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Refined acoustic holography via nonlocal metasurfaces

Science China(Physics,Mechanics & Astronomy) 2024年第7期67卷 113-123页

作者： Shuhuan Xie Hongyu Ma Junmei Cao Fangshuo mo Qian Cheng Yong Li Tong Hao Institute of Acoustics School of Physics Science and EngineeringTongji UniversityShanghai 200092China Center for Spatial Information Science and Sustainable Development Applications Tongji UniversityShanghai 200092China College of Surveying and Geo-Informatics Tongji UniversityShanghai 200092China

Holography can provide the desired wavefront phase and/or amplitude for imaging,particle manipulation,bacteria trapping,and cell patterning in optics and ***,previous work on acoustic holography is mostly based on local design optimization,either using active control of the sound source or relying on the structural design to provide the desired *** precise control over the acoustic field remains a significant ***,we realize refined single-plane symmetric binary amplitude,asymmetric intensity gradient amplitude,and bi-objective hologram through the non-local holographic imaging theory that considers the acoustic coupling of structural units in *** taking into account the self-radiation and mutual radiation between many small units on a plate of well-designed thickness,as well as the transmission through the plate's apertures,we can effectively regulate the sound field behind the *** demonstrate the effectiveness of our approach through numerical simulations and experiments,showcasing a circle,a black hole,and a bi-objective with a circle and a square ***,the acoustic black hole hologram precisely reconstructs the intensity gradient distribution at two bright *** non-local holographic imaging theory is valuable for the fine-intensity regulation of the sound field and is expected to be applied in ultrasound diagnosis and treatment,medical imaging,and other fields.

关键词： acoustic holograms non-local interactions fine intensity modulation acoustic metasurfaces

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Coupled CFD-DEM Numerical Simulation of the Interaction of a Flow-Transported Rag with a Solid Cylinder

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Fluid Dynamics & Materials Processing 2024年第7期20卷 1593-1609页

作者： Yun Ren Lianzheng Zhao Xiaofan mo Shuihua Zheng Youdong Yang Zhijiang College Zhejiang University of TechnologyShaoxing312030China College of Mechanical Engineering Zhejiang University of TechnologyHangzhou310032China

A coupled Computational Fluid Dynamics-Discrete Element Method(CFD-DEM)approach is used to calculate the interaction of a flexible rag transported by a fluid current with a fixed solid *** specifically a hybrid Eulerian-Lagrangian approach is used with the rag being modeled as a set of interconnected *** influence of various parameters is considered,namely the inlet velocity(1.5,2.0,and 2.5 m/s,respectively),the angle formed by the initially straight rag with the flow direction(45°,60°and 90°,respectively),and the inlet position(90,100,and 110 mm,respectively).The results show that the flow rate has a significant impact on the permeability of the *** higher the flow rate,the higher the permeability and the rag speed *** angle has a minor effect on rag permeability,with 45°being the most favorable angle for *** inlet position has a small impact on rag permeability,while reducing the initial distance between the rag an the cylinder makes it easier for rags to pass through.

关键词： Rag flow around cylinder flow characteristics numerical simulation

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Precise immobilization of metal single atoms into a porphyrinic metal-organic framework for an efficient alkene hydrosilylation

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Nano Research 2024年第7期17卷 5914-5921页

作者： Chun-Ying Chen Qi-Jie mo Fu-Zhen Li Hai-Li Song Li Zhang moE Laboratory of Bioinorganic and Synthetic Chemistry Lehn Institute of Functional MaterialsSchool of ChemistrySun Yat-Sen UniversityGuangzhou 510006China

Alkene hydrosilylation is one of the most concise and atom-economical methods to synthesize organosilicon ***,we reported the precise immobilization of metal single atoms(M-SAs;M=Ru,Rh,Ir,Pd,Pt,and Au)into a porphyrinic metalorganic framework(moF)of PCN-222(PCN=porous coordination network),and then applied the resultant moF composites of M-SAs@PCN-222 to alkene *** solvent-free conditions,Pt-SAs@PCN-222 displayed an especially high catalytic efficiency with the turnover frequency up to 119 s−1 and the maximum turnover number of 906,250 at room *** and theoretical studies revealed that there existed strong interactions between Pt-SAs@PCN-222 and the substrates,which helped to condense the substrates in the cavities of the porous *** density functional theory calculations and molecular dynamics simulations disclosed that PCN-222 could transfer electrons to Pt-SAs to enhance the silane oxidative addition and drive the reaction to proceed smoothly via Chalk–Harrod pathway.

关键词： alkene hydrosilylation single atom catalysts metal-organic frameworks precision chemistry synergistic catalysis

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Impact of oxaliplatin and trastuzumab combination therapy on tumor markers and T lymphocyte subsets for advanced gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第9期16卷 3905-3912页

作者： Cheng-Wan Zheng Yun-mo Yang Hui Yang Department of Thyroid Surgery The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

BACKGROUND Advanced gastric cancer(AGC)remains a challenging malignancy with poor *** combination of oxaliplatin and trastuzumab has shown promising results in AGC *** study aimed to investigate the effects of oxaliplatin and trastuzumab combination therapy on serum tumor markers and T lymphocyte subsets in patients with AGC and to explore their potential as predictive biomarkers for treatment *** To investigate the impact of oxaliplatin and trastuzumab combination therapy on serum markers and T cell subsets in patients with *** This prospective study enrolled 60 patients with *** patients received oxaliplatin(130 mg/m^(2),every 3 weeks)and trastuzumab(8 mg/kg loading dose,followed by 6 mg/kg every 3 weeks)for six *** carcinoembryonic antigen(CEA),cancer antigen 19-9(CA19-9),and cancer antigen 72-4(CA72-4)were measured before and after treatment.T-lymphocyte subsets,including CD3+,CD4+,CD8+,and CD4+/CD8+ratios,were also *** clinical response was assessed using the Response Evaluation Criteria in Solid Tumors version *** After six cycles of treatment,the CEA,CA19-9,and CA72-4 serum levels significantly decreased compared to baseline levels(Pmor markers(≥50%reduction)and a higher increase in CD4+/CD8+ratio(≥1.5-fold)showed better clinical response rates(Pmor marker levels and modulated T lymphocyte subsets in patients with *** therapy not only has a direct antitumor effect,but also enhances the immune response in patients with *** tumor markers and T lymphocyte subsets may serve as potential predictive biomarkers for treatment respon

关键词： Advanced gastric cancer Oxaliplatin Trastuzumab Serum tumor markers T lymphocyte subsets Predictive biomarkers

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The effect of friction block hole configurations on the brake tribological performance of high-speed trains

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Friction 2024年第10期12卷 2241-2258页

作者： Yuanke WU Wei CHEN Youguang ZHU Zaiyu XIANG Honghua QIAN Jiliang mo Zhongrong ZHOU Tribology Research Institute School of Mechanical EngineeringSouthwest Jiaotong UniversityChengdu 610031China China Railway Engineering Equipment Group Co. Ltd.Zhengzhou 450016China

Three triangular friction block configurations are commonly employed in high-speed train brake systems,namely,unperforated,perforated configuration with one circular hole,and perforated with three circular *** this study,we adopted these friction block types to investigate the effect of perforated friction block configurations on the brake performance of high-speed trains based on a self-developed brake test *** results indicate the significant impact of the number of the holes on the wear behavior,temperature distribution,and vibration characteristics of the brake *** friction surface of the unperforated block is covered by wear debris,while the perforated blocks produce less wear ***,the one-hole block exhibits a more uniform temperature distribution and better vibration behavior than that with three *** friction brake is a dynamic process,during which separation and attachment between the pad and disc alternatively occur,and the perforated structure on the friction block can both trap and expel the wear debris.

关键词： high-speed train block brake performance wear debris flow

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An efficient labeled memory system for learned indexes

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Fundamental Research 2024年第3期4卷 651-659页

作者： Yuxuan mo Jingnan Jia Pengfei Li Yu Hua Huazhong University of Science and Technology Wuhan 430074China

The appearance and wide use of memory hardware bring significant changes to the conventional vertical memory hierarchy that fails to handle contentions for shared hardware resources and expensive data *** deal with these problems,existing schemes have to rely on inefficient scheduling strategies that also cause extra temporal,spatial and bandwidth *** on the insights that the shared hardware resources trend to be uniformly and hierarchically offered to the requests for co-located applications in memory systems,we present an efficient abstraction of memory hierarchies,called Label,which is used to establish the connection between the application layer and underlying hardware *** on labels,our paper proposes LaMem,a labeled,resource-isolated and cross-tiered memory system by leveraging the way-based partitioning technique for shared resources to guarantee QoS demands of applications,while supporting fast and low-overhead cache repartitioning ***,we customize LaMem for the learned index that fundamentally replaces storage structures with computation models as a case study to verify the applicability of *** results demonstrate the efficiency and efficacy of LaMem.

关键词： Heterogeneous memory system Cache hierarchy Data movement Resource contention Learned index

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Correlations of baryon and charge stopping in heavy ion collisions

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Chinese Physics C 2024年第4期48卷 89-94页

作者：吕文棣李洋李子阳马荣荣唐泽波 Prithwish Tribedy Chun yuen Tsang 许长补查王妹 State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Physics Department Brookhaven National LaboratoryUptonNY 11973USA Department of Physics Kent State UniversityKentOH 44242USA

Baryon numbers are theorized to be carried by valence quarks in the standard QCD picture of the baryon *** theory proposed an alternative baryon number carrier,a non-perturbative Y-shaped configuration of the gluon field,called the baryon junction in the ***,neither of these theories has been verified ***,searching for the baryon junction by investigating the correlation of net-charge and net-baryon yields at midrapidity in heavy-ion collisions has been *** paper presents studies of such correlations in collisions of various heavy ions from oxygen to uranium with the UrQMD monte Carlo *** UrQMD model implements valence quark transport as the primary means of charge and baryon stopping at *** studies are also conducted for isobaric ^(96)_(40)Zr+^(96)_(40)Zr and ^(96)_(44)Ru+^(96)_(44)Ru *** found a universal trend of charge stopping with respect to baryon stopping and discovered that the charge stopping is always greater than the baryon *** study provides a model baseline in valence quark transport for what is expected in net-charge and net-baryon yields at the midrapidity of relativistic heavy-ion collisions.

关键词： baryon junction baryon number carrier baryon stopping relativistic heavy ion collisions

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Reconstruction using artificial intelligence,a promising way to explore the cosmic web

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Science China(Physics,Mechanics & Astronomy) 2024年第1期67卷 179-179页

作者： Houjun mo Department of Astronomy University of MassachusettsAmherst MA 01003USA

One of the most important goals in modern cosmology is to understand the large-scale mass distribution of the universe(the cosmic web),and how galaxies form and evolve in the ecosystem of the cosmic *** this is done by large redshift surveys of galaxies,which can be used to trace the large-scale structure and to sample the properties of galaxies.

关键词： galaxies cosmic universe

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Bioinspired Closed-loop CPG-based Control of a Robotic Manta for Autonomous Swimming

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Journal of Bionic Engineering 2024年第1期21卷 177-191页

作者： Yiwei Hao Yonghui Cao Yingzhuo Cao Xiong mo Qiaogao Huang Lei Gong Guang Pan Yong Cao School of Marine Science and Technology Northwestern Polytechnical UniversityXi'an 710072China Unmanned Vehicle Innovation Center Ningbo Institute of NPUNingbo 315103China Key Laboratory of Unmanned Underwater Vehicle Technology of Ministry of Industry and Information Technology Xi'an 710072China

Fish in nature exhibit a variety of swimming modes such as forward swimming,backward swimming,turning,pitching,etc.,enabling them to swim in complex scenes such as coral *** is still difficult for a robotic fish to swim autonomously in a confined area as a real ***,we develop an untethered robotic manta as an experimental platform,which consists of two flexible pectoral fins and a tail fin,with three infrared sensors installed on the front,left,and right sides of the head to sense the surrounding *** generate multiple swimming modes of the robotic manta and online switching of different modes,we design a closed-loop Central Pattern Generator(CPG)controller based on distance information and use a combination of phase difference and amplitude of the CPG model to achieve stable and rapid adjustment of yaw *** verify the autonomous swimming ability of the robotic manta in complex scenes,we design an experimental scenario with a concave *** experimental results show that the robotic manta can achieve forward swimming,backward swimming,in situ turning within the concave obstacle,and finally exit from the area safely while relying on the perception of external obstacles,which can provide insight into the autonomous exploration of complex scenes by the biomimetic robotic ***,the swimming ability of the robotic manta is verified by field tests.

关键词： Biomimetic robotic manta Central Pattern Generator Closed-loop control Backward swimming

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Coupling WO_(3-x) dots-encapsulated metal-organic frameworks and template-free branched polymerization for dual signal-amplified electrochemiluminescence biosensing

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Chinese Chemical Letters 2024年第4期35卷 469-474页

作者： Fei Yin Erli Yang Xue Ge Qian Sun Fan mo Guoqiu Wu Yanfei Shen Medical School Southeast UniversityNanjing 210009China Center of Clinical Laboratory Medicine Zhongda HospitalSoutheast UniversityNanjing 210009China Jiangsu Provincial Key Laboratory of Critical Care Medicine Southeast UniversityNanjing 210009China

Developing accurate and sensitive DNA methyltransferase(MTase) analysis methods is essential for early clinical diagnosis and development of antimicrobial drug targets. In this work, by coupling WO_(3-x) dotsencapsulated metal-organic frameworks(moFs) as co-reactants and terminal deoxynucleotidyl transferase(Td T)-mediated template-free branched polymerization, a dual signal-amplified electrochemiluminescent(ECL) biosensor was constructed to detect DNA adenine methylation(Dam) MTase. The employment of WO_(3-x) dots-encapsulated moFs(i.e., NH_(2)-UIO66@WO_(3-x) ) was not only beneficial for biomolecule conjugation because of the abundant amino groups but also led to a 7-fold enhanced ECL response due to the increased loading of WO_(3-x). moreover, Td T-mediated template-free branched polymerization promoted the capture of ECL emitters on the electrode surface, achieving 20-fold enhanced signal amplification. The presented ECL biosensor demonstrated a low detection limit of 2.4 × 10^(-4)U/m L, and displayed high reliability for the detection of Dam MTase in both spiked human serum and E. coli cell samples, and for the screening of potential inhibitors. This study opens a new avenue for designing a dual signal amplificationbased ECL bioassay for Dam MTase and screening inhibitors in the fields of clinical diagnosis and drug development.

关键词： Dual signal-amplified electrochemiluminescence WO_(3-x)dots moFs Template-free branched polymerization DNA methyltransferase

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