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Open Journal of Urology 2018年第9期8卷 267-274页

作者： Sumba Harrison Abdelouahed Lasri Youness Jabbour Amine Slaoui Jacquet Djamal Tariq Karmouni Kadir el Khader Abdelatif Koutani Ahmed Ibn Attiya Andaloussi Department of Urology “B” Ibn Sina University Hospital Rabat Morocco Faculty of Medicine and Pharmacy Mohamed V University Rabat Morocco Department of Uro-Andrology Faculty of Health Sciences Cotonou Benin

Obstructive acute renal failure is both a medical and a surgical emergency. The first treatment modality is urological by relief of obstruction. Post-obstructive diuresis is an abnormal condition of prolonged polyuria, involving both excessive solute and water loss, after acute drainage of obstructed urinary tract system. Physiopathology mechanisms are multiples. In most patients, diuresis will resolve once the kidneys normalize the volume and solute status and homeostasis is achieved. Post-obstructive diuresis can occur in up to 50% of patients with substantial urinary tract obstruction and can be life-threatening if it becomes pathologic. It can be detected by hourly monitoring of diuresis. Medical treatment of post-obstructive diuresis consists of oral or intravenous fluids adjusted to the findings of clinical examination, diuresis (volume and electrolytes) and close monitoring of patient. Fluid compensation should be tapered off over several days. Patients at high risk of post-obstructive diuresis should be identified and appropriately monitored.

关键词： Post-Obstructive Diuresis Acute Renal Failure Water and electrolyte Compensation

Cystitis Glandularis: A Rare Benign Condition Presenting as Bladder Tumor

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Open Journal of Urology 2018年第12期8卷 336-343页

作者： Sumba Harrison Hamza Lamchahab Jacquet Djamal Youness Jabbour Touzani Alae Tariq Karmouni Kadir el Khader Abdelatif Koutani Ahmed Ibn Attiya Andaloussi Department of Urology “B” Ibn Sina University Hospital Rabat Morocco Faculty of Medicine and Pharmacy Mohamed V University Rabat Morocco Department of Uro-Andrology Faculty of Health Sciences Cotonou Benin

Cystitis glandularis or glandular metaplasia of the urinary bladder, is a benignreactive metaplasia of the urothelium, which occurs in the context of chronic irritation, in less than 2% of the general population. It is a condition in most casesasymptomatic, but also characterized by nonspecific symptoms and paraclinical findings, which is why this condition is underdiagnosed. Its evolution is mainly focused on the risk of malignant degeneration. This condition affects men much more commonly than women. Two forms of cystitis glandularis are recognized: typical and intestinal form. They differ in their histology, incidence, difficulty of diagnosis, and possible association with adenocarcinoma of the bladder. Diagnosis of certainty is histological by careful analysis of chips from bladder endoscopic resection. This rare pathology is managed by endoscopic bladder resection, with repeated cystoscopy as a monitoring tool. Extensive surgical is needed in severe or recurrent cases. We present here-in a case of a female patient having cystitis glandularis presenting with lower urinary tract symptoms. We review equally data reported in literature. To the best of our knowledge our case represents the fourth case of cystitis glandularis affecting a female patient reported in the English literature so far.

关键词： Cystitis Glandularis Cystoscopy Bladder Resection

Management of Pregnant Women with Invasive Cervical Cancer about Ten Cases

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Journal of Cancer Therapy 2018年第9期9卷 740-754页

作者： K. Diabaté H. Bakkali A. Lachgar S. Nadir T. Kebdani B. K. el Gueddari N. Benjaafar Radiotherapy Department National Institute of Oncology Mohamed V University Rabat Morocco

The purpose of this study was to update the management of invasive cervical cancers diagnosed during pregnancy. Patients and methods: This study was performed retrospectively at radiotherapy department of National Institute of Oncology Rabat Morocco. From 01/04/2005 to 31/05/2010, ten patients with invasive cervical cancer during pregnancy were included. Results: Ten patients were included in the study. The staging was as follow: stage IIIB (n = 4);stage IIB (n = 2) and stage IB2 (n = 4). The radical abdominal hysterectomy with pelvic lymphadenectomy was performed in five patients;a therapeutic interruption of pregnancy was performed in four patients. One pregnancy has resulted in the birth of a living child (by cesarean section). Adjuvant treatment was concomitant chemoradiotherapy followed by low dose rate (LDR) brachytherapy in three patients;adjuvant concomitant chemoradiotherapy followed by high dose rate (HDR) brachytherapy was performed in four patients;a HDR brachytherapy was done in one patient. Two patients have received an exclusive external radiotherapy. After a median follow-up of 4 years (2 - 7 years), there were bone and lung metastases in one patient. Nine patients are alive after completed treatment. Conclusion: Our series focused on ten patients with invasive cervical cancer during pregnancy. Management is complex and requires discussion in a multidisciplinary meeting. Routine screening of cervical cancer and awareness are the key point to improve the treatment and survival rate of patients. The management of all cases is according to international recommendations.

关键词： Cervical Cancer Pregnancy Treatment

Artificial Neural Networks Applied to Landslide Susceptibility Mapping in the Northern Area of the Central Rif(Morocco)

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地学前缘 2009年第S1期16卷 64-64页

作者： M.Amharrak J.el khattabi B.Louche L.Asebriy E.Carlier Earth Sciences Department Faculty of SciencesMohamed Premier University Mechanical laboratory of Lille University of Sciences and technologies of Lille Earth Sciences Department Scientific instituteB.P.703Mohammed V-Agdal University

Recently,Artificial Neural Networks(ANNs)have been used for various scientific and engineering applications essentially because they allow the modeling of a process,which starts from the database containing the variables that describe that particular *** have already been applied to the study of landslides in particular,with reference to the indirect determination of the triggering

关键词： Landslide susceptibility statistical approach artificial neural network Central Rif

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Extraprofessional and Occupational Risk Factors for Colorectal Cancer

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Journal of Life Sciences 2012年第8期6卷 848-857页

作者： Olfa el Maalel Wided Boughattas Maher Maoua Houda Kalboussi Iheb Bougmiza Houssem Rhif Souhaiel Chatti Kader N'Daye Faten Debbabi Ali Mtiraoui Noejib Mrizak Department of Occupational Medicine Teaching Hospital Farhat Hached of Sousse Avenue Ibn El Jazzar 4000 Tunisia Department of Communal Medicine Medicine University Avenue Mohamed Karoui Sousse 4002 Tunisia

Colorectal cancers （CRC） account for frequent and serious cancers which result from the interaction between individual genetic factors and environmental factors, and in particular widely studied nutritional ones. The role of other occupational factors remains a controversial subject. The objective of this study is to evaluate the possible impact of occupational factors on the risk of developing CRC. Materials and Methods： This is a retrospective case-control study. The cases and the control group were enlisted in the general surgical ward of Farhat Hached Teaching Hospital of Sousse （Tunisia） during the period extending from 2004 to 2008, and they were age and gender-matched. The data were analyzed using SPSS 11.0 software with a signification threshold fixed at 5%. A univariate analysis was carried out as well as a multiple binary logistical regression. Results： During the period of the study, 40 cases of colorectal cancers have been colligated including 28 men and 12 women with a sex ratio of 0.43. The average age of the cases was 61.55 ± 13.3 years and 60.40 ± 12.84 years for the control group, with a non significant difference （P = 0.69）. The univariate analysis has objectivized significant associations between colorectal cancer and the housing conditions, the neoplastic and digestive family history, the occupational activity sector, exposure to pesticides, and lack of periodic medical supervision. After logistical regression, the occurrence risk of CRC was significantly associated with： alcohol and smoking （ORa = 3.43; Pa = 0.05）, meat consumption （ORa = 3.34; Pa = 0.03）, exposure to pesticides （ORa = 20.44; Pa = 0.012） and lack of periodic medical supervision （OR = 7.45; P = 0.004）. Conclusion： The occupational risk factors might play a role in the etiopathogenesis of colorectal cancers. With regard to our study, pesticides seem to be most implicated and necessitate suitable preventive measures. Nevertheless, it seems useful to multiply the studies to a much l

关键词： Colorectal cancer occupational risk factors extraprofessional factors epidemiology.

Genetic Polymorphisms of HBS1L-MYB (rs4895441 and rs9376090) in Egyptian Patients with Hemoglobinopathy

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Open Journal of Blood Diseases 2020年第4期10卷 89-100页

作者： Thoria A. Omar Emad F. Abd-elhalim Rawhia H. eledel mohamed A. Soliman Fatma S. Ebeid Ola H. elshafey Dalia H. Abou-elela Clinical Pathology Department Faculty of Medicine Menoufia University Shibin El Kom Egypt Pediatric Department Faculty of Medicine Ain Shams University Ain Shams Egypt

Objective: Study the HBS1L-MYB (rs4895441 and rs9376090) genetic polymorphisms in Egyptian patients with β-thalassemia major and sickle cell disease and its relation to Hb F and severity of the disease. Background: Hb F is a predominant modulator for the severity of β-thalassemia major & sickle cell disease. Genetic polymorphism in the intergenic region (HBS1L-MYB) between GTP-binding elongation factor HBS1L and myeloblastosis oncogene MYB on chromosome 6q is associated with high fetal hemoglobin levels. Subjects and Methods: 150 subjects were included in this study. For all studied groups: Complete blood picture and serum ferritin were evaluated. For patients, hemoglobin variants were separated by High-performance liquid chromatography. Genotyping of HBS1L-MYB (rs4895441 & rs9376090) was evaluated by real-time polymerase chain reaction technique using TaqMan probe. Results: AG, CT genotypes, and G, C alleles of HBS1L-MYB (rs4895441 & rs9376090) were significantly high in sickle cell patients [OR (3.400);95% C.I (1.482 - 7.799)], (p = 0.003) & [OR (4.522);95% C.I (1.854 - 11.029)], (p = 0.001) respectively. Also, a significant association was detected between polymorphisms and disease severity. However, in β

Cost Effectiveness Analysis of Filgrastim versus Placebo in Post AIIogentic Bone Marrow Transplantation

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Journal of Pharmacy and Pharmacology 2016年第6期4卷 268-272页

作者： Maoudoud Ines Razgallah Khrouf Myriam Ben Abdejelil Nour Ghedira Hela Amel Lakhal Marsit Hanene Turki Manel Soussi mohamed Ali Lazreg Olfa Ladab Saloua Ben Othmane Tarek University of Monastir Faculty of Pharmacy-5000 Tunisia Centre National de Greffe de Moelle Osseuse-1006 Tunisia University of Tunis el Manar Faculty of Medicine of Tunis-1006 Tunisia

Filgrastim is used to accelerate hematopoietic recovery after ABMT （allogeneic bone marrow transplantation）. Its impact on the total cost of patient care remains to be explored. We therefore undertook a cost effectiveness analysis in the context of a randomized single blinded clinical trial of Filgrastim versus placebo in post ABMT. A primary endpoint, duration of myelosuppression, and three secondary end points （number of days of fever, length of hospital stay, survival at one hundred days） were used to assess efficacy. Direct costs were evaluated and allowed the calculation of the ICER （incremental cost-effectiveness ratios） for the major endpoint of the trial. Sixteen patients were included in the study. The duration of myelosuppression was significantly decreased in the Filgrastim arm with medians of 15 days vs. 19 days in the placebo arm （p = 0.023）. Cost analysis showed no statistically significant difference between the two arms. According to the calculation of ICER, Filgrastim was more costly and more effective than placebo for the number of days of aplasia avoided and the number of days with fever avoided. Placebo strictly dominated filgrastim for days of hospitalization avoided. Filgrastim has proven effective in reducing the duration of aplasia without increasing costs.

关键词： Filgrastim placebo cost effectiveness allogeneic bone marrow transplantation.

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阿尤恩技术学院,阿尤恩,摩洛哥

世界建筑 2020年第4期 52-57,126,127页

作者：萨德·卡巴吉德里斯·凯塔尼穆罕默德·阿明·辛那王欣欣(译) 萨德·卡巴吉建筑事务所德里斯·凯塔尼建筑事务所辛那建筑事务所不详

位于摩洛哥的阿尤恩技术学院项目是摩洛哥针对不同区域大学城去中心化政策的一部分。功能包括教学空间(教室、工作室、阶梯教室)、图书馆、行政办公室、教师办公室和服务空间(维修空间、职工宿舍等)。基地远离市中心,有对于"城市性"的需... 详细信息

位于摩洛哥的阿尤恩技术学院项目是摩洛哥针对不同区域大学城去中心化政策的一部分。功能包括教学空间(教室、工作室、阶梯教室)、图书馆、行政办公室、教师办公室和服务空间(维修空间、职工宿舍等)。基地远离市中心,有对于"城市性"的需求,借由轴心方案的形式,提供了一种综合性的清晰的解读方式和多样化的氛围。不同建筑体分散排布,以确保最大化的自然通风和日照。

关键词：教师办公室去中心化阶梯教室职工宿舍教学空间大学城图书馆自然通风

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空间钢结构和组合型半刚性节点的试验及数值模型

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钢结构(中英文) 2009年第9期 87-87页

作者： mohamed A.Dabaon Mahmoud H.el-Boghdadi Omnia F.Kharoob

对空间钢结构和组合型半刚性节点进行试验以研究其性能。考虑半刚性节点从次轴向主轴加载的效应。对半刚性空间钢结构和组合外伸端板节点进行5个足尺试验。利用ANSYS构建三维有限元模型对其进行分析研究。对现有数值模型和试验结果进行... 详细信息

对空间钢结构和组合型半刚性节点进行试验以研究其性能。考虑半刚性节点从次轴向主轴加载的效应。对半刚性空间钢结构和组合外伸端板节点进行5个足尺试验。利用ANSYS构建三维有限元模型对其进行分析研究。对现有数值模型和试验结果进行对比,以验证模型的有效性。同时,通过在空间结构上采用梁单元模型来研究节点刚度,这一效应已经被前面的研究所证实。

关键词：试验研究半刚性节点次轴主轴有限元建模空间结构

Embedding tin disulfide nanoparticles in twodimensional porous carbon nanosheet interlayers for fast-charging lithium-sulfur batteries

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Science China Materials 2021年第11期64卷 2697-2709页

作者： Na Zhou Wen-Da Dong Yun-Jing Zhang Di Wang Liang Wu Lang Wang Zhi-Yi Hu Jing Liu Hemdan S.H.mohamed Yu Li Li-Hua Chen Bao-Lian Su State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China Nanostructure Research Center(NRC) Wuhan University of TechnologyWuhan 430070China Physics Department Faculty of ScienceFayoum UniversityEl Gomhoria Street63514 FayoumEgypt Laboratory of Inorganic Materials Chemistry(CMI) University of Namur61 rue de BruxellesB-5000 NamurBelgium

Lithium-sulfur(Li-S)batteries have attracted significant attention for their high specific capacity,non-toxic and harmless ***,the shuttle effect limits their *** this work,small-sized tin disulfide(SnS_(2))nanoparticles are embedded between interlayers of twodimensional porous carbon nanosheets(PCNs),forming a multi-functional nanocomposite(PCN-SnS_(2))as a cathode carrier for Li-S *** graphitized carbon nanosheets improve the overall conductivity of the electrode,and the abundant pores not only facilitate ion transfer and electrolyte permeation,but also buffer the volume change during the charge and discharge process to ensure the integrity of the electrode *** importantly,the physical confinement of PCN,as well as the strong chemical adsorption and catalytic reaction of small SnS_(2)nanoparticles,synergistically reduce the shuttle effect of *** interaction between a porous layered structure and physical-chemical confinement gives the PCN-SnS_(2)-S electrode high electrochemical *** at a high rate of 2 C,a discharge capacity of 650 mA h g^(-1)is maintained after 150 cycles,underscoring the positive results of SnS_(2)-based materials for Li-S *** galvanostatic intermittent titration technique results further confirm that the PCN-SnS_(2)-S electrode has a high Li+transmission rate,which reduces the activation barrier and improves the electrochemical reaction *** work provides strong evidence that reducing the size of SnS_(2)nanostructures is beneficial for capturing and reacting with polysulfides to alleviate their shuttle effect in Li-S batteries.

关键词： tin disulfide nanoparticles porous carbon nanosheets lithium-sulfur batteries galvanostatic intermittent titration technique density functional theory

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