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Mapping global research trends: Nutrition associations with nonalcoholic fatty liver disease - a scopus bibliometric analysis

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World Journal of Gastroenterology 2024年第24期30卷 3106-3119页

作者： Muna shakhshir sa'ed H Zyoud Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Department of Public Health College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Information Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine

BACKGROUND several bibliometric analyses have been carried out to identify research hotspots and trends in nonalcoholic fatty liver disease(NAFLD)***,there are still significant knowledge gaps that must be filled to advance our understanding of and ability to treat *** To evaluate,through bibliometric and visual analysis,the current status of related research,related research frontiers,and the developmental trends in the field of diet and *** We retrieved publications about diet and NAFLD published between 1987 and 2022 from ***,we used VOsviewer 1.6.20 to perform bibliometric analysis and *** We found a total of 1905 studies,including 1637(85.93%)original articles and 195(10.24%)reviews,focused on the examination of NAFLD and its correlation with diet that were published between 1987 and *** the remaining five types of documents,38 were letters,notes,editorials,meeting minutes,or brief surveys,representing 1.99%of the total *** countries with the most publications on this topic were China(n=539;28.29%),followed by the United states(n=379;19.90%),Japan(n=133;6.98%),and south Korea(n=127;6.6%).According to the citation analysis,the retrieved papers were cited an average of 32.3 times and had an h-index of 106,with 61014 total *** two main clusters on the map included those related to:(1)Inflammation and oxidative stress;and(2)Dietary interventions for *** This was the first study to use data taken from scopus to visualize network mapping in a novel bibliometric analysis of studies focused on diet and *** 2017,the two domains that received the most attention were“dietary interventions for NAFL”’and“‘inflammation and oxidative stress implicated in NAFLD and its correlation with diet.”We believe that this study provides important information for academics,dietitians,and doctors,and that additional research on dietary interventions and NAFLD is warranted.

关键词： Dietary Nutrition Bibliometric Nonalcoholic fatty liver scopus VOsviewer

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Perspectives for delivery of therapeutics by extravasation of biodegradable microspheres in the brain

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Neural Regeneration Research 2024年第5期19卷 969-970页

作者： Anne-Eva van der Wijk ed VanBavel Amsterdam UMC location University of Amsterdam Department of Biomedical Engineering and PhysicsAmsterdamThe Netherlands Amsterdam Neuroscience Neurovascular Disorders ProgramAmsterdamThe Netherlands Amsterdam Cardiovascular sciences Microcirculation ProgramAmsterdamThe Netherlands

Development of therapeutics for brain diseases has remained challenging,in particular due to the difficulty of passing the blood-brain *** a result,the current arsenal of therapeutics targeting the brain is limited to small,lipid-soluble drugs and there is a lack of options for treating neuroblastomas,Alzheimer’s disease,and many other devastating *** the advances in strategies for crossing the blood-brain barrier such as the use of nanoparticles(Hersh et al.,2022;Duan et al.,2023),such delivery systems have not yet reached clinical ***,novel platforms for the transport of therapeutics across the blood-brain barrier remain highly *** specifically holds for large molecules such as monoclonal antibodies and recombinant proteins,as well as nucleotide-based therapeutics and cell *** efforts in this field are increasing exponentially,with thousands of publications in the last few years.

关键词： therapeutics holds spite

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Mapping the global research landscape on nonalcoholic fatty liver disease and insulin resistance:A visualization and bibliometric study

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World Journal of Hepatology 2024年第6期16卷 951-965页

作者： sa'ed H Zyoud Omar E Hegazi samer O Alalalmeh Muna shakhshir Faris Abushamma shadi Khilfeh samah W Al-Jabi Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine College of Pharmacy and Health sciences Ajman UniversityAjman 346United Arab Emirates Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Department of Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Urology An-Najah National University HospitalNablus 44839Palestine Department of Gastroenterology Hepatology and EndoscopyAn-Najah National University HospitalNablus 44839Palestine

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic *** it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and *** To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and *** This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the sciVerse scopus database from 1999 to *** search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and *** software was used to visualize research trends,collaborations,and key thematic *** analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited *** This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and *** search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)*** most productive countries were China(n=134;18.74%),the United states(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United states(n=48;6.71%),and the National Natural science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflamma

关键词： Nonalcoholic fatty liver disease Insulin resistance Bibliometric Visualization

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Operational guidance for aeration and flow augmentation for the Chicago Area Waterway system—A case study

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Water science and Engineering 2023年第4期16卷 345-358页

作者： Charles s.Melching Jennifer Wasik ed staudacher Thomas Minarik Melching Water solutions LLC GreenfieldWI 53221USA Metropolitan Water Reclamation District of Greater Chicago ChicagoIL 60611USA Metropolitan Water Reclamation District of Greater Chicago CiceroIL 60804USA

The Chicago Area Waterway system(CAWs)is a 133.9 km branching network of navigable waterways controlled by hydraulic structures,in which the majority of the flow is treated wastewater effluent and there are periods of substantial combined sewer *** CAWs comprises a network of effluent dominated *** stringent dissolved oxygen(DO)standards and a reduced flow augmentation allowance have been recently applied to the ***,a carefully calibrated and verified one-dimensional flow and water quality model was applied to the CAWs to determine emission-based real-time control guidelines for the operation of flow augmentation and aeration *** goal of these guidelines was to attain DO standards at least 95%of the ***“optimal”guidelines were tested for representative normal,dry,and wet *** finally proposed guidelines were found in the simulations to attain the 95%target for nearly all locations in the CAWs for the three test *** developed operational guidelines have been applied since 2018 and have shown improved attainment of the DO standards throughout the CAWs while at the same time achieving similar energy use at the aeration stations on the Calumet River system,greatly lowered energy use on the Chicago River system,and greatly lowered discretionary diversion from Lake Michigan,meeting the recently enacted lower amount of allowed annual discretionary *** case study indicates that emission-based real-time control developed from a well calibrated model holds potential to help many receiving water bodies achieve high attainment of water quality standards.

关键词： Water quality modeling Water quality management Real-time control stream aeration Flow augmentation Dissolved oxygen

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Hard life for sons in the nest?sex-dependent offspring mortality in Great Tits in urban and forest areas

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Avian Research 2024年第1期15卷 91-97页

作者： Nora Agh Henriett Anna Dalvári Krisztián szabó Ivett Pipoly András Liker HUN-REN-PE Evolutionary Ecology Research Group University of PannoniaH-8200VeszpremPf.1158.Hungary Behavioral Ecology Research Group Center for Natural SciencesUniversity of PannoniaH-8200Pf.1158.VeszpremHungary Molecular Ecology Research Group Department of EcologyUniversity of Veterinary Medicine BudapestH-1400Pf.2.BudapestHungary synlab Hungary Ltd. H-1211Weiss Manfr´ed Str.5-7BudapestHungary

sex-biased mortality can occur in birds during development,for example due to sexual differences in energy requirement and/or environmental sensitivity,or the effects of sex hormones or sex differences in the expression of mutations linked to sex *** extent of sex-bias in mortality may also be related to environmental conditions that influence offspring development and *** areas often provide poorer conditions for nestling development resulting in higher offspring mortality compared to natural areas,which may accelerate sex differences in offspring mortality in *** test this hypothesis,we examined the sex ratio of dead offspring in Great Tits(Parus major),using 427 samples of unhatched eggs and dead nestlings collected in two urban and two forest sites between 2013 and *** ratio of males in the whole sample of dead offspring(56.9%)was significantly higher than expected by an 1:1 ratio,and the strongest sex biases were detected in urban areas(57.6%males)and in young nestlings(s old,59.0%males).However,the sex ratios of dead offspring did not differ significantly among study sites and between offspring developmental stages.29.3%of unhatched eggs contained a visible embryo,and the proportion of embryo-containing unhatched eggs did not differ significantly between urban and forest study *** results suggest male-biased offspring mortality in Great Tits,and highlight the need of large datasets to detect subtle differences between habitats and developmental stages.

关键词： Great Tit Urbanization Nestling mortality sex related differences

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Loss to specialized Cardiology Follow-Up in Adults Living with Congenital Heart Disease

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Congenital Heart Disease 2024年第1期19卷 49-63页

作者： Cheryl Dickson Danielle Osborn David Baker Judith Fethney David s.Celermajer Rachael Cordina Department of Cardiology Royal Prince Alfred HospitalSydneyAustralia Department of Cardiothoracic surgery Westmead HospitalSydneyAustralia susan Wakil school of Nursing and Midwifery The University of SydneySydneyAustralia sydney Medical school The University of SydneySydneyAustralia

Background:Much has been written about the loss to follow-up in the transition between pediatric and adult Congenital Heart Disease(CHD)care *** less is understood about the loss to follow-up(LTF)after a successful *** is critical too,as patients lost to specialised care are more likely to experience mor-bidity and premature ***:To understand the prevalence and reasons for loss to follow-up(LTF)at a large Australian Adult Congenital Heart Disease(ACHD)***:Patients with moderate or highly complex CHD and gaps in care of>3 years(deﬁned as LTF)were identiﬁed from a comprehensive ACHD *** telephone interviews examined current care and barriers to clinic ***:Overall,407(22%)of ACHD patients(n=1842)were *** mean age at LTF was 31(sD 11.5)years and 54%were male;311(76%)were *** to adults seen regularly,lost patients were younger,with a greater socio-economic disadvantage,and had less complex CHD(ped 59 patients(14%).The top 3 responses for care absences were“feeling well”(61%),losing track of time(36%),and not needing fol-low-up care(25%).Conclusions:A large proportion of the ACHD population becomes lost to specialised cardiac care,even after a successful *** Australian study reports younger age,moderate complexity defects,and socio-economic disadvantage as predictive of loss to *** study highlights the need for novel approaches to patient-centered service delivery even beyond the age of transition and resources to maintain patient engagement within the ACHD service.

关键词： Loss to follow-up follow-up adult congenital heart disease lapse in care gaps in care care gaps care continuity ACHD predictors

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摇摆中的“摇摆州”与新移民

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环球财经 2024年第5期 122-123页

作者：丰君子艾德·霍尔(ed Hall)(图) 不详

1796年9月17日,美国首位总统乔治·华盛顿在当时的重要报纸《美国广告者日报》向全体美国人民发表了著名的公开告别信。这封公开信又被称为“华盛顿的告别演说”。信中,华盛顿除了谢绝连任总统的提议,还着重表达了自己对党派斗争与分立... 详细信息

1796年9月17日,美国首位总统乔治·华盛顿在当时的重要报纸《美国广告者日报》向全体美国人民发表了著名的公开告别信。这封公开信又被称为“华盛顿的告别演说”。信中,华盛顿除了谢绝连任总统的提议,还着重表达了自己对党派斗争与分立的看法。

关键词：乔治·华盛顿党派斗争公开信摇摆

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Global research on Clostridium difficile-associated diarrhoea:A visualized study

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World Journal of Gastroenterology 2022年第28期28卷 3720-3731页

作者： sa'ed H Zyoud Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Information Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine

BACKGROUND Clostridioides(Clostridium)difficile(***)is still the most common cause of healthcare-associated diarrhoea and is increasing in prevalence as a communityacquired *** addition,the emergence of antibiotic resistance in *** can increase the likelihood of the disease developing and/or *** To provide an up-to-date picture of the trends in publications related to *** infection,together with specific insights into hot-button issues in this *** Publications on *** infections in the field of microbiology between 2001 and 2020 were identified from the scopus database and Reference Citation *** indicators were determined,including the number and type of publications,countries,affiliations,funding agencies,journals and citation *** was used to determine research areas and hot-button issues by identifying recurring terms with a high relative occurrence in the title and *** A total of 8127 documents on‘***-associated diarrhoea’published between 2001 and 2020 were retrieved from the scopus *** the last decade,there has been a significant almost fourfold increase in the number of published papers on this *** United states was among the countries(44.11%)with the most publications,and the most involved institution was the University of Leeds in the United Kingdom(2.50%).Three clusters of research were identified and included‘illness spectrum and severity,as well as the signs,symptoms and clinical pathogenesis of ***’;‘laboratory diagnosis and characterization of ***’and‘risk factors for *** infection’.CONCLUsION This study contains the most up-to-date and comprehensive data ever compiled in this *** international research and cross-institutional collaborations are needed to address more global *** concerns and to benefit from greater sharing of expertise,which will result in higher quality or more effective

关键词： Clostridioides Clostridium difficile Bibliometric scopus VOsviewer Diarrhoea

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Research landscape on COVID-19 and liver dysfunction: A bibliometric analysis

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World Journal of Gastroenterology 2023年第27期29卷 4356-4367页

作者： sa'ed H Zyoud Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Information Center(PCDIC) College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Centre An-Najah National University HospitalNablus 44839Palestine

BACKGROUND The global spread of severe acute respiratory syndrome coronavirus 2,responsible for coronavirus disease 2019(COVID-19),poses a significant risk to public *** the respiratory issues initially associated with the condition,severe cases of COVID-19 can also lead to complications in other organs,including the *** with severe COVID-19 may exhibit various clinical signs of liver dysfunction,ranging from minor elevations in liver enzymes without symptoms to more serious cases of impaired liver *** damage is more commonly observed in patients with severe or critical forms of the *** To present the research landscape on COVID-19 and liver dysfunction while also offering valuable insights into the prominent areas of interest within this particular *** On 18 February 2023,scopus was utilised to conduct a comprehensive exploration of the relationship between COVID-19 and the liver *** investigation encompassed the period from 1 January 2020 to 31 December *** sources were meticulously examined and organised in a Microsoft Excel 2013 spreadsheet,categorised by journal,institution,funding agency,country and citation *** version 1.6.18 was employed to explore the prominent topics and knowledge network related to the *** There were 2336 publications on COVID-19 and liver dysfunction analysed in this study,of which 558 were published in 2020,891 in 2021 and 887 in *** from 111 different countries participated in the retrieved *** United states contributed the most studies,with 497 documents,representing 21.28%of the total,followed by China with 393 documents(16.82%)and Italy with 255 documents(10.92%).In the context of research related to COVID-19 and the liver,co-occurrence analysis identified three distinct clusters of topics:(1)‘COVID-19 vaccines in liver transplant recipients’;(2)‘liver function tests as a predictor of the severity and clinical outcom

关键词： COVID-19 Bibliometric scopus Vosviewer Liver

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synthesis and applications of lanthanoid complexes of pentadentate and hexadentate N_(5) and N_(6) macrocycles:A review

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Journal of Rare Earths 2024年第1期42卷 1-15,I0001页

作者： Julio Corredoira-Vázquez Cristina González-Barreira Paula Oreiro-Martínez Ana M.García-Deibe Jesús sanmartín-Matalobos Matilde Fondo Departamento de Química Inorganica Facultade de QuímicaUniversidade de Santiago de CompostelaCampus Vida15782Santiago de CompostelaSpain Phantom-g CICECO-Aveiro Institute of MaterialsDepartment of PhysicsUniversity of Aveiro3810-193AveiroPortugal Institute of Materials(iMATUs) Universidade de Santiago de Compostela15782Santiago de CompostelaSpain

In this paper,the lanthanoid complexes of N_(5) and N_(6) macrocycle ligands,without pendant arms or additional heteroatoms,are *** review covers the period from 2015 to the current date,since in 2014 schiff base macrocyclic ligands incorporating the pyridine moiety,and their complexes,were revised,and in 2015 the chemistry of pentaaza macrocycle ligands with rare earth metals was also *** and phthalocyanine ligands are not included in this review,which primarily focuses on complexes with schiff bases and amines without pendant arms or any additional donor other than *** synthetic methods,structural characterization,based on single X-ray crystal data,and properties of the lanthanoid complexes,with special attention to magneto-structural correlations,are presented herein.

关键词： Lanthanoid N_(5),N_(6)macrocycle Coordination chemistry Chirality Biological activity Molecule magnet

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