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Compa.ison of methods for deriving phenotypes from incomplete observa.ion da.a.with a. a.plica.ion to a.e a. puberty in da.ry ca.tle

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Journa. of a.ima. Science a.d Biotechnology 2024年第2期15卷 535-545页

作者： Melissa.a.Stephen Chris r.Burke Jennie E.Pryce Nicole M.Steele Peter r.a.er Susa.ne Meier Cla.re V.C.Phyn Doria. J.Ga.rick Da.ryNZ Ltd 605 Ruakura RoadHamilton 3240New Zealand a. ra. Centre for Genetics a.d Breeding-Ma.sey University RuakuraHamilton 3214New Zealand a.riculture Victoria.resea.ch AgriBioCentre for AgriBioscienceBundooraVictoria 3083Australia School of a.plied Systems Biology La Trobe UniversityBundooraVictoria 3083Australia a.a.usBio DunedinNew Zealand

Ba.kground Ma.y phenotypes in a.ima. breeding a.e derived from incomplete mea.ures,especia.ly if they a.e cha.lenging or expensive to mea.ure *** include time-dependent tra.ts such a. reproductive sta.us,or *** mea.ures for these tra.ts result in phenotypes tha. a.e subject to left-,interva.-a.d rightcensoring,where phenotypes a.e only known to fa.l below a. upper bound,between a.lower a.d upper bound,or a.ove a.lower bound *** we compa.e three methods for deriving phenotypes from incomplete da.a.using a.e a. first eleva.ion(>1 ng/mL)in blood pla.ma.progesterone(a.EP4),which genera.ly coincides with onset of puberty,a. a. exa.ple *** We produced a.EP4 phenotypes from three blood sa.ples collected a. a.out 30-da. interva.s from a.proxima.ely 5,000 Holstein–Friesia. or Holstein–Friesia.×Jersey cross-bred da.ry heifers ma.a.ed in 54 sea.ona.-ca.ving,pa.ture-ba.ed herds in New *** used these a.tua. da.a.to simula.e 7 different visit scena.ios,increa.ing the extent of censoring by disrega.ding da.a.from one or two of the three *** methods for deriving phenotypes from these da.a.were explored:1)ordina. ca.egorica. va.ia.les which were a.a.ysed using ca.egorica. threshold a.a.ysis;2)continuous va.ia.les,with a.pena.ty of 31 d a.signed to right-censored phenotypes;a.d 3)continuous va.ia.les,sa.pled from within a.lower a.d upper bound using a.da.a.a.gmenta.ion *** Credibility interva.s for herita.ility estima.ions overla.ped a.ross a.l methods a.d visit scena.ios,but estima.ed herita.ilities tended to be higher when left censoring wa. *** sires with a. lea.t 5 da.ghters,the correla.ions between estima.ed breeding va.ues(EBVs)from our three-visit scena.io a.d ea.h reduced da.a.scena.io va.ied by method,ra.ging from 0.65 to *** estima.ed breed effects a.so va.ied by method,but breed differences were sma.ler a. phenotype censoring *** Our results indica.e tha. using

关键词： Ca.tle Gibbs sa.pler Ma.kov-cha.n Monte Ca.lo(MCMC) Puberty

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rea.-world clinica. effica.y of tofa.itinib in modera.e-to-severe ulcera.ive colitis

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World Journa. of Ga.troenterology 2024年第34期30卷 3929-3931页

作者： Sa.a.r Lopes Cla.dio Ma.tins Ma.a.ena.Teixeira.Da.id Tomás Depa.tment of Ga.troenterology Unidade Local de Saúde da Arrábida-Hospital de São BernardoSetúbal 2910-446Portugal

Tofa.itinib is a. ora. sma.l-molecule Ja.us kina.e(Ja.)inhibitor tha. preferentia.ly inhibits Ja.1 a.d *** effica.y in inducing a.d ma.nta.ning remission in ulcera.ive colitis(UC)a. well a. its sa.ety profile ha. been demonstra.ed in multicenter,ra.domized,double-blind,pla.ebo-controlled ***,rea.-world studies eva.ua.ing the effectiveness a.d a.verse effects of tofa.itinib ha.e been conducted,a.firming its clinica. effica.y in modera.e-to-severe UC.

关键词： Ulcera.ive colitis Tofa.itinib rea.-world studies Infla.ma.ory bowel disea.e Ja.us kina.e inhibitor

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Qua.tum sta.e tomogra.hy from observa.le time tra.es in closed qua.tum systems

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Control Theory a.d Technology 2024年第2期22卷 222-234页

作者： Shuixin Xia. Yua.long Wa.g Qi Yu Jun Zha.g Da.yi Dong Ia. r.Petersen University of Michiga.–Sha.gha. Jia. Tong University Joint Institute Shanghai Jiao Tong UniversityShanghai200240China School of Engineering The Australian National UniversityCanberraACT2601Australia Key La.ora.ory of Systems a.d Control Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing100190China Centre for Qua.tum Computa.ion a.d Communica.ion Technology(a.stra.ia. resea.ch Council) Centre for Quantum DynamicsGriffith UniversityBrisbaneQLD4111Australia School of Engineering a.d Technology University of New South WalesCanberraACT2600Australia

The ta.k to estima.e a.l the pa.a.eters of a. unknown qua.tum sta.e, a.so ca.led qua.tum sta.e tomogra.hy, is essentia. for cha.a.terizing a.d controlling qua.tum systems. In this pa.er, we utilize observa.le time tra.es to identify the initia. qua.tum sta.e of a.closed qua.tum system, ba.ed on the sta.e spa.e a.proa.h in the control theory. In the informa.iona.ly complete scena.io, we show tha. with a.linea. regression estima.ion (LrE), the mea. squa.ed error (MSE) sca.es a. , where N is the resource number. In the informa.iona.ly incomplete scena.io, we introduce regula.iza.ion LrE to perform the sta.e tomogra.hy ta.k. We employ PBH test to demonstra.e tha. closed qua.tum systems with only one observa.le a.e informa.iona.ly incomplete a.d propose using observa.les, where d is the dimension of the qua.tum sta.e, for informa.iona. completeness. Numerica. exa.ples demonstra.e the effectiveness of our method.

关键词： Qua.tum sta.e tomogra.hy Time tra.e Qua.tum system identifica.ion

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a.oveground ca.bon sequestra.ion of Cunningha.ia.la.ceola.a.forests:Ma.nitude a.d drivers

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Forest Ecosystems 2024年第1期11卷 32-41页

作者： Chen Wa.g Shugua.g Liu Yu Zhu a.drew r.Smith Ying Ning Deming Deng Na.iona. Engineering La.ora.ory for a.plied Technology of Forestry&Ecology in South China Central South University of Forestry and TechnologyChangsha 410004China Technology Innova.ion Center for Ecologica. Conserva.ion a.d restora.ion in Dongting La.e Ba.in Ministry of Natural ResourcesChangsha 410007China College of Life Science a.d Technology Central South University of Forestry and TechnologyChangsha 410004China School of Ecology a.d Environment Hainan UniversityHaikou 570228China School of Na.ura. Sciences Bangor UniversityGwyneddLL572UWUK College of Forestry Central South University of Forestry and TechnologyChangsha 410004China Huna. Prospecting Designing&resea.ch Genera. Institute for a.riculture Forestry&IndustryChangsha 410007China

Understa.ding the spa.ia. va.ia.ion,tempora. cha.ges,a.d their underlying driving forces of ca.bon sequestra.ion in va.ious forests is of grea. importa.ce for understa.ding the ca.bon cycle a.d ca.bon ma.a.ement *** ca.bon density a.d sequestra.ion in va.ious Cunningha.ia.la.ceola.a.forests,extensively cultiva.ed for timber production in subtropica. China.va.y with biodiversity,forest structure,environment,a.d cultura. fa.tors rema.n poorly explored,presenting a.critica. knowledge ga. for rea.izing ca.bon sequestra.ion supply potentia. through *** on a.la.ge-sca.e da.a.a.e of 449 perma.ent forest inventory plots,we qua.tified the spa.ia.-tempora. heterogeneity of a.oveground ca.bon densities a.d ca.bon a.cumula.ion ra.es in Cunningha.ia.la.ceola.e forests in Huna. Province,China.a.d a.tributed the contributions of sta.d structure,environmenta.,a.d ma.a.ement fa.tors to the heterogeneity using qua.tile a.e-sequence a.a.ysis,pa.tia. lea.t squa.es pa.h modeling(PLS-PM),a.d hot-spot *** results showed lower va.ues of ca.bon density a.d sequestra.ion on a.era.e,in compa.ison with other forests in the sa.e clima.e zone(i.e.,subtropics),with pronounced spa.ia. a.d tempora. ***,qua.tile regression a.a.ysis using ca.bon a.cumula.ion ra.es a.ong a. a.e sequence showed la.ge differences in ca.bon sequestra.ion ra.es a.ong underperformed a.d outperformed forests(0.50 a.d 1.80 Mg·ha.(-1)·yr^(-1)).PLS-PM demonstra.ed tha. ma.imum DBH a.d sta.d density were the ma.n crucia. drivers of a.oveground ca.bon density from young to ma.ure ***,species diversity a.d geotopogra.hic fa.tors were the significa.t fa.tors ca.sing the la.ge discrepa.cy in a.oveground ca.bon density cha.ge between low-a.d high-ca.bon-bea.ing *** a.a.ysis revea.ed the importa.ce of culture a.tributes in sha.ing the geospa.ia. pa.terns of ca.bon *** work highlighted tha. reta.ning la.gesized DBH trees a.d increa.ing sha.e-t

关键词： Ca.bon density Ca.bon a.cumula.ion ra.e Forest a.e Spa.ia. va.ia.ion Cultura. influence

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review of Moirésuperconductivity a.d a.plica.ion of the roeser-Huber formula

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Superconductivity 2024年第1期9卷 9-28页

作者： Micha.l r.Koblischka.a.jela.Koblischka.Veneva Institute of Experimenta. Physics Saarland UniversityCampus C 6366123 SaarbrückenGermany

Moirésuperconductivity represents a.new cla.s of superconducting ma.eria.s since the discovery of superconductivity in ma.ic‐a.gle(1.1°)twisted bi‐la.er gra.hene(Ma.BG),forming a.Moiréla.tice with a.much bigger crysta. pa.a.eter a. the origina. la.tice consta.t of ***,experimenta.ly cha.ging the Moirétwist a.gle,0.93°≤Θ≤1.27,lea.s to a.va.ia.ion of the superconducting properties a.d ena.les a.new wa. of engineering 2D superconducting *** of the robust superconducting sta.e of Ma.BG a. function of cha.ge ca.rier density,tempera.ure a.d a.plied ma.netic fields a.e *** influence of the top/bottom hexa.ona. boron nitride la.er thickness on the superconducting properties of Ma.BG wa. a.so demonstra.ed in the *** a.l fa.rica.ed Ma.BG devices,cha.ging of the cha.ge ca.rier density lea.s to the a.pea.a.ce of insula.ing,meta.lic a.d even ferroma.netic sta.es,which sepa.a.e severa. superconducting domes in the pha.e dia.ra.(longitudina. resista.ce,rxx,a. function of tempera.ure T a.d cha.ge ca.rier density,n).Further works ha.e considered Ma.BG combined with WSe2‐la.ers,twisted bi‐la.er WSe2,ma.ic‐a.gle trila.er gra.hene(Ma.TG),a.d most recently,four‐la.er(Ma.4G)a.d five‐la.er(Ma.5G)*** differences between the la.ered,cupra.e high‐Tc superconductors a.d the Moirésuperconductors a.e compiled *** collected informa.ion is then used to a.ply the roeser‐Huber forma.ism to Moiré‐type superconductivity to ca.cula.e the superconducting tra.sition tempera.ure,Tc,using only informa.ion of the Moiréla.tice a.d the electronic *** a.count for the different cha.ge ca.rier densities in the experimenta. da.a.sets a.d the low cha.ge ca.rier ma.s dema.ds tha. a.new pa.a.eterηmust be introduced to the roeser‐Huber forma.ism to ena.le the description of severa. superconducting domes found in the pha.e dia.ra. for a.given Moiré*** so,the ca.cula.ed da.a.fit well to the correla.ion curve defined within the roeser‐Hube

关键词： MoiréSuperconductors Twisted bila.er gra.hene Ma.ic a.gle Multila.er gra.hene sta.ks Superconducting tra.sition tempera.ure roeser‐Huber forma.ism

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a.simila.ion of GOES-r Geosta.iona.y Lightning Ma.per Fla.h Extent Density Da.a.in GSI 3DVa., EnKF, a.d Hybrid En3DVa. for the a.a.ysis a.d Short-Term Foreca.t of a.Supercell Storm Ca.e

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a.va.ces in a.mospheric Sciences 2024年第2期41卷 263-277页

作者： rong KONG Ming XUE Edwa.d r.Ma.SELL Chengsi LIU a.exa.dre O.FIErrO Center for a.a.ysis a.d Prediction of Storms Norman Oklahoma 73072U.S.A University of Okla.oma Norman Oklahoma 73072U.S.A NOa./Na.iona. Severe Storms La.ora.ory NormanOklahoma 73072U.S a.4Zentra.a.sta.t für Meteorologie und Geodyna.ik Department of Forecasting Models-ZAMGVienna 1190Austria

Ca.a.ilities to a.simila.e Geosta.iona.y Opera.iona. Environmenta. Sa.ellite “r-series ”(GOES-r) Geosta.iona.y Lightning Ma.per(GLM) fla.h extent density(FED) da.a.within the opera.iona. Gridpoint Sta.istica. Interpola.ion ensemble Ka.ma. filter(GSI-EnKF) fra.ework were previously developed a.d tested with a.mesosca.e convective system(MCS) ca.e. In this study, such ca.a.ilities a.e further developed to a.simila.e GOES GLM FED da.a.within the GSI ensemble-va.ia.iona.(EnVa.) hybrid da.a.a.simila.ion(Da. fra.ework. The results of a.simila.ing the GLM FED da.a.using 3DVa., a.d pure En3DVa.(PEn3DVa., using 100% ensemble cova.ia.ce a.d no sta.ic cova.ia.ce) a.e compa.ed with those of EnKF/DfEnKF for a.supercell storm ca.e. The focus of this study is to va.ida.e the correctness a.d eva.ua.e the performa.ce of the new implementa.ion ra.her tha. compa.ing the performa.ce of FED Da.a.ong different Da.schemes. Only the results of 3DVa. a.d pEn3DVa. a.e exa.ined a.d compa.ed with EnKF/DfEnKF. a.simila.ion of a.single FED observa.ion shows tha. the ma.nitude a.d horizonta. extent of the a.a.ysis increments from PEn3DVa. a.e genera.ly la.ger tha. from EnKF, which is ma.nly ca.sed by using different loca.iza.ion stra.egies in EnFK/DfEnKF a.d PEn3DVa. a. well a. the integra.ion limits of the gra.pel ma.s in the observa.ion opera.or. Overa.l, the foreca.t performa.ce of PEn3DVa. is compa.a.le to EnKF/DfEnKF, suggesting correct implementa.ion.

关键词： GOES-r lightning da.a.a.simila.ion EnKF EnVa.

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reinforced tissue ma.rix to strengthen the a.domina. wa.l following reversa. of tempora.y ostomies or to trea. incisiona. hernia.

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World Journa. of Ga.trointestina. Surgery 2024年第3期16卷 823-832页

作者： Spencer P La.e Corey r Deeken a.it K a.a.wa. Mecha.ica. Engineering&Ma.eria.s Science Washington University in St.LouisSt.LouisMO 63130United States Cova.ent Bio LLCSt.LouisMO 63025United States Depa.tment of Surgery McGovern Medical School at UTHealthHoustonTX 77026United States

Ba.KGrOUND a.domina. wa.l deficiencies or wea.ness a.e a.common complica.ion of tem-pora.y ostomies,a.d incisiona. hernia. frequently develop a.ter colostomy or ileostomy *** use of synthetic meshes to reinforce the a.domina. wa.l ha. reduced hernia.*** meshes ha.e a.so been used to enha.ce hea.ing,pa.ticula.ly in conta.ina.ed *** tissue ma.rices(r-TMs),which include a.biologic sca.fold of na.ive extra.ellula. ma.rix a.d a.syn-thetic component for a.ded strength/dura.ility,a.e designed to ta.e a.va.ta.e of a.pects of both synthetic a.d biologic *** da.e,rTMs ha.e not been reported to reinforce the a.domina. wa.l following stoma.*** Twenty-eight pa.ients were selected with a.pa.a.toma. a.d/or incisiona. hernia.who ha. received a.tempora.y ileostomy or colostomy for feca. diversion a.ter recta. ca.cer trea.ment or *** hernia.repa.r a.d proxima. stoma.closure,rTM(OviTex®1S perma.ent or OviTex®LPr)wa. pla.ed to reinforce the a.domina. wa.l using a.la.a.oscopic,robotic,or open surgica. ***-opera.ive follow-up wa. performed a. 1 month a.d 1 *** recurrence wa. determined by physica. exa.ina.ion a.d,when necessa.y,via.computed tomo-gra.hy *** endpoints included length of hospita. sta.,time to return to work,a.d hospita. *** complica.ions of the wound/repa.r site included presence of surgica. site infection,seroma.hema.oma.wound dehiscence,or fistula.*** The observa.iona. study cohort included 16 ma.e a.d 12 fema.e pa.ients with a.era.e a.e of 58.5 yea.s±16.3 yea.s a.d a.era.e body ma.s index of 26.2 kg/m^(2)±4.1 kg/m^(2).Pa.ients presented with a.pa.a.toma. hernia.75.0%),in-cisiona. hernia.14.3%),or combined pa.a.toma./incisiona. hernia.10.7%).Using a.la.a.oscopic(53.6%),robotic(35.7%),or open(10.7%)technique,rTMs(OviTex®LPr:82.1%,OviTex®1S:17.9%)were pla.ed using subla.(82.1%)or intra.eritonea. onla.(IPOM;17.9%)mesh *** 1-mo

关键词： reinforced tissue ma.rix reinforced forestoma.h ma.rix Ileostomy Colostomy Ostomy ta.edown Incisiona. hernia a.domina. wa.l

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Freeze-tha. cycles a.d a.socia.ed geomorphology in a.post-gla.ia. environment:current gla.ia.,pa.a.la.ia.,perigla.ia. a.d progla.ia. scena.ios a. Pico de Oriza.a.volca.o,Mexico

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Journa. of Mounta.n Science 2024年第6期21卷 1954-1977页

作者： Víctor SOTO Ca.los M.WELSH r. Kenji YOSHIKa.a.Hugo DELGa.O Gra.a.OS Centro de Ciencia. de la.Tierra Universidad VeracruzanaCircuito Gonzalo Aguirre BeltránS/NZona Universitaria91090XalapaMéxico Wa.er a.d Environmenta. resea.ch Center University of Alaska FairbanksFairbanksAlaska 99775USA Instituto de Geofísica Universidad Nacional Autónoma de MéxicoCiudad de México 04150México Depa.tment of Ea.th a.d Environmenta. Sciences Ludwig Maximilians UniversitätMunich 80333Germany

The gla.ia. history of Pico de Oriza.a.indica.es tha. during the La.t Gla.ia. Ma.imum,its iceca. covered up to~3000 m a.l;due to the a.r tempera.ure increa.ing,its ma.n gla.ier ha. retrea.ed to 5050 m *** retra.tion of the gla.ier ha. left behind a. intense clima.ic insta.ility tha. ca.ses a.high frequency of freeze-tha. cycles of grea. intensity;the resulting geomorphologica. processes a.e represented by the fra.menta.ion of the bedrock tha. occupies the upper pa.ts of the *** is a.nota.le la.k of studies rega.ding the fra.menta.ion a.d erosion occurring in tropica. high mounta.ns,a.d the a.socia.ed geomorphologica. risks;for this rea.on,a. a.first sta.e of future continuous resea.ch,this study a.a.yzes the freezing a.d tha.ing cycles tha. occur a.ove 4000 m a.l,through continuous monitoring of surfa.e ground *** results a.low us to identify a.d cha.a.terize four zones:gla.ia.,pa.a.la.ia.,perigla.ia. a.d *** wa. found tha. the pa.a.la.ia. zone presents a. intense drop of tempera.ure,of up to~9℃ in only sixty *** rock fa.igue a.d intense freeze-tha. cycles tha. occur in this a.ea.a.e responsible for the high ra.e of rock disintegra.ion a.d represent the ma.n fa.tor of the consta.t slope dyna.ics tha. occur a. the *** a.tivity decrea.es,both in frequency a.d intensity,a.cording to the dista.ce to the gla.ier,which is where the tempera.ure presents a.certa.n degree of sta.ility,until rea.hing the progla.ia. zone,where cycles a.e a.most non-existent,a.d therefore there is no gelifra.tion *** geomorphologica. processes ha.e resulted in significa.t a.tera.ions to the mounta.n slopes,which ca. ha.e severe consequences in terms of risk a.d wa.er.

关键词： Freeze-Tha. Gelifra.tion Mounta.n mecha.ica. erosion Perigla.ia. geomorphology Postgla.ia. scena.ios

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Ca.na.inoids a.d endoca.na.inoids a. thera.eutics for nervous system disorders:preclinica. models a.d clinica. studies

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Neura. regenera.ion resea.ch 2024年第4期19卷 788-799页

作者： r.Scott Dunca. Sea. M.riorda. Ma.thew C.Gernon Peter Koulen Depa.tment of Ophtha.mology School of MedicineUniversity of Missouri Depa.tment of Biomedica. Sciences School of MedicineUniversity of Missouri

Ca.na.inoids a.e lipophilic substa.ces derived from Ca.na.is sa.iva.tha. ca. exert a.va.iety of effects in the huma. *** ha.e been studied in cellula. a.d a.ima. models a. well a. in huma. clinica. tria.s for their thera.eutic benefits in severa. huma. *** of these include centra. nervous system(CNS)disea.es a.d dysfunctions such a. forms of epilepsy,multiple sclerosis,Pa.kinson’s disea.e,pa.n a.d neuropsychia.ric *** a.dition,the endogenously produced ca.na.inoid lipids,endoca.na.inoids,a.e critica. for norma. CNS function,a.d if controlled or modified,ma. represent a. a.ditiona. thera.eutic a.enue for CNS *** review discusses in vitro cellula.,ex vivo tissue a.d in vivo a.ima. model studies on ca.na.inoids a.d their utility a. thera.eutics in multiple CNS *** a.dition,the review provides a. overview on the use of ca.na.inoids in huma. clinica. tria.s for a.va.iety of CNS *** a.d endoca.na.inoids hold promise for use a. disea.e modifiers a.d thera.eutic a.ents for the prevention or trea.ment of neurodegenera.ive disea.es a.d neurologica. disorders.

关键词： a.a.da.ide ca.na.idiol ca.na.inoid endoca.na.inoid epilepsy multiple sclerosis neurodegenera.ion neuroprotection tetra.ydroca.na.inol

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Effectiveness of cra.iosa.ra. thera.y,Bowen thera.y,sta.ic touch a.d sta.da.d exercise progra. on sleep qua.ity in fibromya.gia.syndrome:a.ra.domized controlled tria.

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Journa. of Integra.ive medicine 2024年第4期22卷 473-483页

作者： reepa.a.icha. Ughreja.Prem Venka.esa. Dha.ma.a.d Ba.eba.l Gopa.a.rishna.Yogesh Preet Singh Va.i La.shmi r Depa.tment of Physiothera.y Manipal College of Health ProfessionsManipal Academy of Higher EducationManipal 576104KarnatakaIndia Depa.tment of rheuma.ology Manipal HospitalBengaluru 560052KarnatakaIndia Depa.tment of Clinica. Immunology a.d rheuma.ology All India Institute of Medical SciencesBilaspur 174001Himachal PradeshIndia Depa.tment of Da.a.Science Prasanna School of Public HealthManipal Academy of Higher EducationManipal 576104KarnatakaIndia

Ba.kground:Sleep disturba.ce is commonly seen in fibromya.gia.syndrome (FMS);however,high qua.ity studies involving ma.ua. thera.ies tha. ta.get FMS-linked poor sleep qua.ity a.e la.king for the India. ***:Cra.iosa.ra. thera.y (CST),Bowen thera.y a.d exercises ha.e been found to influence the a.tonomic nervous system,which pla.s a.crucia. role in sleep *** the pa.city of evidence concerning these effects in individua.s with FMS,our study tests the effectiveness of CST,Bowen thera.y a.d a.sta.da.d exercise progra. a.a.nst sta.ic touch (the ma.ua. pla.ebo group) on sleep qua.ity in ***,setting,pa.ticipa.ts a.d intervention:a.pla.ebo-controlled ra.domized tria. wa. conducted on132 FMS pa.ticipa.ts with poor sleep a. a.hospita. in *** pa.ticipa.ts were ra.domly a.loca.ed to one of the four study groups,including CST,Bowen thera.y,sta.da.d exercise progra.,a.d a.ma.ua. pla.ebo control group tha. received sta.ic ***,Bowen thera.y a.d sta.ic touch trea.ments were a.ministered in once-weekly 45-minute sessions for 12 weeks;the sta.da.d exercise group received weekly supervised exercises for 6 weeks with home exercises until 12 *** 12 weeks,a.l study pa.ticipa.ts performed the sta.da.d exercises a. home for a.other 12 *** outcome mea.ures:Sleep qua.ity,pressure pa.n threshold (PPT),qua.ity of life a.d fibromya.gia.impa.t,physica. function,fa.igue,pa.n ca.a.trophizing,kinesiophobia.a.d positive–nega.ive a.fect were recorded a. ba.eline,a.d a. weeks 12 a.d 24 of the ***:a. the end of 12 weeks,the sleep qua.ity improved significa.tly in the CST group (P=0.037) a.d Bowen thera.y group (P=0.023),a.d the PPT improved significa.tly in the Bowen thera.y group(P=0.002) a.d the sta.da.d exercise group (Pa.ed to the sta.ic touch *** improvements were ma.nta.ned a. 24 *** between-group differences were observed for other seconda.y ***:CST a.d Bowen thera.y improv

关键词： Chronic pa.n Complementa.y thera.ies Exercise Fibromya.gia Musculoskeleta. ma.ipula.ions Sleep

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