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Open Journal of Veterinary Medicine 2018年第10期8卷 175-185页

作者： mohamed Jafar Al-hassan Department of Animal Production College of Food and Agriculture Sciences King Saud University Riyadh Saudi Arabia

Heat stress is identified as a major cause of lower productive and reproductive performance in animal farming. This situation is more common in Saudi Arabia than in other countries because of extremely high ambient temperatures experienced during the summers. The evaporative cooling cow group had significantly increased serum E2 concentrations on days 7 and 14 - 19 of their estrous cycles, and significantly decreased serum P4 concentrations on days 7 - 18 of their estrous cycles. Evaporative cooling plus shade lowered ambient temperatures (41.80 ± 0.74 versus 47.40?C ± 0.84?C) have increased the relative humidity (0.33 ± 0.01 versus 0.24 ± 0.01) and decreased the temperature humidity index (80.24 ± 0.60 versus 84.77 ± 0.68) when compared with shade alone. However, cows under shade alone, compared to cows under evaporative cooling with shade, had a larger number of small (10.04 ± 0.54 versus 4.72 ± 0.58), medium (2.80 ± 0.21 versus 1.79 ± 0.17), and large follicles (6.82 ± 0.28 versus 5.66 ± 0.22). These results demonstrated that while evaporative cooling had positive effects on dairy cows in this experiment, changes could have been more profound, if installations of curtains and fans were implemented, which might need further investigation.

关键词： Evaporative Cooling Folliculogenesis Heat Stress E2 and P4

Navigating challenges and opportunities of machine learning in hydrogen catalysis and production processes: Beyond algorithm development

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Journal of Energy Chemistry 2024年第12期99卷 223-252页

作者： Mohd Nur Ikhmal Salehmin Sieh Kiong Tiong hassan mohamed Dallatu Abbas Umar Kai Ling Yu Hwai Chyuan Ong Saifuddin Nomanbhay Swee Su Lim Institute of Sustainable Energy(ISE) Universiti Tenaga Nasional(UNITEN)Putrajaya CampusJalan Ikram-Uniten43000 KajangSelangorMalaysia Department of Physics Faculty of ScienceKaduna State UniversityTafawa Balewa WayPMB 2339Kaduna 800283Nigeria Department of Engineering School of Engineering and TechnologySunway UniversityJalan UniversitiBandar Sunway47500 Petaling JayaSelangorMalaysia Fuel Cell Institute Universiti Kebangsaan Malaysia43600 UKM BangiSelangorMalaysia

With the projected global surge in hydrogen demand, driven by increasing applications and the imperative for low-emission hydrogen, the integration of machine learning(ML) across the hydrogen energy value chain is a compelling avenue. This review uniquely focuses on harnessing the synergy between ML and computational modeling(CM) or optimization tools, as well as integrating multiple ML techniques with CM, for the synthesis of diverse hydrogen evolution reaction(HER) catalysts and various hydrogen production processes(HPPs). Furthermore, this review addresses a notable gap in the literature by offering insights, analyzing challenges, and identifying research prospects and opportunities for sustainable hydrogen production. While the literature reflects a promising landscape for ML applications in hydrogen energy domains, transitioning AI-based algorithms from controlled environments to real-world applications poses significant challenges. Hence, this comprehensive review delves into the technical,practical, and ethical considerations associated with the application of ML in HER catalyst development and HPP optimization. Overall, this review provides guidance for unlocking the transformative potential of ML in enhancing prediction efficiency and sustainability in the hydrogen production sector.

关键词： Machine learning Computational modeling HER catalyst synthesis Hydrogen energy Hydrogen production processes Algorithm development

Purkait’s triangle revisited:role in sex and ancestry estimation

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Forensic Sciences Research 2022年第3期7卷 440-455页

作者： MennattAllah hassan Attia mohamed hassan Attia Yasmin Tarek Farghaly Bassam Ahmed El-Sayed Abulnoor Sotiris K.Manolis Ruma Purkait Douglas H.Ubelaker Forensic Medicine&Clinical Toxicology Department Faculty of MedicineAlexandria UniversityAlexandriaEgypt Institute for Intelligent Systems Research and Innovation Deakin UniversityVictoriaAustralia Biomedical Engineering Medical Research InstituteAlexandria UniversityAlexandriaEgypt Diagnostic Radiology Faculty of MedicineAlexandria UniversityAlexandriaEgypt Fixed Prosthodontics Faculty of DentistryFayoum UniversityFaiyumEgypt Animal&Human Physiology Faculty of BiologyNational&Kapodistrian University of AthensAthensGreece Department of Anthropology University of AllahabadAllahabadIndia Department of Anthropology Smithsonian InstitutionWashingtonDCUS

Identification of unknown remains recovered from marine and terrestrial locations is a significant humanitarian *** investigation proposes a simple method applicable to fragmentary femora for a more refined level of ancestry and/or sex *** that end,we re-examined Purkait’s triangle which involves three inter-landmark distances between the traction epiphyses and the articular rim of femoral head.A large sample(n=584)from geographically diverse(Egyptian,Indian and Greek)populations was ***,shape(n=3)and trigonometrically derived variables and ratios(n=9 variables)were employed to detect any geographically-clustered morphological differences between these *** forest modelling(RFM)and linear discriminant function analysis(LDA)were employed to create classification models in instances where sex was known or *** sample was apportioned into training and test sets with a ratio 70/*** classification accuracies were evaluated by means of k fold cross-validation *** sex estimation,RFM showed similar performance to ***,RFM outperformed LDA in ancestry *** estimation was satisfactory in the Indian and Egyptian samples albeit the Greek sample was *** Greek samples presented greater morphological overlap with the Indian sample due to high within-group *** samples were accurately assigned to their ancestral category when sex was ***,higher classification accuracies in the validation sample were obtained in the sex-specific model of females than in *** RFM and the linear variables,the overall accuracy reached 83%which is distributed as 95%,71%and 86%for the Egyptian,Indian and Greek females,respectively;whereas in males,the overall accuracy is 72%and is distributed as 58%,87%and 50%for the Egyptian,Indian and Greek males,*** accuracies were also calculated per group in the test data using the 12 derived *** the f

关键词： Forensic sciences forensic anthropology Purkait’s triangle fragmentary femora ancestry estimation random forest modelling international forensic investigations

Hepatitis C virus-related hepatocellular carcinoma:An insight into molecular mechanisms and therapeutic strategies

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World Journal of Hepatology 2012年第12期4卷 342-355页

作者： Denis Selimovic Abdelouahid El-Khattouti Hanan Ghozlan Youssef Haikel Ola Abdelkader mohamed hassan Institut National de la Santé et de la Recherche Médicale U 97767000 StrasbourgFrance Department of Operative Dentistry and Endodontics Dental FacultyUniversity of Strasbourg67000 StrasbourgFrance Cancer Institute University of Mississippi Medical CenterJacksonMS 39216United States Deparment of Microbiology Faculty of ScienceUniversity of AlexandriaAlexandria 4285455Egypt Department of Microbiology Medical Research InstituteUniversity of AlexandriaAlexandria 4285455Egypt

Hepatitis C virus(HCV) infects more than 170 million people worldwide,and thereby becomes a series global health *** infection with HCV is considered one of the major causes of end-stage liver disease including cirrhosis and hepatocellular *** the multiple functions of the HCV proteins and their impacts on the modulation of the intracellular signaling transduction processes,the drive of carcinogenesis during the infection with HCV,is thought to result from the interactions of viral proteins with host cell ***,the induction of mutator phenotype,in liver,by the expression of HCV proteins provides a key mechanism for the development of HCV-associated hepatocellular carcinoma(HCC).HCC is considered one of the most common malignancies worldwide with increasing incidence during the past *** many countries,the trend of HCC is attributed to several liver diseases including HCV ***,the development of HCC is very complicated and results mainly from the imbalance between tumor suppressor genes and oncogenes,as well as from the alteration of cellular factors leading to a genomic *** the poor prognosis of HCC patients,this type of tumor is quite resistance to the available ***,understanding the molecular mechanisms,which are implicated in the development of HCC during the course of HCV infection,may help to design a general therapeutic protocol for the treatment and/or the prevention of this *** review summarizes the current knowledge of the molecular mechanisms,which are involved in the development of HCV-associated HCC and the possible therapeutic strategies.

关键词： Hepatitis C virus Hepatocellular carcinoma Cirrhosis Fibrosis Inflammation Carcinogenesis

Sex Predictive Value of Frontal Sinus Index Compared to Maxillary Sinus Index:Lateral Cephalometric Study

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Journal of Forensic Science and Medicine 2023年第2期9卷 162-166页

作者： Fatma mohamed hassan Maged Nabil Hussein Noran Ayman Abdel Motagally Walaa Samir Department of Forensic Medicine and Clinical Toxicology Faculty of MedicineCairo UniversityCairoEgypt Department of Forensic Evidence Abu Dhabi Police GHQAbu DhabiUnited Arab of Emirates Department of Orthodontics Misr University for Science and TechnologyGizaEgypt Department of Oral and Maxillofacial Radiology Faculty of DentistryBeni-Suef UniversityBeni-SuefEgypt

Sex estimation is a crucial step to outline the biological profile of unknown human *** frontal and maxillary sinuses have unique anatomical features and can be utilized efficiently in individual *** studies investigated the frontal and maxillary sinus indexes separately for sex ***,comparing the predictive value of the frontal sinus index(FSI)to the maxillary sinus index(MSI)has not been investigated *** study aimed to evaluate the sex predicting value of FSI compared to MSI assessed on digital lateral *** retrospective cross-sectional study included 88 digital lateral cephalometric images of known sex(44 males and 44 females)and age(20-50 years).Two radiologists measured the maximum anteroposterior sinus width and height of the frontal sinus and maxillary ***,the sinus index was calculated for each *** obtained frontal and maxillary sinuses parameters were tabulated,along with the patient’s sex and age,and subjected to statistical *** results revealed significant differences between males and females regarding frontal sinus width,FSI,and *** discriminant function analysis obtained in this study accurately predicted sex with an overall accuracy of 71.6%(81.8%of males and 61.4%of females)using FSI,and 60.2%(63.6%in females and 56.8%in males)using *** and maxillary sinus indexes can be useful tools for sex *** function equations were developed for both the frontal and maxillary sinus indexes with higher accuracy rates for FSI compared to MSI.

关键词： Cephalometry discriminant analysis paranasal sinuses sex prediction sinus index

Effect of alternative antibiotics in treatment of cefotaxime resistant spontaneous bacterial peritonitis

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World Journal of Gastroenterology 2013年第8期19卷 1271-1277页

作者： Ahmed Abouelkhair Badawy Tarik Ibrahim Zaher Samar Mahmoud Sharaf mohamed hassan Emara Noha Elsaid Shaheen Talaat Fathy Aly Department of Tropical Medicine Zagazig University Faculty of MedicineZagazig 44519Egypt Department of Clinical Pathology Zagazig University Faculty of MedicineZagazig 44519Egypt

AIM:To evaluate effective alternative antibiotics in treatment of cefotaxime-resistant spontaneous bacterial ***:One hundred cirrhotic patients with spontaneous bacterial peritonitis [ascitic fluid polymorphonuclear cell count(PMNLs) ≥ 250 cells/mm 3 at admission] were empirically treated with cefotaxime sodium 2 g/12 h and volume expansion by intravenous human *** patients were subjected to history taking,complete examination,laboratory tests(including a complete blood cell count,prothrombin time,biochemical tests of liver and kidney function,and fresh urine sediment),chest X-ray,a diagnostic abdominal paracentesis,and the sample subjected to total and differential cell count,chemical examination,aerobic and anaerobic *** were divided after 2 d by a second ascitic PMNL count into group Ⅰ;patients sensitive to cefotaxime(n = 81),group Ⅱ(n = 19);cases resistant to cefotaxime(less than 25% decrease in ascitic PMNL count).Patients of group Ⅱ were randomly assigned into meropenem(n = 11) or levofloxacin(n = 8) *** patients performed an end of treatment ascitic PMNL *** were considered improved when:PMNLs decreased to < 250 cells/mm 3,no growth in previously positive culture cases,and improved clinical manifestations with at least 5 d of antibiotic ***:Age,sex,and Child classes showed no significant difference between group Ⅰ and group Ⅱ.Fever and abdominal pain were the most frequent manifestations and were reported in 82.7% and 80.2% of patients in group Ⅰ and in 94.7% and 84.2% of patients in group Ⅱ,*** in group Ⅱ had a more severe ascitic inflammatory response than group Ⅰ and this was demonstrated by more ascitic lactate dehydrogenase(LDH) [median:540 IU/L(range:150-1200 IU/L) vs median:240 IU/L(range:180-500 IU/L),P = 0.000] and PMNL [median:15 000 cell/mm 3(range:957-23 822 cell/mm 3) vs 3400 cell/mm 3(range:695-26 400 cell/mm 3),P = 0.000] *** fluid culture was po

关键词： Spontaneous bacterial peritonitis Cefotaxime Ascitic polymorphonuclear count Cirrhosis Meropenem Levofloxacin

Identification of functional tumor necrosis factor-alpha promoter variants associated with Helicobacter pylori infection in the Sudanese population: Computational approach

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World Journal of Gastroenterology 2022年第2期28卷 242-262页

作者： Abeer Babiker Idris Alaa B Idris Manal A Gumaa Mohammed Babiker Idris Amanda Elgoraish mohamed Mansour Dalia Allam Bashir MO Arbab Nazar Beirag El-Amin M Ibrahim mohamed a hassan Department of Agricultural Science and Technology Institute of Natural and Applied SciencesErciyes UniversityKayseri 38039Turkey Department of Medical Microbiology Faculty of Medical Laboratory SciencesUniversity of KhartoumKhartoum 11111Sudan Department of Neurosurgery Ribat University HospitalKhartoum 11111Sudan BioMérieux Clinical and Application Advisor Al-Jeel Medical Co.Riyadh 11422Saudi Arabia Department of Epidemiology Tropical Medicine Research InstituteKhartoum 11111Sudan Department of Gastroenterology Ibn Sina Specialized HospitalKhartoum 11111Sudan Department of Gastroenterology Modern Medical CentreKhartoum 11111Sudan Biosciences College of HealthMedicine and Life SciencesBrunel UniversityLondon UB83PHUxbridgeUnited Kingdom Department of Translation Bioinformatics Detavax BiotechKayseri 38350Turkey

BACKGROUND Helicobacter pylori(***)is a ubiquitous bacterium that affects nearly half of the world’s population with a high morbidity and mortality *** within the tumor necrosis factor-alpha(TNF-A)promoter region are considered a possible genetic basis for this *** To functionally characterize the genetic variations in the TNF-A 5’-region(-584 to+107)of Sudanese patients infected with *** using in silico *** An observational study was carried out in major public and private hospitals in Khartoum state.A total of 122 gastric biopsies were taken from patients who had been referred for *** DNA was *** of the TNF-A-1030 polymorphism was performed using PCR with confronting two-pair primer to investigate its association with the susceptibility to *** infection in the Sudanese ***,Sanger sequencing was applied to detect single nucleotide polymorphisms in the 5’-region(-584 to+107)of TNF-A in ***-infected *** analyses were used to predict whether these mutations would alter transcription factor binding sites or composite regulatory elements in this region.A comparative profiling analysis was conducted in 11 species using the ECR browser and multiple-sequence local alignment and visualization search engine to investigate the possible ***,a multivariate logistic regression model was constructed to estimate odds ratios and their 95%confidence intervals for the association between TNF-A-1030,sociodemographic characteristics and *** *** were statistically significant if PA,-76)was located at the in silico-predicted promoter region(-146 to+10),and it was predicted to alter transcription factor b

关键词： 5’-region Promoter TNF-A Helicobacter pylori In silico analysis Sudan

Effects of methanolic extract of <i>Pausinystalia yohimbe</i>bark on blood glucose level in normal fasting rats

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Health 2012年第12期4卷 1225-1228页

作者： Hozeifa mohamed hassan Taj Eldin Imad mohamed Elhadi mohamed mohamed Ahmed Abd Elwahab hassan mohamed Nizar Sirag Department of Pharmacognosy Faculty of Pharmacy University of Gezira Wad Medani Sudan Department of Pharmacology and Toxicology Medicinal and Aromatic Plant Research Institute National Centre of Research Khartoum Sudan Department of Pharmacology Faculty of Pharmacy University of Gezira Wad Medani Sudan

Background: Pausinystalia yohimbe (L.) is a member of the family Rubiaceae. It is a valuable medicinal tree, distributed in evergreen closed-canopy forests in West Africa. It is traditionally used for treatment of erectile dysfunction and diabetes. Objective: This was an attempt to evaluate the effects of methanolic extract of P. yohimbe bark on blood glucose level in normal fasting rats. Methods: Different doses of methanolic extract of P. yohimbe bark (5, 10, 20, 40 and 80 mg/kg/mL) were orally administered to normal fasting rats to assess their effects on blood glucose levels. Results: The methanolic extract of P. yohimbe bark in different concentrations (5, 10, 20, 40 and 80 mg/kg/mL) when administered to normal fasting rats, only a considerable reduction (26.57 mg/dL) was produced by the dose of 20 mg/kg/mL. Conclusion and Recommendation: Although P. yohimbe has long been reported to regulate blood glucose levels;such effect is unclear and remains requiring further studies.

关键词： Pausinystalia yohimbe Bark Yohimbine Fasting Blood Glucose Level Hypoglycemia

Effects of methanolic extract of yohimbe bark (<i>Pausinystalia yohimbe</i>) on isolated rabbit aortic strip and rat uterus

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Health 2013年第6期5卷 1016-1020页

作者： Hozeifa mohamed hassan Imad mohamed Taj Eldin Elhadi mohamed Ahmed Abd Elwahab hassan mohamed Nizar Sirag Department of Pharmacognosy Faculty of Pharmacy University of Gezira Wad Medani Sudan Department of Pharmacology and Toxicology Medicinal and Aromatic Plant Research Institute National Centre of Research Khartoum Sudan Department of Pharmacology Faculty of Pharmacy University of Gezira Wad Medani Sudan

Background: Medicinal plants contain physiologically active principles that over the years have been exploited in traditional medicine for the treatment of various ailments. Objectives and Methods: This study aimed to investigate the effects of the methanolic extract of Pausinystalia yohimbe bark (5 mg/ml) on isolated rabbit aortic strip and rat uterus. Results: methanolic extract of P. yohimbe bark (5 mg/ml) produced relaxation of the phenylephrine precontracted-rabbit aortic strip. This relaxation may be resulted through nitric oxide (NO), since the pretreatment of the isolated rabbit aortic strip with methylene blue inhibited the NO-mediated relaxation. Moreover, the extract exhibited relaxation of rat uterine muscles, which appeared to be not mediated by activation of β2-adrenoceptors and/or H2 receptors, since the relaxant effect continued even after the pretreatment of the tissue with propranolol and ranitidine respectively. Conclusion: The obtained results revealed that methanolic extract of P. yohimbe bark caused relaxation of both isolated rat uterus and rabbit aortic strip through facilitating the role of endogenous compounds such as NO.

关键词： P. yohimbe Bark Isolated Tissues Aortic Strip Rat Uterus Relaxation Nitric Oxide

Integrated Nutrient Management Improves Productivity and Quality of Sugarcane(Saccharum Officinarum L.)

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Phyton-International Journal of Experimental Botany 2022年第2期91卷 439-469页

作者： Md.Shamsul Arefin Md.Ariful Islam Md.Mokhlesur Rahman Md.Abdul Alim Sabry hassan Mahmoud F.K.Soliman mohamed M.hassan Rajan Bhatt Akbar Hossain Physiology and Sugar Chemistry Division Bangladesh Sugarcrop Research InstituteIshurdi6620Bangladesh On-Farm Research Division Bangladesh Agricultural Research InstitutePabna6600Bangladesh Department of Agricultural Chemistry Bangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Food Technology and Rural Industries Bangladesh Agricultural UniversityMymensingh2202Bangladesh Department of Biology College of ScienceTaif UniversityTaif21944Saudi Arabia Nature Conservation Sector Egyptian Environmental Affairs AgencyCairo11728Egypt Regional Research Station Panjab Agricultural UniversityKapurthala144601India Bangladesh Wheat and Maize Research Institute Dinajpur5200Bangladesh

Sugarcane is one of the major important sugar yielding crops in *** an exhaustive crop,sugarcane removes a huge amount of plant nutrients from the ***,the combined use of organic and inorganic fertilizers can be a good approach to deal with nutrient depletion and promote sustainable crop production as well as improve soil ***,an attempt was made to identify the most fruitful and profitable integrated nutrient management on the aspects of growth,yield and quality of sugarcane in two consecutive growing *** treatments:T_(1)=Control,T_(2)=165:55:120:30:10:2.5:4 kg N:P:K:S:Mg:Zn:B ha^(−1),T_(3)=Poultry Litter(PL)at 5 t ha^(−1)+95:51:87:9:10:2.5:4 kg N:P:K:S:Mg:Zn:B ha^(−1),T_(4)=Cow Dung(CD)at 15 t ha^(−1)+36:52:60:17:10:2.5:4 kg N:P:K:S:Mg:Zn:B ha^(−1),T_(5)=Press Mud(PM)at 15 t ha^(−1)+10:50:43:0:10:2.5:4 kg N:P:K:S:Mg:Zn:B ha^(−1),T_(6)=Mustard Oil Cake(MOC)at 0.5 t ha^(−1)+140:54:115:25:10:2.5:4 kg N:P:K:S:Mg:Zn:B ha^(−1)and T_(7)=GM(Green Manure)at 5 t ha^(−1)+140:53:100:28:10:2.5:4 kg N:P:K:S:Mg:Zn:B ha^(−1)were used in this *** years data showed that treatment T_(3)produced the maximum amount of tillers,total dry matter yield,millable sugarcane,cane yield and sugar yield,followed by the T_(4)*** highest stalk heights were recorded in the T_(3)treatment,which was statistically similar to all other treatments except T_(1)and T_(2).The juice quality parameters viz.,brix and pol in cane were found significant in treatment T_(3)while the highest purity was obtained in the T_(7)*** the data of Jaggery(goor)quality parameters,the highest sucrose content,color transmittance,Jaggery(goor)recovery and the lowest ash content of Jaggery(goor)were observed in the T_(3)treatment,which was statistically similar to the T_(4)treatment in both *** highest cost of production was obtained from the T_(6)treatment while the highest gross return,net return and BCR were recorded in the T_(3)*** sig

关键词： Nutrient fertilizer growth physiology yield quality sugarcane