检索结果-南通市图书馆

Hepatoprotective effect of Holothuria leucospilota methanolic extract on dimethyl nitrosamine-induced hepatotoxicity in rats

引用

Animal models and Experimental Medicine 2024年第4期7卷 544-552页

作者： Fatemeh Dejan Amineh Daneshi Javad Rajabi Aslani Nasrollah Ahmadi Narges Eskandari Roozbahani Elaham Rahmanian reza Behmanesh Hamid reza Gheisari Department of Basic Sciences School of Veterinary MedicineShiraz UniversityShirazIran Department of Education Farzanegan High SchoolTehranKohgiluyeh and Boyer AhmadIran Food Hygiene Department School of Veterinary MedicineShiraz UniversityShirazIran Department of Pathology School of Veterinary MedicineShiraz UniversityShirazIran Clinical Research Development Center Imam Reza HospitalKermanshah University of Medical SciencesKermanshahIran molecular Dermatology Research Center Shiraz University of Medical SciencesShirazIran Department of Anatomy School of MedicineShiraz University of Medical SciencesShirazIran Faculty of Veterinary Medicine Garmsar BranchDepartment of RadiologyIslamic Azad UniversityGarmsarIran

Background:Complementary medicine is an interesting field for extracting bio-active compounds from various plant and animal *** hepatoprotective effect of the methanolic extract of a species of sea cucumber called Holothuria leu-cospilota in an animal model of liver cancer caused by dimethyl nitrosamine(DMN)was ***:Wistar female rats were randomly divided into five groups(n=12):control(intact),positive control(received 1%DMN[10 mg/kg/week,intraperitoneally]for 12 weeks),and three treatment groups(received 50,100,and 200 mg/kg/day ***-cospilota extract orally for 12 weeks along with intraperitoneal administration of 1%DMN[10 mg/kg/week]).In all groups,ultrasound was performed on the liver every week to check its *** sampling and liver isolation were performed on three occasions,at 4,8,and 12 weeks,to check liver enzymes and the histopathological condition of the liver tissue(every week,four animals from each group were randomly selected).Results:Liver density changes were evident from the eighth week onward in the positive control *** results indicated pathologic changes in the positive control group after 4 *** increase in liver enzymes in the posi-tive control group was significantly different from that in the treatment and control ***:We demonstrated the hepatoprotective effect of *** on DMN-induced liver damage in rats using biochemical and histological parameters and *** additional research(in silico or in vitro)is needed to find the exact mechanism and the main biological compound in ***.

关键词： dimethyl nitrosamine hepatotoxicity Holothuria leucospilota sea cucumber

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Towards a lightweight security framework using blockchain and machine learning

引用

Blockchain(Research and Applications) 2024年第1期5卷 107-118页

作者： Shereen Ismail Muhammad Nouman diana W.Dawoud Hassan reza School of Electrical Engineering and Computer Science University of North DakotaND 58202USA Department of Computer Science COMSATS University IslamabadIslamabad 44000Pakistan College of Engineering and Information Technology University of DubaiDubaiUnited Arab Emirates

Cyber-attacks pose a significant challenge to the security of Internet of Things(IoT)sensor networks,necessitating the development of robust countermeasures tailored to their unique characteristics and *** prevention and detection techniques have been proposed to mitigate these *** this paper,we propose an integrated security framework using blockchain and Machine Learning(ML)to protect IoT sensor *** framework consists of two modules:a blockchain prevention module and an ML detection *** blockchain prevention module has two lightweight mechanisms:identity management and trust *** management employs a lightweight Smart Contract(SC)to manage node registration and authentication,ensuring that unauthorized entities are prohibited from engaging in any tasks,while trust management uses a lightweight SC that is responsible for maintaining trust and credibility between sensor nodes throughout the network’s lifetime and tracking historical node *** and transaction validation are achieved through a Verifiable Byzantine Fault Tolerance(VBFT)mechanism to ensure network reliability and *** ML detection module utilizes the Light Gradient Boosting Machine(LightGBM)algorithm to classify malicious nodes and notify the blockchain network if it must make decisions to mitigate their *** investigate the performance of several off-the-shelf ML algorithms,including Logistic Regression,Complement Naive Bayes,Nearest Centroid,and Stacking,using the WSN-DS *** is selected following a detailed comparative analysis conducted using accuracy,precision,recall,F1-score,processing time,training time,prediction time,computational complexity,and Matthews Correlation Coefficient(MCC)evaluation metrics.

关键词： Blockchain Machine learning IoT Security Integration Smart contracts

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Rosmarinic acid improves tracheal smooth muscle responsiveness and lung pathological changes in ovalbumin-sensitized rats

引用

Asian Pacific Journal of Tropical Biomedicine 2024年第3期14卷 100-105页

作者： Vahideh Abbasnia mohsen Foadoddini Delaram Eslimi Esfahani mo.ammad reza Khazdair Shahrbanoo Oryan Department of Biology Payame Noor UniversityTehranIran Cardiovascular diseases Research Center Birjand University of Medical SciencesBirjandIran Department of Animal Sciences Faculty of Biological SciencesKharazmi UniversityTehranIran

Objective:To evaluate the effect of rosmarinic acid on tracheal smooth muscle responsiveness and lung pathological changes in ovalbumin-sensitized ***:Rats were randomly divided into six groups:the control group,the asthmatic group,and the asthmatic groups treated with dexamethasone(1 mg/kg;oral gavage)or three doses of rosmarinic acid(0.5,1,and 2 mg/kg;oral gavage).For induction of asthma,rats received intraperitoneal injections and inhalation of *** 21 days,bronchoalveolar lavage fluid and lung samples were collected for histopathological ***,total and differential white blood cell counts were ***:The rosmarinic acid-treated group had significantly lower tracheal smooth muscle responses to methacholine than the asthmatic *** addition,rosmarinic acid reduced white blood cell count and the percentages of eosinophils,monocytes,and neutrophils while increasing the percentage of ***-induced lung pathological changes were significantly improved by treatment with rosmarinic ***:Rosmarinic acid improves tracheal smooth muscle responsiveness and lung pathological changes in ovalbumin-sensitized rats.

关键词： Rosmarinic acid Asthma Ovalbumin Tracheal responsiveness Inflammation White blood cell

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The nature and movement of thrusts in the eastern Iranian orogen:Sechengi Area on the northern border of Lut and Sistan

引用

Journal of mountain Science 2024年第9期21卷 3157-3171页

作者： Shahriar KESHTGAR Mahmoud reza HEYHAT Sasan BAGHERI Ebrahim GHOLAMI Seyed Naser RAIsoSSADAT Department of Geology Faculty of ScienceUniversity of BirjandBirjand ***Iran Department of Geology Faculty of ScienceUniversity of Sistan and BaluchestanZahedan 98167-45845Iran

The eastern Iranian range,known as the Sistan suture zone in the past,has recently been identified as the Sistan *** Paleogene orogeny is located between the Lut and Afghan *** structural analysis shows that most of the thrusts dip towards the NW so that the Permo-Triassic sediments and Jurassic micro-diorites of the Lut Block overthrusted over the younger *** studies show that the tectonic vergence was from the NW to the SE of the Sechengi area in the NW part of Sistan *** recognized three deformation phases in eastern *** first N-S deformation event(D1)resulted in the formation of tight E-W folds(F1)and associated cleavages(S1).The second E-W deformation event(D2),which occurred in the late Paleogene led to the bending of older structures,including the axial plane of the first-generation folds giving them a new northwest direction(F2).Additionally,the ramp of the first-phase thrusts(striking E-W)was reactivated,acquiring a new NNW orientation and exhibiting SSE tectonic *** third deformation event(D3)resulted in the formation of NNE and WNW conjugate faults in eastern *** consecutive deformation events perpendicular to each other are inconsistent with the models of simple linear orogen presented for eastern Iran(*** of eastern Iran continental crust and subsequence linear collision)and seem more consistent with the buckling orogeny(Orocline).

关键词： Thrust Tectonic vergence Orocline Buckling Sechengi Eastern Iranian ranges.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

modeling functional brain connections in methamphetamine and opioid abusers

引用

Medicine in Novel Technology and Devices 2024年第1期21卷 88-96页

作者： Nasimeh Marvi Javad Haddadnia mo.ammad reza Fayyazi Bordbar Hakim Sabzevari University SabzevarIran Psychiatry and Behavioral Sciences Research Center Mashhad University of Medical SciencesMashhadIran

Substance abuse has become a significant problem *** primary purpose of this study was to model the functional brain connectivity in methamphetamines(Meth)and opioids(Op)groups in comparison with the healthy control(HC)*** data were recorded in Meth(n=8),Op(n=12),and HC groups(n=12)in a closed-eye resting *** NeuCube model based on a spiking neural network was used for EEG data's functional brain connectivity *** NeuCube model was evaluated quantitatively and qualitatively with model descriptive *** results showed the average value of the neuron's activation level,spikes emitted from neurons,and clustering coefficient as a communication parameter in the HC group decreased from 1154,1103,0.026 to 1036,981,0.020 in the Op group and to 511,468,0.009 in the Meth group,*** changes in indices were significant according to the ANOVA test with p〈*** decrease in indices was more significant in the Meth group than in the Op *** research findings showed that the abuse of Meth and Op causes damage to the brain's functional *** damage included shortening and limiting communication routes and decreased neurons'ability to generate membrane potential and emit inhibitory and excitatory *** were reported to be more severe in the Meth group than in the Op group.

关键词： Electroencephalogram Methamphetamines NeuCube model Opioids Spiking neural networks

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

原油沥青质含量对纳米颗粒-十二烷基硫酸钠发泡二氧化碳泡沫稳定性的影响

引用

石油勘探与开发 2024年第1期51卷 212-222页

作者： SADEGHI Hossein KHAZ'ALI Ali reza mo.ammadI mohsen 伊斯法罕理工大学化学工程系伊朗伊斯法罕84156-83111 丹麦技术大学丹麦海洋工程技术中心丹麦灵比2800

采用十二烷基硫酸钠(SDS)表面活性剂和SiO_(2)纳米颗粒作为发泡体系,在不同原油沥青质含量下进行泡沫稳定性实验,测量CO_(2)泡沫半衰期;采用扫描电子显微图像、紫外分光光度法测试和Zeta电位测量,分析沥青质降低CO_(2)泡沫稳定性的机理... 详细信息

采用十二烷基硫酸钠(SDS)表面活性剂和SiO_(2)纳米颗粒作为发泡体系,在不同原油沥青质含量下进行泡沫稳定性实验,测量CO_(2)泡沫半衰期;采用扫描电子显微图像、紫外分光光度法测试和Zeta电位测量,分析沥青质降低CO_(2)泡沫稳定性的机理。研究表明:当合成油与发泡体系质量比为1∶9时,合成油沥青质质量分数从0增至15%,SDS稳定泡沫半衰期从751 s减少至239 s,SDS-SiO_(2)稳定泡沫半衰期从912 s缩短至298 s;当合成油与发泡体系质量比为2∶8时,随着沥青质质量分数增大,SDS稳定泡沫半衰期从526 s缩短至171 s,SDS-SiO_(2)稳定泡沫半衰期从660 s缩短至205 s。由于沥青质与SDS和SiO_(2)纳米颗粒在水相中的相互作用,Zeta电位绝对值减小,颗粒表面电荷降低,导致薄液膜两侧界面之间的排斥力减小,从而破坏泡沫稳定性。

关键词： CO_(2)泡沫泡沫稳定性沥青质二氧化硅纳米颗粒十二烷基硫酸钠(SDS) 排斥力表面电荷 Zeta电位

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nullors, and Nullor Circuits;There Applications in Symbolic Circuit Analysis and Design

引用

Applied Mathematics 2024年第1期15卷 33-45页

作者： reza Hashemian reza Hashemian Northern Illinois University Dekalb USA

The objective in this presentation is to introduce some of the unique properties and applications of nullors in active circuit analysis and designs. The emphasis is to discuss the role nullors can play in symbolic representation of transfer functions. To show this we adopt the topological platform for the circuit analysis and use a recently developed Admittance Method (AM) to achieve the Sum of Tree Products (STP), replacing the determinant and cofactors of the Nodal Admittance Matrix (NAM) of the circuit. To construct a transfer function, we start with a given active circuit and convert all its controlled sources and I/O-ports to nullors. Now, with a solid nullor circuit (passive elements and nullors) we first eliminate the passive elements through AM operations. This produces the STPs. Second, the all-nullor circuit is then used to find the signs or the STPs. Finally, the transfer function (in symbolic, if chosen) is obtained from the ratio between the STPs.

关键词： Admittance Method Analog Circuits Nullors Nullor Circuits Sum of Tree Products Transfer Functions

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enhancing Hyper-Spectral Image Classification with Reinforcement Learning and Advanced Multi-Objective Binary Grey Wolf Optimization

引用

Computers, Materials & Continua 2024年第6期79卷 3469-3493页

作者： Mehrdad Shoeibi mo.ammad Mehdi Sharifi Nevisi reza Salehi diego Martín Zahra Halimi Sahba Baniasadi TheWPI Business School Worcester Polytechnic InstituteWorcesterMassachusetts01609-2280USA Department of Industrial Engineering Iran University of Science and TechnologyNarmakTehran16846-13114Iran ETSI de Telecomunicación Universidad Politécnica de MadridAv.Complutense 30Madrid28040Spain Department of Civil and Environmental Engineering University of MarylandCollege ParkMaryland20742USA Department of Industrial Engineering College of EngineeringUniversity of HoustonHoustonTexas77204USA

Hyperspectral(HS)image classification plays a crucial role in numerous areas including remote sensing(RS),agriculture,and the monitoring of the *** band selection in HS images is crucial for improving the efficiency and accuracy of image *** process involves selecting the most informative spectral bands,which leads to a reduction in data *** on these key bands also enhances the accuracy of classification algorithms,as redundant or irrelevant bands,which can introduce noise and lower model performance,are *** this paper,we propose an approach for HS image classification using deep Q learning(DQL)and a novel multi-objective binary grey wolf optimizer(moBGWO).We investigate the moBGWO for optimal band selection to further enhance the accuracy of HS image *** the suggested moBGWO,a new sigmoid function is introduced as a transfer function to modify the wolves’*** primary objective of this classification is to reduce the number of bands while maximizing classification *** evaluate the effectiveness of our approach,we conducted experiments on publicly available HS image datasets,including Pavia University,Washington Mall,and Indian Pines *** compared the performance of our proposed method with several state-of-the-art deep learning(DL)and machine learning(ML)algorithms,including long short-term memory(LSTM),deep neural network(DNN),recurrent neural network(RNN),support vector machine(SVM),and random forest(RF).Our experimental results demonstrate that the Hybrid moBGWO-DQL significantly improves classification accuracy compared to traditional optimization and DL ***-DQL shows greater accuracy in classifying most categories in both datasets *** the Indian Pine dataset,the moBGWO-DQL architecture achieved a kappa coefficient(KC)of 97.68%and an overall accuracy(OA)of 94.32%.This was accompanied by the lowest root mean square error(RMSE)of 0.94,indicating very precise

关键词： Hyperspectral image classification reinforcement learning multi-objective binary grey wolf optimizer band selection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bulk-boundary and RPS thermodynamics from topology perspective

引用

Chinese Physics C 2024年第9期48卷 244-253页

作者： Jafar Sadeghi mo.ammad reza Alipour Saeed Noori Gashti mo.ammad Ali S.Afshar Department of Physics Faculty of Basic SciencesUniversity of Mazandaran P.O.Box 47416-95447BabolsarIran School of Physics Damghan UniversityP.O.Box ***DamghanIran

In this study,we investigate the bulk-boundary and restricted phase space(RPS)thermodynamics of Rissner-Nordstrom(R-N)AdS and 6-dimensional charged Gauss-Bonnet AdS black ***,we examine the topological characteristics of the considered black holes and compare them with the results of extended *** determine that the topological behavior of the bulk-boundary thermodynamics is the same as that of the extended thermodynamics,whereas the RPS thermodynamics exhibits a distinct ***,we demonstrate that within the RPS formalism,there is only one critical point with a topological charge of+1(Q_(t)=+1).moreover,in the RPS formalism,the inclusion of higher-derivative curvature terms in the form of GaussBonnet gravity does not alter the topological classification of critical points in charged AdS black holes.

关键词： bulk-boundary restricted phase space topological charge thermodynamics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Machine learning prediction of methane,ethane,and propane solubility in pure water and electrolyte solutions:Implications for stray gas migration modeling

引用

Acta Geochimica 2024年第5期43卷 971-984页

作者： Ghazal Kooti reza Taherdangkoo Chaofan Chen Nikita Sergeev Faramarz Doulati Ardejani Tao Meng Christoph Butscher Institute of Geotechnics TU Bergakademie FreibergGustav-Zeuner-Str.109599 FreibergGermany Department of Petroleum Engineering Amirkabir University of TechnologyTehranIran Freiberg Center for Water Research ZeWaF TU Bergakademie Freiberg09599 FreibergGermany School of Mining College of EngineeringUniversity of TehranTehranIran Taiyuan University of Science and Technology Taiyuan 030024China

Hydraulic fracturing is an effective technology for hydrocarbon extraction from unconventional shale and tight gas reservoirs.A potential risk of hydraulic fracturing is the upward migration of stray gas from the deep subsurface to shallow *** stray gas can dissolve in groundwater leading to chemical and biological reactions,which could negatively affect groundwater quality and contribute to atmospheric *** knowledge oflight hydrocarbon solubility in the aqueous environment is essential for the numerical modelling offlow and transport in the ***,we compiled a database containing 2129experimental data of methane,ethane,and propane solubility in pure water and various electrolyte solutions over wide ranges of operating temperature and *** machine learning algorithms,namely regression tree(RT)and boosted regression tree(BRT)tuned with a Bayesian optimization algorithm(BO)were employed to determine the solubility of *** predictions were compared with the experimental data as well as four well-established thermodynamic *** analysis shows that the BRT-BO is sufficiently accurate,and the predicted values agree well with those obtained from the thermodynamic *** coefficient of determination(R2)between experimental and predicted values is 0.99 and the mean squared error(MSE)is 9.97×10^(-8).The leverage statistical approach further confirmed the validity of the model developed.

关键词： Gas solubility Hydraulic fracturing Thermodynamic models Regression tree Boosted regression tree Groundwater contamination

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：