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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1910-1917页

作者： Akihiro Cho Satoshi Katagiri Masao Ota Shunsuke Onizawa Ryota Higuchi Toshiya Sugishita Yukiko Niwa Takeshi Ishita Toshihiko Mouri Akita Kato moe iwata Division of Gastroenterological Surgery Tokyo Women’s Medical UniversityYachiyo Medical CenterChiba 276-8524Japan

BACKGROUND Emergency pancreaticoduodenectomy(EPD)is a rare event for complex periam-pullary *** intraoperative blood loss is correlated with poor post-operative *** SUMMARY Two patients underwent EPD using a no-touch isolation technique,in which all arteries supplying the pancreatic head region were ligated and divided before manipulation of the pancreatic head and *** operative times were 220 and 239 min,and the blood loss was 70 and 270 g,*** patients were discharged on the 14^(th) and 10^(th) postoperative day,***-two patients underwent EPD for the treatment of neoplastic *** mean operative time was 361.6 min,and the mean blood loss was 747.3 *** comp-lication rate was 37.5%.The in-hospital mortality rate was 9.38%.CONCLUSION The no-touch isolation technique is feasible,safe,and effective for reducing intraoperative blood loss in EPD.

关键词： No-touch isolation technique Pancreaticoduodenectomy Emergency pancre-aticoduodenectomy Neoplastic bleeding Superior mesenteric artery first approach Case report

碰撞激活诱导的双势阱势能面可以实现9-甲基-8-氧鸟嘌呤-9-甲基腺嘌呤碱基对阳离子自由基的质子转移

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Chinese Journal of Chemical Physics 2024年第2期37卷 330-340,I0022-I0039,I0104页

作者： May Myat moe 刘剑波美国纽约城市大学皇后学院化学与生物化学系纽约11367 美国纽约城市大学研究生院纽约10016

8-氧鸟嘌呤(OG)是最常见的核碱基氧化损伤,它在复制过程中可以用Hoogsteen的模式与腺嘌呤(A)错误配对.0G.A碱基对不仅可以诱发G·C→T·A的颠换突变,而且由于OG的电离势和氧化电位低于天然DNA碱基更容易受到电离辐射和单电子氧化的影响... 详细信息

8-氧鸟嘌呤(OG)是最常见的核碱基氧化损伤,它在复制过程中可以用Hoogsteen的模式与腺嘌呤(A)错误配对.0G.A碱基对不仅可以诱发G·C→T·A的颠换突变,而且由于OG的电离势和氧化电位低于天然DNA碱基更容易受到电离辐射和单电子氧化的影响,本文报道了[9MOG·9MA]^(·+)碱華对阳离子自由基的形成.和碰撞诱导解离,该碱基对利用9-甲基8-氧鸟嘌呤(9MOG)和9-甲基腺嘌呤(9MA)模拟相对应的核苷酸.实验通过电喷雾产生Cu(Ⅱ)碱基复合物继之以氧化分离产生[9MOG·9MA]^(·+),并使用导向离子束串级质谱仪检测[9MOG·9MA]^(·+)的碰撞诱导解离、通过测量在不同碰撞能量下的解离产物和反应截面,可以得出[9MOG-H]+[9MA+H]^(+)(主要解离通道)和9MOG^(·+)+9MA(次要通道)的0 K解离阈能分别为1.8和1.65 eV.使用密度泛函理论对[9MOG·9MA]^(·+)的结构计算发现其所有重要构象都发生了质子转移生成[9MOG-H]^(·)·[9MA+H]^(+).另一方面,9MOG^(·+)+9MA的解离通道却需要9MOG^(·+)9MA作为中间体.看似矛盾的结果可以用碰撞活化后反应势能面上出现的双重势阱和由此触发的激发态质子转移平衡([9MOG-H]^(·)·[9MA+H]^(+))^(*)→←(9MOG6(·+)·9MA)^(*)来解释.本文实验和理论研究揭示了这种生物学上重要的非规范碱基对如何在氧化和电离损伤时发生解离.

关键词：碱基对阳离子自由基碰撞诱导解离碱基对内质子转移反应势能面电喷雾电离质谱导向离子束散射

Multi-environment BSA-seq using large F3 populations is able to achieve reliable QTL mapping with high power and resolution: An experimental demonstration in rice

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The Crop Journal 2024年第2期12卷 549-557页

作者： Yan Zheng Ei Ei Khine Khin Mar Thi Ei Ei Nyein Likun Huang Lihui Lin Xiaofang Xie Min Htay Wai Lin Khin Than Oo Myat Myat moe San San Aye Weiren Wu College of Life Sciences Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Fujian Provincial Key Laboratory of Crop Breeding by Design Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Key Laboratory of Genetics Breeding and Multiple Utilization of CropsMinistry of EducationFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Department of Botany Mawlamyine UniversityMon StateMawlamyineMyanmar Department of Botany Dagon UniversityNorth DagonYangonMyanmar

Bulked-segregant analysis by deep sequencing(BSA-seq) is a widely used method for mapping QTL(quantitative trait loci) due to its simplicity, speed, cost-effectiveness, and efficiency. However, the ability of BSA-seq to detect QTL is often limited by inappropriate experimental designs, as evidenced by numerous practical studies. Most BSA-seq studies have utilized small to medium-sized populations, with F2populations being the most common choice. Nevertheless, theoretical studies have shown that using a large population with an appropriate pool size can significantly enhance the power and resolution of QTL detection in BSA-seq, with F_(3)populations offering notable advantages over F2populations. To provide an experimental demonstration, we tested the power of BSA-seq to identify QTL controlling days from sowing to heading(DTH) in a 7200-plant rice F_(3)population in two environments, with a pool size of approximately 500. Each experiment identified 34 QTL, an order of magnitude greater than reported in most BSA-seq experiments, of which 23 were detected in both experiments, with 17 of these located near41 previously reported QTL and eight cloned genes known to control DTH in rice. These results indicate that QTL mapping by BSA-seq in large F_(3)populations and multi-environment experiments can achieve high power, resolution, and reliability.

关键词： BSA-seq QTL mapping Large F3 population Multi-environment experiment Cross-validation

Risk and Protective Factors Associated with Depression and Anxiety among Pregnant Women during the COVID-19 Pandemic

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Health 2024年第1期16卷 37-51页

作者： Maiko Manaka Miyako Tsuda moe Fujitani Ai Sawada Nanae Akatsuka Ayako Sasaki Faculty of Nursing Osaka Medical and Pharmaceutical University Takatsuki Japan Osaka City Juso Hospital Osaka Japan Osaka City General Hospital Osaka Japan

Background: The coronavirus disease (COVID-19) pandemic has impacted perinatal women’s mental health. However, protective factors associated with depression among pregnant Japanese women during the pandemic have not been reported. Purpose: The present study investigated the risk and protective factors associated with depression and anxiety among pregnant women during the COVID-19 pandemic. Methods: An online questionnaire was administered to 157 pregnant women between October 2022 and May 2023 at two general hospitals in Japan. The Japanese versions of the Patient Health Questionnaire-9 (PHQ-9) and General Anxiety Disorder-7 (GAD-7) were used to assess symptoms of depression and anxiety. The χ2 test or Fisher’s exact test and multivariate logistic regression model were used to examine factors associated with depression and anxiety among pregnant women. Results: Overall, 47.1% and 35.7% of the pregnant women reported depressive and anxiety symptoms, respectively. A “history of mental illness” was a risk factor for depression and anxiety among pregnant women during the COVID-19 pandemic. Additionally, unmarried status was a risk factor for anxiety among pregnant women, whereas outdoor and indoor exercises were protective factors against depression and anxiety, respectively. Conclusions: Exercise may have protected pregnant women from depression and anxiety during the COVID-19 pandemic. Encouraging exercise may help maintain the mental health of pregnant women who do not have exercise restrictions.

关键词： Depression Anxiety Factors Pregnancy COVID-19 Pandemic

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立体绒织物的三维虚拟设计

染整技术 2024年第4期46卷 41-47页

作者：王靓靓 Kyaw Win moe 陈敏之浙江理工大学服装学院浙江杭州310018 浙江理工大学国际教育学院浙江杭州310018

为了提高立体绒织物在数字时尚方面的设计效率,针对其外观效果还原的复杂性与软件设置参数调整的盲目性,提出了一种基于参数转化和图像处理的虚拟绒织物设计方法。在建立织物外观特征参数与软件设置参数对照表的基础上,构建软件设置参... 详细信息

为了提高立体绒织物在数字时尚方面的设计效率,针对其外观效果还原的复杂性与软件设置参数调整的盲目性,提出了一种基于参数转化和图像处理的虚拟绒织物设计方法。在建立织物外观特征参数与软件设置参数对照表的基础上,构建软件设置参数与绒毛结构参数的转化量表。根据织物外观特征及转化量表,利用纹理叠加、模糊处理等计算机图像技术完成二维贴图的快速生成与修改,通过style3D所拥有的毛皮渲染模块对立体绒织物进行三维建模与变化应用。结果表明:该方法利用二维贴图使立体绒织物数字化模型的外观凹凸效果更加显著,并能够快速完成模型重构,操作简易方便,准确清晰地模拟高度差明显的立体绒织物。

关键词：立体绒织物三维虚拟设计计算机图像技术纹理叠加二维贴图

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Development of a modified predicted heat strain model for hot work environments

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International Journal of Mining Science and Technology 2020年第4期30卷 477-481页

作者： Paloma Lazaro moe Momayez Department of Mining and Geological Engineering The University of ArizonaTucsonAZ 85750USA

Excessive exposure to heat can lead to injuries,illness,and death among *** actual cost of heat-related injuries and illnesses is unknown because of underreporting and lack of symptom ***-factorial,evidence-based,and field-ready guidelines for identifying–and predicting–physiolo gical markers of heat strain are currently *** predicted heat strain(PHS)model,is the latest attempt by mining companies to aid in the evaluation and management of occupational heat *** adopted algorithm relies on worksite environmental measurements and an estimate of individual metabolic rate for mine workers to provide an estimate of the workers’core temperature during a work *** are several known limitations of the PHS model,including the assumption that the subject worker is hydrated and fit.A modified PHS model was presented based on eight physical parameters that are measured at different intervals during a work shift;these parameters are air temperature,relative humidity,air velocity,radiation,metabolic rate,acclimatization,clothing insulation and *** validate the results,the predictions from the modified PHS model were compared with direct physiological measurements obtained from ingestible pills and heat stress monitors under different environmental and working conditions.

关键词： Predicted heat strain Hot underground mines Heat strain Heat stress

Silicification in Mississippian Lodgepole Formation,Northeastern Flank of Williston Basin,Manitoba,Canada

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Journal of Earth Science 2012年第1期23卷 1-18页

作者： Harvey R Young moe Kuroda Department of Geology Brandon University

Five types of replacement silica are recognized in the Lower Mississippian Virden Member carbonates on the northeastern flank of Williston basin： microcrystalline quartz, chalcedonic quartz, anhedral megaquartz, euhedral megaquartz, and stringy megaquartz. Silica tends to replace various bioclasts, and all except the stringy megaquartz also occur as non-replacive void-filling cement or as silica forming chert nodules and silicified limestone. Although crinoids, brachiopods, corals, bryozoans, molluscs, trilobites, forams, and ostracodes are present in the sediments studied, only the first three show evidence of silicification. Crinoids are commonly replaced by microcrystalline quartz whereas brachiopods typically by spherules of length slow chalcedony. Coalesced spherules, often in concentric rings （beekite rings）, may form sheet-like masses on the surface of corals and brachiopods. Although bryozoans are common in the Virden Member, none showed any evidence of silicification. The difference in the susceptibility to silicification may be related to the shell microstructure, biological group, size of organism, skeletal mineralogy, and organic content of the bioclasts. Biogenic silica derived from the dissolution of siliceous sponge spicules is considered to be the most likely silica source for silicification. Most silica is believed to be released during early diagenesis before the sediments were deeply buried. The Virden Member carbonate may have experienced two episodes of replacement, the first affecting the bioclasts, the second producing silicified limestone and chert nodules.

关键词： silicification Williston basin Lodgepole Formation Virden Member Mississippian carbonate.

Computer Simulation of Dynamic Interactions Between Vehicle and Long Span Box Girder Bridges

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Tsinghua Science and Technology 2008年第S1期13卷 71-77页

作者： moe S. Cheung Department of Civil Engineering University of Ottawa

Moving vehicle loads, associated with roadway traffic can induce significant dynamic effects on the structural behaviours of bridges, especially for long-span bridges. The main objective of current research is to study traffic induced dynamic responses of long-span box-girder bridges. The finite element method has been employed in this study to obtain a three-dimensional mathematical model for the bridge system. For vehicle-bridge dynamic interaction analysis, the vehicle is modeled as a more realistic three-axle, six-wheel system, and the corresponding dynamic interaction equations have been derived. The bridge-vehicle interaction is affected by many factors. The current study has been focused on such factors as: vehicle speed, vehicle damping ratio, multiple traffic lanes, mass ratio of vehicle and bridge, and dynamic characteristics of bridge. Case studies have been conducted to investigate these factors by using several box girder bridge examples including Confederation Bridge, the longest box girder bridge in the world.

关键词： vibration box girder bridge long-span bridge-vehicle interaction finite element analysis

“Waste”-ing away:Presence of Cu ions influences microbial degradation kinetics and metabolite formation of the prevalent brominated flame retardant BDE-47

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Journal of Environmental Sciences 2020年第1期32卷 421-424页

作者： Jie Chen Birget moe Lizhong Zhu X.Chris Le Department of Environmental Science Zhejiang UniversityHangzhou 310058China Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control Hangzhou 310058China Division of Analytical and Environmental Toxicology Department of Laboratory Medicine and PathologyUniversity of AlbertaEdmontonT6G 2G3AlbertaCanada Alberta Centre for Toxicology Department of Physiology and PharmacologyUniversity of CalgaryCalgaryT2N 4N1AlbertaCanada Department of Environmental Science Zhejiang UniversityHangzhou310058China Zhejiang Provincial Key Laboratory of Organic Pollution Process and Control Hangzhou310058China

Have you ever wondered what happened to that old cell phone you threw out last month?How about the 150 million other cell phones that were also disposed of in the past year?Although the world population has doubled in the past 50 years,global consumption of electronic devices has increased six fold(Belkhir and Elmeligi,2018)with nearly 45 million tonnes of electronic waste(e-waste)being produced in 2016 alone(Balde et al.,2017).That equates to 6.1 kg of e-waste per person across the globe and is equivalent in weight to over four thousand Eiffel towers(Balde et al.,2017)!

关键词： BDE-47 Polybrominated diphenyl ethers Copper Pycnoporus sanguineus Microbial degradation Metabolites E-waste

Effects of halobenzoquinone and haloacetic acid water disinfection byproducts on human neural stem cells

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Journal of Environmental Sciences 2017年第8期29卷 239-249页

作者： Katherine Z.Fu Jinhua Li Sai Vemula Birget moe Xing-Fang Li Division of Analytical&Environmental Toxicology Department of Laboratory Medicine&PathologyFaculty of Medicine&DentistryUniversity of Alberta Alberta Centre for Toxicology Department of Physiology&PharmacologyFaculty of MedicineUniversity of Calgary

Human neural stem cells（h NSCs） are a useful tool to assess the developmental effects of various environmental contaminants; however, the application of h NSCs to evaluate water disinfection byproducts（DBPs） is scarce. Comprehensive toxicological results are essential to the prioritization of DBPs for further testing and regulation. Therefore, this study examines the effects of DBPs on the proliferation and differentiation of h NSCs. Prior to DBP treatment, characteristic protein markers of h NSCs from passages 3 to 6 were carefully examined and it was determined that h NSCs passaged 3 or 4 times maintained stem cell characteristics and can be used for DBP analysis. Two regulated DBPs, monobromoacetic acid（BAA） and monochloroacetic acid（CAA）, and two emerging DBPs, 2,6-dibromo-1,4-benzoquinone（2,6-DBBQ） and 2,6-dichloro-1,4-benzoquinone（2,6-DCBQ）, were chosen for h NSC treatment. Both 2,6-DBBQ and 2,6-DCBQ induced cell cycle arrest at S-phase at concentrations up to 1 μmol/L. Comparatively, BAA and CAA at 0.5 μmol/L affected neural differentiation. These results suggest DBP-dependent effects on h NSC proliferation and differentiation. The DBP-induced cell cycle arrest and inhibition of normal h NSC differentiation demonstrate the need to assess the developmental neurotoxicity of DBPs.

关键词： Disinfection byproducts Human neural stem cells Differentiation Halobenzoquinones Haloacetic acids Cell cycle arrest