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Mapping the global research landscape on nonalcoholic fatty liver disease and insulin resistance:A visualization and bibliometric study

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World Journal of Hepatology 2024年第6期16卷 951-965页

作者： Sa'ed H Zyoud Omar e Hegazi Samer O Alalalmeh Muna Shakhshir Faris Abushamma Shadi Khilfeh Samah W Al-Jabi Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine College of Pharmacy and Health Sciences Ajman UniversityAjman 346United Arab Emirates Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Department of Medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Urology An-Najah National University HospitalNablus 44839Palestine Department of Gastroenterology Hepatology and EndoscopyAn-Najah National University HospitalNablus 44839Palestine

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic *** it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and *** To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and *** This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the SciVerse Scopus database from 1999 to *** search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and *** software was used to visualize research trends,collaborations,and key thematic *** analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited *** This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and *** search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)*** most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical endocrinology and Metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflamma

关键词： Nonalcoholic fatty liver disease Insulin resistance Bibliometric Visualization

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Current devices,outcomes,and pain management considerations in penile implant surgery:an updated review of the literature

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Asian Journal of Andrology 2024年第4期26卷 335-343页

作者： Nirupama Ancha Maya eldin Tarah Woodle Sofia Gereta Krishna Hariprasad Imani Butler e Charles Osterberg III Department of Surgery and Perioperative Care University of Texas at Austin Dell Medical SchoolAustinTX 78712USA Department of Urology Brooke Army Medical CenterSan AntonioTX 78234USA Department of Molecular Biosciences The University of Texas at AustinAustinTX 78712USA.

Penile prosthesis surgery is a definitive treatment for erectile dysfunction(ed).The two categories of penile prosthesis are endorsed by professional guidelines,inflatable penile prosthesis(IPP)and malleable penile prosthesis(MPP).each modality of penile prosthesis offers distinct advantages and incorporates specific design features,allowing for personalized device selection that aligns with individual needs and *** the overall complication rate of penile implant surgery remains low,surgeons should maintain a high index of suspicion for complications in the perioperative time *** analgesic regimens including nerve blocks and narcotic-free pathways should be administered to manage perioperative ***,the high patient satisfaction after penile prosthesis surgery underscores the success of this ed treatment option.

关键词： erectile dysfunction penile implant penile prosthesis

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Global standard names for the Lowermost Cambrian Series and Stage

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episodes 2007年第4期30卷 287-289页

作者： ed Landing Shanchi Peng Loren e. Babcock Gerd Geyer Malgorzata Moczydlowska- Vidal New York State Museum Madison Avenue Albany New York 12230 USA. State Key Laboratory of Stratigraphy and Palaeobiology Nanjing Institute of Geology and Palaeontology 39 East Beijing Road Nanjing 210008 China School of earth Sciences The Ohio State University Columbus Ohio 43210 USA Institut für Palaiontologie Bayerische Julius-Maximillians-Universitat Pleicherwall 1 D97070 Würzburg Germany Department of earth Sciences Uppsala University Norbyvaigen 22 Sweden.

The GSSP marking the base of the Cambrian System was ratified by the lUGS in 1992. Ratification of the GSSP point at the base of the Trichophycus pedum Ichnozone in the Fortune Head section, eastern Newfoundland, Canada, automatically defined the conterminant base of the lowermost series and stage of the Cambrian although names for those subdivisions were not proposed at the time of the decision. In 2007, the lUGS ratified the names Terreneuvian Series and Fortunian Stage for these previously unnamed chronostratigraphic subdivisions. The Terreneuvian Series replaces the provisional name ＂Series 1,＂ and the Fortunian Stage replaces the provisional name ＂Stage 1,＂ of the Cambrian System.

关键词：寒武纪全球标准地质学测量方法

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Medical management of ischemic stuttering priapism： a ：ontemporary review of the literature

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Asian Journal of Andrology 2012年第1期14卷 156-163,180页

作者： Helen R Levey omer Kutlu Trinity J Bivalacqua The Arthur Smith Institute for Urology North Shore- Long Island Jewish Health System New Hyde Park NY 11010 USA The James Buchanan Brady Urological Institute Department of Urology Johns Hopkins Hospital Baltimore MD 21287 USA

Priapism is defined as a prolonged and persistent erection of the penis without sexual stimulation. This is a poorly understood disease process with little information on the pathophysiology of this erectile disorder. Complications from this disorder are devastating due to the irreversible erectile damage and resultant erectile dysfunction （ed）. Stuttering priapism, though relatively rare, affects a high prevalence of men with sickle-cell disease （SCD） and presents a challenging problem with guidelines for treatment lacking or resulting in permanent ed. The mechanisms involved in the development of priapism in this cohort are poorly characterized; therefore, medical management of priapism represents a therapeutic challenge to urologists. Additional research is warranted, so we can effectively target treatments for these patients with prevention as the goal. This review gives an introduction to stuttering priapism and its clinical significance, specifically with regards to the patient with SCD. Additionally, the proposed mechanisms behind its pathophysiology and a summary of the current and future targets for medical management are discussed.

关键词： erectile dysfunction ischemic priapism medical management recurrent priapism sickle cell disease stuttering priapism therapy treatment

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Simply-typed Underdeterminism

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Journal of Computer Science & Technology 1998年第6期13卷 491-508页

作者： ewen Denney(LFCS, Department of Computer Science, Universitg of edinburphKings Buildings, edinburph eH9 3JZ, Scotland)e-mail: ewd@dcs.ed.ac.uk LFCS Department of Computer Science University of Edinburgh Edinburgh Scotland

An extension of the simply-typed lambda calculus with constructs for expressing a notion calledunderdeterminism is studied. This allows us to interpret notions of stub and skeleton used in top-down program development. We axiomatise a simple notion of program refinement, and give a semantics, for which the calculus is proved sound and complete.

关键词： Refinement lambda-calculus Henkin models

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Autophagy, apoptosis and organelle features during cell exposure to cadmiumč

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BIOCeLL 2013年第2期37卷 45-54页

作者： CRISTIANe DOS SANTOS VeRGILIO edÉSIO JOSÉTeNÓRIO De MeLO Universidade estadual do Norte Fluminense Centro de Biociências e BiotecnologiaLaboratório de Biologia Celular e TecidualCampos dos GoytacazesRJBrasil28013-602.

Cadmium(Cd)induces several effects in different tissues,but our knowledge of the toxic effects on organelles is insuffi *** observe the progression of Cd effects on organelle structure and function,HuH-7 cells(human hepatic carcinoma cell line)were exposed to CdCl2 in increasing concentrations(1μM–20μM)and exposure times(2 h–24 h).During Cd treatment,the cells exhibited a progressive decrease in viability that was both time-and *** treated cells displayed progressive morphological changes that included cytoplasm retraction and nuclear condensation preceding a total loss of cell *** with 10μM for 12 h led to irreversible *** these drastic and irreparable damages,treated cells(5μM for 12 h)presented a progressive loss of mitochondrial function and cytoplasm acidifi cation as well as dysfunction and disorganization of microfi laments and endoplasmic *** damages led to the induction of apoptotic events and an increase in autophagic bodies in the *** results revealed that Cd affects multiple intra-cellular targets that induce alterations in the mitochondria,cytoskeleton,endoplasmic reticulum and acidic compartments,ultimately culminating in cell death via apoptotic and autophagic pathways.

关键词： Cd cell death hepatocyte HuH-7 cells mitochondria

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Light weighting opportunities and material choice for commercial vehicle frame structures from a design point of view

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Advances in Manufacturing 2015年第1期3卷 19-26页

作者： Peter Seyfried ed Juarez Mendes Taiss Alexandre Costa Calijorne Fei-Peng Li Qi-Feng Song Hamburg University of Applied Sciences Hamburg Germany Companhia Brasileira de Metalurgia e Mineracao Villa NovaMGBrazil Caltra Projetos & Consultoria Belo HorizonteMGBrazil Dongfeng Commercial Vehicle Technology Center FAW Technology Center

This paper focuses on an estimation of light weighting opportunities for the frame structure of com- mercial road vehicles. This estimation is based on simpli- fied static load cases which play a predominant role for the dimensioning of a frame structure and therefore these simplifications are not putting the general validity of the conclusions into question. A comparison of different ma- terials under this scenario shows that light metals do not show any weight reduction advantage in comparison to steel while a material-independent topology optimization has more weight reduction potential for the frame structure than a simple change of materials. Considering the con- straints of part complexity which is directly linked with production and assembly cost, the ladder frame structure has become the current state of the art design. Thus the paper also puts a spotlight on basic rules of node design and vertical load induction in order to keep the weight of such a design as low as possible. Practical examples from manufacturers show that the weight of a commercial vehicle could be reduced by 10%, and main parts of the frame structure could be reduced by 30% using high strength steel in combination with innovative production methods like roll forming.

关键词： Ladder frame . Light weighting.Commercialvehicle .Node design - High strength steel - Profilesection . Vertical bending .Topology optimization

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团体咨询的策略与方法

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丛书名：心理学丛书:心理咨询与治疗系列

2000年

作者：（美）ed e.Jacobs等洪炜等译

本书论述了团体咨询的多个要素，提供了丰富的、富有洞察力的例证，并说明每种技巧在塑造有效的工作群的过程中是如何被广泛运用的。

ISBN: (数字)7501927146

ISBN: (纸本)7501927146

本书论述了团体咨询的多个要素，提供了丰富的、富有洞察力的例证，并说明每种技巧在塑造有效的工作群的过程中是如何被广泛运用的。

关键词：团体学科:咨询心理学咨询心理学

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TCP/IP使用详解

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丛书名：特版精品系列

1999年

作者：（美）（e.泰勒）ed Taylor 王虎等译

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Flexible mating tactics and associated reproductive effort during the rutting season in male reindeer （Rangifer tarandus, L. 1758）

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Current Zoology 2015年第5期61卷 802-810页

作者： eliana PINTUS Stefania UCCHedDU Knut H. RФed Javier Perez GONZALeZ Juan CARRANZA Mauri NIeMINeN Фystein HOLAND Department of Veterinary Sciences Faculty of Agrobiology Food and Natural Resources Czech University of Life Sciences Kamycka 129 165 21 Prague 6 - Suchdol Czech Republic Ungulate Research Unit Game and Fish Research Center University of Cordoba 14071 Cordoba Spain Department of Basic Sciences and Aquatic Medicine Norwegian University of Life Sciences EO. Box 8146 Dep. N-0033 Oslo Norway Guarderia Rural Mancomunidad de Municipios Centro (MIMC) 06810 Calamonte Spain Finnish Game and Fisheries Research Institute Reindeer Research Station 99910 Kaamanen Finland Department of Animal and Aquacultural Sciences Norwegian University of Life Sciences RO. Box 5003 N-1432 As Norway

Polygynous males can change their mating tactics across their lifetime, but information is scarce on the flexibility of this trait within a given season and the relative costs and benefits of using different tactics. Here, we monitored individually marked male reindeer Rangifer tarandus and classified their mating tactics as harem-defense, sneaking, or mixed. The costs of the male reproductive effort were assessed using both direct （i.e. percentage of body mass lost） and indirect measures （i.e. activity patterns such as feeding, standing, and walking）, while mating group size and reproductive success were recorded as mating ef- fort benefits. Our results show that reindeer males may switch between the harem-defense and sneaking tactics throughout the same breeding season, providing further support to the notion that reproductive tactics are flexible in ungulates. The costs and benefits of male mating effort vary according to the mating tactic, reaching the highest values in harem-holders and the lowest values in sneaking males. Moreover, males who switched between the sneaking tactic and the harem-defence tactic tended to achieve higher mating success than males who consistently used the least costly tactic. Indeed, all harem-holders successfully sired offspring, whereas only two out of three mixed-tactic males sired one calf, and sneaking males did not sire any calves. In conclusion, our results show that reindeer males can modulate their mating efforts during the same breeding season by switching between the most costly harem-defense tactic and the least costly sneaking tactic, suggesting individual solutions to the balance between reproductive effort and mating opportunities [Current Zoology 61 （5）： 802-810, 2015].

关键词： Alternative mating tactics Intraspecific variation Phenotypic flexibility Polygynous ungulate Sexual behaviour

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