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Functional and anatomical evaluation of the effect of nepafenac in prevention of macular edema after phacoemulsification in diabetic patients

全国第八届有机固体电子过程暨华人有机光电功能材料学术讨论会

作者：庄小东陈彧 mohamed e.ei-khouly Ling Qidan Shunichi Fukuzumi Kand entang 教育部结构可控先进功能材料及其制备重点实验室华东理工大学化学与分子工程学院 Department of Material and Life Science Graduate School of EngineeringOsaka University Department of Chemical and Biomolecular engineering National University of Singapore

设计和制备具有光诱导电荷转移特征的推-拉型高分子光电功能材料,探索材料在光电转换和分子电子器件中的应用是目前国际上研究热点之一。我们合成了一种新型分散红终端的推拉型高分子光电功能材料DR1-PDPAF-DR1(图1),该材料具有很高的...

设计和制备具有光诱导电荷转移特征的推-拉型高分子光电功能材料,探索材料在光电转换和分子电子器件中的应用是目前国际上研究热点之一。我们合成了一种新型分散红终端的推拉型高分子光电功能材料DR1-PDPAF-DR1(图1),该材料具有很高的热稳定性、优异的空穴传输性能、高效的电荷分离过

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International Journal of Ophthalmology(english edition) 2019年第3期12卷 387-392页

作者： Tharwat Mokbel Sameh Saleh Mona Abdelkader Sherief e.el-khouly Waleed Abou Samra mohamed Mamdouh Mansoura Ophthlmic Center Faculty of Medicine Mansoura University

AIM: To evaluate the effect of prophylactic administration of nepafenac in prevention of macular edema occurring in diabetic patients after phacoemulsification and to investigate the correlation between optical coherence tomography(OCT) foveal thickness and multifocal electroretinogram(MF-eRG) ***: The study included two groups. Group 1 included 50 diabetic patients with senile cataract(50 eyes, 30 females, 20 males, aged 55±7 y) re.eived nepafenac 0.1% eye drop. Group 2 included another 50 diabetic patients with senile cataract(50 eyes, 22 female, 28 males, aged 53.8±8 y) did not re.eive nepafenac. All patients were followed up for 3 mo postoperatively. OCT and MF-eRG were done preoperative and at 1 wk, 1, 2 and 3 ***: The mean foveal thickness was statistically significantly lower in Group 1. Five eyes in Group 2 developed clinical cystoid macular oedema(CMO)(10%), and no patients in Group 1 developed central macular thickening more than 50 μm. There were insignificant differences in MF-eRG amplitudes and latencies between the two groups except in the five eyes that developed CMO, there statistically significant reduction of MF-eRG amplitude with increase in foveal thickness. CONCLUSION: Perioperative nepafenac reduces the incidence of CMO following uncomplicated phacoemulsification significantly. Nepafenac has no side effects.

关键词： nepafenac macular edema cataract surgery diabetes optical coherence tomography multifocal electroretinogram

Facile Synthesis of Naphtho[2,3-dJthiazoles, Naphtho[2,3-e]-[1,3,4]thiadiazines and Bis（naphtho[2,3-d]thiazolyl）copper（ll） Derivatives from Heteroylthiosemicarbazides

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Chinese Journal of Chemistry 2016年第8期34卷 814-822页

作者： Alaa A. Hassan Nasr K. mohamed Lamiaa e. Abd ei-Haleem Stefan Brase Martin Nieger Chemistry Department Faculty of Science Minia University 61519 EI-Minia A. R. Egypt Institute of Organic Chemistry Karlsruhe Institute of Technology Fritz-Haber-Weg 6 76131 Karlsruhe Germany Laboratory of Inorganic Chemistry Department of Chemistry University of Helsinki P.O.Box55 (A. I. Virtasenaukio 1) 00014 Helsinki Finland

A one step synthesis protocol for the conversion of heteroylthiosemicarbazides and 2,3-dichloro-1,4-naphthoquinone to naphtho[2,3-d]thiazoles, naphtho[2,3-e][1,3,4]thiadiazines as well as bis(naphtho[2,3-d]thiazolyl)copper(II) derivatives is described. The products were conclusively confirmed by single crystal X-ray analyses. A mechanism for the formation of the products is presented.

关键词： heteroylthiosemicarbazides 2 3-dichloro-1 4-naphthoquinone naphtho[2 3-d]thiazoles naphtho[2 3-e][1 3 4]thiadiazines bis(naphtho[2 3-d]thiazolyl)copper(II) derivatives

electroconductive Composites Containing Nanocellulose,Nanopolypyrrole,and Silver Nanoparticles

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Journal of Renewable Materials 2019年第2期7卷 193-203页

作者： Samir Kamel Ahmed A.Haroun Amany M.ei-Nahrawy mohamed A.Diab Cellulose and Paper Department National Research Centre33 El Bohouth st.Dokki GizaP.O.12622Egypt Industrial Research Division National Research Centre33 El Bohouth st.Dokki GizaP.O.12622Egypt Solid State physics Department Physics Research DivisionNational Research Centre33 El Bohouth st.Dokki GizaP.O.12622Egypt

In this work,conducting composites of nanocellulose(NC)/polypyrrole nanoparticles(NPPy)and silver nanoparticles(AgNPs),i.e.,NC/NPPyAg,were synthesized for the first time,to the best of our knowledge,via in situ emulsion polymerization of pyrrole in the presence of surfactant *** AgNPs acted as an oxidizing agent to simultaneously incorporate nanoparticles into the prepared *** structures and morphologies of the prepared composites were studied using Fourier transform infrared(FTIR)spectroscopy,X-ray diffraction(XRD),UV-Vis Spectra,thermogravimetric analysis(TGA),and scanning and transmission electron microscopy(SeM and TeM)***,the prepared composites were characterized by their conductivities,and the dielectric constants(e΄),dielectric losses(e˝),and AC conductivities were studied for the prepared composites with an increasing NPPy content as a function of the frequency.

关键词： Nanocellulose nanopolypyrrole emulsion polymerization silver nanoparticles conductive nanocomposites

exploring dynamic biomedical algorithm of eurycoma longifolia Jack and its bioactive phytochemicals: A review of pharmacokinetic and pharmacodynamic implications and future prospects

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Asian Pacific Journal of Tropical Medicine 2018年第2期11卷 89-97页

作者： Hnin ei Thu Zahid Hussain Isa Naina mohamed Ahmad Nazrun Shuid Department of Pharmacology Faculty of MedicineUniversity Kebangsaan Malaysia(The National University of Malaysia) Department of Pharmaceutics Faculty of PharmacyUniversiti Teknologi MARAPuncak Alam Campus

eurycoma longifolia Jack(***) is a well-recognized traditional herbal medicine that offers a wide dynamic range of biomedical applications including anti-osteoporotic, anticancer, anti-proliferative, anti-malarial, antimicrobial, antioxidant, aphrodisiac, antiinflammatory, anxiolytic, anti-diabetic, anti-rheumatism and anti-ulcer *** review aims to overview the pharmacokinetic and a pharmacodynamic algorithm of *** and its bioactive *** of pharmacokinetic profile revealed that *** exhibit higher bioavailability, high volume of distribution, slow elimination rate, and does not show inhibitory effects on cytochrome P450 *** has been used, alone or in combination with other pharmacological agents, in the form of crude extracts, standard extracts, or decoctions of different plant parts(i.e., herbs, shrubs, stem, leaves, and roots) for the treatment of various ailments in animals and *** various bioactive constituents, eurycomanone has been found to be the most remarkable, super-stable, versatile, and most potent phytochemical(isolated or extracted from root extracts) against various types of animals and human *** on its well-established pharmacokinetic and pharmacodynamic profiles, we suggested that *** can be a well-accepted complementary and alternative medicine for the treatment of different types of human ailments.

关键词： eurycoma longifolia Jack Pharmacokinetic profile Pharmacodynamic algorithm eurycomanone Quassinoids

Synthesis of Novel 3-Substituted PyridothienopyrimidineDerivatives with Biological evaluation as Antimicrobial Agents

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Chemical Research in Chinese Universities 2016年第6期32卷 967-972页

作者： Farag A. e1-essawy Nader M. Boshta Ayman K. ei-Sawaf Areal A. Nassar mohamed S. Khalafalah Preparatory Year Deanship Basic Science Department Prince Sattam Bin Abdulaziz University KSA Chemistry Department Faculty of Science Menoufia University Shebin EI-Koam Egypt Collage of Science and Humanitles Prince Sattam Bin Abdulaziz University KSA Faculty of education for Girls Prince Sattam Bin Abdulaziz University KSA

Novel 3-substituted pyridothienopyrimidine derivatives have been synthesized via the reaction of 2-{7,9-dimethyl-4-oxopyrido[3′,2′：4,5]thieno[3,2-d]pyrimidin-3（4H）-yl}acetohydrazide（5） with a variety of activereagents and chemicals. Structures of the newly synthesized compounds were established based on spectral *** resulting pyridothienopyrimidine derivatives were evaluated for their possible antimicrobial activity and some ofthem represent a new class of potentially antimicrobial compounds, especially compounds 9 and 18 which displayedthe highest activity against Gram-positive bacteria, Gram-negative bacteria, and Fungi in MIC range of 0.12--1.95 μg/mL.

关键词： Nitrogen-containing heterocycle Pyridothienopyrimidine Thieno[2,3-b]pyridine Antimicrobial

Physico-Chemical and Biological Studies on Some Complexes of 5-Amino-3-Methylthio-lH-Pyrazol- 4-Carbonitrile

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材料科学与工程（中英文A版） 2012年第9期2卷 610-615页

作者： mohamed Abd ei-Samea elnawawy Chemistry Department Faculty of Science Al-Azhar University Nasr City P.O. Box 11884- Cairo Egypt

Preparation and Characterization of Nanosized Al-MCM-41 Using Different Silica Sources

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Journal of environmental Science and engineering 2010年第4期4卷 21-28页

作者： I.A. Makhlid R.M. mohamed A.A. ei-Midany I.A. Ibrahim e.H. ei-Mossalamy Chemistry Department Faculty of Science King Abdul Aziz university Jeddah KSA Nanostructured Material Division Advanced Materials Department Central Metallurgical R＆D Institute Helwan 11421 CairoEgypt Mining Petroleum Metallurgy Department Faculty of Engineering Cairo University

Silica sources influence different aspects of Al-MCM-41 product. The crystallinity of nanosized Al-MCM-41 zeolites prepared crystallization and lead to change in the properties of the final from precursors mixtures containing different silica sources, e.g. tetraethylorthosilicate （TeOS）, colloidal silica （CS）, silicic acid （SA） and fumed silica （FS） have been studied. The produced samples are investigated using XRD, SeM, FT-IR, pyridine adsorption and N2 physisorption. XRD results show that the products obtained from different silica sources are in Al-MCM-41 phase. SeM results show that silica sources influence the produced Al-MCM-41 shape. Using silicic acid leads to formation of spherical crystals, TeOS gives cubical crystals, colloidal silica forms spherical crystals with smaller aggregated, and fumed silica gives rounded crystals. N2 physisorption results show that silica sources influence pore-diameter and pore-volume of the produced Al-MCM-41 ; the pore diameter of the produced Al-MCM-41 in case of colloidal silica, TeOS, fumed silica, and silicic acid are 12, 20, 15, and 17A respectively. Also, the pore volume of the produced AI-MCM-41 in case of colloidal silica, TeOS, fumed silica and silicic acid are 0.78, 0.71, 0.76, and 0.8 cm^3/gm, respectively.

关键词： Al-MCM-41 preparation silica sources Physico-chemical properties.

Development of Calcium Phosphate Ceramics of Controlled Ca/P Ratio as a Bone Substitute

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材料科学与工程（中英文A版） 2013年第7期3卷 467-474页

作者： Manal Mostafa Awad Medhat Abdelmonem ei-Messiery mohamed Bahgat e1 Kholy engineering Physics Department Faculty of Engineering Cairo University Egypt

In this paper, a study was carried out to produce calcium phosphate ceramics whose composition comes close to that of natural dry bone. Dicalcium phosphate dehydrated (CaHPO4·2H20) and calcium carbonate (CaCO3) were mixed at different proportions so that three batches of ceramics whose Ca/P ratio are 1.5, 1.7 and 1.9 are obtained. These ratios lie in close vicinity to the reported data for dry cortical bone (Ca/P = 1.67). Sintering was carried out at temperatures ranging from 1,100 °C to 1,350 °C. The variation in batch composition as well as in sintering temperature has proved to play a decisive role in determining the end product characteristics. Parameters such as bulk density, porosity, firing shrinkage, modulus of mechanical rupture, mineralogical and textural features behavior, were studied to assess their matching with those of human cortical bone.

关键词：磷酸钙陶瓷 Ca 人工骨可控烧结温度自然干燥磷酸二钙温度范围