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A Multidisciplinary Approach to Mapping Potential Urban Development Zones in Sinai Peninsula, Egypt Using Remote Sensing and GIS

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Journal of Geographic Information System 2013年第6期5卷 567-583页

作者： Hala A. Effat mohamed N. hegazy Division of Geological Applications and Mineral Resources National Authority for Remote Sensing and Space Sciences NARSS Cairo Egypt Environmental Studies and Land Use Department National Authority for Remote Sensing and Space Sciences NARSS Cairo Egypt

One of the main concerns of physical planning is the proper designation of suitable sites for feasible and sustainable land use. A main importance of such issue is that it withdraws attention to the necessity of adopting a multidisciplinary approach to the zoning and site selection problem. Egypt has a top priority objective to develop Sinai Peninsula and to create new sustainable and attracting communities that should ensure a stable, economic and sustainable environment in vast desert zones. Due to the difficulty in solving a zoning problem in a desert, the use of remote sensing and Geographic Information System (GIS) was to explore the desert potentials in the region. Five sub-models were created for five themes using Spatial Multicriteria Analysis (SMCA) and used as inputs to the final suitability model. These themes are: land resources, land stability, accessibility, cost of construction and land protection. A GIS-based model was designed following a sustainable development approach. Economic, social and environmental factors were introduced in the model to identify and map land suitable zones for urban development using Analytical Hierarchy Process (AHP). The suitability index map for urban development was produced by weighted overlay of the five sub-models themes. The most suitable zones for urban development in Sinai Peninsula amounted to 5327 square kilometers representing 17% of total area, whereas high suitable zones reached 40% indicating a high suitability of Sinai Peninsula lands for residing new urban communities.

关键词： Urban Development Remote Sensing GIS Site Selection Themes Analytical Hierarchy Process Sinai Egypt

Latissimus Dorsi Mini-Flap as a Volume Replacement Technique after Partial Mastectomy for Breast Cancer in the Upper and Central Breast Quadrants: A Single Center Experience

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Surgical Science 2016年第11期7卷 496-504页

作者： Waleed Elnahas Ashraf Khater mohamed Hamdy Emadeldeen Hamed Osama Eldamshety mohamed hegazy Department of Surgical Oncology Oncology Center Faculty of Medicine Mansoura University Mansoura Egypt

Background: The latissimus dorsi (LD) muscle flap plays an essential role in breast reconstruction after partial mastectomy for cancer because of its stability and versatility. We evaluated both oncologic and aesthetic outcomes in addition to the related complications of this flap as an adjunct to breast conserving surgery in the management of breast cancer patients. Methods: All patients underwent a one-stage procedure with immediate reconstruction through two-steps operation;wider local excision utilizing oncoplastic principles and mini flap harvest & volume replacement. Results: The study included 34 cases with early breast cancer;30 patients had partial breast resection and defect refilling by LD mini-flap, three patients underwent mastectomy and one patient underwent extended LDF. The mean defect volume was (212.63 cm3 ± 59.57) cm3, while the mean flap volume was (218.27 cm3 ± 53.64 cm3). Patient self-evaluation of the cosmetic outcome was excellent in 20%, good in 60% and satisfactory in 20% of patients. Panel evaluation according to Harvard scale showed excellent in 36.7%, good in 36.7%, fair in 26.7% of patients. The median hospital stay was 4 days. The postoperative complications included wound gap in 4 patients (13.3%), postoperative donor site seroma in 16 patients (53.3%). No flap loss or necrosis, no affection on arm or shoulder mobility occurred. Lastly, no tumor recurrence till now. Conclusion: Latissimus dorsi mini-flap can achieve adequate cosmetic and oncologic outcomes with a low incidence of complications in patients with early stage (I/II) breast cancer and small to medium sized breasts.

关键词： Oncoplastic Breast Surgery Latissimus Dorsi Mini-Flap Conservative Surgery

Totally Endoscopic (Thoracoscopic and Laparoscopic) Radical Esophagectomy with Gastric Tube Reconstruction through a Small Neck Incision: An Early Experience with Thirty Egyptian Patients

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Surgical Science 2014年第5期5卷 214-223页

作者： Adel Denewer Adel Fathi Ahmed Setit mohamed hegazy Ashraf Khater Osama Hussein Sameh Roshdy Fayez Shahatto Fathy Denewer Department of Surgical Oncology Oncology Center (OCMU) Faculty of Medicine Mansoura University Mansoura Egypt

Background: Minimally invasive esophagectomy nowadays is replacing the classic open technique. Additional studies are needed to confirm its safety and efficacy. Methods: thirty patients with esophageal carcinoma were enrolled in this study. Patients were evaluated preoperatively and they underwent thoracoscopic and laparoscopic procedures for assessment of resectability. Resectablepatients underwent radical esophagectomy with gastric tube reconstruction through a four-cm neck incision. Results: 17 patients were operable and 13 patients were inoperable. The mean operative time for the whole procedure was 5.97 ± 1.66 hours. The mean blood loss was 250 ± 138.07 cc. The mean overall hospital stay was 17.47 ± 5.49 daysdays. Common postoperative complications included pneumonia (13.3%) pleural effusion (6.7%), cervical anastomotic leakage (10%), and wound infection (13.3%). One patient died in the early postoperative period. Conclusions: we conclude that totallyendoscopic (thoracoscopic and laparoscopic) esophagectomy is feasible and relatively safe technique. Beside its efficacy as an assessment tool, total esophagectomy and lymphadenectomy could be performed in the same time.

关键词： Thoracoscopic Laparoscopic Radical Esophagectomy Gastric Reconstruction Esophagus Cancer

Prevalence of Cerebral Atherosclerosis among Patients with Metabolic Syndrome: A Case Control Study on Egyptian Subjects

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World Journal of Cardiovascular Diseases 2016年第1期6卷 8-13页

作者： Sherif Elwan Tarek Zoheir Tawfik Heba Sayed Assal Shaimaa El-Jaafary Montasser mohamed hegazy Salwa Tawfik Alshaimaa Mahmoud Aboulfotooh Foad Abd-Allah Department of Internal Medicine National Research Institute Cairo Egypt Department of Neurology Cairo University Cairo Egypt

Background: The metabolic syndrome (MetS) is a clustering of vascular risk factors that tend to increase the risk of occurrence of diabetes mellitus type 2 (DMT2), cardiovascular and cerebro-vascular ischemic events. The aim of the present study is to investigate the association of extra-cranial and intracranial arterial atherosclerosis as well as silent brain infarction (SBI) with MetS, thereby determining the potential cerebrovascular atherosclerotic risk of MetS in the Egyptian population. Methods: A case control study was conducted on 50 Egyptian subjects with MetS and 30 without with age range from 40 - 60 years old. All participants were free from cerebrovascular ischemic events [stroke or transient ischemic attack (TIA)]. All participants underwent complete neurological examination, assessment of the diagnostic criteria for MetS, carotid and transcranial duplex ultrasonography (U/S) and brain MRI. Results: Preclinical carotid atherosclerosis (athero-sclerotic plaques with <50% stenosis) was associated with MetS (P value = 0.02) that persisted after adjustment for age and other confounders. There was no significant association between increased intima media thickness (IMT) and MetS. There was non-significant association between MetS and intracranial atherosclerotic disease (ICAD) or the degree of intracranial stenosis (ICS). Conversely, there was a highly significant association between MetS and SBI even after adjustment for age and other confounders (P value = 0.001). Conclusion: Metabolic syndrome is an important factor associated with mild to moderate atherosclerosis (<50% stenosis) and silent brain infarcts among asymptomatic individuals. Interventions to reduce MetS are important for prevention of subclinical and clinical cerebral atherosclerotic disease.

关键词： Metabolic Syndrome Preclinical Atherosclerosis Silent Brain Infarction Neurovascular Ultrasound Brain MRI Egyptian Population

The Effectiveness of Intraoperative Frozen Section Analysis of Safety Margins in Breast Conserving Surgery and the Role of Surgeon in Decreasing the Rate of Positive Margins

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Surgical Science 2017年第12期8卷 499-509页

作者： Omar Farouk Ahmed Senbel Mosab Shetiwy Essam Attia Ahmed Abdallah Osama El-Damshety Ashraf Khater Sameh Roshdy Amr Abouzid Amr Hossam Islam H. Metwally Omar Hamdy Amir M. Zaid Mahmoud Abdelaziz mohamed Elmetwally Adel Fathi Emad-Eldeen Hamed Khaled Abdel Wahab Wagdi El-Kashef mohamed Hafez Khaled Zalata mohamed hegazy Adel Denewer Surgical Oncology Department Oncology Center Faculty of Medicine Mansoura University Mansoura Egypt Pathology Department Faculty of Medicine Mansoura University Mansoura Egypt

Introduction: Nowadays the more accepted surgical option for treating early breast cancer is breast conserving surgery. The main challenge in this type of surgery is to get free safety margins without need of second surgical operation, so many breast surgeons have started to depend on intraoperative frozen sections to ensure free safety margins. Aim of work: To assess our policy that we prefer to depend on intraoperative frozen section analysis to get free safety margin in breast conserving surgery from the 1st surgery, and its oncologic outcome. Patients and Methods: This is a retrospective study conducted in Oncology Center—Mansoura University (OCMU), where the data of 219 patients with breast cancer, who were managed by breast conserving surgery with intraoperative frozen section analysis of the safety margins, was analyzed. Results: The intraoperative frozen section analysis of safety margin was negative from the start in 183 (83.6%) patients, while it was positive in 36 patients (16.4%). Intraoperative decision of margin re-excision was applied for 29 patients (13.2%) in order to reach negative margin, modified radical mastectomy was offered for 4 patients (1.8%), while nipple sparing mastectomy with immediate breast reconstruction using latissimus dorsi flap was offered for 3 patients (1.4%). The postoperative paraffin results were typical with intraoperative frozen section analysis results in 216 patients (98.6%) and different results were obtained in only 3 patients (1.4%) who were managed by modified radical mastectomy in a second operation. Only 4 patients had local recurrence (1.8%) during the period of follow-up duration which was ranged from 1 to 86 months with mean ± SD (22.3 ± 14.1). Conclusion: The intraoperative frozen section analysis of safety margins in breast conserving surgery has very high-rate typical results with the paraffin section analysis and it is very helpful in decreasing the rate of second surgical operation in cases of infiltrated m

关键词： Breast Conserving Surgery Intraoperative Frozen Section Analysis Safety Margins Breast

Effect of probiotics on pro-inflammatory cytokines and NF-κB activation in ulcerative colitis

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World Journal of Gastroenterology 2010年第33期16卷 4145-4151页

作者： Sahar K hegazy mohamed M El-Bedewy Department of Clinical Pharmacy Faculty of PharmacyTanta University Internal Medicine Faculty of MedicineTanta University

AIM:To demonstrate the therapeutic effect of probiotics in patients with ulcerative colitis(UC),and their effect on inflammatory mediators and nuclear factor(NF)κB activation in these ***:Thirty patients with mild to moderate UC were randomly classified into two groups:sulfasalazine group,who received sulfasalazine 2400 mg/d;and probiotic group,who received sulfasalazine 2400 mg/d with *** patients were investigated before and after 8 wk of treatment with probiotic(Lactobacillus delbruekii and Lactobacillus fermentum).Colonic activity of myeloperoxidase(MPO)was assayed with UV spectrophotometry,the colonic content of interleukin(IL)-6 was determined by enzyme-linked immunosorbent assay(ELISA),fecal calprotectin was determined by ELISA,and expression of NF-κB p65 and tumor necrosis factor (TNF)-αproteins in colonic tissue was identified by immunohistochemistry and reverse transcription polymerase chain reaction,***:At the start of the study,colonic mucosal injury and inflammation were demonstrated in UC patients by hematoxylin and eosin staining,and an increase in colonic MPO activity,fecal calprotectin,and expression of colonic TNF-αand NF-κB p65 *** use of probiotic for 8 wk significantly ameliorated the inflammation by decreasing the colonic concentration of IL-6,expression of TNF-αand NF-κB p65,leukocyte recruitment,as demonstrated by a decrease in colonic MPO activity,and the level of fecal calprotectin compared to sulfasalazine group and the control group(P<0.05).CONCLUSION:Oral supplementation with probiotics could be helpful in maintaining remission and preventing relapse of UC.

关键词： Ulcerative colitis Probiotics Interleukin-6 Nuclear factor-κB

Antifibrotic effect of aloe vera in viral infection-induced hepatic periportal fibrosis

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World Journal of Gastroenterology 2012年第17期18卷 2026-2034页

作者： Sahar K hegazy mohamed El-Bedewy Akira Yagi Department of Clinical Pharmacy Faculty of PharmacyTanta UniversityTanta 8130Egypt Department of Internal Medicine Faculty of MedicineTanta UniversityTanta 8130Egypt Placenta/Aloe Research Institute Japan Bio-Products Co.Ltd.1488-4Aikawa-machiKurume-shiFukuoka Bio Factory 204Fukuoka 839-0861Japan

AIM:To investigate the anti-oxidative and anti-fibrotic effects of aloe vera in patients with liver ***:Aloe vera high molecular weight fractions(AHM) were processed by patented hyper-dry system in combination of freeze-dry technique with microwave and far infrared-ray *** healthy volunteers as the control group and 40 patients were *** patients were randomly subdivided into two equal groups:the conventional group was treated with placebo(starch),and AHM group was treated with 0.15 gm/d AHM,both for 12 consecutive *** patients were investigated before and after *** activity of aspartate aminotransferase(AST),alanine aminotransferase(ALT),alkaline phosphatase(ALP),hyaluronic acid(HA),transforming growth factor-β(TGF-β) and matrixmetalloproteinase-2(MMP-2) were *** reduced glutathione(GSH) and malondialdehyde(MDA) levels in liver were assayed and the expression of hepatic α-smooth muscle actin(α-SMA) was identified by ***:At the start of the study,the hematoxylin and eosin staining revealed fibro-proliferated bile ductules,thick fibrous septa and dense inflammatory cellular infiltration in the patients before *** use of AHM for 12 wk significantly ameliorated the fibrosis,inhibited the inflammation,and resulted in minimal infiltration and minimal fibrosis compared to the conventional *** enzyme activities of the liver(ALT,AST and ALP) were attenuated after treatment in both groups,and the decrease in the AHM group was more significant as compared with the conventional *** to the AST,the MDA levels were significantly higher before treatment,and were attenuated after treatment in both *** contrast,the hepatic glutathione content in the patients were decreased significantly in the AHM group compared to the *** serum levels of the fibrosis markers(HA,TGF-β and MMP-2) were also reduced significantly after *** expression of α-SMA was m

关键词： Hepatic fine periportal fibrosis Aloe vera α-smooth muscle actin Transforming growth factor-β Hyaluronic acid

Load Frequency Control of Multi-interconnected Renewable Energy Plants Using Multi-Verse Optimizer

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Computer Systems Science & Engineering 2021年第5期37卷 219-231页

作者： hegazy Rezk mohamed A.mohamed Ahmed A.Zaki Diab N.Kanagaraj College of Engineering at Wadi Addawaser Prince Sattam Bin Abdulaziz UniversityWadi Addawaser11991Saudi Arabia Electrical Engineering Department Faculty of EngineeringMinia UniversityMinia61111Egypt

A reliable approach based on a multi-verse optimization algorithm(MVO)for designing load frequency control incorporated in multi-interconnected power system comprising wind power and photovoltaic(PV)plants is presented in this *** has been applied for optimizing the control parameters of the load frequency controller(LFC)of the multi-source power system(MSPS).The MSPS includes thermal,gas,and hydro power plants for energy ***,the MSPS is integrated with renewable energy sources(RES).The MVO algorithm is applied to acquire the ideal parameters of the controller for controlling a single area and a multi-area MSPS integrated with *** link is utilized in shunt with AC multi-areas interconnection tie *** proposed scheme has achieved robust performance against the disturbance in loading conditions,variation of system parameters,and size of step load perturbation(SLP).Meanwhile,the simulation outcomes showed a good dynamic performance of the proposed controller.

关键词： Load frequency control multi-verse optimization multi-area power system renewable energy sources

Modeling and Optimization of Surface Roughness of Epoxy/Nanoparticles Composite Coating

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Computers, Materials & Continua 2022年第4期71卷 71-83页

作者： A.F.mohamed J.Abu Alsoud Mujahed Al-Dhaifallah hegazy Rezk mohamed K.Hassan Department of Mechanical Engineering College of Engineering&Islamic Arch.Umm Alqura UniversityMakkahSaudi Arabia Department of Mechanical Engineering Faculty of EngineeringSohag UniversitySohagEgypt Department of Systems Engineering King Fahd University of Petroleum&MineralsDhahran31261KSA College of Engineering at Wadi Addawaser Prince Sattam Bin Abdulaziz UniversityAl-Kharj11911Saudi Arabia Department of Electrical Engineering Faculty of EngineeringMinia UniversityMinia61517Egypt Department of Production Engineering and Design Faculty of EngineeringMinia UniversityMinia61517Egypt

In power plants,flue gases can cause severe corrosion damage in metallic parts such as flue ducts,heat exchangers,and *** is an effective technique to prevent this damage.A robust fuzzy model of the surface roughness(Ra and Rz)of flue gas ducts coated by protective composite coating from epoxy and nanoparticles was constructed based on the experimental *** proposed model consists of four nanoparticles(ZnO,ZrO2,SiO2,and NiO)with 2%,4%,6%,and 8%,*** surface methodology(RSM)was used to optimize the process parameters and identify the optimal conditions for minimum surface roughness of this coated *** prove the superiority of the proposed fuzzy model,the model results were compared with those obtained by ANOVA,with the coefficient of determination and the root-mean-square error(RMSE)used as *** Ra,for the first output response,using ANOVA,the coefficient-of-determination values were 0.9137 and 0.4037,respectively,for training and ***,for Rz,the second output response,the coefficient-of-determination results were 0.9695 and 0.4037,respectively,for training and *** the fuzzy modeling of Ra,for the first output response,the RMSE values were 0.0 and 0.1455,respectively,for training and *** values for the coefficient of determination were 1.00 and 0.9807,respectively,for training and *** results prove the superiority of fuzzy *** modeling the second output response Rz,the RMSE values were 0.0 and 0.0421,respectively,for training and testing,and the coefficient-of-determination values were 1.00 and 0.9959,respectively,for training and testing.

关键词： Materials coating nanoparticles modeling and optimization