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Association between Premenstrual Dysphoric Disorder and Systemic Lupus Erythematosus: Exacerbation of Major Depression Symptoms?

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Open Journal of Rheumatology and Autoimmune Diseases 2013年第4期3卷 209-215页

作者： Sílvia Fernanda Lima de Moura Cal Lorena Cal Alonso Amanda Galvao de Almeida mittermayer barreto santiago Ângela Miranda-Scippa Medicine and Human Health Post-Graduation Program Fundacao Bahiana para o Desenvolvimento das CiênciasEscola Bahiana de Medicina e Saúde PúblicaBahiaBrazil Medicine Graduation Program Faculdade de Tecnologia e CiênciasBahiaBrazil Department of Psychiatry and Laboratório Interdisciplinar de Neurociências Clínicas(LiNC) Universidade Federal de Sao PauloSao PauloBrazil Medicine and Human Health Post-Graduation Program Fundacao Bahiana Para o Desenvolvimento das CiênciasEscola Bahiana de Medicina e Saúde PúblicaBahiaBrazil Department of Neuroscience and Mental Health Universida de Federal da BahiaBahiaBrazil

Introduction: Systemic Lupus Erythematosus (SLE) usually presents neuropsychiatric manifestations, such as psychosis, convulsion, mood disorder and chronic headache, with mood disorder being the most prevalent. It is also known that other psychiatric disorders and menstrual cycle disorders are frequent in SLE. The aim of this study was to describe for the first time the frequency of premenstrual dysphoric disorder in patients with SLE diagnosis, and its association with depression and anxiety. Material and Methods: An evaluation was made of 62 (sixty-two) patients with diagnosis of SLE, based on the American College of Rheumatology criteria, who received follow-up care at an ambulatory reference center. The patients were submitted to a sociodemographic evaluation questionnaire, upon which the Mini International Neuropsychiatric Interview (MINI PLUS), Brazilian Version 5.0.0, was used to evaluate the diagnosis. Results: Twenty (32%) patients were found to have premenstrual dysphoric disorder, and there was a statistically significant association with major depression (p = 0.010), but no statistical significance was found with dysthymia (p = 0.063) or anxiety (p = 0.223). Conclusions: The frequency of premenstrual dysphoric disorder (PMDD) in patients with SLE was high, as well as the frequency of major depression in this group. There was an association between these two disorders.

关键词： Systemic Lupus Erythematous Depression Anxiety Premenstrual Dysphoric Disorder Premenstrual Syndrome

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The influence of porosity on tablet subdivision

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Particuology 2020年第6期18卷 192-196页

作者： Maira T.Teixeira Livia L.Sa-barreto Izabel C.Silva Tais Gratieri Guilherme M.Gelfuso Ricardo N.Marreto Mariana Landin Marcilio Cunha-Filho Laboratory of Food Drugs and Cosmetics(LTMAC)University of Brasilia(UnB)70910-900 BrasiliaDFBrazil Laboratory of Nanosystems and Drug Delivery Devices(NanoSYS) Federal University of GoiasGoianiaGO.Brazil Departamento de Farmacologia Farmacia y Tecnologia Farmaceutica1+D Farma Group(Gl-1645)Universidade de Santiago de CompostelaSpain

A tablet microstructure,especially the porosity,is a crucial parameter that influences the mechanical ***,tablet subdivisions were studied as a functi on of tablet *** tablets were manufactured in the presenee of different diluents,namely microcrystalline cellulose,LudipressR,or lactose ***,the add让ion of Camphor was investigated,which was thereafter sublimated with a view of obtaining tablets having varying degrees of *** assays were corre lated to the subdivision performs *** increase in porosity reduced the hardness and increased the tablet friability,adversely impacting the *** all the excipients,an increase in relative porosity>90%represented the threshold level from which an inadequate subdivision *** in crease in tablet porosity led to a reduction in mechanical resista nee,which,combined with a heterogeneous and disc on tinuous distribution of pores within the matrix,resulted in poor subdivision *** trolling tablet porosity is an important consideration when designing tablets having a subdivision purpose.

关键词： Tablet subdivision Porosity Mass variation Mass loss Friability Hardness

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Ubuntu： Alterity as a Perspective for Peace

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Journal of Sociology Study 2015年第1期5卷 53-59页

作者： Flora Strozenberg Willis santiago Guerra Filho Luiz Otavio Ferreira barreto Leite Edna RaquelSantos Hogemann Milanna Nagib Hellen Cristina Silva de Oliveira Matheus Novais da Silva AnaCarolina Antao The Federal University of State of Rio de Janeiro Brazil

This paper looks for deepening the connections among peace, intercultural dialogue, and communalism in the light of Ubuntu, an ethical concept that emphasizes the alliances constructed between people and the relations established by them, and is seen as fundamental to the African thought of the groups that adopt Bantu languages. It develops an original exercise in diatopical hermeneutics—-a methodology proposed by Raimon Panikkar, taking as the main goal to approach the Western ethical and political thought to the epistemic and ontological category of Ubuntu, recognized in the Zulu maxim umuntu ngumuntu ngabantu (a person is a person through other persons). It chooses as the basis of such study some contemporary thinkers as Lévinas, Bauman, Ramose, Chuwa, Kunene, and Nussbaum, who show a common concern with reverting a context of war and disregard of the integrity of human beings, connected to an ethics of alterity, zealous of the values of conviviality and respect for the cultural differences. It reveals the political dimension of Ubuntu and the impacts of this conception on the process of facing the problems of human rights in post Apartheid South Africa. Grounded on such transdisciplinary reflexion, it tries to point through a path to the implementation of policies for peace based on interculturality and communalism within different cultures.

关键词：异性平视文化差异政治思想多元文化道德诠释学本体论

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