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Association between Serum Glutathione Peroxidases and Superoxide Dismutases mRNA Level with Coronary Artery Disease

Health 2017年第2期9卷 252-260页

作者： Ali reza Abaspour Mohammad Taghikhani mohamad reza parizade Mohsen Moohebati Fahime Ghafoori Mehraneh Mehramiz Maryam Tayefi Amir Avan Marzeye Ghalandari Gordon A. A. Ferns Majid Ghayour-Mobarhan Department of Molecular Science Faculty of Medicine North Khorasan University of Medical Science Bojnurd Iran Department of Clinical Biochemistry Tarbiat Modares University Tehran Iran Department of Biochemistry and Nutrition Faculty of Medicine Mashhad University of Medical Science (MUMS) Mashhad Iran Cardiovascular Research Center Avicenna Research Institute Mashhad University of Medical Science (MUMS) Mashhad Iran Department of Modern Sciences and Technologies School of Medicine Mashhad University of Medical Sciences Mashhad Iran Department of Biochemistry Faculty of Basic Science Payame Noor University Mashhad Iran Division of Medical Education Brighton & Sussex Medical School Brighton UK

Background: Oxidative stress plays a crucial role in the pathogenesis and progression of many diseases, including cardiovascular disease (CVD) and diabetes mellitus. Oxidative stress results from an imbalance between free radical formation and the protective antioxidant mechanisms. The latter mechanisms include superoxide dismutases (SODs) and glutathione peroxidases (GPx) that scavenge excessive ROS and protect cells against excess ROS production. The aim of current study was to determine the serum levels of SOD and serum GPx mRNA as well as the serum prooxidant-antioxidant balance in CVD patients. Method: A total of 103 subjects were recruited, with ≥50% stenosis (Angio+) or –). The expression levels of SOD and GPx in serum were measured using real time PCR. Biochemical-analyses (e.g., triglycerides;high-density lipo-protein cholesterol;low-density lipoprotein cholesterol;fasting-blood-glucose) were determined in all the subjects. Associations of SOD and GPx levels with biochemical and anthropometric characteristics were assessed together with evaluation of the serum pro-oxidant-antioxidant balance (PAB). Results: CVD subjects had a significantly higher level of fasting blood glucose (FBG), TC, LDL-C, TG and hs-CRP levels, as compared to control subjects. The level of serum PAB was significantly higher in the CVD group, 117.92 ± 35.51 and 110.65 ± 27.65 μg/dl in the angio– and angio+ groups, respectively compared to the control group (54.26 + 23.25). Additionally we observed that the SOD-3 level was higher in angio+ group versus control subjects. Conclusion: We have found that patients with CVD had a significantly higher prooxidant-antioxidant and SOD-3 levels. Further studies in larger multi-center setting are warranted to explore the value of emerging biomarker in CVD patients.

关键词： Coronary Artery Disease Glutathione Peroxidases Superoxide Dismutases Real Time PCR Angiography

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Strength Performance and Microstructure Characteristic of Naturally-Bonded Fiberboard Composite from Malaysian Bamboo(Bambusa vulgaris)

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Journal of Renewable Materials 2022年第10期10卷 2581-2591页

作者： Shahril Anuar Bahari Mohd Nazarudin Zakaria Syaiful Osman Falah Abu mohamad Jani Saad reza Hosseinpourpia Eco-Technology Program Faculty of Applied SciencesUniversiti Teknologi MARA(UiTM)Shah Alam40450Malaysia Engineering Research Centre Malaysian Agricultural Research and Development Institute(MARDI)Serdang43400Malaysia Department of Forestry and Wood Technology Linnaeus UniversityVäxjö35195Sweden

This study investigated the mechanical properties and microstructural characteristics of fiberboard composite produced by naturally-bonded Malaysian bamboo fiber(Bambusa vulgaris).The components that obtained through soda pulping of bamboo culms such as fiber and black liquor,were used for the preparation of high-density fibreboard composite at two target densities of 850 and 950 kg/m^(3).The bamboo fiberboard composite(BFC)were then produced at 200°C and two pressing parameters of 125 and 175 s/mm.The mechanical properties,e.g.,flexural strength and internal bonding(IB)of BFC samples were evaluated according to BS EN 310:1993 and BS EN 319:1993,respectively.It was found that the mechanical performance of the composite with 850 kg/m^(3)density was significantly higher than 950 kg/m^(3)ones,especially for the samples with 125 s/mm pressing parameter.Microstructure characteristic of the BFC samples illustrated that the fiber linkages were cracked in the composites with higher density,e.g.,the composite with the density of 950 kg/m^(3)and also black liquor were slightly degraded at longer pressing time,which led to the reduction in mechanical properties,especially in IB strength.

关键词： Bamboo fiber naturally-bonded black liquor mechanical properties SEM composite

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A novel and selective oxidation of benzylic alcohols with polymer-supported periodic acid under mild aprotic conditions

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Chinese Chemical Letters 2012年第1期23卷 21-24页

作者： Ali reza Pourali Mehrosadat Tabaean S.mohamad reza Nazifi School of Chemistry Damghan UniversityDamghan 36715/364Iran

新聚合氧化试剂被支持周期的酸在上准备 poly (1,4-phenylene-2,5-pyridine dicarboxyamide ) 。这聚合试剂以倒流条件在 CH3CN 被用于主要 benzylic 白酒的选择氧化到相应 benzaldehydes。优秀选择在氧化反应象 non-benzylic 白酒一样... 详细信息

新聚合氧化试剂被支持周期的酸在上准备 poly (1,4-phenylene-2,5-pyridine dicarboxyamide ) 。这聚合试剂以倒流条件在 CH3CN 被用于主要 benzylic 白酒的选择氧化到相应 benzaldehydes。优秀选择在氧化反应象 non-benzylic 白酒一样在主要本甲基白酒和第二等的之间被观察。Allylic 白酒也与好收益被变换成相应的醛。

关键词：聚合物试剂选择性氧化苄醇质子条件苯甲醛非选择性氧化反应烯丙醇

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Improvement of the microstructural features and mechanical properties of advanced high-strength steel DP590 welds

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International Journal of Minerals,Metallurgy and Materials 2021年第6期28卷 1022-1029页

作者： Arian Ghandi Morteza Shamanian mohamad reza Salmani Jalal Kangazian College of Pardis Materials Engineering SectionIsfahan University of TechnologyIsfahan 84156-83111Iran Department of Materials Engineering Isfahan University of TechnologyIsfahan 84156-83111Iran Engineering&Quality of Auto Steel Division SAIPA GroupTehranIran

The effects of the welding current mode in resistance spot welding on the microstructure and mechanical properties of advanced high-strength steel dual-phase 590(DP590)sheets were investigated.Results showed that a rough martensitic structure was formed in the weld zone of the sample welded via the single-pulsed mode,whereas the microstructure in the heat-affected zone consisted of a very rough martensitic microstructure and rough ferrite.However,using the secondary pulse mode led to the formation of tempered martensite in the weld zone.The maximum load and the energy absorption to failure of the samples with the secondary pulsed cycle were higher than those of the samples with the single-pulsed mode.Tensile shear results indicated that the secondary pulsed mode could significantly change the mode of failure upon shear tension testing.Therefore,the obtained results suggest that the use of secondary pulsed mode can improve the microstructural feature and mechanical properties of advanced high-strength steel DP590 welds.

关键词： advanced high-strength steel resistance spot welding microstructure mechanical properties

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Interpretation of Water Samples by Correspondence Analysis for Radioactive Elements in the Northern Coast of Oman Sea

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Journal of Metallic Material Research 2022年第1期5卷 25-31页

作者： Farshad Darabi-Golestan mohamad reza Zare Department of Mining and Metallurgical Engineering Amirkabir University of TechnologyTehranIran Department of Physics Faculty of SciencesUniversity of IsfahanIsfahan81746-73441Iran

Oman Sea is connecting belt between the Indian Ocean and Persian Gulf.Because it strategic and environmental aim,presence of natural radionuclide ^(226)Ra,^(232)Th,^(40)K and ^(137)Cs as man-made element is considered.Water samples were taken from 36 marine spots at the coastal strip from Hormoz canyon to Goatr seaport in the northern coast of Oman Sea.Correspondence analysis is used to identify variation and relationship between samples(Q-mood analysis)and variable(R-mood analysis)based on approximate χ^(2)distances.Radioactive elements(^(226)Ra,^(232)Th and^( 40)K),physical(temperature,pH,turbidity,conductivity,special density)and chemical(salinity,oxygen and chlorophyll)parameters of water for 36 samples handled by correspondence analysis,there are two outstanding result,(1)Radioactive elements show high correlation in factors by greater eigenvalue,and (2)some of the samples such as W13,W24 and rather W02,W05 and W12 show highest activity from Radioactive elements and also temperature and conductivity show nearest relation with them in many factors.

关键词： Hormoz canyon R-mood analysis Correspondence analysis Radioactive elements Marine spot samples

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Thermodynamic and Adsorption Behaviour of Medicinal Nitramine as a Corrosion Inhibitor for AISI Steel Alloy in HCl Solution

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Journal of Materials Science & Technology 2013年第9期29卷 884-892页

作者： Ali reza Hosein Zadeh Iman Danaee mohamad Hosein Maddahy Abadan Faculty of Petroleum Engineering Petroleum University of Technology

The inhibition ability of 2-amino-5-nitrothiazole （Nitramine） against the corrosion of AISI steel 4130 in 1 mol/L HCI solution was evaluated by polarization, electrochemical impedance spectroscopy （EIS） and chronoamperometry. Polarization studies indicated that nitramine retards both the cathodic and anodic reactions through chemical adsorption and blocks the active corrosion sites. The adsorption of this compound obeyed the Temkin＇s adsorption isotherm. The inhibition efficiency was increased with inhibitor concentration as well as temperature. EIS data were analysed by equivalent circuit model shows that as the inhibitor concentration increased the charge transfer resistance of steel increased whilst double layer capacitance decreased. Kinetic and thermodynamic parameters such as activation energy, enthalpy, entropy and free energy of activation and adsorption were calculated. Atomic force microscopy and optical microscopy were used to study the steel surface with and without inhibitor.

关键词： Steel 4130 Corrosion Inhibitor Adsorption isotherm Temkin

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A hybrid LQR-PID control design for seismic control of buildings equipped with ATMD

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Frontiers of Structural and Civil Engineering 2018年第1期12卷 44-57页

作者： Amir Hossein HEIDARI Sadegh ETEDALI mohamad reza JAVAHERI-TAFTI Department of Civil Engineering Taft Branch Islamic Azad University Taft Iran Department of Civil Engineering Birjand University of Technology P.O. Box 97175-569 Birjand Iran

This paper presents an efficient hybrid control approach through combining the idea of proportional- integral-derivative （PID） controller and linear quadratic regulator （LQR） control algorithm. The proposed LQR-PID controller, while having the advantage of the classical PID controller, is easy to implement in seismic-excited structures. Using an optimization procedure based on a cuckoo search （CS） algorithm, the LQR-PID controller is designed for a seismic- excited structure equipped with an active tuned mass damper （ATMD）. Considering four earthquakes, the performance of the proposed LQR-PID controller is evaluated. Then, the results are compared with those given by a LQR controller. The simulation results indicate that the LQR-PID performs better than the LQR controller in reduction of seismic responses of the structure in the terms of displacement and acceleration of stories of the structure.

关键词： eismic control tuned mass dampers cuckoo search PID controller LQR controller

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Bayesian adjustment of gastric cancer mortality rate in the presence of misclassification

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World Journal of Gastrointestinal Oncology 2017年第4期9卷 160-165页

作者： Nastaran Hajizadeh mohamad Amin Pourhoseingholi Ahmad reza Baghestani Alireza Abadi Mohammad reza Zali Department of Biostatistics Shahid Beheshti University of Medical Sciences Basic and Molecular Epide-miology of Gastrointestinal Disorders Research Center Research Institute for Gastroenterology and Liver DiseasesShahid Beheshti University of Medical Sciences Gastroenterology and Liver Diseases Research Center Research Institute for Gastroenterology and Liver DiseasesShahid Beheshti University of Medical Sciences

AIM To correct for misclassification error in registering causes of death in Iran death registry using Bayesian method.METHODS National death statistic from 2006 to 2010 for gastric cancer which reported annually by the Ministry of Health and Medical Education included in this study. To correct the rate of gastric cancer mortality with reassigning the deaths due to gastric cancer that registered as cancer without detail, a Bayesian method was implemented with Poisson count regression and beta prior for misclassified parameter, assuming 20% misclassification in registering causes of death in Iran.RESULTS Registered mortality due to gastric cancer from 2006 to 2010 was considered in this study. According to the Bayesian re-estimate, about 3%-7% of deaths due to gastric cancer have registered as cancer without mentioning details. It makes an undercount of gastric cancer mortality in Iranian population. The number and age standardized rate of gastric cancer death is estimated to be 5805(10.17 per 100000 populations), 5862(10.51 per 100000 populations), 5731(10.23 per 100000 populations), 5946(10.44 per 100000 populations), and 6002(10.35 per 100000 populations), respectively for years 2006 to 2010.CONCLUSION There is an undercount in gastric cancer mortality in Iranian registered data that researchers and authorities should notice that in sequential estimations and policy making.

关键词：错误分类贝叶斯的方法死亡的原因胃的癌症伊朗

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Bayesian adjustment for over-estimation and under-estimation of gastric cancer incidence across Iranian provinces

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World Journal of Gastrointestinal Oncology 2017年第2期9卷 87-93页

作者： Nastaran Hajizadeh mohamad Amin Pourhoseingholi Ahmad reza Baghestani Alireza Abadi Mohammad reza Zali Department of Biostatistics Shahid Beheshti University of Medical Sciences Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center Research Institute for Gastroenterology and Liver Diseases Shahid Beheshti University of Medical Sciences Gastroenterology and Liver Diseases Research Center Research Institute for Gastroenterology and Liver Diseases Shahid Beheshti University of Medical Sciences

AIM To correct the misclassification in registered gastric cancer incidence across Iranian provinces in cancer registry data. METHODS Gastric cancer data is extracted from Iranian annual of national cancer registration report 2008. A Bayesian method with beta prior is implemented to estimate the rate of misclassification in registering patient'spermanent residence in neighboring province. Each time two neighboring provinces with lower and higher than 100% expected coverage of cancer cases are selected to be entered in the model. The expected coverage of cancerous patient is reported by medical university of each province. It is assumed that some cancer cases from a province with a lower than 100% expected coverage are registered in their neighboring province with more than 100% expected coverage. RESULTS The condition was true for 21 provinces from a total of 30 provinces of Iran. It was estimated that 43% of gastric cancer cases of North and South Khorasan provinces in north-east of Iran was registered in Razavi Khorasan as the neighboring facilitate province; also 72% misclassification was estimated between Sistan and balochestan province and Razavi Khorasan. The misclassification rate was estimated to be 36% between West Azerbaijan province and East Azerbaijan province, 21% between Ardebil province and East Azerbaijan, 63% between Hormozgan province and Fars province, 8% between Chaharmahal and bakhtyari province and Isfahan province, 8% between Kogiloye and boyerahmad province and Isfahan, 43% Golestan province and Mazandaran province, 54% between Bushehr province and Khozestan province, 26% between Ilam province and Khuzestan province, 32% between Qazvin province and Tehran province(capital of Iran), 43% between Markazi province and Tehran, and 37% between Qom province and Tehran. CONCLUSION Policy makers should consider the regional misclassification in the time of programming for cancer control, prevention and resource allocation.

关键词：癌症发生登记错误分类贝叶斯的修正胃的癌症伊朗

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Oncolytic viruses:A novel treatment strategy for breast cancer

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Genes & Diseases 2023年第2期10卷 430-446页

作者： Mohammad Javanbakht Sanaz Tahmasebzadeh Luca Cegolon Nasrin Gholami Mandana Kashaki Hassan Nikoueinejad mohamad Mozafari Mahsa Mozaffari Shi Zhao Mostafa Khafaei Morteza Izadi Saeid Fathi reza Akhavan-Sigari Nephrology and Urology Research Center Baqiyatallah University of Medical SciencesTehran ***Iran Mehrestan Health Network Iranshahr University of Medical SciencesIranshahr ***Iran University of Trieste Department of MedicalSurgical & Health SciencesTrieste 34128Italy University Health Agency Giuliano-Isontina (ASUGI) Public Health DepartmentTriesteItaly Hematology and Oncology Research Center Tabriz University of Medical SciencesTabriz ***Iran Shahid Akbarabadi Clinical Research Development Unit (ShACRDU) Iran University of Medical Sciences (IUMS)Tehran ***Iran Department of General Surgery Urmia University of Medical ScienceUrmia 57147Iran Department of Pediatrics Iran University of Medical SciencesTehran ***Iran JC School of Public Health and Primary Care Chinese University of Hong KongHong Kong Special Administrative Region 999077China Human Genetics Research Center Baqiyatallah University of Medical SciencesTehran 169875931Iran Health Research Center Baqiyatallah University of Medical SciencesTehran ***Iran Razi Vaccine and Serum Research Institute Agriculture ResearchEducation and Extension Organization (AREEO)Karaj 11365-1558Iran Department of Neurosurgery University Medical CenterTuebingen 72076Germany

Breast cancer,an unceasingly occurring neoplasm,is one of the major determinants of mortality in women.Several ineffective attempts have been pursued using with conventional therapies against breast cancer.Resistance to existing therapies and their respective debilitating adverse effects have led research toward a new era of cancer treatment using viruses.Virotherapy constitutes a developing treatment modality with multiple mechanisms of therapeutic activity in which the viruses can be directly oncolyticand can express transgenes or induce host immune response against tumor cells.Several different DNA-and RNA-containing viruses have been considered for virotherapy of breast cancer including adenovirus,herpes virus,vaccinia,reovirus,Newcastle Disease virus,measles virus and vesicular stomatitis virus.This review aims to summarize the viro-therapeutical agents against breast malignancies.Key Scientific Concepts of Review:In this review paper,we proposed a new strategy to virus's combinatorial treatments using several kinds of transgenes and drugs.These recombinant viruses have provided evidence of treatment efficacy against human breast cancer.

关键词： Adenovirus Breast cancer Herpes virus Measles virus Newcastle disease virus Reovirus Vaccinia Vesicular stomatitis virus Virotherapy

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