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原发灶切除+化疗与单独化疗治疗存在无症状、同时性、不可切除转移灶的结直肠癌患者的疗效对比--一项随机临床试验(jCOG1007;iPACS)

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结直肠肛门外科 2021年第2期27卷 158-160页

作者：俞少俊 KANEMITSU Y SHITARA K mizusawa j 浙江大学医学院附属第二医院大肠外科浙江杭州310000 不详

目的:关于在原发灶切除术(primary tumor resection,PTR)后进行化疗能否改善存在无症状的原发灶及同时性、不可切除转移灶的结直肠癌患者的生存情况,目前仍有争议。方法:本试验为关于PTR后进行化疗对比单独化疗治疗结直肠癌患者总生存(o... 详细信息

目的:关于在原发灶切除术(primary tumor resection,PTR)后进行化疗能否改善存在无症状的原发灶及同时性、不可切除转移灶的结直肠癌患者的生存情况,目前仍有争议。方法:本试验为关于PTR后进行化疗对比单独化疗治疗结直肠癌患者总生存(overall survival,OS)情况的Ⅲ期随机研究,入组患者(Ⅳ期)存在无症状的不可切除的转移灶,转移灶位于肝、肺、远处淋巴结或腹膜,数量为3个及以下。所采用的化疗方案在入组前已决定,包括mFOLFOX6+贝伐珠单抗或者CapeOX+贝伐珠单抗。主要研究终点是意向治疗人群的OS。

关键词：贝伐珠单抗随机临床试验结直肠癌患者随机研究不可切除无症状同时性原发灶切除

Error field penetration in j-TEXT tokamak based on two-fluid drift-MHD model

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Chinese Physics B 2024年第4期33卷 545-551页

作者：王文徐涛张仪 the j-TEXT team State Key Laboratory of Advanced Electromagnetic Technology International Joint Research Laboratory of Magnetic Confinement Fusion and Plasma PhysicsSchool of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhan 430074China

An externally generated resonant magnetic perturbation can induce complex non-ideal MHD responses in their resonant *** have studied the plasma responses using Fitzpatrick's improved two-fluid model and program *** calculated the error field penetration threshold for *** addition,we find that the island width increases slightly as the error field amplitude increases when the error field amplitude is below the critical penetration ***,the island width suddenly jumps to a large value because the shielding effect of the plasma against the error field disappears after the *** scanning the natural mode frequency,we find that the shielding effect of the plasma decreases as the natural mode frequency ***,we obtain the m/n=2/1 penetration threshold scaling on density and temperature.

关键词： plasma responses drift-MHD model error field penetration

Storing Freshwater Versus Storing Electricity in Power Systems with High Freshwater Electric Demand

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journal of Modern Power Systems and Clean Energy 2024年第2期12卷 323-333页

作者： Mubarak j.Al-Mubarak Antonio j.Conejo Department of Electrical and Computer Engineering The Ohio State UniversityColumbusOHUSA Department of Electrical Engineering Kuwait UniversityP.O.Box 5969Safat 13060Kuwait Department of Integrated Systems Engineering and the Department of Electrical and Computer Engineering The Ohio State UniversityColumbusOH 43210USA IEEE

We consider a power system whose electric demand pertaining to freshwater production is high(high freshwater electric demand),as in the Middle East,and investigate the tradeoff of storing freshwater in tanks versus storing electricity in batteries at the day-ahead operation *** storing freshwater and storing electricity increase the actual electric demand at valley hours and decrease it at peak hours,which is generally beneficial in term of cost and ***,to what extent?We analyze this question considering three power systems with different generation-mix configurations,i.e.,a thermal-dominated mix,a renewable-dominated one,and a fully renewable *** generation-mix configurations are inspired by how power systems may evolve in different countries in the Middle *** production uncertainty is compactly modeled using chance *** draw conclusions on how both storage facilities(freshwater and electricity)complement each other to render an optimal operation of the power system.

关键词： Power system operation freshwater production and transportation coordination day-ahead scheduling

S-1与顺铂新辅助化疗后D2并腹主动脉旁淋巴结清扫治疗腹主动脉旁淋巴结转移胃癌

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消化肿瘤杂志（电子版） 2014年第4期6卷 196-196页

作者： Tsuburaya A mizusawa j Tanaka Y 吴晖不详

背景合并胃周或腹主动脉旁淋巴结广泛转移的局部进展期胃癌是典型的不可切除胃癌,预后不良。目的本研究探究S-1+顺铂化疗后行胃周并腹主动脉旁淋巴结清扫治疗腹主动脉旁淋巴结转移胃癌患者的安全性及有效性。方法合并腹腔动脉及其分支... 详细信息

背景合并胃周或腹主动脉旁淋巴结广泛转移的局部进展期胃癌是典型的不可切除胃癌,预后不良。目的本研究探究S-1+顺铂化疗后行胃周并腹主动脉旁淋巴结清扫治疗腹主动脉旁淋巴结转移胃癌患者的安全性及有效性。方法合并腹腔动脉及其分支周围淋巴结肿大转移和/或腹主动脉旁淋巴结转移的胃癌患者,接受23周期(每28天重复)的S-1+顺铂化疗,而后接受根治性D2+腹主动脉旁淋巴结清扫(PAND)术。观察的主要终点为原发肿瘤无切缘残留(R0)切除率。目标样本量为50例,单侧检验α值及β值分别为0.105、0.2。R0的期望切除率为65%,临界值为50%。

关键词：淋巴结淋巴组织腹主动脉主动脉腹部 S-1 新辅助化疗