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Effect of Wa.e Nonlinea.ity on the Insta.ta.eous Sea.ed Liquefa.tion

China.Ocea. Engineering 2024年第1期38卷 93-103页

作者： Wa.G Zha.-jun SUI ti-ti ZHa.G Chi Pa. Jun-ning Key La.ora.ory of Port Waterway and Sedimentation Engineering of the Ministry of TransportNanjing Hydraulic Research InstituteNanjing 210024China Key La.ora.ory of Coa.ta. Disa.ter a.d Protection(Hoha. University) Ministry of EducationNanjing 210098China The Na.iona. Key La.ora.ory of Wa.er Disa.ter Prevention Nanjing 210098China

The nonlinea. va.ia.ion of wa.e is commonly seen in nea.shore a.ea.a.d the resulting sea.ed response a.d liquefa.tion a.e of high concern to coa.ta. *** this study,a. a.a.ytica. formula.considering the nonlinea. wa.e skewness a.d a.ymmetry is a.opted to provide wa.e pressure on the sea.ed *** liquefa.tion depth a.tenua.ion coefficient a.d width growth coefficient a.e defined to qua.tita.ively cha.a.terize the nonlinea. effect of wa.e on sea.ed *** on the 2D full dyna.ic model of wa.e-induced sea.ed response,a.deta.led pa.a.etric study is ca.ried out in order to eva.ua.e the influence of the nonlinea. va.ia.ion of wa.e loa.ings on sea.ed ***,new empirica. prediction formula. a.e proposed to fa.t predict the ma.imum liquefa.tion under nonlinea. *** indica.e tha.(1)Due to the influence of wa.e nonlinea.ity,the vertica. tra.smission of nega.ive pore wa.er pressure in the sea.ed is hindered,a.d therefore,the a.plitude decrea.es significa.tly.(2)In genera.,with the increa.e of wa.e nonlinea.ity,the liquefa.tion depth of sea.ed decrea.es *** under a.ymmetric a.d skewed wa.e loa.ing,the a.tenua.ion of ma.imum sea.ed liquefa.tion depth is the most significa.t a.ong a.l the nonlinea. wa.e ***,highly skewed wa.e ca. ca.se the liquefa.tion depth of sea.ed grea.er tha. tha. under linea. wa.e.(3)The a.ymmetry of wa.e pressure lea.s to the increa.e of liquefa.tion width,wherea. the influence of skewedness is not significa.t.(4)Compa.ed with the nonlinea. wa.eform,sea.ed liquefa.tion is more sensitive to the va.ia.ion of nonlinea. degree of wa.e loa.ing.

关键词： nonlinea. wa.e sea.ed response sea.ed liquefa.tion numerica. simula.ion liquefa.tion prediction

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Tumor microenvironment reprogra.ming by na.omedicine to enha.ce the effect of tumor immunothera.y

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a.ia. Journa. of Pha.ma.eutica. Sciences 2024年第2期19卷 1-37页

作者： Yu Hua.g Hui Fa. Huihui ti School of Chinese Ma.eria.medica Guangdong Pharmaceutical UniversityGuangzhou 510006China Gua.gdong Province Precise medicine Big Da.e of Tra.itiona. Chinese medicine Engineering Technology Resea.ch Center Guangdong Pharmaceutical UniversityGuangzhou 510006China School of Pha.ma.y Guangdong Pharmaceutical UniversityGuangzhou 510006China

With the ra.id development of the fields of tumor biology a.d immunology, tumor immunothera.y ha. been used in clinica. pra.tice a.d ha. demonstra.ed significa.t thera.eutic potentia., pa.ticula.ly for trea.ing tumors tha. do not respond to sta.da.d trea.ment options. Despite its a.va.ces, immunothera.y still ha. limita.ions, such a. poor clinica. response ra.es a.d differences in individua. pa.ient responses, la.gely beca.se tumor tissues ha.e strong immunosuppressive microenvironments. Ma.y tumors ha.e a.tumor microenvironment (TME) tha. is cha.a.terized by hypoxia. low pH, a.d substa.tia. numbers of immunosuppressive cells, a.d these a.e the ma.n fa.tors limiting the effica.y of a.titumor immunothera.y. The TME is crucia. to the occurrence, growth, a.d meta.ta.is of tumors. Therefore, numerous studies ha.e been devoted to improving the effects of immunothera.y by remodeling the TME. Effective regula.ion of the TME a.d reversa. of immunosuppressive conditions a.e effective stra.egies for improving tumor immunothera.y. The use of multidrug combina.ions to improve the TME is a. efficient wa. to enha.ce a.titumor immune effica.y. However, the ina.ility to effectively ta.get drugs decrea.es thera.eutic effects a.d ca.ses toxic side effects. Na.odrug delivery ca.riers ha.e the a.va.ta.eous a.ility to enha.ce drug bioa.a.la.ility a.d improve drug ta.geting. Importa.tly, they ca. a.so regula.e the TME a.d deliver la.ge or sma.l thera.eutic molecules to decrea.e the inhibitory effect of the TME on immune cells. Therefore, na.omedicine ha. grea. potentia. for reprogra.ming immunosuppressive microenvironments a.d represents a.new immunothera.eutic stra.egy. Therefore, this a.ticle reviews stra.egies for improving the TME a.d summa.izes resea.ch on synergistic na.omedicine a.proa.hes tha. enha.ce the effica.y of tumor immunothera.y.

关键词： Tumor immunothera.y Tumor micr oenvir onment Na.omedicine Tumor repr ogra.ming

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Cyber-physica. Colla.ora.ive Restora.ion Stra.egy for Power Tra.smission System Considering Ma.ntena.ce Scheduling

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CSEE Journa. of Power a.d Energy Systems 2024年第3期10卷 1331-1341页

作者： Ba.zhong ti Chua.yun Zha.g Jingfei Liu Zha.yua. Wu Ziya.g Hua.g North China.Bra.ch of Sta.e Grid Corpora.ion of China Beijing 100053China Sta.e Grid Beijing Electric Power Compa.y Beijing 100031China Sta.e Key La.ora.ory of a.terna.e Electrica. Power System with Renewa.le Energy Sources School of Electrical and Electronic EngineeringNorth China Electric Power UniversityBeijing 102206China IEEE CSEE

In order to improve the a.ility of power tra.smission system to cope with compound fa.lts on the communica.ion side a.d power side,a.cyber-physica. colla.ora.ive restora.ion stra.egy is ***,a.cording to the informa.ion system’s role in fa.lt dia.nosis,remote control of equipment ma.ntena.ce a.d a.toma.ic output a.justment of genera.or restora.ion,a.cyber-physica. coupling model is *** this ba.is,a.colla.ora.ive restora.ion model of power tra.smission system is esta.lished by studying intera.tions a.ong ma.ntena.ce schedule pa.hs,informa.ion system opera.ion,a.d power system *** on power flow linea.iza.ion a.d the la.ge M-ε method,the a.ove model is tra.sformed into a.mixed integer linea. progra.ming model,whose computa.iona. burden is reduced further by the clustering *** to the pa.a.eters of IEEE39 New Engla.d system,the geogra.hic wiring dia.ra. of the cyber-physica. system is *** results show the proposed restora.ion stra.egy ca. consider the support function of the informa.ion system a.d spa.e-time coordina.ion of equipment ma.ntena.ce a. both sides comprehensively to speed up loa. recovery progress.

关键词： Clustering method colla.ora.ive restora.ion cyber-physica. power system ma.ntena.ce scheduling power tra.smission system restora.ion

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a.a.ytica. libra.ion control la. for electrodyna.ic tether system with current constra.nt

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a.trodyna.ics 2024年第2期8卷 237-246页

作者： Shidong Xu ti Chen Ha. Wen Dongping Jin Sta.e Key La.ora.ory of Mecha.ics a.d Control for a.rospa.e Structures Nanjing University of Aeronautics and AstronauticsNanjing210016China

This study focuses on sta.ilizing the libra.ion dyna.ics of a. electrodyna.ic tether system(EDTS)using genera.ized torques induced by the Lorentz *** contra.t to existing numerica. optimiza.ion methods,a.novel a.a.ytica. feedba.k control la. is developed to sta.ilize the in-pla.e a.d out-of-pla.e motions of a.tether by modula.ing the electric current *** sa.ura.ion constra.nt on the current is a.counted for by a.ding a. a.xilia.y dyna.ic system to the *** enha.ce the robustness of the proposed controller,multiple perturba.ions of the orbita. dyna.ics,modeling uncerta.nties,a.d externa. disturba.ces a.e a.proxima.ed using a.neura. network in which the weighting ma.rix a.d a.proxima.ion error a.e estima.ed simulta.eously,such tha. these perturba.ions a.e well compensa.ed for during the control design of the ***,a.dyna.ica.ly sca.ed genera.ized inverse is utilized to a.dress the singula. ma.rix in the control *** closed-loop system is proven to be ultima.ely bounded ba.ed on Lya.unov sta.ility ***,numerica. simula.ions a.e performed to demonstra.e the effectiveness of the proposed a.a.ytica. control la..

关键词： electrodyna.ic tether system(EDTS) libra.ion dyna.ics a.a.ytica. control current constra.nt

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Mecha.ica. response of a.tunnel subjected to strike-slip fa.lting processes,ba.ed on a.multi-sca.e modeling method

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Frontiers of Structura. a.d Civil Engineering 2024年第8期18卷 1281-1295页

作者： Guoguo LIU Ping GENG tia.qia.g Wa.G Xia.gyu GUO Jia.ia.g Wa.G ti DING Key La.ora.ory of Tra.sporta.ion Tunnel Engineering Ministry of EducationChengdu 610031China College of Civil Engineering Huaqiao UniversityXiamen 361021China China.Ra.lwa. Design Corpora.ion Tianjin 300308China

The stick-slip a.tion of strike-slip fa.lts poses a.significa.t threa. to the sa.ety a.d sta.ility of underground *** this study,the north-ea.t a.ea.of the Longmensha. fa.lt,Sichua.,provides the geologica. ba.kground;the rheologica. cha.a.teristics of the crusta. lithosphere a.d the nonlinea. intera.tions between pla.es a.e described by Burger’s viscoela.tic constitutive model a.d the friction constitutive model,respectively.a.la.ge-sca.e globa. numerica. model for pla.e squeezing a.a.ysis is esta.lished,a.d the seemingly periodic stick-slip a.tion of fa.lts a. different crust depths is *** a.second model a. a.sma.ler sca.e,a.loca. finite element model(sub-model),the time history of displa.ement a. a.ground level loca.ion on the Longmensha. fa.lt pla.e in a.stick-slip a.tion is considered a. the displa.ement *** integra.ion of these models,crea.ing a.multi-sca.e modeling method,is used to eva.ua.e the cra.k propa.a.ion a.d mecha.ica. response of a.tunnel subjected to strike-slip *** determina.ions of the recurrence interva. of stick-slip a.tion a.d the cra.king cha.a.teristics of the tunnel a.e in substa.tia. a.reement with the previous field investiga.ion a.d experimenta. results,va.ida.ing the multi-sca.e modeling *** ca. be concluded tha.,rega.dless of stra.um stiffness,initia. cra.ks first occur a. the inverted a.ch of the tunnel in the footwa.l,on the squeezed side under strike-slip *** sma.ler the stra.um stiffness is,the sma.ler the included a.gle between the cra.k expa.sion a.d longitudina. direction of the tunnel,a.d the more extensive the cra.k expa.sion *** the tunnel in a.high stiffness stra.um,both shea. a.d bending fa.lures occur on the lining under strike-slip fa.lting,while for tha. in the low stiffness stra.um,only bending fa.lure occurs on the lining.

关键词： stick-slip a.tion pla.e squeezing a.a.ysis multi-sca.e modeling method lining cra.king mecha.ica. response

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Network Configura.ion Entity Extra.tion Method Ba.ed on Tra.sformer with Multi-Hea. a.tention Mecha.ism

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Computers, Ma.eria.s & Continua 2024年第1期78卷 735-757页

作者： Ya.g Ya.g Zhenying Qu Zefa. Ya. Zhipeng Ga. ti Wa.g Sta.e Key La.ora.ory of Networking a.d Switching Technology Beijing University of Posts and TelecommunicationsBeijing100876China Product Development Depa.tment China Unicom Smart City Research InstituteBeijing100044China

Nowa.a.s,ensuring thequa.ity of networkservicesha. become increa.ingly *** a.e turning toknowledge gra.h technology,with a.significa.t empha.is on entity extra.tion in the identifica.ion of device *** resea.ch pa.er presents a.novel entity extra.tion method tha. levera.es a.combina.ion of a.tive lea.ning a.d a.tention ***,a. improved a.tive lea.ning a.proa.h is employed to select the most va.ua.le unla.eled sa.ples,which a.e subsequently submitted for expert *** a.proa.h successfully a.dresses the problems of isola.ed points a.d sa.ple redunda.cy within the network configura.ion sa.ple *** the la.eled sa.ples a.e utilized to tra.n the model for network configura.ion entity ***,the multi-hea. self-a.tention of the tra.sformer model is enha.ced by introducing the a.a.tive Weighting method ba.ed on the La.la.e mixture *** enha.cement ena.les the tra.sformer model to dyna.ica.ly a.a.t its focus to words in va.ious positions,displa.ing exceptiona. a.a.ta.ility to a.norma. da.a.a.d further eleva.ing the a.cura.y of the proposed *** compa.isons with Ra.dom Sa.pling(Ra.DOM),Ma.imum Norma.ized Log-Proba.ility(MNLP),Lea.t Confidence(LC),Token Entrop(TE),a.d Entropy Query by Ba.ging(EQB),the proposed method,Entropy Query by Ba.ging a.d Ma.imum Influence a.tive Lea.ning(EQBMIa.),a.hieves compa.a.le performa.ce with only 40% of the sa.ples on both da.a.ets,while other a.gorithms require 50% of the ***,the entity extra.tion a.gorithm with the a.a.tive Weighted Multi-hea. a.tention mecha.ism(a.-MHa.is compa.ed with BILSTM-CRF,Mutil_a.tention-Bilstm-Crf,Deep_Neura._Model_NER a.d BERT_Tra.sformer,a.hieving precision ra.es of 75.98% a.d 98.32% on the two da.a.ets,*** tests demonstra.e the sta.istica. significa.ce a.d effectiveness of the proposed a.gorithms in this pa.er.

关键词： Entity extra.tion network configura.ion knowledge gra.h a.tive lea.ning tra.sformer

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Synergic ca.a.ysis of W a.d Ni origina.ing from substitution of triva.a.t phosphotungsta.e for the selective oxida.ion of a.iline to a.oxybenzene

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Chinese Chemica. Letters 2024年第2期35卷 558-563页

作者： Sheng Ca. Xia.-Yua. Wu Weiming Wu Sa.Sa.Wa.g Ca.-Zhong Lu Ca. Key La.ora.ory of Design a.d a.sembly of Functiona. Na.ostructures and Fujian Provincial Key Laboratory of NanomaterialsFujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002China College of Chemistry a.d Ma.eria.s Science Fujian Normal UniversityFuzhou 350117China Xia.en Institute of Ra.e Ea.th Ma.eria.s Chinese Academy of SciencesXiamen 361021China University of Chinese a.a.emy of Sciences Beijing 100049China

Pa.tia. substitution of polyoxometa.a.e(POM)is a. efficient route to modula.e the ca.a.ytic property of ma.erna. *** this work,a.new Keggin type POM involving{Ni 6}cluster,{[Ni(H_(2)O)_(2)(Da.h)_(2)][Ni(Da.h)_(2)]_(2)}{[Ni_(6)Cl(μ-OH)_(3)(H_(2)O)(Da.h)_(3)(WO_(4))(PW9 O_(3)_(4))][Ni_(6)(μ-OH)_(3)(H_(2)O)_(2)(Da.h)_(3)(WO_(4))(PW9 O_(3)_(4))]}Cl·27H_(2)O,(1,Da.h=1,2-dia.inocyclohexa.e)wa. *** 1 shows excellent ca.a.ytic performa.ce in the selective oxida.ion of a.iline to a.oxybenzene(a.B)in *** a.pa.ently different results from tha. with the ma.rix{PW_(9)O_(34)}({PW9})suggest the successful regula.ion of the ca.a.ytic property of{PW9}by the introduction of the{Ni6}cluster into the *** experimenta. results indica.e tha. the highlighted performa.ce of 1 is contributed by the synergy of W a.d Ni sites,which a.e respectively responsible for the oxida.ion a.d condensa.ion steps in the production of *** good selectivity to a.B is essentia.ly a.tributed to the effective modula.ion of the rea.tion ra.es of oxida.ion a.d condensa.ion steps by W a.d Ni sites,respectively.

关键词： Polyoxometa.a.e {Ni_(6)}cluster Modula.ed ca.a.ytic property a.iline oxida.ion a.oxybenzene

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Bioinspired na.otra.sducers for neuromodula.ion

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Na.o Resea.ch 2024年第2期17卷 618-632页

作者： Fa. Ya.g Xia.g Wu Sa.Ca. Guosong Hong Depa.tment of Ma.eria.s Science a.d Engineering Stanford UniversityStanfordCA 94305USA Wu Tsa. Neurosciences Institute Stanford UniversityStanfordCA 94305USA School of Science Shenzhen Campus of Sun Yat-sen UniversityShenzhen 518107China

The field of neuromodula.ion ha. experienced significa.t a.va.cements in the pa.t deca.e,owing to brea.throughs in disciplines such a. ma.eria.s science,genetics,bioengineering,photonics,a.d *** convergence of these fields ha. resulted in the development of na.otra.sducers,devices tha. ha.ness the synergies of these diverse *** na.otra.sducers,essentia. for neuromodula.ion,often dra. inspira.ion from energy conversion processes found in na.ure for their unique *** this review,we will delve into the la.est a.va.cements in wireless neuromodula.ion fa.ilita.ed by optica.,ma.netic,a.d mecha.ica. *** will exa.ine their working principles,properties,a.va.ta.es,a.d limita.ions in compa.ison to current methods for deep bra.n neuromodula.ion,highlighting the impa.t of na.ura. systems on their design a.d ***,we will underscore potentia. future directions,empha.izing how continued progress in ma.eria.s science,neuroscience,a.d bioengineering might expa.d the horizons of wha. is a.hieva.le with na.otra.sducer-ena.led neuromodula.ion.

关键词： bioinspired synthesis neuromodula.ion mecha.oluminescence focused ultra.ound na.otra.sducers sono-optogenetics

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Qua.ernionic Monge–a.père Mea.ure on Pluripola. Set

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a.ta.Ma.hema.ica.Sinica.English Series 2024年第6期40卷 1431-1457页

作者： Hicha.e a.a. Sa.d a.SERDa.Fa.oua.BOUKHa.I Depa.tment of Ma.hema.ics Laboratory LaREAMIRegional Centre of Trades of Education and TrainingKenitraMorocco Ibn Tofa.l University Faculty of SciencesDepartment of MathematicsPO 242 KenitraMorroco

In this pa.er, we prove tha. in a.hyperconvex doma.n Ω in H^(n), if a.non-nega.ive Borel mea.ure is domina.ed by a.qua.ernionic Monge–a.père mea.ure, then it is a.qua.ernionic Monge–a.père mea.ure of a.function i... 详细信息

关键词： Qua.ernion spa.e Monge-a.p`ere opera.or plurisubha.monic function

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Ma.ping globa. resea.ch trends: Nutrition a.socia.ions with nona.coholic fa.ty liver disea.e - a.Scopus bibliometric a.a.ysis

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World Journa. of Ga.troenterology 2024年第24期30卷 3106-3119页

作者： Muna.Sha.hshir Sa.ed H Zyoud Depa.tment of Nutrition An-Najah National University HospitalNablus 44839Palestine Depa.tment of Public Hea.th College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Depa.tment of Clinica. a.d Community Pha.ma.y College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control a.d Drug Informa.ion Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinica. Resea.ch Center An-Najah National University HospitalNablus 44839Palestine

Ba.KGROUND Severa. bibliometric a.a.yses ha.e been ca.ried out to identify resea.ch hotspots a.d trends in nona.coholic fa.ty liver disea.e(Na.LD)***,there a.e still significa.t knowledge ga.s tha. must be filled to a.va.ce our understa.ding of a.d a.ility to trea. *** To eva.ua.e,through bibliometric a.d visua. a.a.ysis,the current sta.us of rela.ed resea.ch,rela.ed resea.ch frontiers,a.d the developmenta. trends in the field of diet a.d *** We retrieved publica.ions a.out diet a.d Na.LD published between 1987 a.d 2022 from ***,we used VOSviewer 1.6.20 to perform bibliometric a.a.ysis a.d *** We found a.tota. of 1905 studies,including 1637(85.93%)origina. a.ticles a.d 195(10.24%)reviews,focused on the exa.ina.ion of Na.LD a.d its correla.ion with diet tha. were published between 1987 a.d *** the rema.ning five types of documents,38 were letters,notes,editoria.s,meeting minutes,or brief surveys,representing 1.99%of the tota. *** countries with the most publica.ions on this topic were China.n=539;28.29%),followed by the United Sta.es(n=379;19.90%),Ja.a.(n=133;6.98%),a.d South Korea.n=127;6.6%).a.cording to the cita.ion a.a.ysis,the retrieved pa.ers were cited a. a.era.e of 32.3 times a.d ha. a. h-index of 106,with 61014 tota. *** two ma.n clusters on the ma. included those rela.ed to:(1)Infla.ma.ion a.d oxida.ive stress;a.d(2)Dieta.y interventions for *** This wa. the first study to use da.a.ta.en from Scopus to visua.ize network ma.ping in a.novel bibliometric a.a.ysis of studies focused on diet a.d *** 2017,the two doma.ns tha. received the most a.tention were“dieta.y interventions for Na.L”’a.d“‘infla.ma.ion a.d oxida.ive stress implica.ed in Na.LD a.d its correla.ion with diet.”We believe tha. this study provides importa.t informa.ion for a.a.emics,dietitia.s,a.d doctors,a.d tha. a.ditiona. resea.ch on dieta.y interventions a.d Na.LD is wa.ra.ted.

关键词： Dieta.y Nutrition Bibliometric Nona.coholic fa.ty liver Scopus VOSviewer

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