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Intravenous haloperidol for the treatment of intractable vomiting,cyclical vomiting,and gastroparesis

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World Journal of emergency Medicine 2021年第3期12卷 228-231页

作者： Brad e.Schwartz Karen Keller Baker Andrew J.Bleinberger Amina Lleshi Raul Cruz-Cano Department of emergency Medicine University of Maryland Capital Region HealthUM Prince George’s Hospital CenterCheverly 20785USA Ross University School of Medicine Bridgetown Bridgetown 11093Barbados Department of epidemiology and Biostatistics School of Public Health of the University of MarylandBaltimore 21201USA

Dear editor,The incidence of emergency department(ed)visits from gastroparesis and cannabinoid hyperemesis syndrome has increased by two folds over the past decade.[1-3]Roldan et al[4]reported that patients with these conditions often have prolonged ed stays and are likely to be hospitalized because of the danger of dehydration and challenges inherent in relieving *** analgesia is a particularly troublesome treatment modality;these conditions are often chronic with frequent recurrences,and repeated opiate therapy can cause opioid dependency and narcotic bowel syndrome.[5]Haloperidol(HP)and droperidol,members of the butyrophenone class,have potent antidopaminergic activity in the chemoreceptor trigger zone.[6,7]Intramuscular administration of HP is being used increasingly in the ed to treat nausea,vomiting secondary to gastroparesis,[6]intractable vomiting,[8]and cyclical vomiting.

关键词： vomiting gastro treatment

Germline MLH1 and MSH2 mutational spectrum including frequent large genomic aberrations in Hungarian hereditary non-polyposis colorectal cancer families:Implications for genetic testing

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World Journal of Gastroenterology 2007年第19期13卷 2727-2732页

作者： Janos Papp Marietta e Kovacs edith Olah Department of Molecular Genetics National Institute of Oncology Rath Gy. u. 7-9 H-1122 Budapest Hungary

AIM: To analyze the prevalence of germline MLH1 and MSH2 gene mutations and evaluate the clinical characteristics of Hungarian hereditary non-polyposis colorectal cancer (HNPCC) families. MeTHODS: Thirty-six kindreds were tested for mutations using conformation sensitive gel electrophoreses, direct sequencing and also screening for genomic rearrangements applying multiplex ligation-dependent probe amplifi cation (MLPA). ReSULTS: eighteen germline mutations (50%) were identifi ed, 9 in MLH1 and 9 in MSH2. Sixteen of these sequence alterations were considered pathogenic, the remaining two were non-conservative missense alterations occurring at highly conserved functional motifs. The majority of the defi nite pathogenic mutations (81%, 13/16) were found in families fulfilling the stringent Amsterdam Ⅰ/Ⅱ criteria, including three rearrangements revealed by MLPA (two in MSH2 and one in MLH1). However, in three out of sixteen HNPCC-suspected families (19%), a disease-causing alteration could be revealed. Furthermore, nine mutations described here are novel, and none of the sequence changes were found in more than one ***: Our study describes for the f irst time the prevalence and spectrum of germline mismatch repair gene mutations in Hungarian HNPCC and suspected-HNPCC families. The results presented here suggest that clinical selection criteria should be relaxed and detection of genomic rearrangements should be included in genetic screening in this population.

关键词： Germline mutation Hereditary non-polyposis colorectal cancer MLH1 MSH2 Rearrangement

Using technology in the classroomtiple intelligences/ 6th ed. 6th edition

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Influence of vitamin D on liver fibrosis in chronic hepatitis C: A systematic review and meta-analysis of the pooled clinical trials data

2005年

作者： Gary G.Bitter Melissa e.Pierson.

来源：畅想之星图书光盘版（南... 评论

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World Journal of Hepatology 2017年第5期9卷 278-287页

作者： Alia S Dadabhai Behnam Saberi Katie Lobner Russell T Shinohara Gerard e Mullin Division of Gastroenterology and Hepatology the Johns Hopkins University School of Medicine Department of Biostatistics and epide-miology Perelman School of Medicine University of Pennsylvania

AIM To investigate the relationship between vitamin D and liver fibrosis in hepatitis C-monoinfected or hepatitis C virus(HCV)-human immunodeficiency virus(HIV) coinfected patients. MeTHODS Pertinent studies were located by a library literature search in PubM ed/embase/Cochrane/Scopus/LILACS by two individual reviewers. Inclusion criteria:(1) studies with patients with HCV or co-infected HCV/HIV;(2) studies with patients ≥ 18 years old;(3) studies that evaluated liver fibrosis stage, only based on liver biopsy; and(4) studies that reported serum or plasma 25(OH)D levels. Studies that included pediatric patients, other etiologies of liver disease, or did not use liver biopsy for fibrosis evaluation, or studies with inadequate data were excluded. estimated measures of association reported in the literature, as well as corresponding measures of uncertainty, were recorded and corresponding odds ratios with 95%CI were included in a meta-analysis. ReSULTS The pooled data of this systematic review showed that 9 of the 12 studies correlated advanced liver disease defined as a Metavir value of F3/4 with 25(OH) D level insufficiency. The meta-analysis indicated a significant association across *** Low vitamin D status is common in chronic Hepatitis C patients and is associated with advanced liver fibrosis.

关键词： Vitamin D Liver fibrosis Hepatitis C virus Chronic hepatitis C

K Shell Fluorescence Parameters by Impact of 5.96 keV Photons on Ti and Its Compounds

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光谱学与光谱分析 2016年第12期36卷 4125-4129页

作者： O.K.KOeKSAL G.APAYDIN e.CeNGZ Department of Physics Faculty of Sciences Karadeniz Technical University Trabzon 61080 Turkey

K shell fluorescence parameters of pure Ti and some of its compounds have been determined experimentally using an Ultra-LeGe detector with resolution 150 eV at *** samples were excited 5.96 keV photons emitted from a ^(55) Fe radioisotope source with 50 mCi *** experimental values of the K shell fluorescence parameters have been compared with the experimental and theoretical values available in the literature for pure Ti.

关键词： K Shell fluorescence parameters 55Fe radioactive source ed-XRF Titanium

Renal biopsy practice:What is the gold standard?

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World Journal of Nephrology 2014年第4期3卷 287-294页

作者： Soumeya Brachemi Guillaume Bollée Division of Nephrology and Research Center of the Centre Hospitalier de l’Université de Montréal and Université de Montréal

Renal biopsy （RB） is useful for diagnosis and therapy guidance of renal diseases but incurs a risk of bleeding complications of variable severity, from transitory hae-maturia or asymptomatic hematoma to life-threatening hemorrhage. Several risk factors for complications after RB have been identifed, including high blood pressure, age, decreased renal function, obesity, anemia, low platelet count and hemostasis disorders. These should be carefully assessed and, whenever possible, correct-ed before the procedure. The incidence of serious com-plications has become low with the use of automated biopsy devices and ultrasound guidance, which is cur-rently the “gold standard” procedure for percutaneous RB. An outpatient biopsy may be considered in a care-fully selected population with no risk factor for bleed-ing. However, controversies persist on the duration of observation after biopsy, especially for native kidney biopsy. Transjugular RB and laparoscopic RB represent reliable alternatives to conventional percutaneous bi-opsy in patients at high risk of bleeding, although some factors limit their use. This aim of this review is to sum-marize the issues of complications after RB, assessment of hemorrhagic risk factors, optimal biopsy procedure and strategies aimed to minimize the risk of bleeding.

关键词： Renal biopsy Bleeding Complications Procedure

GeOLOGIA DeLLA ZONA AD OVeST DeL FIUMe CHIeSe TRA DARZO e CONDINO(Trento)

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Natural Disaster Reduction in China 1989年第1期 77-85页

作者： GIOVANNI BORGOGNA e PAOLO PeRFUMI

Nell’area studiata sono riconoscibili tre differenti facies della Formazione di Collio (Per-miano inferiore): una vulcanica costituita da lave riolitiche e dacitiche, tufi cristallini e litici, ignimbriti;due sedimentarie che comprendono conglomerati e arenarie l’una, sihiti e argilliti l’altra. L’assetto geolo-gico evidenzia l’esistenza di due zone in subsidenza differenziale, comunicanti per mezzo di scarpatedi faglia. La zona nord-orientale è caratterizzata dalla prevalenza di rocce vulcaniche (《Porfidi quarziferiindistinti》 degli Autori precedenti); quella sud-occidentale è invece colmata dai depositi fluviali provenien-ti dallo smantellamento penecontemporaneo della prima ed è suturata dagli espandimenti lavici del ***. All’attività vulcanica ed esplosiva fa seguito un periodo geologico più tranquillo: su tutta l’areasi impostano bacini lacustri entro i quali si depositano arenarie fini, siltiti e *** of the region west of the River Chiese between Darzo and Condino (Trento- Northern Italy). Three different facies have been recognized in the area: a volcanic one which includesrhyolithic and lacitic lavas, crystalline and lithic tufts and ignimbrites; two sedimentary ones, the firstof which is formed by conglomerates and sandstones, the second by siltites and mudstones. The geologicalorder shows two areas of different subsidence, which communicate through fault escarpements. In thenorth-eastern one the volcanic rocks (《Porfidi quarziferi indistinti》 of the previous Authors) *** south-western area is filled with fluvial deposits deriving from the dismanthing of the north-easternpart. The top originated from the volcanic spreading of Monte Macaone. The volcanic and explosiveactivities were followed by a period of relative geological stability. All the region was later covered withlake basins containing sandstones, siltstones and mudstones.

关键词：吸泥

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电子签名与笔迹认证技术研究

计算机工程与应用 2003年第2期39卷 68-69,93页

作者：梁建武施荣华中南大学铁道校区现代教育技术中心长沙410075

论文介绍在网上任何终端对所有文档实现电子签名,并能保证签名的唯一性,文档的完整性,内容的安全性。同时对人的手写签名生物特征作为身份认证和文档加密的有效性和不可否认性进行研究并具体实现。

关键词：电子签名笔迹认证身份认证加密信息安全办公自动化计算机

Internetworking with TCP IP Vol.1: Principles, Protocols, and Architecture (4th edition) 4th ed.

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