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Growth characteristics and pathogenic consequences of predominant entomopathogenic Yukon soil fungi Mortierella alpina and Penicillium expansum,and effectiveness of Met52®,against larvae of the winter tick,Dermacentor albipictus

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Studies in Fungi 2019年第1期4卷 101-110页

作者： Yoder ja Krieger M Oakley M Trotter J Schmelzer P Niksic A Rodell BM Klever la Department of Biology Wittenberg UniversitySpringfieldOH45501USA Champagne and Aishihik First Nations Haines JunctionYTY0B 1L0CAN Oakley Veterinary Services HainesAK99827USA

Water activity-temperature relationships are reported for Yukon soil-isolated strains of Mortierella alpina and Penicillium expansum that are natural enemies to larvae(infestation stage)of the winter tick Dermacentor *** fungal strains are psychrotrophs,characterized by low thermal growth ranges,consistent with their occurrence in Yukon *** contrast to ***,*** is more temperature sensitive,has a higher requirement,and is more virulent to tick *** and Biological Control Officers should note that for tick population control these *** and *** strains grow and sporulate well under moderate temperature and humid *** experiments used Met52®Bioinsecticide as a positive control,and this is the first study that demonstrates the effectiveness of this commercial product against winter tick larvae.

关键词： Alaska biological control Canada elk tick horse tick moose tick temperature water activity

Ischemic colitis after mesotherapy combined with anti-obesity medications

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World Journal of Gastroenterology 2010年第12期16卷 1537-1540页

作者： Jong Bin Kim Won Moon Seun ja Park Moo In Park Kyu-Jong Kim jae Nam Lee Seong Joo Kang Lee la jang Hee Kyung Chang Department of Internal Medicine Kosin University College of Medicine Department of Pathology Kosin University College of Medicine

Mesotherapy and anti-obesity medications are gradually gaining worldwide popularity for purposes of body contouring and weight *** adverse effects are various,but there is a tendency to disregard *** colitis is one of the most common diseases associated with non-obstructive blood vessel ***,there have been no case reports about the adverse effects resulting from mesotherapy only or in combination with anti-obesity *** report on an interesting case of ischemic colitis after mesotherapy combined with anti-obesity medications in a 39-year-old female who had no risk factors.

关键词： Mesotherapy Anti-obesity medications Adverse effects Ischemic colitis

Entomopathogenic fungi isolated from Yukon soil against unfed larvae of the winter tick,Dermacentor albipictus

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Studies in Fungi 2019年第1期4卷 123-134页

作者： Dobrotka CJ Krieger M Oakley M Trotter J Rodell BM Stein KL Klever la Fisher KA Yoder ja Department of Biology Wittenberg UniversitySpringfieldOH45501USA Champagne and Aishihik First Nations Haines JunctionYTY0B 1L0CAN Oakley Veterinary Services HainesAK99827USA

Fungal composition of Yukon soil samples consisted of 29 soil saprobes common to acidified forest,subarctic *** of the fungi identified are psychrotrophs,capable of growth at both 4℃ and 20℃.Of these,a total of 17 fungi were found to be entomopathogenic by winter tick(Dermacentor albipictus)larval bioassays:Aspergillus flavus,Beauveria,namely ***,Mucor,Paecilomyces yielded>~70%larval mortality and the remainder,mostly Mortierella and Penicillium,averaged~40%larval *** where elk(Cervus elaphus canadensis)are observed had an overall greater quantity,and diversity of entomopathogenic soil fungi than sites where elk are not *** diversity of fungi at elk-inhabited sites is likely a product of warmer soil microclimate(hillsides where elk are seen,lose snow earlier than other areas),animal presence,and increased nutrient *** conclude that Yukon soils contain fungi that naturally regulate populations of *** fungi are archived at the Wittenberg University Fungus Collection,Springfield,OH,USA.

关键词： Biological control mycoflora moose tick elk tick horse tick Canada Alaska

Dependence of dynamic contour and Goldmann applanation tonometries on peripheral corneal thickness

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International Journal of Ophthalmology(English edition) 2017年第10期10卷 1521-1527页

作者： Federico Saenz-Frances Claudia Sanz-Pozo lara Borrego-Sanz Luis ja?ez laura MoralesFernandez Jose Maria Martinez-de-la-Casa Julian Garcia-Sanchez Julian Garcia-Feijoo Enrique Santos-Bueso Ophthalmology Department Clinico Universitario San Carlos HospitalComplutense University Institute of Knowledge Technology Complutense University

AIM：To determine the effects of peripheral corneal thickness（PCT）on dynamic contour tonometry（DCT）and Goldmann applanation tonometry（GAT）.METHODS：A cross-sectional *** created a software which calculates the corneal contour（CC）as a function of the radius from the corneal apex to each pixel of the *** software generates a central circumference with a radius of 1 mm and the remainder of the cornea is segmented in 5 rings concentric with corneal apex being its diameter not constant around the corneal circumference as a consequence of the irregular CC but keeping constant the diameter of each ring in each direction of the *** was determined as the mean thickness of the most eccentric *** weighted scatterplot smoothing（LOWESS）regression was used to determine the pattern of the relationship between PCT and both DCT and GAT ***,two multivariable linear regression models were *** each of them,the dependant variable was intraocular pressure（IOP）as determined using GAT and DCT *** both of the models the predictive variable was PCT though LOWESS regression pattern was used to model the relationship between the dependant variables and the predictor *** and sex were also introduced control variables along with their first-degree interactions with *** outcome measures include amount of IOP variation explained through regression models（R2）and regression coefficients（B）.RESULTS：Subjects included 109 eyes of 109 healthy *** regression suggested that a 2nd-degree polynomial would be suitable to model the relationshipbetween both DCT and GAT with *** PCT was introduced in both models as a linear and quadratic *** age nor sex nor interactions were statistically significant in both *** GAT model,R2was 17.14%（F=9.02;P=0.0002）,PCT linear term B was-1.163（95%CI：-1.163,-0.617）.PCT quadratic term B was 0.00081（95%CI：0.00043,0.00118）.For DCT model R2was 14.28%（F=9.29;P=0.0002

关键词： Goldmann applanation tonometry dynamic contour tonometry peripheral corneal thickness corneal thickness

TCRγδ—是多余的T细胞亚群,还是免疫系统的特殊成分?

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国外医学（免疫学分册） 1990年第6期13卷 315-317页

作者： Bluestone ja Matis la 朱炳法

免疫学家在研究TCRαβ介导免疫识别的发育及结构的同时发现了一类新的T细胞亚群,它既不同于CD_8^+溶细胞性TCRαβ细胞,又不同于CD_4^+辅助性TCRαβ细胞,它由二硫键联结γ-和δ-基因产物(γ、δ键)组成。笔者近几年来着重研究TCRαβ... 详细信息

免疫学家在研究TCRαβ介导免疫识别的发育及结构的同时发现了一类新的T细胞亚群,它既不同于CD_8^+溶细胞性TCRαβ细胞,又不同于CD_4^+辅助性TCRαβ细胞,它由二硫键联结γ-和δ-基因产物(γ、δ键)组成。笔者近几年来着重研究TCRαβ细胞的胚系发生、多样性及其分子结构。众所周知,TCRγ基因是Tonegawa 等在寻求TCRαβ二聚体中α基因重排时发现的,γ基因虽可从TCRαβ细胞中分离到。

关键词： TCRγδ T细胞亚群免疫系统

Organosolv Lignin for Non-Isocyanate Based Polyurethanes (NIPU) as Wood Adhesive

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Journal of Renewable Materials 2021年第5期9卷 881-907页

作者： jaša Saražin Antonio Pizzi Siham Amirou Detlef Schmiedl MilanŠernek Biotechnical Faculty University of LjubljanaLjubljana1000Slovenia LERMAB-ENSTIB Universitéde LorraineEpinal88000France Fraunhofer Institute for Chemical Technology Pfinztal76327Germany

A non-isocyanate-based polyurethane(NIPU)wood adhesive was produced from organosolv lignin,which is a bio-sourced raw material,available in large quantities and produced as a by-product of the paper *** formulation of this new lignin-based NIPU adhesive,which is presented,was chemically characterised by Matrix-Assisted laser Desorption Ionization Time of Flight(MALDI ToF)mass spectrometry and by Fourier Transform Infra-Red(FTIR)spectrometry *** oligomers formed were determined and showed that the three species involved in the NIPU adhesive preparation were formed by the co-reaction of the three reagents used:lignin,dimethyl carbonate,and hexamethylene *** and branched structures were both *** properties of the adhesive were determined using the Automated Bonding Evaluation System(ABES)and internal bond(IB)strength test of the laboratory particleboard bonded with *** adhesive has shown satisfactory mechanical properties after hot pressing at 230℃.Such a temperature is used industrially in the most modern particleboard factories,but since it is hardly feasible for more conventional wood bonding equipment,the reactivity of the NIPU adhesive was successfully increased with the addition of a small percentage of a silane coupling *** the addition of the silane,the proposed NIPU adhesive could also be used at a hot-pressing temperature lower than 200℃.

关键词： Organosolv lignin NIPU MALDI ToF FTIR ABES

丹参茉莉酸及丹参酮类成分对机械损伤诱导的响应分析

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中国中药杂志 2024年第15期49卷 3998-4006页

作者：刘琪虞慕瑶韩洋钱舒怡邰巴达拉胡郑汉黄璐琦南京中医药大学药学院江苏南京210023 中国中医科学院中药资源中心道地药材品质保障与资源持续利用全国重点实验室北京100700 北京中医药大学中药学院北京102488 上海交通大学农业与生物学院上海200240 内蒙古民族大学蒙医药学院内蒙古通辽028000

当植物遭受昆虫取食、极端天气及人为因素等导致的机械性损伤胁迫后,会迅速在转录及代谢水平上启动一系列的应答机制,引起植物内源激素及次生代谢物含量的变化。该研究以药用模式植物丹参为例,评估机械损伤对药用植物代谢的作用。运用qR... 详细信息

当植物遭受昆虫取食、极端天气及人为因素等导致的机械性损伤胁迫后,会迅速在转录及代谢水平上启动一系列的应答机制,引起植物内源激素及次生代谢物含量的变化。该研究以药用模式植物丹参为例,评估机械损伤对药用植物代谢的作用。运用qRT-PCR及LC-MS检测叶片损伤刺激下,胁迫响应的茉莉酸类物质(jasmonates,jas)和丹参酮类成分生物合成基因以及含量的变化情况,得出处理后不同时序叶片与根部在转录和代谢水平上的相关规律,从而探讨丹参对机械损伤胁迫的响应机制。结果显示,机械损伤诱导能够瞬时提高jas生物合成基因的表达,其中AOC与jaR在诱导后开始上升,在2 h达到最高,AOS与OPR3则在4 h达到最高,与之相应的OPDA、ja及ja-Ile的含量均在2 h达到最高。丹参酮生物合成中二萜合酶基因CPS1与KSL1均在2 h上升至最高,而后修饰CYP450s基因则均在4 h上升至最高,4种丹参酮的含量则均在8 h内呈现持续上升的趋势。该研究为揭示机械损伤对次生代谢积累的研究提供参考,为进一步了解机械损伤胁迫下jas在增强植物抗性、促进活性成分积累和提高药材品质方面的作用奠定基础。

关键词：丹参机械损伤胁迫响应茉莉酸丹参酮

Reply to comment by Durkin et *** “Using a modern analogue to interpret depositional position in ancient fluvial-tidal channels:Example from the McMurray Formation,Canada” by *** Croix,***,and ***

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Geoscience Frontiers 2020年第3期11卷 1087-1092页

作者： Andrew D.la Croix Shahin E.Dashtgard james A.MacEachern School of Science University of WaikatoHamilton3240New Zealand Applied Research in Ichnology and Sedimentology(ARISE)Group Department of Earth SciencesSimon Fraser UniversityBurnabyBCV5A 1S6Canada

*** We are pleased to have the opportunity to discuss our paper (la Croix et al.,2019) with Durkin et al.(2020).Their critique demonstrates the wide interest in the McMurray Formation held by both academic and industry geoscientists,especially given the economic importance of the stratigraphic ***,it highlights the various working interpretations for the unit’s paleoenvironmental setting and stratigraphic architecture;two highly contested scientific *** et al.

关键词： al. Canada fluvial

Anatomical characterization of central, apical and minimal corneal thickness

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International Journal of Ophthalmology(English edition) 2014年第4期7卷 668-672页

作者： Federico Saenz-Frances Martha Cecilia Bermúdez-Vallecilla lara Borrego-Sanz Luis jaez J osé Marìa Martinez-de-la-Casa laura Morales-Fernandez Enrique Santos-Bueso Julián Garcia-Sanchez Julián Garcia-Feijoo Department of Ophthalmology Hospital Clínico San CarlosUniversidad Complutense de Madrid Instituto de Tecnologìa del Conocimiento Universidad Complutense de Madrid

·AIM: To anatomically locate the points of minimum corneal thickness and central corneal thickness(pupil center) in relation to the corneal apex.·METHODS: Observational, cross-sectional study, 299 healthy volunteers. Thickness at the corneal apex(AT),minimum corneal thickness(MT) and corneal thickness at the pupil center(PT) were determined using the pentacam. Distances from the corneal apex to MT(MD)and PT(PD) were calculated and their quadrant position(taking the corneal apex as the reference) determined:point of minimum thickness(MC) and point of central thickness(PC) depending on the quadrant position. Two multivariate linear regression models were constructed to examine the influence of age, gender, power of the flattest and steepest corneal axes, position of the flattest axis, corneal volume(determined using the Pentacam)and PT on MD and PD. The effects of these variables on MC and PC were also determined in two multinomial regression models.·RESULTS: MT was located at a mean distance of 0.909 mm from the apex(79.4% in the inferior-temporal quadrant). PT was located at a mean distance of 0.156 mm from the apex. The linear regression model for MD indicated it was significantly influenced by corneal volume(B =-0.024; 95% CI:-0.043 to-0.004). No significant relations were identified in the linear regression model for PD or the multinomial logisticregressions for MC and PC.·CONCLUSION: MT was typically located at the inferiortemporal quadrant of the cornea and its distance to the corneal apex tended to decrease with the increment of corneal volume.

关键词： cornealthickness anatomy glaucoma