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Open Journal of Modern Neurosurgery 2020年第3期10卷 318-324页

作者： Hieder Al-Shami Ahmed M. Salah mohamed fathy adel ali Al-Ahly Bank Hospital Cairo Egypt Department of Neurosurgery Faculty of Medicine Kasr-Alainy Medical School Cairo Egypt

Background: Fixation of bone flap following craniotomy is usually achieved by synthetic materials. In rural and poor funding areas, innovation for cheap, safe and applicable material is needed. Purpose: The aim is to assess our new innovative technique in bone flap fixation against traditional techniques. Patients and Methods: The study was a prospective randomized controlled study enrolled at Al-Amal Hospital and Al-Ahly Bank Hospital from 2014-2019. Forty-eight patients were randomized in the study. Group A (24 patients) underwent titanium miniplate fixation while group B (24 patients) underwent our new technique. The new technique is double J tunnels performed by craniotome on either side of the bone (flap and skull sides), then a Prolene suture is passed through the shared stem of J’ holes and secured in the wrapped side of J’s holes and tying it tightly. Both techniques were examined against fixation time, rigidity, offset and final judgment postoperatively. Result: There was no statistically significant difference in using both techniques as regard fixation time. Our new technique was not inferior to the traditional one in achieving rigidity (p > 0.05). The final postoperative assessment was as equal as that seen in miniplate fixation. Conclusion: This technique is a simple, easy, cheap and effective method of fixing craniotomy bone flap.

关键词： Craniotomy Bone Flap Fixation Miniplate Fixation

Small heat shock protein B8:from cell functions to its involvement in diseases and potential therapeutic applications

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Neural Regeneration Research 2025年第10期20卷 2872-2886页

作者： Marta Chierichetti Riccardo Cristofani Valeria Crippa Veronica Ferrari Marta Cozzi Elena Casarotto Paola Pramaggiore Laura Cornaggia Guglielmo Patelli ali mohamed Margherita Piccolella Mariarita Galbiati Paola Rusmini Barbara Tedesco Angelo Poletti Laboratory of Experimental Biology Dipartimento di Scienze Farmacologiche e Biomolecolari“Rodolfo Paoletti”(DiSFeB)Universitàdegli Studi di MilanoMilanItaly

Heat shock protein family B(small)member 8(HSPB8)is a 22 kDa ubiquitously expressed protein belonging to the family of small heat shock ***8 is involved in various cellular mechanisms mainly related to proteotoxic stress response and in other processes such as inflammation,cell division,and ***8 binds misfolded clients to prevent their aggregation by assisting protein refolding or degradation through chaperone-assisted selective *** line with this function,the pro-degradative activity of HSPB8 has been found protective in several neurodegenerative and neuromuscular diseases characterized by protein misfolding and *** cancer,HSPB8 has a dual role being capable of exerting either a pro-or an anti-tumoral activity depending on the pathways and factors expressed by the model of cancer under ***,HSPB8 exerts a protective function in different diseases by modulating the inflammatory response,which characterizes not only neurodegenerative diseases,but also other chronic or acute conditions affecting the nervous system,such as multiple sclerosis and intracerebellar *** note,HSPB8 modulation may represent a therapeutic approach in other neurological conditions that develop as a secondary consequence of other *** is the case of cognitive impairment related to diabetes mellitus,in which HSPB8 exerts a protective activity by assuring mitochondrial *** review aims to summarize the diverse and multiple functions of HSPB8 in different pathological conditions,focusing on the beneficial effects of its ***-based and alternative therapeutic approaches targeting HSPB8 and its regulated pathways will be discussed,emphasizing how new strategies for cell and tissue-specific delivery represent an avenue to advance in disease treatments.

关键词： aggregation autophagy cancer chaperone chaperone-assisted selective autophagy cognitive impairment HSPB8 neuroinflammation neuromuscular diseases therapy

SIMPLE PROOFS OF THE CAUCHY-SCHWARTZ INEQUaliTY AND THE NEGATIVE DISCRIMINANT PROPERTY IN ARCHIMEDEAN ALMOST f-ALGEBRAS

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Analysis in Theory and Applications 2009年第2期25卷 117-124页

作者： adel Toumi mohamed ali Toumi Nedra Toumi Laboratoire de Physique des Liquides Critiques Département de Physique Faculté des Sciences de Bizerte 7021 Zarzouna Bizerte Tunisia Département des Mathématiques Faculté des Sciences de Bizerte 7021 Zarzouna Bizerte Tunisia

The paper presents simple proofs of the Cauchy-Schwartz inequality and the negative discriminant property in archimedean almost f-algebras^[5], based on a sequence approximation.

关键词： Cauchy-Schwartz inequality f-algebra almost f-algebra positive square g-algebra

3D static modeling and sequence stratigraphy using well logs and seismic data:An example of Abu Roash G member in Bahga oilfield

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Energy Geoscience

Energy Geoscience 2024年第3期5卷 362-377页

作者： mohamed Reda mohamed fathy mohamed Mosaad Fahad Alshehri mohamed S.Ahmed Geology Department Faculty of ScienceAl-Azhar UniversityP.O.Box 11884Nasr CityCairoEgypt Abdullah Alrushaid Chair for Earth Science Remote Sensing Research Geology and Geophysics DepartmentCollege of ScienceKing Saud UniversityRiyadh11451Saudi Arabia

This research uses both three-dimensional(3D)modeling and geologic well control to piece back together the architectural parts of the Late Cretaceous *** goal is to figure out the sizes,directions,locations,and controls of the layers of the fluvial sandstone *** stratigraphy is essential for 3D reservoir modeling and petroleum geology understanding in the Bahga *** purpose of this work is to create a static model that shows the layers and facies distribution in the reservoir *** will use data from nine well logs and 22 seismic lines calibrated by the Abu Roash G Member reservoir core intervals to accomplish *** petrophysical study discovered three parts in the Abu Roash G Member reservoir rock:channel fill that is affected by tides,channel fill that is dominated by tides(intertidal sands),and channel top with lenticular bedded *** model's findings point to the existence of an NNW-oriented sand body,which could be a prime location to produce *** original oil in place(OOIP)is about 3,438,279 Stock Tank Barrels(STB),and the oil reserve reaches up to 1,031,484(STB).Sequence stratigraphic analysis using seismic and well log information(SB)reveals that the Upper Cretaceous AR/G reservoir of the Bahga field is characterized by third-and fourth-order stratigraphic sequences,which are constrained by three Maximum Flooding Surfaces(MFS)and two Sequence *** integration of the derived geological model and sequence stratigraphic results can lower future extraction risk by identifying the locations and trends of the geologic facies with the necessary petrophysical properties for the hydrocarbon accumulations.

关键词： Three-dimensional reservoir modeling Sequence stratigraphy Reservoir characterization Abu Roash reservoir Abu Gharadig Basin

A Stochastic Flight Problem Simulation to Minimize Cost of Refuelling

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Computers, Materials & Continua 2021年第10期69卷 849-871页

作者： Said ali Hassan Khalid Alnowibet Miral H.Khodeir Prachi Agrawal adel F.Alrasheedi ali Wagdy mohamed Department of Operations Research and Decision Support Faculty of Computers and Artificial IntelligenceCairo UniversityGiza12613Egypt Department of Statistics and Operations Research College of ScienceKing Saud UniversityRiyadh11451Kingdom of Saudi Arabia Department of Mathematics and Scientific Computing National Institute of Technology HamirpurHimachal Pradesh177005India Department of Operations Research Faculty of Graduate Studies for Statistical ResearchCairo UniversityGiza12613Egypt Wireless Intelligent Networks Center(WINC) School of Engineering and Applied SciencesNile UniversityGizaEgypt

Commercial airline companies are continuously seeking to implement strategies for minimizing costs of fuel for their flight routes as acquiring jet fuel represents a significant part of operating and managing expenses for airline activities.A nonlinear mixed binary mathematical programming model for the airline fuel task is presented to minimize the total cost of refueling in an entire flight route *** model is enhanced to include possible discounts in fuel prices,which are performed by adding dummy variables and some restrictive constraints,or by fitting a suitable distribution function that relates prices to purchased *** obtained fuel plan explains exactly the amounts of fuel in gallons to be purchased from each airport considering tankering strategy while minimizing the pertinent cost of the whole flight *** relation between the amount of extra burnt fuel taken through tinkering strategy and the total flight time is also considered.A case study is introduced for a certain flight rotation in domestic US air transport *** mathematical model including stepped discounted fuel prices is *** problem has a stochastic nature as the total flight time is a random variable,the stochastic nature of the problem is realistic and more appropriate than the deterministic *** stochastic style of the problem is simulated by introducing a suitable probability distribution for the flight time duration and generating enough number of runs to mimic the probabilistic real *** similar real application problems are modelled as nonlinear mixed binary ones that are difficult to handle by exact ***,metaheuristic approaches are widely used in treating such different optimization *** this paper,a gaining sharing knowledge-based procedure is used to handle the mathematical *** algorithm basically based on the process of gaining and sharing knowledge throughout the human *** generated simulation runs of

关键词： Stochastic flight problem cost of refuelling ferrying strategy tankering discounted prices simulation procedure nonlinear mixed binary model metaheuristic algorithm gaining-sharing knowledge-based algorithm

An Artificial Intelligence Approach for Solving Stochastic Transportation Problems

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Computers, Materials & Continua 2022年第1期70卷 817-829页

作者： Prachi Agrawal Khalid Alnowibet Talari Ganesh adel F.Alrasheedi Hijaz Ahmad ali Wagdy mohamed Department of Mathematics and Scientific Computing National Institute of Technology HamirpurHimachal Pradesh177005India Statistics and Operations Research Department College of ScienceKing Saud UniversityRiyadh11451Kingdom of Saudi Arabia Section of Mathematics International Telematic University UninettunoRoma00186Italy Operations Research Department Faculty of Graduate Studies for Statistical ResearchCairo UniversityGiza12613Egypt Wireless Intelligent Networks Center(WINC) School of Engineering and Applied SciencesNile UniversityGizaEgypt

Recent years witness a great deal of interest in artificial intelligence(AI)tools in the area of *** has developed a large number of tools to solve themost difficult search-and-optimization problems in computer science and operations ***,metaheuristic-based algorithms are a sub-field of *** study presents the use of themetaheuristic algorithm,that is,water cycle algorithm(WCA),in the transportation problem.A stochastic transportation problem is considered in which the parameters supply and demand are considered as random variables that follow the Weibull *** the parameters are stochastic,the corresponding constraints are *** are converted into deterministic constraints using the stochastic programming *** this study,we propose evolutionary algorithms to handle the difficulties of the complex high-dimensional optimization *** is influenced by the water cycle process of how streams and rivers flow toward the sea(optimal solution).WCA is applied to the stochastic transportation problem,and obtained results are compared with that of the new metaheuristic optimization algorithm,namely the neural network algorithm which is inspired by the biological nervous *** is concluded that WCA presents better results when compared with the neural network algorithm.

关键词： Artificial intelligence metaheuristic algorithm stochastic programming transportation problem water cycle algorithm weibull distribution

Numerical Analysis of Laterally Loaded Long Piles in Cohesionless Soil

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Computers, Materials & Continua 2022年第5期71卷 2175-2190页

作者： Ayman Abd-Elhamed mohamed fathy Khaled M.Abdelgaber Physics and Engineering Mathematics Department Faculty of Engineering-MattariaHelwan UniversityCairo11718Egypt Faculty of Engineering King Salman International UniversitySouth SinaiRas SedrEgypt Basic and Applied Science Department College of Engineering and TechnologyArab Academy for ScienceTechnology and Maritime TransportCairo11799Egypt

The capability of piles to withstand horizontal loads is a major design *** current research work aims to investigate numerically the responses of laterally loaded piles at working load employing the concept of a beam-on-Winkler-foundation *** governing differential equation for a laterally loaded pile on elastic subgrade is *** on LegendreGalerkin method and Runge-Kutta formulas of order four and five,the flexural equation of long piles embedded in homogeneous sandy soils with modulus of subgrade reaction linearly variable with depth is solved for both free-and fixed-headed ***,as one of the world’s leading computational software,was employed for the implementation of *** proposed numerical techniques provide the responses for the entire pile length under the applied lateral *** utilized numerical approaches are validated against experimental and analytical results of previously published works showing a more accurate estimation of the response of laterally loaded ***,the proposed approaches can maintain both mathematical simplicity and comparable accuracy with the experimental results.

关键词： Numerical solution laterally loaded pile cohesionless soil Legendre-Galerkin Runge-Kutta

Energy Management Control StraEnergy Management Control Strategy for Renewable Energy System Based on Spotted Hyena Optimizertegy for Renewable Energy System Based on Spotted Hyena Optimizer

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Computers, Materials & Continua 2021年第5期67卷 2271-2281页

作者： Hegazy Rezk Ahmed fathy Mokhtar Aly mohamed N.Ibrahim College of Engineering at Wadi Addawaser Prince Sattam Bin Abdulaziz UniversityWadi Addawaser11991Saudi Arabia Electrical Engineering Department Faculty of EngineeringMinia UniversityMinia61111Egypt Electrical Engineering Department Faculty of EngineeringJouf UniversitySakakaSaudi Arabia Electrical Power and Machine Department Faculty of EngineeringZagazig UniversityZagazigEgypt Department of Electrical Engineering Aswan UniversityAswan81542Egypt Electronics Engineering Department Universidad Tecnica Federico Santa MariaValparaiso2390123Chile Department of Electromechanical Systems and Metal EngineeringGhent UniversityGhent9000Belgium FlandersMake@UGent–corelab EEDT-MP 3001LeuvenBelgium Electrical Engineering Department Kafrelshiekh UniversityKafr el-Sheikh33511Egypt

Hydrocarbons,carbon monoxide and other pollutants from the transportation sector harm human health in many *** cell(FC)has been evolving rapidly over the past two decades due to its efficient mechanism to transform the chemical energy in hydrogen-rich compounds into electrical *** main drawback of the standalone FC is its slow dynamic response and its inability to supply rapid variations in the load ***,adding energy storage systems is ***,to manage and distribute the power-sharing among the hybrid proton exchange membrane(PEM)fuel cell(FC),battery storage(BS),and supercapacitor(SC),an energy management strategy(EMS)is *** this research work,an optimal EMS based on a spotted hyena optimizer(SHO)for hybrid PEM fuel cell/BS/SC is *** main goal of an EMS is to improve the performance of hybrid FC/BS/SC and to reduce the amount of hydrogen *** prove the superiority of the SHO method,the obtained results are compared with the chimp optimizer(CO),the artificial ecosystem-based optimizer(AEO),the seagull optimization algorithm(SOA),the sooty tern optimization algorithm(STOA),and the coyote optimization algorithm(COA).Two main metrics are used as a benchmark for the comparison:the minimum consumed hydrogen and the efficiency of the *** main findings confirm that the minimum amount of hydrogen consumption and maximum efficiency are achieved by the proposed SHO based EMS.

关键词： Modelling optimization energy management fuel cell supercapacitor hybrid system

Introduction of longstanding complicated sulcus intraocular lens into the intact capsular bag

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International Journal of Ophthalmology(English edition) 2021年第11期14卷 1779-1783页

作者： fathy Fawzy Morkos Nader fathy Fawzy mohamed El Bahrawy Rania Serag Elkitkat Watany Research and Development Center Watany Eye HospitalCairo 11799Egypt Department of Ophthalmology Faculty of MedicineAin Shams UniversityCairo 11799Egypt

AIM:To propose a surgical technique that successfully reopened the empty and intact capsular bag after long periods of closure,with repositioning of the intraocular lens(IOL)from the ciliary sulcus into its preferred habitat inside the capsular ***:This is a case series,prospective,and interventional *** technique was first performed on an aphakic high myope with a closed posterior capsule for 18 ***,five patients with recurrently displaced sulcus IOLs for a range of 1 mo to 7 y were performed for the same *** surgery,identifying a"telltale white line"was an important landmark for detecting the site of major adhesions between the edge of the capsulorhexis and the posterior *** adhesions were freed using combined manual and viscoelastic dissection,followed by an easier freeing of adhesions along the whole capsular *** IOL was safely implanted,exchanged,or introduced from the sulcus into the fibrotic and closed capsular *** were followed up for a period ranging from 6 to 17 mo ***:All the patients experienced a remarkable improvement in their subjective *** lamp examination showed a postoperative centralized IOL in the *** follow up visits confirmed visual and IOL ***:This newly-introduced surgical technique facilitates the reopening of the empty yet intact capsular bag that has been closed by fibrotic proliferations,with secured implantation of the IOL inside the capsular *** with inadvertent implantation of IOLs into the ciliary sulcus,yet having an intact capsular bag,can benefit from this technique.

关键词： late in the bag technique displaced sulcus lOLs post cataract visual rehabilitation closed capsular lens bag

Anti-wear properties evaluation of frictional sliding interfaces in automobile engines lubricated by copper/graphene nanolubricants

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Friction 2020年第5期8卷 905-916页

作者： mohamed Kamal Ahmed ali Xianjun HOU mohamed AAABDELKAREEM Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan 430070China Automotive and Tractors Engineering Department Faculty of EngineeringMinia UniversityEl-Minia 61111Egypt Hubei Collaborative Innovation Center for Automotive Components Technology Wuhan 430070China

Owing to the significance of improving fuel economy, reducing emissions, and extending the durability of engine components, this study focused on the tribological performance of nano-additives. In this study, copper (Cu) and graphene (Gr) nanomaterials were dispersed in a fully formulated engine oil (5W-30) with different concentrations. The tribological trials were investigated under various speeds and loads, utilizing a reciprocating tribometer to mimic the ring/liner interfaces in the engine. The frictional surface morphologies were com-prehensively analyzed using electron probe X-ray microanalysis (EPMA), field emission scanning electron microscopy (FESEM), energy dispersive spectrometer (EDS), and three dimensional (3D) surface profilometry to explore the mechanisms responsible for improving the tribological performance of the frictional sliding parts in the engine. The tribological test results illustrated that lubrication by nano-additives reduced the wear rate (WR) and friction coefficient (COF) by 25%–30% and 26.5%–32.6%, respectively, as compared with 5W-30. The results showed that this is a promising approach for increasing the durability and lifespan of frictional sliding components and fuel economy in automobile engines.

关键词： engine tribology nanomaterial nanolubricant friction wear tribofilm