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Phytoconstituents Profiling of Indigenous Herbal Drugs and Its in vitro Microbial,in Silico Biological Examination against Severe Acute Respiratory Syndrome Coronavirus 2

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World Journal of Traditional Chinese Medicine 2024年第1期10卷 121-136页

作者： T.H.mohamed Ahadu Shareef Mmohamed Divan Masood Irfan Navabshan MSaiyad Musthafa Department of Chemistry The New College(Autonomous)Affiliated to the University of MadrasChennaiTamil NaduIndia School of Computer Applications B.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil NaduIndia Crescent School of Pharmacy B.S.Abdur Rahman Crescent Institute of Science and TechnologyChennaiTamil NaduIndia Department of Zoology The New College(Autonomous)Affiliated to the University of MadrasChennaiTamil NaduIndia

Background:Habb-E-Shifa,Hamdard Sualin,and Hamdard Joshanda traditional herbal medicines may promote host resistance against infection by bacteria,viruses,and fungi which are easily accessible at inexpensive with no *** herbal medicines are used to cure sore throat,cough,fever,lung cancer,and asthma patients in developing South Asian *** traditional herbal medicines acted a crucial role in the prevention and control of coronavirus disease 2019(COVID-19).Aims and Objectives:This research article aimed at conducting phytochemistry,antimicrobial activity,COVID-19 docking and some spectroscopic(Infrared,Ultraviolet,13C-Nuclear Magnetic Resonance(13C-NMR),1H-NMR,and Mass Spectra)characterizations of the polyherbal drugs were carried ***,In-vitro and In-silico analyses were performed to measure activity against *** Performance-Liquid Chromatography(HPLC),Gas Chromatography-Mass Spectrometry(GC-MS),antimicrobial,and docking studies were carried *** preliminary phytochemical assay and bioactive compounds were screened using HPLC and *** study is an attempt to assess the promising effects of selected polyherbal indigenous drugs such as Habb-E-Shifa,Hamdard Sualin,and Hamdard Joshanda phytoconstituents against the severe acute respiratory syndrome coronavirus-2(SARS-Co V-2).Materials and Methods:The extract of the selected polyherbal formulations showed high-to-moderate preventive effects on the growth inhibition in the pathogenic bacterium,namely Streptococcus oralis,Staphylococcus aureus,Propionibacterium acnes,Pseudomonas aeruginosa,Escherichia coli,and Proteus vulgaris,and three fungal Candida albicans,Aspergillus fumigatus,and Aspergillus *** docking study evaluates the pharmacological activity of bioactive chemical compounds with SARS-Co V-2 NSP5(PDB ID:7nxh)and SARS-Co V-2 Omicron spike protein with human angiotensin-converting enzyme 2(ACE-2)(PDB ID:7wk6).Results:In this study,for the first time,we at

关键词： Antimicrobial herbal drug Omicron and coronavirus disease 2019 phytochemicals spectroscopic

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Geochemistry of island arc assemblage in the Eastern Desert of Egypt and the role of Pan-African magmatism in crustal growth of the Arabian–Nubian Shield:A review

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Acta Geochimica 2024年第3期43卷 588-622页

作者： Abdel-Aal MAbdel-Karim mohamed MHamdy Adel A.Surour Geology Department Faculty of ScienceZagazig UniversityZagazig 44519Egypt Geology Department Faculty of ScienceTanta UniversityTanta 31527Egypt Department of Geological Sciences Faculty of ScienceNew Galala City 43511Egypt Geology Department Faculty of ScienceCairo UniversityGiza 12613Egypt

Neoproterozoic island arc assemblage of the Arabian–Nubian Shield(ANS)in the Eastern Desert(ED)of Egypt comprises juvenile suites of metavolcanics(MV),large amounts of meta-sedimentary rocks(MS),and voluminous metagabbros-diorites(MGD)and syn-tectonic intrusions of older granitoids(OG).We report here the updates of these four rock units in terms of classification,distribution,chemical characteristics,geodynamic evolution,metamorphism,and *** addition,we discuss these integrated data to elucidate a reasonable and reliable model for crustal evolution in the *** main features of these rock units indicate their relation to each other and the geodynamic environment dominated by early immature oceanic island arcs to primitive continental *** information of the island arc metavolcanic and plutonic rocks(gabbros,diorites,tonalites,and granodiorites)furnish evidence of the genetic *** include proximity and a coeval nature in the field;all protolith magmas are subalkaline in nature following calc-alkaline series with minor tholeiitic affinities;common geochemical signature of the arc rocks and subduction-related magmatism;their similar enrichment in LREEs;and similar major element compositions with mafic melts derived from metasomatized mantle *** volcano-sedimentary and the OG rocks underwent multiphase deformation events whereas the MGD complexes deformed *** on the magmatic,sedimentological,and metamorphic evolutions constrained by geochronological data as well as the progressive evolutionary trend from extensional to compressional regimes,a possible gradual decrease in the subducted slab dip angle is the most infl uential in any geodynamic model for arc assemblage in the ED of Egypt.

关键词： Island arc assemblage Magmatism Crustal growth Neoproterozoic Arabian–Nubian Shield Eastern Desert Egypt

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Synergistic Swarm Optimization Algorithm

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Computer Modeling in Engineering & Sciences 2024年第6期139卷 2557-2604页

作者： Sharaf Alzoubi Laith Abualigah mohamed Sharaf Mohammad Sh.Daoud Nima Khodadadi Heming Jia Faculty of Computer Sciences and Informatics Amman Arab UniversityAmman11953Jordan Computer Science Department Al Al-Bayt UniversityMafraq25113Jordan Department of Electrical and Computer Engineering Lebanese American UniversityByblos13-5053Lebanon Hourani Center for Applied Scientific Research Al-Ahliyya Amman UniversityAmman19328Jordan MEU Research Unit Middle East UniversityAmman11831Jordan Applied Science Research Center Applied Science Private UniversityAmman11931Jordan School of Computer Sciences Universiti Sains MalaysiaPulau Pinang11800Malaysia School of Engineering and Technology Sunway University MalaysiaPetaling Jaya27500Malaysia Department of Industrial Engineering College of EngineeringKing Saud UniversityP.O.Box 800Riyadh11421Saudi Arabia College of Engineering Al Ain UniversityAbu Dhabi112612United Arab Emirates Department of Civil and Architectural Engineering University of MiamiCoral Gables1251USA School of Information Engineering Sanming UniversitySanming365004China

This research paper presents a novel optimization method called the Synergistic Swarm Optimization Algorithm(SSOA).The SSOA combines the principles of swarmintelligence and synergistic cooperation to search for optimal solutions efficiently.A synergistic cooperation mechanism is employed,where particles exchange information and learn from each other to improve their search *** cooperation enhances the exploitation of promising regions in the search space while maintaining exploration ***,adaptive mechanisms,such as dynamic parameter adjustment and diversification strategies,are incorporated to balance exploration and *** leveraging the collaborative nature of swarm intelligence and integrating synergistic cooperation,the SSOAmethod aims to achieve superior convergence speed and solution quality performance compared to other optimization *** effectiveness of the proposed SSOA is investigated in solving the 23 benchmark functions and various engineering design *** experimental results highlight the effectiveness and potential of the SSOA method in addressing challenging optimization problems,making it a promising tool for a wide range of applications in engineering and *** codes of SSOA are available at:https://***/matlabcentral/fileexchange/153466-synergistic-swarm-optimization-algorithm.

关键词： Synergistic swarm optimization algorithm optimization algorithm metaheuristic engineering problems benchmark functions

MOALG: A Metaheuristic Hybrid of Multi-Objective Ant Lion Optimizer and Genetic Algorithm for Solving Design Problems

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Computers, Materials & Continua 2024年第3期78卷 3489-3510页

作者： Rashmi Sharma Ashok Pal Nitin Mittal Lalit Kumar Sreypov Van Yunyoung Nam mohamed Abouhawwash Department of Mathematics Chandigarh UniversityGharuanMohali140413India Deaprtment of Industry 4.0 Shri Vishwakarma Skill UniversityPalwal121102India Department of ICT Convergence Soonchunhyang UniversityAsan31538Korea Department of Computational Mathematics Science and Engineering(CMSE)College of EngineeringMichigan State UniversityEast LansingMI 48824USA Department of Mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt

This study proposes a hybridization of two efficient algorithm’s Multi-objective Ant Lion Optimizer Algorithm(MOALO)which is a multi-objective enhanced version of the Ant Lion Optimizer Algorithm(ALO)and the Genetic Algorithm(GA).MOALO version has been employed to address those problems containing many objectives and an archive has been employed for retaining the non-dominated *** uniqueness of the hybrid is that the operators like mutation and crossover of GA are employed in the archive to update the solutions and later those solutions go through the process of MOALO.A first-time hybrid of these algorithms is employed to solve multi-objective *** hybrid algorithm overcomes the limitation of ALO of getting caught in the local optimum and the requirement of more computational effort to converge *** evaluate the hybridized algorithm’s performance,a set of constrained,unconstrained test problems and engineering design problems were employed and compared with five well-known computational algorithms-MOALO,Multi-objective Crystal Structure Algorithm(MOCryStAl),Multi-objective Particle Swarm Optimization(MOPSO),Multi-objective Multiverse Optimization Algorithm(MOMVO),Multi-objective Salp Swarm Algorithm(MSSA).The outcomes of five performance metrics are statistically analyzed and the most efficient Pareto fronts comparison has been *** proposed hybrid surpasses MOALO based on the results of hypervolume(HV),Spread,and *** primary objective of developing this hybrid approach has been achieved *** proposed approach demonstrates superior performance on the test functions,showcasing robust convergence and comprehensive coverage that surpasses other existing algorithms.

关键词： Multi-objective optimization genetic algorithm ant lion optimizer metaheuristic

Thermal performance of domed roof in air-conditioned spaces

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Energy and Built Environment 2024年第2期5卷 270-287页

作者： Ibrahim Reda Raouf N.AbdelMessih mohamed Steit Ehab M.Mina Mechanical Power Engineering Faculty of EngineeringAin Shams University1 El-Sarayat St.Cairo 11517Egypt Architectural Engineering Faculty of EngineeringAin Shams UniversityCairoEgypt

Due to their thermal performance,domed roofs are one of the passive solutions that affect energy consumption in *** thermal performance of domed roofs has been investigated in many naturally ventilated ***,few studies have discussed their performance in conditioned ***,this study introduces a computational comparison between domed and flat roofs to investigate their impact on thermal comfort inside a conditioned *** an earlier stage,field measurements were carried out inside a Bahraini mosque to acquire its indoor air conditions during the summer period of 2021,in addition to validating the computational *** findings of this study confirm that,under mechanical cooling conditions,the flat roof offers a lower indoor temperature than the domed roof by 0.4℃and 0.1℃for open and closed doors,***,the air velocity is lower by approximately 0.01 m/s for both door *** overall PMV values of the flat roof are also lower by 0.07 and 0.01,while the PPD values are lower by 0.20,and 0.34 for open and closed doors,*** on these small differences,it can be concluded that the thermal performance of both roofing systems behaves equally in conditioned ***,the air patterns are substantially different,the overall thermal performance is *** similarity drives building designers to rethink the thermal performance of the domed roofs in air-conditioned spaces with such a hot climate,regardless of their aesthetic and acoustical behaviour.

关键词： Thermal comfort Computational fluid dynamics(CFD) Predicted mean vote(PMV)and predicted percentage dissatisfied(PPD) Domed roof Flat roof

Intravesical instillation of platelet-rich plasma for treatment of interstitial cystitis/bladder pain syndrome:A pilot study

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Current Urology 2024年第1期18卷 49-54页

作者： Ahmed S.El Hefnawy mohamed Attya Ahmed Hasan Esam El Sawy mohamed Abdel-Razik Nasr El-Tabey Mansoura Urology and Nephrology Center Faculty of MedicineMansoura UniversityMansouraEgypt

Objective:The aim of this study was to evaluate the feasibility of intravesical instillation of platelet-rich plasma(PRP)to treat interstitial cystitis/bladder pain syndrome(IC/BPS).Materials and methods:Twenty PRP samples were tested in vitro for stability after exposure to urine samples with different pH.A pilot study involving 21 female patients with IC/BPS was conducted,and 6 weekly doses of autologous PRP(50 mL)were *** were followed up at the 2nd,4th,8th,and 12th weeks after terminating *** primary endpoint was the visual analog scale(VAS)for pain,and the secondary endpoints included the IC symptom index,IC problem index of the O'Leary-Sant questionnaire and global response assessment,urine culture,and *** was defined as a reduction in VAS by 30%or more compared with basal level,and adverse events were ***:The mean±SD of VAS was significantly reduced compared with basal level(4.4±2.6 vs.8.8±1.1,respectively,p=0.001).Meanwhile,80%of cases were considered successful,with a 50.1%reduction in the mean score compared with the basal *** mean±SD of IC symptom index and IC problem index significantly improved compared with the basal *** response assessment was markedly,moderately,and slightly improved in 2(10%),10(50%),and 5(25%)patients,respectively,and showed no change in 3(15%).Three patients had positive urine cultures at follow-up,but 1 withdrew after 2 sessions because of a lack of ***:Repeated intravesical instillation of PRP could be considered an effective and safe approach for treating IC/BPS.

关键词： Bladder pain syndrome Interstitial cystitis Platelet-rich plasma

The effectiveness of physical activity interventions on blood pressure in children and adolescents:A systematic review and network meta-analysis

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Journal of Sport and Health Science 2024年第5期13卷 699-708页

作者： mohamed A.Hassan Wanjiang Zhou Mingyi Ye Hui He Zan Gao School of Kinesiology University of Minnesota-Twin CitiesMinneapolisMN 55455USA Department of Methods and Curriculum Physical Education College for MenHelwan UniversityCairo 12552Egypt China Institute of Sport and Health Science Beijing Sport UniversityBeijing 100084China Department of Kinesiology Recreationand Sport StudiesUniversity of TennesseeKnoxvilleTN 37996USA

Background:High blood pressure(BP)is a major contributor to mortality and cardiovascular *** the known benefits of exercise for reducing BP,it is crucial to identify the most effective physical activity(PA)*** systematic review and network meta-analysis(NMA)aimed to evaluate the available evidence on the effectiveness of various PA interventions for reducing BP and to determine their hierarchy based on their impact on ***:A search of PubMed,SPORTDiscus,PsycINFO,Web of Science,CINAHL,Cochrane,and Eric databases was conducted up to December 2022 for this systematic review and *** controlled trials and quasi-experimental studies targeting healthy children and adolescents aged 6-12 years old were included in this *** studies that compared controlled and intervention groups using PA or exercise as the major influence were *** followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)*** independent investigators performed the literature screening,data extraction,and risk of bias *** used Bayesian arm-based NMA to synthesize the *** primary outcomes were systolic BP and diastolic *** calculated the mean differences(MDs)in systolic BP and diastolic BP before and after *** treatment differences were estimated using NMA and random-effect ***:We synthesized 27 studies involving 15,220 children and *** combined with nutrition and behavior change was the most effective intervention for reducing both systolic BP and diastolic BP(MD=-8.64,95%credible interval(95%CI):-11.44 to-5.84;MD=-6.75,95%CI:-10.44 to-3.11),followed by interventions with multiple components(MD=-1.39,95%CI:-1.94 to-0.84;MD=-2.54,95%CI:-4.89 to-0.29).Conclusion:Our findings suggest that PA interventions incorporating nutrition and behavior change,followed by interventions with multiple components,are most effective for reducing both systolic BP and diastolic BP

关键词： Children Diastolic blood pressure Physical activity Systolic blood pressure

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Investigating and predicting the role of photovoltaic, wind, and hydrogen energies in sustainable global energy evolution

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Global Energy Interconnection 2024年第4期7卷 429-445页

作者： Mahmood Swadi Dheyaa Jasim Kadhim mohamed Salem Firas Mohammed Tuaimah Ammar SabriMajeed Ali Jawad Alrubaie Department of Electrical Engineering College of EngineeringUniversity of BaghdadBaghdad 10001Iraq Libyan Authority for Scientific Research Tripoli 80045Libya School of Electrical and Electronic Engineering Universiti Sains Malaysia(USM)Nibong Tebal 14300PenangMalaysia Continuing Education Center University of BaghdadBaghdad 10001Iraq Al-Furat Al-Awsat Technical University AL-Mussaib Technical CollegeBabylonIraq

The global shift toward next-generation energy systems is propelled by the urgent need to combat climate change and the dwindling supply of fossil *** review explores the intricate challenges and opportunities for transitioning to sustainable renewable energy sources such as solar,wind,and *** transition economically challenges traditional energy sectors while fostering new industries,promoting job growth,and sustainable economic *** transition to renewable energy demands social equity,ensuring universal access to affordable energy,and considering community *** environmental benefits include a significant reduction in greenhouse gas emissions and a lesser ecological *** study highlights the rapid growth of the global wind power market,which is projected to increase from$112.23 billion in 2022 to$278.43 billion by 2030,with a compound annual growth rate of 13.67%.In addition,the demand for hydrogen is expected to increase,significantly impacting the market with potential cost reductions and making it a critical renewable energy source owing to its affordability and zero *** 2028,renewables are predicted to account for 42%of global electricity generation,with significant contributions from wind and solar photovoltaic(PV)technology,particularly in China,the European Union,the United States,and *** developments signify a global commitment to diversifying energy sources,reducing emissions,and moving toward cleaner and more sustainable energy *** review offers stakeholders the insights required to smoothly transition to sustainable energy,setting the stage for a resilient future.

关键词： Next energy Renewable energy Sustainability Environmental benefits Economic opportunities

Evaluation of the versatility of perforators-enhanced rhomboid flap technique for ischial sores reconstruction

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第2期6卷 65-71页

作者： Waleed Aldabaany Ashraf Hussein Elghamry Montaser Hosny mohamed Yassin Department of Plastic Surgery Faculty of Medicine Fayoum University

Background: Prolonged pressure on the skin known as pressure sores, can cause frequent injuries to the skin and underlying tissues. However, several prevention approaches, including non-surgical and surgical management,are available. In flap surgery for pressure sores, a variety of flap types may be used; each offers certain benefits and some incidences of complications and recurrence. This study evaluated the versatility of the perforatorenhanced rhomboid flap technique for ischial sore ***: This prospective study was conducted in the Plastic Surgery Department of Fayoum University *** perforator-enhanced rhomboid flap technique was employed in 20 patients with ischial pressure sores who failed to respond to conservative treatment. A proper history was obtained and a preoperative arterial duplex was performed to determine the site of the prominent perforators for their preservation at the base of the *** follow-ups and evaluations were ***: The mean age of the study group was 43.7 ± 13.1, ranging from 19 to 65 years. Moreover, 80% of the participants were males while 20% were female. The main etiology of the sores was paraplegia in 45% of *** mean surface area of sores was 24.8 ± 6.3 cm2. In 75% of cases, the color match of the flap was rated as excellent. Similarly, 70% of the patients rated flap thickness as excellent. In 55% of the cases, the scar appearance was deemed excellent. Overall satisfaction was reported as excellent by 40% of the patients, while only 5% reported poor satisfaction. Approximately, 10% of the cases were identified with seroma, and 30% had wound dehiscence of a mean size of 1.33 ± 0.98 cm and required around 6.8 ± 1.9 weeks to ***: The perforator-enhanced rhomboid flap technique is a versatile method for reconstructing ischial pressure sores owing to its technical ease, short operative time, reliable vascularity, aesthetic outcome, matching skin color, and short recov

关键词： Ischial pressure sores Perforators-enhanced rhomboid flaps Reconstruction