

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o.en Jo.rnal o. o.0}tetric. and Gynec.lo.y 2019年第8期9卷 1142-1150页

作者： Safwat A. Salm.n Dina Hab.b.mohamed Atef Ahm.d m. Ab.as Departm.nt o. o.1}tetric. & Gynec.lo.y Faculty of Medicine Assiut University Assiut Egypt Departm.nt o. o.1}tetric. & Gynec.lo.y Sohag Teaching Hospital Sohag Egypt

b.c.gro.nd: Preterm.lab.r is a serio.s c.use o. neo.atal m.rb.dity and m.rtality. This study aim. to.c.m.are the effec.s o. nifedipine, m.gnesium.sulfate and rito.rine as to.1}lytic.drugs in patients presented with threatened preterm.lab.r. Patients and m.tho.s: The c.rrent study was rando.2}zed c.ntro.led trial c.nduc.ed in So.ag Teac.ing Ho.pital b.tween No.em.er 2015 and Septem.er 2016. Patients were divided into. Gro.p A: 101 patients rec.ived intraveno.s rito.rine infusio.;Gro.p b. 101 patients rec.ived intraveno.s m.gnesium.sulfate;Gro.p c. 101 patients rec.ived o.al nifedipine. Different m.ternal and neo.atal o.tc.m.s were assessed. Results: The b.seline c.iteria were ho.2}geno.s am.ng the study gro.ps with no.statistic.lly signific.nt differenc.s. There is no.differenc. b.tween eac. o.her gro.p regarding the need fo. additio.al to.1}lysis o. the rate o. rec.rrenc. o. lab.ur pains. Nifedipine was asso.1}ated with the least length o. ho.pital stay. There is no.differenc. b.tween all gro.ps regarding the rate o. preterm.delivery b.fo.e full stero.d do.e (p > 0.05). Ho.ever, nifedipine gro.p was the least o.e in the rate o. o.1}urrenc. o. preterm.delivery within 7 days fro.2}initiatio. o. to.1}lytic.therapy. Sim.larly, nifedipine gro.p was asso.1}ated with higher gestatio.al age at delivery and signific.nt pro.o.gatio. o. pregnanc. than the o.her gro.ps. c.nc.usio.: o.al nifedipine use was asso.1}ated with less rec.rrenc. o. lab.r pains, less need fo. additio.al to.1}lysis, less duratio. o. ho.pital stay, and m.re patient satisfac.io. in patients with threatened preterm.lab.ur.

关键词： To.0}lysis Preterm Lab.ur Nifedipine Rito.rine

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Therapeutic.m.m.o.lasty in m.nagem.nt o. b.east c.nc.r: A Pro.pec.ive c.inic.l Study

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Advanc.s in b.east c.nc.r Researc. 2017年第4期6卷 107-116页

作者： Ahm.d mohamed Farahat Am. Ab.el m.guid Attia mohamed Aly m. El Shafei El Zawahry mohamed H. Zedan Hussein o.am. So.im.n Natio.al c.nc.r Institute Cairo University Giza Egypt

b.c.gro.nd: The intro.uc.io. o. o.c.plastic.reast surgery, with a c.nc.m.tant c.ntralateral sym.etrizatio. pro.1}dure, allo.s the surgic.l o.c.lo.ist the freedo.7}to.perfo.m.wider exc.sio.s, with m.re favo.ab.e c.sm.tic.o.tc.m.s. o.0}ec.ive: To.assess the feasib.lity o. b.lateral b.east reduc.io. fo. the m.nagem.nt o. b.east c.nc.r, and to.determ.ne the m.st suitab.e surgic.l tec.nique o. therapeutic.m.m.o.lasty fo. eac. patient. And to.evaluate the c.sm.tic.o.tc.m. during the po.to.erative perio.. m.tho.s: This study was fro.7}June 2014 until June 2016, and inc.uded 86 fem.le patients with b.east c.nc.r;divided in 3 gro.ps;gro.p A;had b.lateral superio. pedic.e reduc.io. m.m.o.lasty, gro.p b.had b.lateral inferio. pedic.e reduc.io. m.m.o.lasty, gro.p c.had b.lateral b.twing m.sto.exy. 1 m.nth po.to.erative, patients were asked to.answer a 5-sc.le questio.naire evaluating their o.n c.sm.tic.o.tc.m.. c.iteria they were asked to.evaluate were: sym.etry, shape and vo.um., pro.ec.io., c.rrec.io. o. pto.is, visib.lity o. the sc.rs and o.erall satisfac.io.. A sim.lar questio.naire was answered b. a panel m.de up o. a surgeo. and b.east-c.re nurse after seeing the pre- and po.t-o.erative pho.o. o. the patients in questio.. Results: Gro.p A had a m.an tum.r size o. 2.7 ± 0.69 c.0} least resec.ed m.rgins 1.2 - 4.3 c.0} Gro.p b.had a m.an tum.r size o. 3.2 ± 1.19 c.0} least resec.ed m.rgins 0.7 - 3.8 c.0} Gro.p c.had a m.an tum.r size o. 3.4 ± 1.12 c.0} least resec.ed m.rgins 1.7 - 5.2 c.0} c.sm.tic.results fared high ab.ve average. Gro.p c.fared b.tter in o.erall satisfac.io. b.t Gro.p b.fared b.tter in pto.is c.rrec.io., pro.ec.io. and sym.etry. The panel answers sho.ed differenc. regarding shape and vo.um.;the o.ly two.c.iteria to.b. alm.st o. the sam. result am.ng the three gro.ps. c.nc.usio.: b.lateral Tm.has so.7} advantages when c.m.ared to.standard c.nventio.al b.0} tec.niques witho.t having any unfavo.ab.e effec.s o. surgic.l m.rgin c.nfidenc., lo.1}l rec.rrenc., and survival rat

关键词： b.east o.c.plasty Therapeutic m.m.o.lasty Surgery o.c.lo.y Plastic Sym.etry

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Hydro.0}tallurgy two.stage pro.1}ss fo. preparatio. o. (Nd,La,c.)_(2)o.(3) fro.0}end-o.-life Nim. b.tteries

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Jo.rnal o. Rare Earths 2024年第2期42卷 415-423,I0007页

作者： Karim.Tanji Khalid o.zao.it mohamed b.lghiti Isam.Lam.ayety Hakim.Faqir Intissar b.nzako.r c.ntre de rec.erc.e REm.NEX-Gro.pe m.NAGEm MarrakechMorocco

The present wo.k aim. to.investigate the rec.very o. light rare earth elem.nts(LREEs) o.ides fro.0}end-o.life Nim. b.tteries using a hydro.m.tallurgic.l pro.1}ss fo.lo.ed b. effec.ive *** o.eratio.al leac.ing param.ters suc. as pho.pho.ic.ac.d c.nc.ntratio.,tem.erature,and the so.id-liquid ratio.were first o.tim.zed b. b.x-b.hnken *** results reveal that under o.tim.m.c.nditio.s([H_(3)Po.(4)]=2 m.l/L,T=80℃,and S/L=1:10 g/m.) the leac.ing effic.enc.es o. Ni,c. reac. 98.1% and99.3%.While La,c.,and Nd elem.nts rem.in in the leac.ing residue as(La,c.,Nd)Po.(4) with yields o. 98.2%,98.6%,and 99.6% fo. La,c.,and Nd,***,the(La,c.,Nd)Po.(4) is leac.ed with Hc. ac.d,then the rare earth o.alate was prec.pitated using o.alic.ac.d at a pH o. 1.8 and then the pro.uc. was c.lc.ned at 800℃ fo. 2 h in o.der to.synthesize the(Nd,La,c.)_(2)o.(3).The analysis using sc.nning elec.ro. m.c.o.c.py(SEm. c.upled with energy dispersive X-ray spec.ro.c.py(EDX) c.nfirm. the ho.0}geneity o.(Nd,La,c.)_(2)o.(3) partic.es that have two.m.rpho.o.ies,i.e.,flo.er and stic.s with a partic.e size b.tween 3and 6 μ*** unit c.ll param.ters o.(Nd,La,c.)_(2)o.(3) were c.lc.lated after Rietveld refinem.nt o. the XRD patterns,in the spac. gro.p o. Fm.3m.are a=b.c.0.57921 nm.and the vo.um. equal to.0.194322 nm.(3).

关键词： Nim. b.tteries Hydro.0}tallurgic.l pro.1}ss Leac.ing Pho.pho.ic.ac.d b.x-b.hnken Light rare earth o.ides

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Interm.ttent fasting and the liver: Fo.1}s o. the Ram.dan m.del

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Wo.ld Jo.rnal o. Hepato.o.y 2024年第8期16卷 1070-1083页

作者： mohamed H Em.ra Hanan So.im.n Eb.da m.Said Hassan Elb.tae m.stafa Elazab.Shady Elhefnawy Tarik I Zaher Ahm.d Ab.el-Razik mohamed Elnadry Departm.nt o. Hepato.o.y Gastroenterology and Infectious DiseasesKafrelsheikh UniversityKafr-Elshikh 33516Egypt Departm.nt o. m.dic.ne Alyousif HospitalAlkhobar 34622Saudi Arabia Departm.nt o. Tro.ic.l m.dic.ne and Infec.io.s Diseases Tanta UniversityTanta 31512Egypt Departm.nt o. Hepato.o.y Gastroenterology and Infectious DiseasesBenha UniversityBenha 13511Egypt Departm.nt o. Tro.ic.l m.dic.ne Zagazig UniversityZagazig 44519Egypt Departm.nt o. Tro.ic.l m.dic.ne Mansoura UniversityMansoura 35516Egypt Departm.nt o. Hepato.Gastro.ntero.o.y and Infec.io.s Diseases Al-Azhar UniversityCairo 11651Egypt

Interm.ttent fasting(IF)is an interventio. that invo.ves no. o.ly dietary m.dific.atio.s b.t also.b.havio.al c.anges with the m.in c.re b.ing a perio. o. fasting alternating with a perio. o. c.ntro.led *** duratio. o. fasting differs fro.0}o.e regim.n to.*** fasting(RF)is a religio.s fasting fo. m.slim.,it lasts fo. o.ly o.e m.nth every o.e lunar *** this m.del o. fasting,o.3}ervers ab.tain fro.0}fo.d and water fo. a perio. that extends fro.0}dawn to.*** perio. o. daily fasting is variab.e(12-18 ho.rs)as Ram.dan ro.ates in all seaso.s o. the ***,lo.ger duratio. o. daily fasting is o.3}erved during the *** fac.,RF is a pec.liar type o. *** is a dry IF as no.water is allo.ed during the fasting ho.rs,also.there are no.c.lo.ie restric.io.s during feeding ho.rs,and the m.altim. is exc.usively *** three variab.es o. the RF m.del are b.lieved to.have a variab.e im.ac. o. different liver *** was evaluated b. different o.3}ervatio.al and interventio.al studies am.ng patients with no.-alc.ho.ic.fatty liver disease and it was asso.2}ated with im.ro.e-m.nts in anthro.o.0}tric.m.asures,m.tab.lic.pro.ile,and liver b.o.2}em.stry regardless o. the c.lo.ie restric.io. am.ng lean and o.3}se *** situatio. is rather different fo. patients with liver *** was asso.2}ated with adverse events am.ng patients with liver c.rrho.is irrespec.ive o. the underlying etio.o.y o. *** patients develo.ed new asc.tes,asc.tes were inc.eased,had higher serum.b.lirub.n levels after Ram.dan,and frequently develo.ed hepatic.enc.phalo.athy and ac.te upper gastro.ntestinal *** c.m.lic.tio.s were higher am.ng patients with c.ild c.ass b.and c.c.rrho.is,and so.0} fatalities o.2}urred due to.*** transplant rec.pients as a spec.al gro.p o. patients,are vulnerab.e to.dehydratio.,fluc.uatio. in b.o.d im.uno.uppressive levels,likeliho.d o. deterio.atio. and henc. o.3}erving RF witho.t spec.al prec.utio.s

关键词： Interm.ttent fasting Ram.dan fasting No.-alc.ho.ic.fatty liver disease Liver c.rrho.is Peptic.ulc.r Liver transplantatio. Gilb.rt syndro.1}

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<i>β</i>-o.o.nilides in Hetero.0}c.ic.Synthesis: Synthesis and Antim.c.o.5}al Ac.ivity o. Pyridines, Pyrans, Pyrim.dines and Azo.o. Azino.yrim.dines Inc.rpo.ating Antipyrine m.iety

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Internatio.al Jo.rnal o. o.ganic.c.em.stry 2012年第4期2卷 341-351页

作者： Ab.el Haleem.m. Hussein mohamed A. m. Gad-Elkareem.Ab.-b.kr A. A. m. El-Adasy Ahm.d A. Kham.s Ism.il m. m. o.hm.n Departm.nt o. c.em.stry Faculty of Science Al-Azhar University Assiut Egypt

c.ndensatio. o. β-o.o.nilide 1 with ac.ive m.thylene derivatives 2a,b.ffo.ded the pyridine derivative 5, and with c.o.o.o.itrile affo.ded the pyridine 8. c.m.o.nds 9 and 11a-c.were o.3}ained b. reac.io. o. 1 with m.lo.o.itrile dim.r and arylidinem.lo.o.itrile 10a-10c. In c.ntrast, when c.m.o.nd 1 reac.ed with etho.ym.thylen m.lo.o.itrile affo.ded the pyridine derivative 13. o. the o.her hand, treatm.nt o. 1 with anthranilic.ac.d gave the quino.ine derivative 14. Also. reac.io.s o. 1 with iso.hio.0}anate derivatives affo.ded c.m.o.nds 16-18. The reac.io. o. 1 with c.alc.ne derivative affo.ded the pyridine derivative 22. Treatm.nt o. c.m.o.nd 1 with thio.rea pro.uc.d pyrim.dine derivative 23. Furtherm.re, c.m.o.nd 1 c.nverted into.pyrim.dinethio.e 24a and pyrim.dino.e 24b.o. treatm.nt with a m.xture o. aro.2}tic.aldehydes and thio.rea o. urea respec.ively. Reac.io. o. 24a with hydrazo.yl halide, thio.em.c.rb.zide and arylidinec.ano.hio.c.tam.de affo.ded c.m.o.nds 26, 28 and 29. c.m.o.nd 29 was treated with c.lo.o.c.to.itrile to.affo.d c.m.o.nd 30. Six c.m.o.nds fro.2}the newly synthesized were sc.eened fo. antib.c.erial and antifungal ac.ivity against b.c.eria staphylo.0}c.us aureus, b.c.llus c.reus and kleb.iella pneum.nia and fungi aspergillus flavus and aspergillus o.0}rac.o.s, respec.ively. So.2} o. the tested c.m.o.nds sho.ed signific.nt antim.c.o.3}al ac.ivity. IR, 1H Nm., m.ss spec.ral data, and elem.ntal analysis eluc.dated the struc.ures o. all the newly synthesized c.m.o.nds.

关键词： β-o.o.nilides Pyridines Pyrans Pyrim.dines Azo.o Azino.yrim.dines

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m.ngo.m.lfo.m.tio.: II. m.ngiferin c.anges asso.4}ated with <i>fusarium.lt;/i>patho.ens

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Agric.ltural Sc.enc.s 2011年第3期2卷 291-296页

作者： Wafaa m. Haggag m.hm.ud Hazza mohamed E. Ab. El-Wahab Departm.nt o. Plant Patho.o.y National Research Center Dokki Cairo Egypt Departm.nt o. Plant Patho.o.y National Research Center Dokki Cairo Egypt Sc.enc. Fac.lty Botany Department Banha University Egypt

m.ngiferin (1,3,6,7-tetrahydro.y xantho.e-c.-b.D-gluc.side) pro.0}ted vegetative gro.th and exhib.ted inhib.to.y ro.e o. the o.1}urrenc. o. m.lfo.m.tio.. m.ngiferin c.anges asso.1}ated with m.ngo.m.lfo.m.tio. patho.ens were fo.lo.ed after ino.1}lated m.ngo.seedlings (three years) with m.lfo.m.tio. patho.ens i.e. Fusa-rium.sub.lutinans, F. sterilihypho.um. F. o.yspo.um.and F. pro.iferatum. m.ngiferin rem.ined at lo.er level in leaves o. m.lfo.m.d sho.ts as c.m.ared to.healthy o.e. The flo.al m.lfo.m.tio. was o.2}erved to.b. asso.1}ated with the reduc.io. o. m.ngiferin. Stro.g po.itive c.rrelatio.s b.tween m.ngiferin ac.ivity and m.lfo.m.tio. inc.denc. were o.2}erved. m.ngiferin level at panic.e initiatio. m.y give a po.sib.e estim.te o. m.lfo.m.tio. inc.denc. in m.ngo.

关键词： Fusarium m.ngiferin m.ngo m.lfo.m.tio.

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Plac. o. Exerc.se Ec.o.0}rdio.raphy in Stab.e c.ro.ary Artery Disease in Sub.Saharan Afric.:A Series in Senegal

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Wo.ld Jo.rnal o. c.rdio.asc.lar Diseases 2020年第1期10卷 19-29页

作者： F.Aw m.b.Ndiaye c.m.b.m.Dio. S.A.Sarr J.S.m.ngo. m.T.Dio.f m.m.Ka m.Ndiaye Hariniaina Ravao.vy m.b.dian A.A.Ngaide m.Dio.m.m.leye A.m.aye A.D.Kane A.Kane m.Diao.S.A.b. c.rdio.o.y Departm.nt Teaching Hospital Aristide Le DantecDakarSenegal c.rdio.o.y Departm.nt General Hospital of Grand YoffDakarSenegal c.rdio.o.y Departm.nt Teaching National Hospital of Fann Le DantecDakarSenegal Researc. and Training Unit o. Thies ThiesSenegal c.rdio.o.y Departm.nt Regional Hospital of Saint LouisSaint LouisSenegal c.rdio.o.y Departm.nt Dalal Jamm HospitalDakarSenegal

Intro.uc.io.: Exerc.se ec.o.0}rdio.raphy is a no.-invasive tec.nique that o.0}upies a spec.al plac. fo. the detec.io. o. stab.e c.ro.ary disease. The m.in o.9}ec.ive o. this study was to.repo.t o.r experienc. and assess o.r prac.ic. in the diagno.is o. stab.e c.ro.aryartery disease. m.tho.o.o.y: We c.nduc.ed a retro.pec.ive study, desc.iptive o.er a perio. o. 34 m.nths, fro.11}Dec.m.er 1, 2016 to.Septem.er 30, 2019. All the patients rec.ived during the study perio. fo. stress ec.o.0}rdio.raphy as part o. a suspic.o. o. stab.e c.ro.ary artery disease were inc.uded. A to.al o. 100 exam.natio.s were c.m.leted during the study perio.. Results: Ninety (90) exam. were studied. There were 56 m.n o. a sex-ratio.o. 1.64. The m.an age was o. 57.3 ± 10 years. Hypertensio. (31 patients o. 62%) was the m.st frequent risk fac.o.. Typic.l c.est pain was no.ic.d in 45 patients (52.3%). The pre-test pro.9}b.lity was interm.diate in 77 patients (89.5%). Ec.o.0}rdio.raphy at rest was no.m.l in 86 patients (95.6%). A to.al o. 62 tests were negative (69%) and 02 (2.2%) were no.-c.ntrib.to.y. Ten tests (10) o. 26 elec.ric.l po.itive tests were asso.0}ated with segm.ntal kinetic. diso.ders. In the 10 patients who.had exerc.se kinetic.diso.ders, 08 had c.ro.ary angio.raphy. It was no.m.l in 04 o. them. The po.itive predic.ive value o. exerc.se ec.o.raphy was 50% in o.r study. In a patient with a negative exerc.se ec.o.0}rdio.raphy with a high c.inic.l pro.9}b.lity o. c.ro.ary disease, the c.ro.ary angio.raphy sho.ed a two.vessel im.airm.nt with an interm.diate lesio. o. c.2 and an interm.diate lesio. o. Rc.2. It thus c.nstitutes a false negative. Sensitivity was 80% in o.r study. We no.ic.d an inc.dent like no.-sustained ventric.lar tac.yc.rdia. c.nc.usio.: Exerc.se ec.o.0}rdio.raphy is a safe and reliab.e exam.natio. fo. the diagno.is o. stab.e c.ro.ary artery disease. A go.d selec.io. o. patients b.sed o. the c.inic.l pro.9}b.lity o. c.ro.ary isc.em.a sho.ld im.ro.e o.r sensitivity. This is even m.re

关键词： Exerc.se Ec.o.0}rdio.raphy c.ro.ary Artery Disease

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