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Value of Platelet to Lymphocytes Ratio in Predicting Angiographic Reflow after Primary Percutaneous Coronary Intervention in STEMI Patient

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World Journal of Cardiovascular Diseases 2019年第4期9卷 300-308页

作者： Ahmed Emara Neveen I. Samy Walaa Farid mohamed elgendy Department of Cardiology Faculty of Medicine Menoufia University Al Minufya Egypt

Background: Acute myocardial infarction is a leading cause of death worldwide nowadays and treatment of choice is primary percutaneous coronary intervention (PCI). No reflow is a complication that increases mortality and morbidity post intervention and one of its predictors is platelet lymphocyte ratio. Aim of Study: To assess relation between admission platelet to lymphocyte ratio (PLR) and angiographic reflow after primary PCI in acute ST elevation myocardial infarction (STEMI). Patients and Methods: This is a prospective study that was conducted from May 2017 to May 2018 at Cardiology Department, Menoufia University Hospital. Sixty patients presented with ST-elevation myocardial infarction who were eligible for primary PCI were enrolled in the study. According to TIMI flow post intervention, patients were arranged into 2 groups: Group 1 (Normal Reflow) included thirty patients with post intervention TIMI flow III and Group 2 (NO Reflow) included thirty patients with post intervention TIMI flow (0, I, II). Comparison between both groups was done regarding platelet lymphocyte ratio (PLR). Result: PLR was significantly higher in patients with coronary no reflow than in patients with normal reflow with a P-value of , timing interval between onset of chest pain to time of intervention and thrombus grading was significantly higher in patients with no reflow than in patients with normal reflow. Conclusion: Pre-intervention PLR is an independent predictor of slow flow/no reflow following PPCI in patient with acute STEMI.

关键词： Acute Myocardial Infarction Primary Percutaneous Coronary Intervention No Reflow Platelet Lymphocyte Ratio

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Combination of Diclofenac Potassium and Propolis in the Therapy of Oral Aphthosis: A Randomized, Clinical, Double-Blind, Placebo-Controlled Study

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Open Journal of Stomatology 2023年第11期13卷 422-432页

作者： mohamed Ismail Assadawy Hisham mohamed Abozaid Abdelraheem Ramadan elgendy Abdelrahman mohamed Galal Department of Oral Medicine Periodontology Oral Diagnosis and Oral Radiology Faculty of Dental Medicine (Boys-Cairo) Al-Azhar University Cairo Egypt Department of Oral Biology Faculty of Dental Medicine (Boys-Cairo) Al-Azhar University Cairo Egypt

Background: Oral aphthosis has a negative impact on oral health. This study aimed to assess the effectiveness of gel formulation including diclofenac and propolis in the treatment of oral ulcers. Methods: Participants included 100 normal individuals with aphthous, excluding those having allergies to any ingredient in the diclofenac formulation. Patients were randomly assigned into two groups: one group received treatment with a combination of diclofenac potassium 3% (10 mg/g, 60 g) and propolis 5% gel (Group II), and the other group received a placebo (Group 1). The patient was evaluated using standard digital photographs and chronic oral mucosal questionnaires on days 1, 3, 5, and 7 after healing. Utilizing the Mann-Whitney U test, the two groups were compared. Each group’s changes were examined using Friedman’s test. Results: There was a statistically dramatic change over time in Group II. After one day, the median total score dropped statistically significantly, and from one to three days with effect size (d) 2.485, Group II demonstrated 48% complete healing and 52% partial healing, while Group I demonstrated 4% partial healing and 96% no change. Effect size (V): 0.995. Conclusions: The combination of diclofenac and propolis provided instant relief and an affordable new regimen for treating oral aphthosis.

关键词： Ulcer Biology Healing Inflammation Corticosteroids Propolis Diclofenac Potassium Oral Aphthosis

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Plasmas Created in the Interaction of Antiprotons with Atomic and Ionized Hydrogen Isotopes. Suggested Fuels for Space Engines

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Journal of High Energy Physics, Gravitation and Cosmology 2022年第1期8卷 14-24页

作者： mohamed Assaad Abdel-Raouf Abdelfattah T. elgendy Amr Abd Al-Rahman Youssef Physics Department Faculty of Science Ain Shams University Cairo Egypt Mathematics Department Faculty of Science Al-Azhar University Cairo Egypt

The main objective of the present work is to investigate the properties of plasmas created by injecting a thermalized beam of antiprotons in two types of media. The first is hydrogen, deuterium, or tritium atoms localized in palladium crystals. The second medium is composed of protons, deuterons, or tritons localized in a magnetic cavity. Particularly, it is demonstrated that huge amounts of energy are released in both cases which could be used as fuels for space shuttle engines. A novel mathematical scheme is employed to calculate the energy yields in real space at different incident energies of the antiprotons.

关键词： Antiprotons Antiprotonic Hydrogens Antiprotonic Plasma Fuel for Space Engines Plasmas in Molecular Crystals Palladium as Host for Neutral Plasma Antiprotons-Ionized Hydrogen Isotopes Plasma

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Cold Fusion Based on Matter-Antimatter Plasma Formed in Molecular Crystals

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Journal of High Energy Physics, Gravitation and Cosmology 2022年第1期8卷 56-66页

The main purpose of this work is to shed light on the possibility of producing huge amount of energy based on the construction matter-antimatter plasma in a molecular crystal. It is assumed that two beams of isothermal hydrogen and antihydrogen are injected into a palladium crystal leading to a plasma state composed of particles and antiparticles. The collapse of this state releases a huge amount of energy which can be used as fuel for space shuttles. Thus, the novel system of isothermal pressure interaction enhances the energy power carried out by the quantum ion acoustic soliton (QIAS). In addition to the energy power released from the particle-antiparticle annihilation. The probability of merging the energy from these two cases is available at certain condition. The released energy may be a significant step in solving the energy scape of Tokomak to produce fusion energy. The study starting from the one-dimensional quantum hydrodynamic model (in which the term of electron-positron and proton-antiproton for hydrogen-antihydrogen is included), a Korteweg de Vries equation (kdv) is derived, the QIAS energy experiences and the annihilation energy power are calculated. It is found that the total energy of QIAS and the energy resulting from hydrogen-antihydrogen annihilation are important step towards the establishment of a cold fusion power station.

关键词： Cold Fusion Annihilation Energy Plasma Energy Ion-Acoustic Plasma Cold and Hot Plasma Matter-Antimatter Plasma in Molecular Crystals Fuel for Space Shuttles in Palladium Crystals

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COVID-19 Patients with Hepatic Complications During the Third Wave of Pandemic in Egypt

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Journal of Clinical and Nursing Research 2022年第3期6卷 108-121页

作者： Alzhraa M Fahmy Marwa O elgendy Ahmed M Khalaf Mona A Abdelrahman mohamed EA Abdelrahim Ahmed O El-Gendy Tropical Medicine and Infectious Diseases Department Faculty of MedicineBeni-Suef UniversityBeni-SuefEgypt Department of Clinical Pharmacy Teaching Hospital of Faculty of MedicineFaculty of MedicineBeni-Suef UniversityBeni-Sueft Egypt Department of Clinical Pharmacy Faculty of PharmacyNahda University(NUB)Egypt Internal Medicine Department Faculty of MedicineBeni-Suef University Beni-SuefEgypt Clinical Pharmacy Department Faculty of PharmacyBeni-Suef University Beni-SuefEgypt Department of Microbiology and Immunology Faculty of PharmacyBeni-Suef University Beni-SuefEgypt

COVID-19 is a respiratory infection that has lately begun to affect other vital organs,including the heart,kidney,and *** purpose of this study was to investigate the hepatic complications in COVID-19 patients and the risk of being admitted to ICU or facing ***:Comorbidities(hypertension and diabetes),COVID-19 symptoms,laboratory findings(ALT level,AST level,and albumin),complications during hospitalization,treatment protocol used,and survival outcomes were all studied in 200 COVID-19 infected Egyptian patients who had virological symptoms and were followed up until they recovered or *** was found that older people and those with higher blood glucose levels have a higher risk of developing liver-associated COVID-19 ***,the majority of patients who developed liver complications in the course of the infection had high mortality *** with diabetes,hypertension,or hepatic disease are at higher risk of ICU admission or ***,it is important to pay attention to these problems in the diagnosis and treatment of COVID-19 to develop a suitable individualized treatment *** was also a correlation between the mortality in COVID-19 patients and both,high blood glucose and liver enzyme *** can be attributed to the correlation between diabetes and liver disease as every disease may be a complication to the other;moreover,COVID-19 may lead to increased blood sugar levels in addition to ALT and AST *** theory is that COVID-19 may afiect the liver and hence people with chronic liver disease.

关键词： COVID-19 Hepatic complications Third wave

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Addition of Inhalation Training Devices and Smartphone Application to Verbal Counseling for Asthmatic Patients

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Journal of Clinical and Nursing Research 2022年第2期6卷 76-79页

作者： Rania AA Mahmoud Sara M Tony Marian S Boshra Mona A Abdelrahman Haitham Saeed Hasnaa Osama Marwa O elgendy mohamed EA Abdelrahim Clinical Pharmacy Department Faculty of PharmacyBeni-Suef UniversityBeni-SuefEgypt Beni-Suef Specialized Hospital Beni-SuefEgypt Technical Office of Deputy Minister of Health in Beni-Suif Directorate of Health Affairs Beni-SuefEgypt Department of Clinical Pharmacy Teaching Hospital of Faculty of MedicineFaculty of MedicineBeni-Suef UniversityBeni-SuefEgypt Department of Clinical Pharmacy Faculty of PharmacyNahda University(NUB)Egypt

Background:One of the main issues with pressurized metered dose inhalers(pMDI)is that some patients find it difficult to use it ***:This study was carried out to compare the effect of traditional verbal counseling and that of adding an inhalation training device,such as Flo-Tone or Clip-Tone,along with a smartphone application on the incidence of inhalation technique mistakes and the pulmonary function of asthmatic adults and ***:The lung function of those in the advanced counseling group significantly improved on the second visit(p<0.001),whereas for those in the verbal counseling group,their lung function only improved on the third visit(p<0.001).For both the groups,the mean number of mistakes in regard to the steps in inhalation technique decreased significantly(p<0.001),with an overall higher percentage in the advanced counseling ***:The use of training devices and smartphone applications in addition to traditional verbal counseling for teaching asthmatic adults and children the correct inhalation technique steps using pMDI resulted in a significant improvement in pulmonary function and a significant reduction in the number of inhalation technique mistakes,compared to traditional verbal counseling alone.

关键词： Flo-Tone Clip-Tone Counseling Asthma in adults and children Inhalation technique MDI,FEV1 PEF Smartphone application

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An Observational Study on the Management of COVID-19 Patients in Limited-Resource Hospitals

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Journal of Clinical and Nursing Research 2022年第3期6卷 43-53页

作者： Marwa O elgendy Ahmed M Khalaf Ahmed O El-Gendy Mona A Abdelrahman Sara O El Gendy Ahmed M Abdel Hamied Omar Essam Karim Al Amir Esraa M Yousry mohamed EA Abdelrahim Department of Clinical Pharmacy Teaching Hospital of Faculty of MedicineFaculty of MedicineBeni-Suef UniversityBeni-Suet Egypt Department of Clinical Pharmacy Faculty of PharmacyNahda University(NUB)Egypt Internal Medicine Department Faculty of MedicineBeni-Suef UniversityBeni-Suef Egypt Department of Microbiology and Immunology Faculty of PharmacyBeni-Suef UniversityBeni-Suef Egypt Department of Clinical and Chemical Pathology Faculty of MedicineBeni-Suef UniversityBeni-SuefEgypt Department of Pediatric Medicine Ministry of HealthBeni-Sueft Egypt Ministry of Health Beni-SuefEgypt Department of General Surgery Ministry of HealthBeni-Suefi Egypt Faculty of Agriculture Fayoum University Egypt Clinical Pharmacy Department Faculty of Pharmacy Beni-Suef UniversityBeni-Suef Egypt

Background:The purpose of this study was to evaluate the effectiveness of limited-resource hospitals in managing mild and moderate hospitalized cases of COVID-19 with comorbidities and in preventing their progression to severe ***:Data were obtained from 88 moderate COVID-19 patients with comorbidities who were admitted to limitedresource *** data were classified into several parts:comorbidities,chronic medication before hospital admission,symptoms of COVID-19 before and during hospitalization,clinical features,laboratory findings on hospital admission,complications during hospitalization,as well as worst laboratory values during hospitalization,hospital stay,and *** clinical features,laboratory results,type of oxygen therapy used,and the final treatment outcome were all evaluated to assess for any potential ***:All patients were alive upon *** admission,the majority of patients(60.2%)received COVID-19 treatment,and the average hospital stay was 12 *** most common symptoms were fever(88.7%),cough(95.5%),shortness of breath(90.9%),myalgia(84.1%),confusion(63.6%),headache(62.5%),sore throat(88.7%),rhinorrhea(17%),chest pain(58%),diarrhea(19.3%),nausea and vomiting(38.6%),anosmia(62.5%),as well as dysgeusia(64.8%).Based on chest radiograph or computed tomography(CT)scan,9.1%of the patients had unilateral pneumonia,90.9% had bilateral pneumonia,and 96.6% had multiple mottling and ground-glass *** was found associated with a significant increase in headache(p=0.005),rhinorrhea(p=0.013),chest pain(p=0.007),and the need for positive airway pressure(p=0.008).Between pre-and post-hospital admissions,there was a significant increase in lactate dehydrogenase and ferritin but a decrease in platelet,D-dimer,hemoglobin,lymphocytes,neutrophils,and total leucocyte count(p<0.001).There was a significant association between hospital stay and D-dimer level(p=0.05).Conclusion:Limited-resource hospitals in Egypt w

关键词： COVID-19 Limited-resource hospitals COVID-19 laboratory tests Comorbidities

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