检索结果-南通市图书馆

Potential detoxification of aflatoxin B2 using Kluyveromyces lactis and Saccharomyces cerevisiae integrated nanofibers

在线全文

学校读者我要写书评

暂无评论

BIOCelL 2017年第2期41卷 67-73页

作者： MAHMOUD moustafa TAREK TAHA mohamed elNOUBY NEHAL el-DEEB GAMAL HAMAD M.A.ABUSAIED SULAIMAN ALRUMMAN Department of Biology College of ScienceKing Khalid University9004AbhaKingdom of Saudi Arabia(KSA) Botany Department Faculty of ScienceSouth Valley UniversityQenaEgypt Environmental Biotechnology Department Genetic Engineering and Biotechnology Research Institute(GEBRI)City of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab City21934AlexandriaEgypt Composite and Nanostructured Materials Research Department Advanced Technology and New Materials Research InstituteCity of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab City21934AlexandriaEgypt Department of Biopharmaceutical Product Research Genetic Engineering and Biotechnology Research Institute(GEBRI)City of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab City21934AlexandriaEgypt Food Technology Department Arid Land Cultivation Research Institute(ALCRI)City of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab City21934AlexandriaEgypt Polymer Materials Research Department Advanced Technology and New Materials Research InstituteCity of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab City21934AlexandriaEgypt

Current investigation has shown that human exposure to aflatoxins is not limited to the administration of contaminated cereals,but water is another possible *** study was aimed to design easily applicable method to eliminate aflatoxin B2(AFB2)from contaminated drinking *** has been used for preparation of probiotic-coated polyvinyl alcohol(PVA)and cellulose acetate(CA)*** of these hybrid nanofibers were studied by scanning electron microscopy(SEM)and Fourier-transformed infrared spectroscopy(FT-IR).SEM showed the proper coating of probiotic strains(Kluyveromyces lactis CBS 2359 and Saccharomyces cerevisiae ATCC 9763)on both nanofiber *** areas(1-5 cm^(2))of the probiotic-nanofiber hybrid were used to enhance the removal of 20 ng/ml of aflatoxin B2(AFB2)from prepared AFB2-contaminated water over *** revealed that a 5 cm^(2) area of probiotic-coated PVA nanofibers can eliminate 97.5% of AFB2 as compared to 87.5%,90.5%,93.5%,and 95.5%,for 1 cm2,2 cm^(2),3 cm^(2),and 4 cm^(2),respectively,while probiotic-coated CA nanofibers were slightly less ***,the cytotoxicity of probiotics-CA treated water on cultured human fibroblasts was almost 10 times lower than the cytotoxicity recorded in probiotics-PVA treated ***,results of the current research suggest that probiotics-polymer nanofiber membranes can be used as an extra stage in the water purification system for the treatment of AFB2-contaminated water.

关键词： Nanofibers Aflatoxin B2 Cytotoxicity Water treatment

Hepatitis C Virus RNA Strands Detection in Peripheral Blood Mononuclear Cells Legitimizes Virus Eradication in Negative Serum PCR Naive and Post-treatment Patients

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Clinical and Translational Hepatology 2017年第1期5卷 1-8页

作者： mohamed Darwish Ahmed abd Alla Mostafa Kamel el Awady Tropical Medicine Department Faculty of MedicineAl-Azhar UniversityCairoEgypt Department of Microbial Biotechnology National Research CenterCairoEgypt

Background and Aims:Hepatitis C virus(HCV)hepatotropism is associated with intra-peripheral blood mononuclear cell(PBMC)infection that causes post-treatment relapse in RNA seronegative *** understanding of the association of non-viremic hepatic fibrosis with positive anti-HCV IgG antibodies and active hepatocellular damage might be increased by PBMCs screening for intracellular ***,the goals of this study included evaluation of PBMCs PCR for diagnosing HCV infection,addressing PBMCs plus serum real-time(SRT)PCR benefits over SRT-PCR alone,studying intraPBMCs distribution of RNA sense and antisense strands,and identifying treatment feasibility in solitary intracellular ***:Enzyme-linked immunosorbent assay,SRT-PCR and PBMCs PCR were used to evaluate HCV infection in 401 *** patients were classified into groups of negative controls(n=30),positive controls(n=63),non-viremia post-treatment(experienced;n=166)and na(i)ve(n=49)cases,and non-viremia positive PBMCs PCR na(i)ve(n=35)and experienced(n=58)***:The diagnosis of true positive and negative by PBMCs PCR and SRT-PCR had 100%and 96.7%compatibility *** PCR detected intracellular HCV infection in 49 out of 215 non-viremia patients;among them,na(i)ve cirrhotics had significantly higher number of intracellular infection than the na(i)ve non-cirrhotic(Pely recognized in na(i)ve and experienced cases(P=0.01218).Intracellular HCV strands were detected in 18.02%of experienced *** of intracellular RNA strands showed significant decline in experienced compared to na(i)ve patients(Pellular HCV when SRT-PCR is *** and sense strands are respectively recognized more often in na(i)ve and experienced *** expected overall relapsing rate in our cohort was 18.02%.Int

关键词： HCV PBMCs RNA Strands

Burden of pediatric influenza A virus infection post swine-flu H1N1pandemic in Egypt

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Medicine 2013年第9期6卷 693-698页

作者： Adel Khattab Malak Shaheen Terez Kamel Amel el Faramay Safaa abd el Rahman Dalia Nabil mohamed Gouda Influenza Advisory Board Egyptian Ministry of Health Chest Department Faculty of MedicineAin Shams University Pediatrics Department Faculty of MedicineAin Shams University Medical Microbiology and Immunology Department Faculty of MedicineAin Shams University

Objectne:To screen children with influenza like illness or with symptoms of acute respiratory tract infections for influenza A virus infection-post swine flu pandemic era-using rapid influenza diagnostic ***:During two year,(2010&2011),1200 children with influenza like illness or acute respiratory tract infections(according to World Health Organization criteria)were *** ages ranged from 2-60 *** aspirates specimens were collected from all children for rapid influenza A diagnostic ***:Influenza A virus rapid test was positive in 47.5%of the children;the majority(89.6%)were presented with lower respiratory tract *** rate and temperature were significantly higher among positive rapid influenza test ***:Influenza A virus infection is still a major cause of respiratory tract infections in Egyptian *** should be considered in all cases with cough and febrile episodes and influenza like symptoms even post swine flu pandemic.

关键词： Influenza A virus Burden Children Influenza like illness Egypt

Role of Magmatism and Related-Exsolved Fluids during Ta-Nb-Sn Concentration in the Central Eastern Desert of Egypt:Evidences from Mineral Chemistry and Fluid Inclusions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Earth Science 2023年第3期34卷 674-689页

作者： mohamed abd el Monsef Mabrouk Sami Fatma Toksoy‐Köksal Rainer Abart Martin Ondrejka Khaled Mabdelfadil Geology Department Faculty of ScienceTanta University31527 TantaEgypt Geology Department Faculty of ScienceMinia University61519 El-MiniaEgypt Department of Geological Engineering Middle East Technical University06800 AnkaraTurkey Department of Lithospheric Research University of Vienna1090 ViennaAustria Department of Mineralogy Petrology and Economic GeologyComenius UniversityBratislavaSlovakia Department of Geology Faculty of ScienceSohag University82524 SohagEgypt Department of Physics and Earth Sciences Jacobs University28759 BremenGermany

The rare metals of Abu Dabbab area in the Central Eastern Desert of Egypt have been investigated for their mineralogy and conditions of precipitation using combination of EMPA and fluid inclusions studies,in order to delineate the source,mechanism of formation and evolutionary model for these economic ***(Ta-Nb-Sn)-bearing minerals at the Abu Dabbab area include columbite group minerals(CGMs),wodginite and *** both granitic intrusion and its enclosed quartz veins,most of zoned CGMs and cassiterite grains are commonly characterized by a well-developed twostage ***,columbite-(Mn)(CGM-Ⅰ)represents the early formed phase of CGMs that is characterized by high Mn#values(0.64-0.92)with quite low Ta#values(0.13-0.49).It was invaded by Ta-rich phases including tantalite-(Mn)(CGM-Ⅱ;Ta#=0.13-0.49)and wodginite,which contain high Ta_(2)O_(5)and SnO_(2)(17.91 wt.%).In regard to cassiterite,there are distinct compositional differences between the early-phase cassiterite(Cst-Ⅰ)and the late-phase one(Cst-Ⅱ),where the latter is enriched in Ta_(2)O_(5),Nb_(2)O_(5)and *** chemistry and textural criteria of the early stage CGM-Ⅰand Cst-Ⅰ,all are indicative of magmatic ***,the latter CGM-Ⅱ,wodginite and Cst-Ⅱwere influenced by the late magmatic Ta-rich *** inclusions microthermometry shows criteria of phase separation represented by both boiling and fluid *** initial fluid was supposed to be of magmatic origin(magmatic CH4),that was consequently influenced by fluid mixing/dilution with post-hydrothermal/meteoric water with respect to the decompression process during *** construction gave rise to an estimate P-T conditions(T=330-370℃,P=22-50 MPa).The fluid inclusions’microthermometry supports a transition between magmatic and late to post-hydrothermal activities in addition to surface-derived fluid(meteoric fluid?)in a part as main source for the polymetallic deposits.

关键词： columbite-group minerals wodginite cassiterite magmatic-hydrothermal fluid inclusion deposits Abu Dabbab

Micropunch grafting for healing of refractory chronic venous leg ulcers

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Plastic and Reconstructive Surgery 2022年第4期4卷 166-170页

作者： Aya mohamed Samy Mostafa abd el-Halim Ahmed Hassan el-Sabbagh Department of Plastic and Reconstructive Surgery Mansoura University HospitalMansoura 35516Egypt Plastic Surgery Center Faculty of MedicineMansoura UniversityMansoura 35516Egypt

Background: Chronic venous ulcers are a serious problem for both patients and physicians. The CEAP classification(clinical manifestations(C), etiologic factors(E), anatomic distribution of disease(A), and underlying pathophysiologic findings(P)) for chronic venous disorders(CVD) was developed in 1994. Published papers on CVD use all or part of the CEAP. Micropunch grafts, which are a variation of skin grafts, have been used with great success in plastic surgery for both esthetic and reconstructive purposes. This study aimed to assess the outcomes of micropunch grafting in the treatment of chronic refractory venous ***: Patients with chronic venous ulcers who did not respond to conservative treatment for more than 6months were included in the study. All patients underwent ulcer coverage by micropunch skin grafts using a micrometer. The patients were discharged on the same day as the surgery. Micropunch skin grafts were manually counted per square centimeter intraoperatively and during follow-up using Dermlite DermatoschopeTM II Pro *** satisfaction was assessed by using a ***: Twenty patients underwent the surgery. Most of the patients were middle-aged males. The ulcers were predominantly small-and medium-sized. The mean operation time was 167.00 ± 86.01 min. After 6 months, the survival rate of the planted micrografts was 84%. Three ulcers had graft loss and two patients had an infection at the ulcer site, which was managed conservatively. The patients were followed-up for 14 ***: Micropunch grafting is a useful and convenient method for the treatment of difficult venous ulcers and can be performed on an outpatient basis.

关键词： Venous ulcer Micropunch grafting

A comparative study of liquid and solid inner contact roxatidine acetate ion-selective electrode membranes

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2015年第6期26卷 714-720页

作者： mohamed K.abd el-Rahman Hala E.Zaazaa Samah S.Abbas Badr el-Zeany Zeinab A.el-Sherif Dalia A.el-Haddad Analytical Chemistry Department Faculty of PharmacyCairo University National Organization for Drug Control and Research

A comparative study was conducted using two designs of a roxatidine acetate （ROX）-selective electrode; a conventional liquid inner contact called electrode A and a graphite-coated solid contact called electrode 13. The fabrication of electrodes was based on roxatidine-tetraphenylborate （ROX-TPB） as an ion-association complex in a PVC matrix using different plasticizers. electrode A has a linear dynamic range of 2.2 ×10^-5 mol/L to 1.0 ×10^-2 mol/L, with a Nernstian slope of 54.7 mV/decade and a detection limit of 1.4 ×10^-6 mol/L. electrode B shows linearity over the concentration range of 1.0×10^-6 mol/L to 1.0×10^-2 tool/L, with a Nernstian slope of 51.2 mV/decade and a limit of detection of 1.1×10^7 mol/L which is remarkably improved as a result of diminishing ion fluxes in this solid contact, ion-selective electrode. The proposed sensors display useful analytical characteristics for the determination of ROX in bulk powder and its pharmaceutical formulation. The present electrodes show clear discrimination of ROX from several inorganic, organic ions, sugars, some common drug excipients and the degradation product （3-[3-（1-piperidinyl methyl） phenoxy] propyl amine） of ROX. Furthermore, the proposed electrodes were utilized for the determination of ROX in human plasma, where electrode B covers drug Cmax which indicated its applicability to pharmacokinetic, bioavailability and bioequivalent studies. The results obtained by the proposed electrodes were statistically analyzed and compared with those obtained by a reported HPLC method. No significant difference for either accuracy or precision was observed.

关键词： Comparative study Roxatidine acetate Liquid inner contact electrode Solid contact electrode Degradation product Plasma

Structural Development of Northwest Saudi Arabia Using Aeromagnetic and Seismological Data

在线全文

学校读者我要写书评

暂无评论

Journal of Earth Science 2016年第6期27卷 998-1007页

作者： mohamed Fnais elkhedr Ibrahim Essam abd el-Motaal Kamal abdelrahman abdelmaguid Al-Heniedi Khaled Al-Kahtany Department of Geology and Geophysics King Saud University Riyadh 36002 KSA Department of Geology Faculty of Science Mansoura University Mansoura 21345 Egypt Department of Geology Faculty of Science Al-Azhar University Cairo 11435 Egypt Department of Seismology National Research Institute of Astronomy and Geophysics Cairo 11435 Egypt

High resolution aeromagnetic and seismological data constrained by field-based structural investigations have been used to map and delineate the structural elements that affected and shaped the Midyan area in the northwest part of Saudi Arabia. The area was divided into four major domains defined by NNE, NNW, NW and ENE trending faults identified by trends, patterns and intensity of magnetic anomalies. The ENE trending left-lateral strike-slip faults intersected by NNE trending faults are the predominant tectonic features in the Gulf of Aqaba coastal area and stop at the boundary of a central domain characterized by complexity in the pattern and intensity of magnetic anomalies, that may be attributed to heterogeneity of basement rocks containing complex igneous rock suites including diorite, gabbro, ultramafic and alkali granitic rocks. This domain is characterized by the presence of narrow linear magnetic anomalies that extend for kilometers in an NNW direction, indicating dikes intruded through NNW trending faults. These dikes become WNW-oriented near their northern termination by transfer of movement to WNW-oriented faults marking the northern termination of the Red Sea rift. It is believed that this fault zone is still experiencing neotectonic activity, as evident from recorded seismicity. The aeromagnetic structural resuits coincide with fault plane solutions for the largest earthquakes, confirming aeromagnetic interpreted trends and illustrating mixed mechanisms between extensional and strike-slip faulting. Thus the study area displays different mechanisms associated with different tectonic trends which show clearly in the structural patterns of the area.

关键词： aeromagnetism seismicity neotectonics Midyan area Saudi Arabia.

Isolation, purification and structure elucidation of three newbioactive secondary metabolites from Streptomyces lividans AM

在线全文

学校读者我要写书评

暂无评论

BIOCelL 2021年第5期45卷 1263-1271页

作者： MOHAMMAD el-METWALLY MAMDOUH abdel-MOGIB MANAL elFEDAWY GAAD SOHSAH AHMED REZK MAHMOUD moustafa mohamed SHAABAN Botany and Microbiology Department Faculty of ScienceDamanhour UniversityDamanhour22511Egypt Chemistry Department Faculty of ScienceMansoura UniversityEl-Mansoura35516Egypt Bioprocess Development Department Genetic Engineering and Biotechnology Research InstituteCity of Scientific Research and Technological Applications(SRTA-City)New Borg El-Arab CityAlexandria21934Egypt Biology Department College of ScienceKing Khalid UniversityAbha9004Saudi Arabia Chemistry of Natural Compounds Department Division of Pharmaceutical IndustriesNational Research CentreDokki-Cairo12622Egypt Organic and Bioorganic Chemistry Department of ChemistryBielefeld UniversityBielefeld33615Germany

Microorganisms are a huge mine of bioactive metabolites,and actinomycetes are one of the very active groups in this *** this article,we are concerned about the full taxonomical characterization of Streptomyces lividans AM,isolated from Egyptian *** isolate produced three new bioactive metabolites,namely:1-Nona-decanoyl,4-oleyl disuccinate(1),filoboletic acid;(9Z,11E)-8,13-dihydroxy octadeca-9,11-dienoic acid(2),and sitosteryl-3β-D-glucoside(3).Extensive 1D and 2D NMR and HR-mass spectrometry were used to elucidate the structures of the three ***,ten known compounds were also *** antimicrobial activity of the producing organism and newly reported compounds(1–3)was investigated against a selected group of pathogenic microorganisms.A full taxonomical characterization of the strain was described as well.

关键词： Bioactive metabolites Streptomyces sp. Taxonomy Biological activity

Application of GC/EIMS in Combination with Semi-Empirical Calculations for Identification and Investigation of Some Volatile Components in Basil Essential Oil

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Analytical Mass Spectrometry and Chromatography 2016年第1期4卷 14-25页

作者： Mamoun S. M. abd el-Kareem mohamed abd el fattah Rabbih Ezzat Taha mohamed Selim elsherbiny abd el-monem elsherbiny Ayman Yasen el-Khateeb Molcular and Atomic Physics Unit Experimental Nuclear Physics Dept. Nuclear Research Centre Egyptian Atomic Energy Authority Inshas Cairo Egypt Plant Pathology Department Faculty of Agriculture Mansoura University Mansoura Egypt Agricultural Chemistry Department Faculty of Agriculture Mansoura University Mansoura Egypt

Volatile components in the extracts of basil leaves (Ocimum basilicum L.) were identified by gas chromatography/mass spectrometry (GC/MS) with electron ionization (EI) mode. The major volatile components of basil under investigation are α-pinene, sabinene, β-pinene, d-limonene, eucalyptol, l-linalool and estragole. electron ionization mass spectra of these compounds have been obtained and investigated. Furthermore, the semi-empirical MNDO [Modified Neglect of Diatomic Overlap] method was used to calculate the thermochemical data for the structural properties of these compounds.

关键词： Gas Chromatograph Mass Spectrometer Semi-Empirical Calculations Basil Essential Oil