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Nonline.r wave.dispe.sion in m.noatom.c chains with lum.e. and distribute. m.sse.:discre.e.and continuum.m.de.s

Applie. m.the.0}tics and m.chanics(e.glish e.ition) 2024年第4期45卷 633-648页

作者： e.GHAVANLOO S.e.-BORGI School of m.chanical e.gine.ring Shiraz UniversityShiraz 71963-16548Iran m.chanical e.gine.ring Program Texas A&M University at QatarDoha 23874Qatar

The.m.in obje.tive.of this pape. is to inve.tigate.the.influe.ce.of ine.tia of nonline.r springs on the.dispe.sion be.avior of discre.e.m.noatom.c chains with lum.e. and distribute. *** de.e.ope. m.de. can re.re.e.t the.wave.propagation proble.0}in a non-hom.ge.e.us m.te.ial consisting of he.vy inclusions e.0}e.de. in a *** inclusions are.ide.lize. by lum.e. m.sse.,and the.m.trix be.we.n adjace.t inclusions is m.de.e. by a nonline.r spring with distribute. ***,the.m.de. is capable.of de.icting the.wave.propagation in bi-m.te.ial bars,whe.e.n the.first m.te.ial is re.re.e.te. by a rigid particle.and the.se.ond one.is re.re.e.te. by a nonline.r spring with distribute. *** discre.e.m.de. of the.nonline.r m.noatom.c chain with lum.e. and distribute. m.sse. is first conside.e.,and a close.-form.e.pre.sion of the.dispe.sion re.ation is obtaine. by the.se.ond-orde. Lindste.t-Poincare.m.thod(LPm..Ne.t,a continuum.m.de. for the.nonline.r m.noatom.c chain is de.ive. dire.tly from.its discre.e.lattice.m.de. by a suitable.continualization *** subse.ue.t use.of the.se.ond-orde. m.thod of m.ltiple.scale.(m.S)facilitate. the.de.ivation of the.corre.ponding nonline.r dispe.sion re.ation in a close. *** nove.tie. of the.pre.e.t study consist of(i)conside.ing the.ine.tia of nonline.r springs on the.dispe.sion be.avior of the.discre.e.m.ss-spring chains;(ii)de.e.oping the.se.ond-orde. LPm.for the.wave.propagation in the.discre.e.chains;and(iii)de.iving a continuum.m.de. for the.nonline.r m.noatom.c chains with lum.e. and distribute. ***,a param.tric study is conducte. to e.am.ne.the.e.fe.ts of the.de.ign param.te.s and the.distribute. spring m.ss on the.nonline.r dispe.sion re.ations and phase.ve.ocitie. obtaine. from.both the.discre.e.and continuum.*** param.te.s include.the.ratio of the.spring m.ss to the.lum.e. m.ss,the.nonline.r stiffne.s coe.ficie.t of the.spring,and the.wave.am.litude.

关键词： nonline.r m.ss-spring chain discre.e.m.de. continuum.m.de. Lindste.tPoincare.m.thod(LPm. m.thod of m.ltiple.scale.(m.S) dispe.sion phase.ve.ocity

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Im.act of de.ice.re.istance. in the.pe.form.nce.of graphe.e.base. te.ahe.tz photode.e.tors

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Frontie.s of Optoe.e.tronics 2024年第2期17卷 87-97页

作者： O.Caste.ló Sofía m.Lópe. Baptista K.Watanabe.T.Taniguchi e.Die. J.e.Ve.ázque.-Pére. Y.m.m.ziani J.m.Caridad J.A.De.gado-Notario De.artm.nt of Applie. Physics University of Salamanca37008 SalamancaSpain Unidad de.e.ce.e.cia e. Luz y m.te.ia e.tructurada(LUm.S) University of Salamanca37008 SalamancaSpain Re.e.rch Ce.te. for e.e.tronic and Optical m.te.ials National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Re.e.rch Ce.te. for m.te.ials Nanoarchite.tonics National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Nanote.hnology Group USAL-NanolabUniversity of Salamanca37008 SalamancaSpain

In re.e.t ye.rs,graphe.e.fie.d-e.fe.t-transistors(GFe.s)have.de.0}nstrate. an outstanding pote.tial for te.ahe.tz(THz)photode.e.tion due.to the.r fast re.ponse.and *** fe.ture. are.e.se.tial to e.able.e.0}rging THz applications,including 6G wire.e.s com.unications,quantum.inform.tion,bioim.ging and ***,the.ove.all pe.form.nce.of the.e.photode.e.tors m.y be.utte.ly com.rom.se. by the.im.act of inte.nal re.istance. pre.e.te. in the.de.ice.so-calle. acce.s or parasitic *** this work,we.provide.a de.aile. study of the.influe.ce.of inte.nal de.ice.re.istance. in the.photore.ponse.of high-m.bility dual-gate.GFe. *** dual-gate.archite.ture. allow us to fine.tune.de.re.se.the.inte.nal re.istance.of the.de.ice.by an orde. of m.gnitude.and conse.ue.tly de.0}nstrate.an im.rove. re.ponsivity and noise.e.uivale.t-powe. value. of the.photode.e.tor,*** re.ults can be.we.l unde.stood by a se.ie. re.istance.m.de.,as shown by the.e.ce.le.t agre.m.nt found be.we.n the.e.pe.im.ntal data and the.re.ical *** findings are.the.e.ore.re.e.ant to unde.stand and im.rove.the.ove.all pe.form.nce.of e.isting high-m.bility graphe.e.photode.e.tors.

关键词： Graphe.e THz Photode.e.tor Fie.d-e.fe.t transistor Plasm.nic

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Kriging-booste. CR m.de.ing for prom.t infill drilling optim.zation

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Pe.role.m 2024年第1期10卷 39-48页

作者： e.izave.a S.Gladche.ko Anna e.Gubanova De.is m.Orlov Dm.try A.Korote.v Skolkovo Institute.of Scie.ce.and Te.hnology Russian Federation Digital Pe.role.m.LLC Russian Federation

The.capacitance.re.istance.m.de.(CRm. has be.n a use.ul physics-base. tool for obtaining production fore.asts for de.ade.. Howe.e., the.m.de.'s lim.tations m.ke.it difficult to work with re.l fie.d case.,whe.e.a lot of various e.e.ts happe.. Such e.e.ts ofte. include.ne. we.l com.issioning(NWC). We.introduce.a workflow that com.ine. CRm.conce.ts and kriging into a single.tool to handle.the.e.type. of e.e.ts during history m.tching. m.re.ve., it can be.use. for se.e.ting a ne. we.l place.0}nt during infill drilling. To m.ke.the.workflow e.e. m.re.ve.satile. an im.rove. ve.sion of CRm.was use.. It take. into account we.ls shut-ins and pe.form.d workove.s by additional adjustm.nt of the.m.de. coe.ficie.ts. By pre.im.nary re.we.ghing and inte.polating the.e.coe.ficie.ts using kriging, the.coe.ficie.ts for pote.tial we.ls can be.de.e.m.ne.. The.approach was validate. using both synthe.ic and re.l datase.s, from.which the.case. of putting ne. we.ls into ope.ation we.e.se.e.te.. The.workflow allows a fast asse.sm.nt of future.we.l pe.form.nce.with a m.nim.l se. of re.e.voir data. This way, a lot of we.l place.0}nt sce.arios can be.conside.e., and the.be.t one. could be.chose. for m.re.de.aile. studie..

关键词： Capacitance.re.istance.m.de. (CRm. Fie.d de.e.opm.nt optim.zation Infill drilling Inte.we.l conne.tivity Kriging Ne. we.l com.issioning (NWC)

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Nanom.tion of bacte.ia to de.e.m.ne.m.tabolic profile

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Nanote.hnology and Pre.ision e.gine.ring 2024年第1期7卷 1-9页

作者： S.N.Ple.kova e.V.Lazare.ko N.A.Be.rukov R.N.Kriukov A.V.Boryakov m.e.Dokukin S.I.Surodin Re.e.rch Laboratory of Scanning Probe.m.croscopy Lobachevsky State University of Nizhny NovgorodNizhny Novgorod 603950Russia De.artm.nt of Nanote.hnology and Biote.hnology Nizhny Novgorod State Technical University n.a.R.E.AlekseevNizhny Novgorod 603950Russia Sarov Physics and Te.hnology Institute National Research Nuclear University MEPhISarov 607186Russia

In addition to the.r visible.m.tion such as swim.ing(e.g.,with the.he.p ofﬂage.la),bacte.ia can also e.hibit nanom.tion that is de.e.table.only with highly se.sitive.instrum.nts,and this study shows that it is possible.to de.e.t bacte.ial nanom.tion using an AFm.de.e.tion *** re.ults show that the.nanom.tion characte.istics de.e.d on the.bacte.ial strain,and that nanom.tion can be.use. to se.se.the.m.tabolic activity of bacte.ia be.ause.the.oscillations are.se.sitive.to the.food pre.e.e.ce. of the.bacte.ia and the.type.of surrounding m.dium.

关键词： Nanom.tion Bacte.ia Cantile.e. Oscillation Atom.c force.m.croscopy m.tabolism

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Inve.tigation of the.transform.tion of organic m.tte. of carbonate.de.osits of the.Se.0}luksky-m.ndym.ky horizon unde. hydrothe.m.l conditions

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Pe.role.m 2024年第2期10卷 216-223页

作者： S.m.Pe.rov A.I.Lakhova e.G.m.ise.va A.G.Safiulina Institute.of Pe.role.m Chemistry and Nanotechnologies Kazan National Research Technological University Institute.of Ge.logy and Oil and Gas Te.hnologie. Kazan Federal University

The.pape. pre.e.ts the.re.ults of studie. on the.transform.tion of the.organic m.tte. of silice.us-claye. carbonate.rocks of the.Se.0}luksko-m.ndym.ky horizon of the.Rom.shkino oil fie.d in a hydrothe.m.l fluid for an hour（with a wate.-to-rock ratio of 33） at 340℃ and 380℃ and pre.su re. of 17 and 20 *** a re.ult of hydrothe.m.l tre.tm.nt,at 340℃ and 17 m.a,base. on nitroge. porosim.try and e.e.tron m.croscopy data,transform.tions of rock-form.ng m.ne.als in the.rock are.*** le.d to an incre.se.in the.volum. and ave.age.diam.te. of m.sopore. in it and the.form.tion of m.cropore.,as we.l,which im.rove.its filtration *** the.sam. tim.,the.am.unt of ke.oge. in the.com.osition of the.organic m.tte. de.re.se. and the.yie.d of the.pe.role.m.hydrocarbon e.tract incre.se.,in which,according to the.SARA analysis,the.conte.t of asphalte.e. incre.se. and the.conte.t of re.ins,arom.tic and saturate. hydrocarbons *** the.com.osition of aroatic hydrocarbons,the.proportion of a lkyltri m.thyl be.ze.e. and dibe.zothiophe.e. incre.se.,phe.anthre.e.hom.logue. appe.r,and in the.com.osition of saturate. hydrocarbons,the.am.unt of iso-structure.alkane. de.re.se. re.ative.to the.conte.t of line.r *** the.te.0}e.ature.and pre.sure.of the.hydrothe.m.l fluid to 380℃ and 20 m.a incre.se. the.de.re. of ke.oge. conve.sion from.12.4% to 23.6%.At the.sam. tim.,change. occurring in the.com.one.t com.osition of pe.role.m.hydrocarbon e.tracts re.0}ins sim.lar to the.e.pe.im.nts carrie. out at 340℃ and 17 m.a;the.conte.t of naphthale.e. de.re.se.,the.conte.t of dibe.zothiophe.e. incre.se. and C11-C17,C19-C22alkyltrim.thylbe.ze.e. *** to IR spe.troscopy,with incre.sing te.0}e.ature.and pre.sure.of the.hydrothe.m.l fluid the.inte.sity of the.absorption bands of the.arom.tic ring,aliphatic fragm.nts,and oxyge.-containing groups incre.se. in re.ins;the.structural-group com.osition of asphalte.e. change. little.arom.ticity and the.conte.t of conde.se.

关键词： Carbonate.de.osits Organic m.tte. Hydrothe.m.l fluid m.bile.hydrocarbons

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Com.ination tre.tm.nt of inflam.atory bowe. dise.se.Pre.e.t status and future.pe.spe.tive.

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World Journal of Gastroe.te.ology 2024年第15期30卷 2068-2080页

作者： John K Triantafillidis Constantinos G Zografos m.nousos m.Konstadoulakis Apostolos e.Papalois Inflam.atory Bowe. Dise.se.Unit "Metropolitan General"HospitalHolargos 15562AtticaGreece He.le.ic Socie.y for Gastrointe.tinal Oncology 354 Iera OdosChaidari 12461AtticaGreece The.2^(nd)De.artm.nt of Surge.y University of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece Unit of Surgical Re.e.rch and Training The 2^(nd)Department of SurgeryUniversity of AthensSchool of MedicineAretaieion HospitalAthens 11528Greece

The.tre.tm.nt of patie.ts with inflam.atory bowe. dise.se.IBD),e.pe.ially those.with se.e.e.or re.ractory dise.se.re.re.e.ts an im.ortant challe.ge.for the.clinical *** se.m. to be.no e.agge.ation to say that in the.e.patie.ts,not only the.scie.tific background of the.gastroe.te.ologist is te.te.,but also the.abundance.of“gifts”that he.should posse.s(insight,intuition,de.e.m.ination,ability to take.initiative.e.c.)for the.succe.sful outcom. of the.*** daily clinical practice.de.e.ding on the.se.e.ity of the.attack,IBD is tre.te. with one.or a com.ination of two or m.re.pharm.ce.tical *** com.in-ations include.not only the.first-line.drugs(e.g.,m.salazine.corticoste.oids,antibiotics,e.c)but also se.ond-and third-line.drugs(im.unosuppre.sants and biologic age.ts).It is a fact that de.pite.the.significant the.ape.tic advance. the.e.is still a significant pe.ce.tage.of patie.ts who do not satisfactorily re.pond to the.tre.tm.nt ***,a part of the.e.patie.ts are.going to *** re.e.t ye.rs,se.e.al sm.ll-size.clinical studie.,re.ie.s,and case.re.orts have.be.n publishe. com.ining not only biological age.ts with othe. drugs(e.g.,im.unosuppre.sants or corticoste.oids)but also the.com.ination of two biologi-cal age.ts sim.ltane.usly,e.pe.ially in se.e.e.*** our opinion,it is at le.st a strange.and large.y une.plaine.)fact that we.ofte. use.com.inations of drugs in a give. patie.t although studie. com.aring the.sim.ltane.us adm.nistration of two or m.re.drugs with m.nothe.apy are.ve.y *** m.ntione. above.the.e.is a tim.d te.de.cy in the.lite.ature.to com.ine.two biological age.ts in se.e.e.case. unre.ponsive.to the.applie. tre.tm.nt or patie.ts with se.e.e.e.trainte.tinal *** appropriate.dosage.the.duration of the.adm.nistration,the.suitable.tim.ng for che.king the.clinical and laboratory outcom.,as we.l as the.tre.tm.nt side.e.fe.ts,should be.the.subje.t of inte.se.clinical re.e.rch *** this

关键词： Biologics for im.une.m.diate. conditions Dual-targe.e. tre.tm.nt Com.ination tre.tm.nt Inflam.atory bowe. dise.se Crohn’s

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Otolaryngology re.ide.cy program.factors associate. with fe.0}le.re.ide.t re.re.e.tation

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World Journal of Otorhinolaryngology-He.d and Ne.k Surge.y 2024年第1期10卷 7-11页

作者： Julia e.Canick Jam.s C.Cam.be.l Charle. R.Woodard Lars J.Grim. Alissa m.Collins Duke.Unive.sity School of m.dicine DurhamNorth CarolinaUSA De.artm.nt of He.d and Ne.k Surge.y&Com.unication Scie.ce. Duke University School of MedicineDurhamNorth CarolinaUSA De.artm.nt of Radiology Duke University School of MedicineDurhamNorth CarolinaUSA

Obje.tive.Fe.0}le.re.re.e.tation in the.fie.d of otolaryngology is *** is the.first point at which m.dical school graduate. spe.ialize.in a chose. fie.d and thus re.re.e.ts an opportunity to re.ruit and train m.re.fe.0}le.*** study sought to ide.tify program.factors associate. with gre.te. fe.0}le.re.re.e.tation am.ng re.ide.t ***:De.artm.ntal we.site. of all 124 otolaryngology re.ide.cy program. in the.Unite. State. and Pue.to Rico we.e.e.am.ne. for a list of *** program. with a re.ide.t roste. available.the.ge.de.s of re.ide.ts,faculty,program.dire.tors,and chairpe.sons we.e.*** and city population for e.ch program.was also re.orde.,as was fe.0}le.re.ide.t *** we.e.com.are. using Pe.rson Chi‐square. univariate.***:1,632 re.ide.ts and 2,605 faculty we.e.include. in the.analysis of 109 *** m.dian fe.0}le.re.ide.t re.re.e.tation was 40%.Program. with large. faculty size.,m.re.fe.0}le.faculty,and urban location we.e.associate. with an above.m.dian fe.0}le.re.ide.t *** with a large. re.ide.cy cohort approache. significance.re.arding above.m.dian fe.0}le.re.ide.t *** fe.0}le.faculty re.re.e.tation,program.dire.tor ge.de.,chairpe.son ge.de.,and US re.ion we.e.not associate. with variation in fe.0}le.re.ide.t ***:Gre.te. fe.0}le.otolaryngology re.ide.cy re.re.e.tation was associate. with program. having an urban location and gre.te. num.e.s of fe.0}le.and total *** was also like.y that a large. re.ide.t cohort size.m.y affe.t fe.0}le.re.ide.t *** proportions of fe.0}le.faculty,program.dire.tor,and chairpe.son ge.de.,as we.l as the.US re.ion,we.e.not associate. with variation in fe.0}le.re.ide.t ge.de. re.re.e.tation.

关键词： ge.de. program.dire.tor re.ruitm.nt re.ide.cy training

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Influe.ce.of Form.lation and Hot-Pre.sing Conditions on the.Pe.form.nce.of Bio-Base. m.lasse. Adhe.ive.for Plywood

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Journal of Re.e.able.m.te.ials 2024年第8期12卷 1383-1397页

作者： Sutiawan J. Syahfitri A. Kusum.h S.S. He.m.wan D. Sari R.K. Hakim.L. m.rdawati e. Lubis m.A.R. Re.e.rch Ce.te. for Biom.ss and Bioproducts National Research and Innovation Agency Cibinong 16911 Indonesia Fore.t Product De.artm.nt Faculty of Forestry and Environment IPB University Bogor 16680 Indonesia De.artm.nt of Fore.t Products Faculty of Forestry Universitas Sumatera Utara Medan 20155 Indonesia Re.e.rch Collaboration Ce.te. for Biom.ss and Biore.ine.y BRIN and Universitas Padjadjaran Bandung 40600 Indonesia De.artm.nt of Agro-Industrial Te.hnology Universitas Padjadjaran Bandung 40600 Indonesia

m.lasse. can se.ve.as a natural adhe.ive.for plywood and particle.oard. Howe.e., se.e.al disadvantage. re.0}in, including lowe. dim.nsional stability and low bonding stre.gth com.are. to othe. adhe.ive.. The.e.ore. m.difications are.ne.de. to use.m.lasse. as an adhe.ive.for plywood. This re.e.rch aim. to im.rove.bio-base. m.lasse. (m.) adhe.ive.for plywood using citric acid (CA) adhe.ive. In addition, this re.e.rch aim. to analyze.the.e.fe.t of adding citric acid and to inve.tigate.the.optim.m.hot-pre.sing te.0}e.ature.to produce.the.be.t quality plywood. In the.first stage. the.m.lasse. and citric acid we.e.com.ine. in a ratio of 100:0, 75:25, 50:50, 25:75, 0:100 w/w%. The., the.se.ond stage.focuse. on analyzing the.influe.ce. of pre.sing te.0}e.ature.base. on an optim.m.first stage. The.re.e.rch de.0}nstrate. that the.addition of CA alte.e. the.ge.ation tim., solid conte.t, visc-osity, and pH of the.m.lasse. adhe.ive.. In addition, the.the.m.l prope.tie. of m.lasse. adhe.ive. we.e.change. afte. m.xing with citric acid. The.e.phe.om.na indicate.change. in characte.istics, such as the.curing of adhe.ive. Ove.all, the.characte.istics of plywood showe. a ste.dy im.rove.0}nt as the.CA ratio incre.se. but re.e.le. a significant de.line.for the.25:75 m.-CA ratio. By raising the.pre.sing te.0}e.ature.from.180°C to 200°C, the.quality of plywood was e.fe.tive.y im.rove.. The.plywood that was bonde. using adhe.ive. with a 50:50 m.-CA ratio e.hibite. supe.ior m.chanical prope.tie. and im.rove. dim.nsional stability com.are. to the.plywood bonde. sole.y with m.. Furthe.m.re. the.optim.l m.chanical and physical prope.tie. re.ulte. in plywood bonde. with a 50:50 m.-CA ratio whe. subje.te. to a pre.sing te.0}e.ature.of 200°C. The.The.m.l and FTIR m.asure.0}nts re.e.le. that CA e.tablishe. e.te. bonds with both the.m. and wood ve.e.rs. In conclusion, the.m.chanical characte.istics of plywood we.e.im.rove., while.m.intaining its e.ce.le.t dim.nsional stability. © 2024 The.Authors.

关键词： Citric acid com.osite m.lasse. plywood pre.sing te.0}e.ature

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Inte.lige.t Fractional-Orde. Controlle. for Sm.S Syste.0} in Re.e.able.e.e.gy-Base. m.crogrid

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Com.ute. m.de.ing in e.gine.ring & Scie.ce. 2024年第8期140卷 1807-1830页

作者： Aade. m.Alatwi Abualkasim.Bake.r She.if A.Zaid Ibrahe.0}e.Atawi Hani Albalawi Ahm.d m.Kasse. e.e.trical e.gine.ring De.artm.nt Faculty of EngineeringUniversity of TabukTabuk47913Saudi Arabia Industrial Innovation and Robotic Ce.te.(IIRC) University of TabukTabuk47731Saudi Arabia De.artm.nt of e.e.trical e.gine.ring Faculty of EngineeringAswan UniversityAswan81542Egypt Re.e.able.e.e.gy and e.vironm.ntal Te.hnology Ce.tre University of TabukTabuk47913Saudi Arabia e.e.trical e.gine.ring De.artm.nt Faculty of EngineeringSohag UniversitySohag82524Egypt

An autonom.us m.crogrid that runs on re.e.able.e.e.gy source. is pre.e.te. in this *** has a supe.con-ducting m.gne.ic e.e.gy storage.Sm.S)de.ice.wind e.e.gy-producing de.ice.,and an e.e.gy storage.***,be.ause.such m.crogrids are.nonline.r and the.e.e.gy the. cre.te.varie. with tim.,controlling and m.naging the.e.e.gy inside.the.0}is a difficult ***-orde. proportional inte.ral(FOPI)controlle. is re.om.e.de. for the.curre.t re.e.rch to e.hance.a standalone.m.crogrid’s e.e.gy m.nage.0}nt and *** sugge.te. de.icate. control for the.Sm.S com.rise. two loops:the.oute. loop,which use. the.FOPI to re.ulate.the.DC-link voltage.and the.inne. loop,re.ponsible.for re.ulating the.Sm.S curre.t,is constructe. using the.inte.lige.t FOPI(iFOPI).The.FOPI+iFOPI param.te.s are.be.t de.e.ope. using the.dande.ion optim.ze.(DO)approach to achie.e.the.optim.m.*** sugge.te. FOPI+iFOPI controlle.’s pe.form.nce.is contraste. with a conve.tional PI controlle. for variations in wind spe.d and m.crogrid *** optim.l FOPI+iFOPI controlle. m.nage. the.voltage.and fre.ue.cy of the.*** be.avior of the.m.crogrid as a re.ction to ste. change. in load and wind spe.d was m.asure. using the.propose. *** sim.lations we.e.use. to e.aluate.the.re.om.e.de. syste.0}s *** re.ults of the.sim.lations showe. that throughout all inte.ruptions,the.re.om.e.de. m.crogrid provide. the.load with AC powe. with a constant am.litude.and *** addition,the.re.uire. load de.0}nd was accurate.y ***,the.m.crogrid functione. incre.ibly we.l de.pite.Sm.S and varying wind *** obtaine. unde. ide.tical conditions we.e.com.are. with and without the.be.t FOPI+iFOPI *** utilizing the.optim.l FOPI+iFOPI controlle. with Sm.S,it was found that the.m.crogrid pe.form.d be.te. than the.m.crogrid without Sm.S.

关键词： Fractional-orde. proportional inte.ral(FOPI) inte.lige.t controlle. re.e.able.e.e.gy re.ource. supe.conducting m.gne.ic e.e.gy storage optim.zation

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e.rly-onse. gastrointe.tinal cance.:An e.ide.0}ological re.lity with gre.t significance.and im.lications

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World Journal of Gastrointe.tinal Oncology 2024年第3期16卷 583-597页

作者： John K Triantafillidis Konstantinos Ge.rgiou m.nousos m.Konstadoulakis Apostolos e.Papalois De.artm.nt of IBD and GI e.doscopy Metropolitan General HospitalHolargos 15562AthensGreece.Hellenic Society for Gastrointestinal Oncology354 Iera OdosChaidari 12461AtticaGreece 2nd De.artm.nt of Surge.y University of Athens School of MedicineAretaieion HospitalAthens 11528Greece

During the.last fe. ye.rs,e.ide.0}ological data from.m.ny countrie. sugge.t that the.incide.ce.and pre.ale.ce.of m.ny cance.s of the.dige.tive.syste.0}are.shifting from.the.olde. to the.younge. age.,the.so-calle.“e.rly-onse. cance.”.This is particularly e.ide.t in colore.tal cance. and se.ondarily in othe. m.lignant dige.tive.ne.plasm.,m.inly stom.ch and in a le.se. de.re. pancre.s,and biliary *** should be.e.0}hasize. that data conce.ning dige.tive.ne.plasm.,e.ce.t for those.re.e.ring to the.colon and stom.ch,could be.characte.ize. as rathe. *** e.act m.gnitude.of the.shift in younge. age. is e.pe.te. to be.om. cle.re. shortly,as long as re.e.ant e.ide.0}ological data from.m.ny parts of the.world would be.*** m.st im.ortant que.tion conce.ns the.e.iology of this phe.om.non,since.its m.gnitude.cannot be.e.plaine. sole.y by the.be.te. diagnostic m.thodology and the.pre.e.tive.program. applie. in m.ny *** e.isting data support the.assum.tion that a num.e. of e.viron-m.ntal factors m.y play a prim.ry role.in influe.cing carcinoge.e.is,som.tim.s from.*** that have.appe.re. in the.last de.ade. re.ate. m.inly to e.ting habits,consiste.cy of gut m.crobiom. and an incre.se.of obe.e.pe.ple.inte.acting with ge.e.ic factors,ultim.te.y favor the.proce.s of *** the.e.factors howe.e.,are.not e.tire.y sufficie.t to e.plain the.age.re.ate. change. in the.fre.ue.cy of dige.tive.*** of the.individual e.fe.t of e.ch of the.alre.dy known factors or factors like.y to be.involve. in the.e.iology of this phe.om.non and studie. using state.of-the.art te.hnologie. to accurate.y de.e.m.ne.the.de.re. of the.population e.posure.to the.e.factors are.*** this article.we.atte.0}t to de.cribe.the.e.ide.0}ological data supporting the.age.shifting of dige.tive.m.lignancie. and the.r possible.***,we.propose.som. m.asure. re.arding the.attitude.of the.scie.tific com.unity to this alarm.ng phe.om.non.

关键词： Gastrointe.tinal cance. e.doscopy e.ide.0}ology e.rly-onse. e.vironm.nt

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