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Geographic integration of hepatitis C virus: A global threat

World Journal of Virology 2016年第4期5卷 170-182页

作者： mohamed A Daw Abdallah A El-Bouzedi mohamed O Ahmed Aghnyia A Dau mohamed m agnan Aisha m Drah Department of medical microbiology and Immunology Faculty of Medicine Clinical microbiology and microbial Epidemiology Acting Physician Internal Medicine Scientific Coordinator of Libyan National Surveillance Studies of Viral Hepatitis and HIV Department of Laboratory medicine Faculty of Biotechnology Department of microbiology and Parasitology Faculty of Veterinary Medicine Department of Surgery Tripoli Medical Centre Faculty of Medicine Department of Pharma-cology Faculty of Medical Technology Alga-bal Algarbi University and Faculty of Medicine

AIm To assess hepatitis C virus(HCV) geographic integration, evaluate the spatial and temporal evolution of HCV worldwide and propose how to diminish its burden. mETHODS A literature search of published articles was performed using Pub med, mEDLINE and other related databases up to December 2015. A critical data assessment and analysis regarding the epidemiological integration of HCV was carried out using the meta-analysis method. RESULTS The data indicated that HCV has been integrated immensely over time and through various geographical regions worldwide. The history of HCV goes back to 1535 but between 1935 and 1965 it exhibited a rapid, exponential spread. This integration is clearly seen in the geo-epidemiology and phylogeography of HCV. HCV integration can be mirrored either as intra-continental or trans-continental. migration, drug trafficking and HCV co-infection, together with other potential risk factors, have acted as a vehicle for this integration. Evidence shows that the geographic integration of HCV has been important in the global and regional distribution of *** HCV geographic integration is clearly evident and this should be reflected in the prevention and treatment of this ongoing pandemic.

关键词： Geo-epidemiology Integration Hepatitis C virus genotypes Geography Phylogeography

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A new technique for fault diagnosis in transformer insulating oil based on infrared spectroscopy measurements

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High Voltage 2024年第2期9卷 319-335页

作者： mohamed m.F.Darwish mohamed H.A.Hassan Nagat m.K.Abdel-Gawad matti Lehtonen Diaa-Eldin A.mansour Department of Electrical Engineering Faculty of Engineering at ShoubraBenha UniversityCairoEgypt Department of Electrical Engineering and Automation School of Electrical EngineeringAalto UniversityEspooFinland Department of Electrical Power Engineering Egypt-Japan University of Science and Technology(E-JUST)New Borg El-Arab CityEgypt Department of Electrical Power and machines Engineering Faculty of EngineeringTanta UniversityTantaEgypt

Condition monitoring of the insulating system within power transformers has a massive importance according to the electrical *** gas analysis(DGA)is frequently used for this ***,DGA lacks the necessary level of accuracy to identify all equipment faults,particularly in their initial stages of ***,it does not have the capability for real-time monitoring and relies on manual sampling and laboratory testing,causing potential delays in fault ***,the interpretation of DGA data necessitates specialised expertise,which may pose difficulties for smaller entities that have limited access to ***,the contribution of this research is to use infrared spectroscopy measurements as a new effective technique substituting the DGA method for fault diagnosis in insulating *** inception faults that were considered in this study were the electrical fault(discharges of high energy)and the thermal fault(300°Cmperaturemulation processes inside the laboratory for both types of inception ***,six samples of pure paraffinic mineral oil were taken to be degraded in the *** that,all of them besides another sample that were not subjected to any kind of faults were taken to be examined by Fourier transform infrared(FTIR)spectroscopy to obtain an overview of the oil's behaviour in each fault *** that,the FTIR analysis was initially verified utilising the DGA ***,for further affirmation,the dielectric dissipation factor(DDF)for all samples was *** the final analysis,the verification tests provide experimental evidence about the outperformance of this new optical technique in detecting the transformer's inception faults in addition to proving its potential for being a superior alternative to the well-known traditional diagnostic techniques.

关键词： fault diagnosis spectroscopy

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Robust malicious Executable Detection Using Host-Based machine Learning Classifier

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Computers, materials & Continua 2024年第4期79卷 1419-1439页

作者： Khaled Soliman mohamed Sobh Ayman m.Bahaa-Eldin Department of Computer and Systems Engineering Ain Shams UniversityCairo11517Egypt Department of Computer Engineering Technology ElSewedy University of TechnologyCairo44629Egypt

The continuous development of cyberattacks is threatening digital transformation endeavors worldwide and leadsto wide losses for various organizations. These dangers have proven that signature-based approaches are insufficientto prevent emerging and polymorphic attacks. Therefore, this paper is proposing a Robust malicious ExecutableDetection (RmED) using Host-based machine Learning Classifier to discover malicious Portable Executable (PE)files in hosts using Windows operating systems through collecting PE headers and applying machine learningmechanisms to detect unknown infected files. The authors have collected a novel reliable dataset containing 116,031benign files and 179,071 malware samples from diverse sources to ensure the efficiency of RmED *** most effective PE headers that can highly differentiate between benign and malware files were selected totrain the model on 15 PE features to speed up the classification process and achieve real-time detection formalicious executables. The evaluation results showed that RmED succeeded in shrinking the classification timeto 91 milliseconds for each file while reaching an accuracy of 98.42% with a false positive rate equal to 1.58. Inconclusion, this paper contributes to the field of cybersecurity by presenting a comprehensive framework thatleverages Artificial Intelligence (AI) methods to proactively detect and prevent cyber-attacks.

关键词： Portable executable malware intrusion detection cybersecurity zero-day threats Host IntrusionDetection System(HIDS) machine learning Anomaly-based Intrusion Detection System(AIDS) deep learning

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Comparative study between three carbonaceous nanoblades and nanodarts for antimicrobial applications

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Journal of Environmental Sciences 2024年第2期136卷 594-605页

作者： mohamed S.Selim Ahmed m.Azzam mohamed A.Shenashen Shimaa A.Higazy Bayaumy B.mostafa Sherif A.El-Safty National Institute for materials Science(NImS) 1-2-1 SengenTsukuba-ShiIbaraki-Ken 305-0047Japan Petroleum Application Department Egyptian Petroleum Research InstituteNasr City 11727Egypt Department of Environmental Research Theodor Bilharz Research InstituteGizaEgypt

The design of nanostructured materials occupies a privileged position in the development and management of affordable and effective technology in the antibacterial ***,we discuss the antimicrobial properties of three carbonaceous nanoblades and nanodarts materials of graphene oxide(GO),reduced graphene oxide(RGO),and single-wall carbon nanotubes(SWCNTs)that have a mechano-bactericidal effect,and the ability to piercing or slicing bacterial *** demonstrate the significance of size,morphology and composition on the antibacterial activity mechanism,the designed nanomaterials have been *** minimum inhibitory concentration(mIC),standard agar well diffusion,and transmission electron microscopy were utilized to evaluate the antibacterial activity of GO,RGO,and *** on the evidence obtained,the three carbonaceous materials exhibit activity against all microbial strains tested by completely encapsulating bacterial cells and causing morphological disruption by degrading the microbial cell membrane in the order of RGO>GO>*** of the external cell wall structure and outer membrane proteins,the synthesized carbonaceous nanomaterials exhibited higher antibacterial activity against Gram-positive bacterial strains than Gram-negative and fungal *** had the lowest mIC values(0.062,0.125,and 0.25 mg/mL against ***,***,and ***,respectively),as well as minimum fungal concentrations(0.5 mg/mL for both *** and ***).At 12 hr,the cell viability values against tested microbial strains were completely *** lysis and death occurred as a result of severe membrane damage caused by microorganisms perched on RGO *** work gives an insight into the design of effective graphene-based antimicrobial materials for water treatment and remediation.

关键词： Antimicrobial properties Nanoblades mechano-bactericidal effect RGO nanosheets Gram-positive bacteria Cell viability

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Dysprosium oxide,alumina,and graphene oxide reinforced polycaprolactone thin films:Thermal stability,morphology,and cell viability

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Journal of Rare Earths 2024年第7期42卷 1337-1343,I0005页

作者： mohamed Tharwat Elabbasy mohamed R.Atteya mai A.Samak mousa Abdelrahman Tahani Almahmoud m.A.El-morsy A.A.menazea m.F.H.Abd El-Kader Department of Public Health College of Public Health and Health InformaticsUniversity of Ha'ilHa'il2440Saudi Arabia Food Control Department Faculty of Veterinary MedicineZagazig UniversityZagazig44519Egypt Department of Physical Therapy College of Applied Medical SciencesUniversity of Ha'ilHa'ilSaudi Arabia Department of Histology and Cell Biology Faculty of MedicineZagazig UniversityZagazig44519Egypt College of Nursing University of Ha'ilHa'ilSaudi Arabia College of Science and Humanities in Al-Kharj Physics DepartmentPlasma Technology and Material Science UnitPrince Sattam Bin Abdulaziz UniversityAl-kharj11942Saudi Arabia Physics Department Faculty of ScienceUniversity of DamiettaNew Damietta34517Egypt Spectroscopy Department Physics Research InstituteNational Research CentreDokki12622GizaEgypt Biophysics Department Faculty of ScienceCairo UniversityGizaEgypt

Developing a biomaterial for wound healing applications is still a ***,dysprosium oxide(Dy_(2)O_(3)),aluminum oxide(Al_(2)O_(3)),and graphene oxide(GO)were embedded in cast films based on polycaprolactone(PCL)to be examined for wound dressing *** techniques were used to characterize the fabricated films including X-ray diffraction(XRD),Fourier transform infrared spectroscopy(FTIR),Raman,and scanning electron microscopy(SEm),besides their biological *** thermogravimetric analysis(TGA)exhibits high thermal stability as the scaffold weight decreases slightly to 98.6%after raising the temperature from room temperature to 280℃.The cell viability was investigated and it is shown that the viable cells grow up to approximately 93%at 75μg/***,the cell attachment shows excellent behavior as the cells attach on most of the surface of the modified PCL which shows high biocompatibility.

关键词： Wound healing Polycaprolactone Dy_(2)O_(3) Al_(2)O_(3) Biocompatible Rare earths

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Geochemistry of island arc assemblage in the Eastern Desert of Egypt and the role of Pan-African magmatism in crustal growth of the Arabian–Nubian Shield:A review

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Acta Geochimica 2024年第3期43卷 588-622页

作者： Abdel-Aal mAbdel-Karim mohamed mHamdy Adel A.Surour Geology Department Faculty of ScienceZagazig UniversityZagazig 44519Egypt Geology Department Faculty of ScienceTanta UniversityTanta 31527Egypt Department of Geological Sciences Faculty of ScienceNew Galala City 43511Egypt Geology Department Faculty of ScienceCairo UniversityGiza 12613Egypt

Neoproterozoic island arc assemblage of the Arabian–Nubian Shield(ANS)in the Eastern Desert(ED)of Egypt comprises juvenile suites of metavolcanics(mV),large amounts of meta-sedimentary rocks(mS),and voluminous metagabbros-diorites(mGD)and syn-tectonic intrusions of older granitoids(OG).We report here the updates of these four rock units in terms of classification,distribution,chemical characteristics,geodynamic evolution,metamorphism,and *** addition,we discuss these integrated data to elucidate a reasonable and reliable model for crustal evolution in the *** main features of these rock units indicate their relation to each other and the geodynamic environment dominated by early immature oceanic island arcs to primitive continental *** information of the island arc metavolcanic and plutonic rocks(gabbros,diorites,tonalites,and granodiorites)furnish evidence of the genetic *** include proximity and a coeval nature in the field;all protolith magmas are subalkaline in nature following calc-alkaline series with minor tholeiitic affinities;common geochemical signature of the arc rocks and subduction-related magmatism;their similar enrichment in LREEs;and similar major element compositions with mafic melts derived from metasomatized mantle *** volcano-sedimentary and the OG rocks underwent multiphase deformation events whereas the mGD complexes deformed *** on the magmatic,sedimentological,and metamorphic evolutions constrained by geochronological data as well as the progressive evolutionary trend from extensional to compressional regimes,a possible gradual decrease in the subducted slab dip angle is the most infl uential in any geodynamic model for arc assemblage in the ED of Egypt.

关键词： Island arc assemblage magmatism Crustal growth Neoproterozoic Arabian–Nubian Shield Eastern Desert Egypt

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Genetic Variability and Phenotypic Correlations Study among Grain Quality Traits and mineral Elements Concentrations in Colored and Non-Colored Rice (Oryza sativa L.)

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1733-1748页

作者： Adel A.Rezk mohamed m.El-malky Heba I.mohamed Hossam S.El-Beltagi Agricultural Biotechnology Department College of Agricultural and Food ScienceKing Faisal UniversityAl-Ahsa31982Saudi Arabia Plant Pathology Research Institute Agriculture Research CenterGiza12619Egypt Rice Research and Training Center Field Crop Research InstituteAgriculture Research Center33717Egypt Biological and Geological Sciences Department Faculty of EducationAin Shams UniversityCairo11511Egypt Biochemistry Department Faculty of AgricultureCairo UniversityGiza12613Egypt

Twenty-four rice genotypes were examined to assess genetic variability,heritability,and correlations for seven-grain quality traits,eight nutritional elements,and *** revealed signiﬁcant differences for the quality traits *** every trait under study,the phenotypic coefﬁcient of variation was higher than the correspon-dence genotypic coefﬁcient of *** in a broad sense varied from 29.75%for grain length to 98.31%for the elongation *** percentage recovery had a highly signiﬁcant positive correlation with milling and head rice ***,milling percentage had a highly positive correlation with head rice *** amylose percentage,all the genotypes belonged to low amylose except the Hassawi-1 variety,which had intermediate amylose *** nutrition contents of magnesium(mg),sodium(Na),potas-sium(K),calcium(Ca),copper(Cu),manganese(mn),zinc(Zn),iron(Fe),or protein percentage gave different variations for 24 rice genotypes under all the nutritional *** the 24 genotypes,ten rice genotypes–HighNutrient-1,HighNutrient-2,HighNutrient-9,HighNutrient-8,HighNutrient-3,Hassawi-2,HighNutrient-7,HighNutrient-6,Hassawi-1,and HighNutrient-4–had the highest heist value for all nutritional and protein con-tents,and could be used as a donor to improving new *** was a positive and signiﬁcant correlation between magnesium mg,K,Zn and ***,K had a positive correlation with zinc Zn,Fe,and protein *** analysis was divided into two groups:theﬁrst group included all genotypes rich in nutri-ents,while the remaining genotypes with low nutritional content were included in the second group.

关键词： Amylose cluster analysis genotypes grain quality mineral nutrition rice

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Assessment of plant diversity of endemic species of the Saharo-Arabian region in Egypt

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Journal of Arid Land 2024年第7期16卷 1000-1021,I0002-I0044页

作者： Asmaa S ABO HATAB Yassin m AL-SODANY Kamal H SHALTOUT Soliman A HAROUN mohamed m EL-KHALAFY Botany and microbiology Department Faculty of ScienceKafrelsheikh UniversityKafrelsheikh 33511Egypt Botany Department Faculty of ScienceTanta UniversityTanta 31527Egypt

Savanna, semi-deserts, and hot deserts characterize the Saharo-Arabian region, which includes morocco, mauretania, Algeria, Tunisia, Libya, Egypt, Palestine, Kuwait, Saudi Arabia, Qatar, Bahrain, the United Arab Emirates, Oman, Yemen, southern Jordan, Syria, Iraq, Iran, Afghanistan, Pakistan, and northern India. Its neighboring regions, the Sudano-Zambezian region belonging to the Paleotropical Kingdom and the mediterranean and Irano-Turanian regions included in the Holarctic Kingdom, share a large portion of their flora with the Saharo-Arabian region. Despite the widespread acknowledgment of the region's global importance for plant diversity, an up to date list of the Saharo-Arabian endemics is still unavailable. The available data are frequently insufficient or out of date at both the whole global and the national scales. Therefore, the present study aims at screening and verifying the Saharo-Arabian endemic plants and determining the phytogeographical distribution of these taxa in the Egyptian flora. Hence, a preliminary list of 429 Saharo-Arabian endemic plants in Egypt was compiled from the available literature. Indeed, by excluding the species that were recorded in any countries or regions outside the Saharo-Arabian region based on different literature, database reviews, and websites, the present study has reduced this number to 126 taxa belonging to 87 genera and 37 families. Regarding the national geographic distribution, South Sinai is the richest region with 83 endemic species compared with other eight phytogeographic regions in Egypt, followed by the Isthmic Desert(the middle of Sinai Peninsula, 53 taxa). Sahara regional subzone(SS1) distributes all the 126 endemic species, Arabian regional subzone(SS2) owns 79 taxa, and Nubo-Sindian subzone(SS3) distributes only 14 endemics. Seven groups were recognized at the fourth level of classification as a result of the application of the two-way indicator species analysis(TWINSPAN) to the Saharo-Arabian endemic sp

关键词： endemism phytogeographical regions Saharo-Arabian floristic region Egyptian flora plant diversity two-way indicator species analysis(TWINSPAN)

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A statistical approach to enhance the productivity of Streptomyces baarensis mH-133 for bioactive compounds

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Synthetic and Systems Biotechnology 2024年第2期9卷 196-208页

作者： mohamed H.Kalaba Gamal m.El-Sherbiny Osama m.Darwesh Saad A.moghannem Botany and microbiology Department Faculty of Science(Boys)Al-Azhar UniversityCairo 11884Egypt Agricultural microbiology Department National Research CentreDokkiCairoEgypt

The goal of this study was to use statistical optimization to change the nutritional and environmental conditions so that Streptomyces baarensis mH-133 could make more active *** trials were used to screen for critical variables influencing productivity using the Placket-Burman Design *** mH-133 is significantly influenced by elicitation,yeast extract,inoculum size,and incubation period in terms of antibacterial activity.A total of 27 experimental trials with various combinations of these factors were used to carry out the response surface technique using the Box-Behnken *** analyses revealed that the model was highly significant(pmination(R2)of ***,the model predicted that the response as inhibition zone diameter would reach a value of 27 *** optimal conditions,*** mH-133 produced 18.0 g of crude extract to each 35L and was purified with column *** active fraction exhibiting antibacterial activity was characterized using spectroscopic *** mIC and mBC values varied between 37.5 and 300μg/ml and 75 and 300μg/ml,*** conclusion,the biostatistical optimization of the active fraction critical variables,including environmental and nutritional conditions,enhances the production of bioactive molecules by Streptomyces species.

关键词： S.baarensis mH-133 Placket-Burman designBox-Behnken design ESKAPE Antibacterial activity

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Enhancing fault-clearing algorithm for renewable-energy-based distribution systems using artificial neural networks

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Clean Energy 2024年第5期8卷 97-116页

作者： Rania G.mohamed m.A.Ebrahim Shady H.E.Abdel Aleem Electrical Engineering Department Institute of Aviation Engineering and TechnologyGiza12658Egypt Electrical Engineering Department Faculty of Engineering at ShoubraBenha UniversityCairo11629Egypt

Integrating small and large-scale photovoltaic(PV)solar systems into electrical distribution systems has become mandatory due to increased electricity bills and the concern for limiting greenhouse ***,the reliable and efficient operation of PV-based distribution systems can be confronted by the intermittence and high variability of solar sources and their consequential *** this regard,this article suggests a moderated fault-clearing strategy based on the incremental conductance–maximum power point tracking(IC–mPPT)technique and artificial neural networks(ANNs)to enhance fault detection,localization,and restoration pro-cesses in PV-based distribution *** proposed strategy leverages IC–mPPT to ensure optimal power generation from the PV solar system,even in the presence of *** tracking the maximum power point,the algorithm maintains the performance of the system and mitigates against the impact of faults on the output ***,an ANN is employed to improve fault detec-tion and localization *** developed ANN-based moderated fault-clearing strategy is trained using historical data and fault scenarios,enabling it to recognize fault patterns and make informed decisions through extensive simulations and comparisons with traditional fault-clearing *** accomplish this study,benchmarks in PV-based distribution systems are constructed and em-ployed using the mATLAB®/Simulink®software ***,to validate the efficacy of the developed ANN-based moderated fault-clearing strategy,a real case study of a 1-mW PV-based distribution system in an industrial field located in Giza governorate,Egypt,is tested and *** obtained results demonstrate the effectiveness of the IC–mPPT and ANN-based moderated fault-clearing strategy in achieving faster fault detection,precise fault localization,and efficient restoration in PV solar-based dis-tribution systems while preserving maximum power extraction under small and larg

关键词： photovoltaic solar systems fault-clearing algorithm incremental conductance renewable energy artificial neural network maximum power point tracking

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