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Gastric adenocarcinoma of the fundic gland(chief cell-predominant type): A review of endoscopic and clinicopathological features

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World Journal of Gastroenterology 2016年第48期22卷 10523-10531页

作者： Masaki Miyazawa mitsuru Matsuda Masaaki Yano Yasumasa Hara Fumitaka Arihara Yosuke Horita Koichiro Matsuda Akito Sakai Yatsugi Noda Department of Internal Medicine Toyama Prefectural Central Hospital

Gastric adenocarcinoma of the fundic gland(chief cellpredominant type, GA-FG-CCP) is a rare variant of welldifferentiated adenocarcinoma, and has been proposed to be a novel disease entity. GA-FG-CCP originates from the gastric mucosa of the fundic gland region without chronic gastritis or intestinal metaplasia. The majority of GA-FG-CCPs exhibit either a submucosal tumor-like superficial elevated shape or a flat shape on macroscopic examination. Narrow-band imaging with endoscopic magnification may reveal a regular or an irregular microvascular pattern, depending on the degree of tumor exposure to the mucosal surface. Pathological analysis of GA-FG-CCPs is characterized by a high frequency of submucosal invasion, rare occurrences of lymphatic and venous invasion, and low-grade malignancy. Detection of diffuse positivity for pepsinogen-I by immunohistochemistry is specific for GA-FG-CCP. Careful endoscopic examination and detailed pathological evaluation are essential for early and accurate diagnosis of GA-FG-CCP. Nearly all GA-FG-CCPs are treated by endoscopic resection due to their small tumor size and low risk of recurrence or metastasis.

关键词： Narrow-band imaging Pepsinogen-I Fundic gland Gastric adenocarcinoma Chief cell

Pulsed field magnetization of multiple bulks used as field pole of a high-temperature superconducting rotating machine

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Superconductivity 2023年第1期5卷 63-68页

作者： Antomne A.Caunes Mizuki Tsuchiya Hayato Imamichi Nagisa Kawasumi mitsuru Izumi Tetsuya Ida Tokyo University of Marine Science and Technology 4-5-7KonanMinato-kuTokyo 108-8477Japan National Institute of Technology Toba College1-1Ikegami-choTobaMie 517-8501Japan

An array of three GdBa_(2)Cu_(3)O_(7‐δ)bulk high‐temperature superconductors(HTS)that mimic the field pole of a high‐power superconducting motor had been magnetized by pulsed field magnetization(PFM)while cooled by liquid *** bulk array was magnetized by a passive PFM technique using three vortex‐type coils placed over each individual bulk and connected in *** trapped magnetic flux density distribution was comparable to the distribution obtained with more traditional quasi‐static magnetization such as field‐*** suggests that the use of PFM technique on arrays of HTS bulks is *** has also been performed using each coil individually,to magnetize each bulk *** magnetization sequences showed a maximum reduction of the peak trapped magnetic flux density of 12%due to the demagnetization effect of the magnetization sequence,while the trapped magnetization distribution was improved.

关键词： Pulsed field magnetization HTS bulk Bulk HTS field pole Multiple bulks array Large field pole Superconducting rotating machines

Endoscopic resection for residual lesion of metastatic gastric cancer:A case report

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World Journal of Clinical Cases 2019年第4期7卷 482-488页

作者： Kaori Hayashi Sho Suzuki Hisatomo Ikehara Hiroaki Okuno Akira Irie mitsuru Esaki Chika Kusano Takuji Gotoda Mitsuhiko moriyama Division of Gastroenterology and Hepatology Department of Medicine Nihon University School of Medicine

BACKGROUND Chemotherapy is a standard strategy for stage IV gastric cancer ***, some cases cannot undergo conversion surgery because of their frailty,even if the patients had response to chemotherapy. For these patients, local tumor progression is a problem. We report here the case of a patient whose residual gastric cancer was resected through endoscopic submucosal dissection(ESD)after concomitant chemotherapy for metastatic gastric *** SUMMARY An 85-year-old male complained of difficulty swallowing, and examination revealed gastric cancer with multiple liver metastases. Although he received concomitant chemotherapy, a residual tumor was observed in the primary lesion while the metastatic lesions disappeared completely. Conversion surgery was considered optional treatment; however, he could not undergo that because of advanced age and comorbidities. Thus, we performed ESD to treat the residual tumor. As a result, we resected the residual lesion completely. The patient has been alive for 29 mo since ESD, without *** We achieved local control using ESD, and these findings may provide therapeutic improvements both in local control and patient survival outcomes.

关键词： Gastric cancer Liver metastases Conversion Endoscopic submucosal dissection Chemotherapy Case report

h-线敏感光致产碱剂PNCDP的合成与表征

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影像科学与光化学 2009年第2期27卷 95-102页

作者：刘金刚 mitsuru Ueda 中国科学院化学研究所高技术材料实验室北京100190 东京工业大学有机高分子物质专攻

设计并合成了一种对高压汞灯发射光谱中的h-线(405 nm)敏感的新型光致产碱剂(PBG)——N-{[(5-哌啶-2-硝基苄基)氧]-羰基}-2,6-二甲基哌啶(PNCDP).通过红外(IR)、核磁(NMR)以及元素分析对PNCDP的结构进行了表征.紫外-可见光谱(UV-Vis)测... 详细信息

设计并合成了一种对高压汞灯发射光谱中的h-线(405 nm)敏感的新型光致产碱剂(PBG)——N-{[(5-哌啶-2-硝基苄基)氧]-羰基}-2,6-二甲基哌啶(PNCDP).通过红外(IR)、核磁(NMR)以及元素分析对PNCDP的结构进行了表征.紫外-可见光谱(UV-Vis)测试结果表明,与传统的i-线(365 nm)敏感PBG——N-{[(4,5-二甲氧基-2-硝基苄基)氧]-羰基}-2,6-二甲基哌啶(DNCDP)相比,PNCDP的最大紫外吸收波长为395.5 nm,较DNCDP红移了52.5 nm.初步光刻实验表明,PNCDP对h-线具有较好的敏感度.

关键词：光致产碱剂 h-线聚酰亚胺光致抗蚀剂

Efficiency of soil and water conservation practices in different agro-ecological environments in the Upper Blue Nile Basin of Ethiopia

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Journal of Arid Land 2018年第2期10卷 249-263页

作者： Dagnenet SULTAN Atsushi TSUNEKAWA Nigussie HAREGEWEYN Enyew ADGO mitsuru TSUBO Derege T MESHESHA Tsugiyuki MASUNAGA Dagnachew AKLOG Ayele A FENTA Kindiye EBABU The United Graduate School of Agricultural Sciences Tottori University School of Civil and Water Resource Engineering Institute of Technology Bahir Dar University Arid Land Research Center Tottori University International Platform for Dryland Research and Education Tottori University Department of Natural Resources Management Bahir Dar University Institute for Soil Climate and Water Agricultural Research Council Faculty of Life and Environmental Science Shimane University Center for International Affairs Tottori University

In developing countries such as Ethiopia, research to develop and promote soil and water conservation practices rarely addressed regional diversity. Using a water-balance approach in this study, we used runoff plots from three sites, each representing a different agro-ecological environment, e.g., high, mid and low in both elevation and rainfall, in the Upper Blue Nile Basin of Ethiopia to examine the runoff response and runoff conservation efficiency of a range of different soil and water conservation measures and their impacts on soil moisture. The plots at each site represented common land use types（cultivated vs. non-agricultural land use types） and slopes（gentle and steep）. Seasonal runoff from control plots in the highlands ranged 214–560 versus 253–475 mm at midlands and 119–200 mm at lowlands. The three soil and water conservation techniques applied in cultivated land increased runoff conservation efficiency by 32% to 51%, depending on the site. At the moist subtropical site in a highland region, soil and water conservation increased soil moisture enough to potentially cause waterlogging, which was absent at the lowrainfall sites. Soil bunds combined with Vetiveria zizanioides grass in cultivated land and short trenches in grassland conserved the most runoff（51% and 55%, respectively）. Runoff responses showed high spatial variation within and between land use types, causing high variation in soil and water conservation efficiency. Our results highlight the need to understand the role of the agro-ecological environment in the success of soil and water conservation measures to control runoff and hydrological dynamics. This understanding will support policy development to promote the adoption of suitable techniques that can be tested at other locations with similar soil, climatic, and topographic conditions.

关键词： agro-ecology drought-prone runoff coefficient runoff conservation efficiency Ethiopia

A case of obstructive azoospermia secondary to genitourinary tract infection caused by a prostatic utricle cyst

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Asian Journal of Andrology 2022年第5期24卷 558-559页

作者： Tomoki Saito mitsuru Komeya Kimitsugu Usui Shinnosuke Kuroda Teppei Takeshima Kunitomo Takashima Mario Ikeda Yoshihito Kondo Yasushi Yumura Department of Urology Yokohama City University Medical Center4-57 Urafune-choMinami-kuYokohama CityKanagawa 232-0024Japan Department of Urology Yokohama City University Graduate School of Medicine3-9 FukuuraKanazawa-kuYokohama CityKanagawa 236-0004Japan Ebina Ladies Clinic 3-3-1 ChuoEbina CityKanagawa 243-0432Japan

Dear Editor,Obstructive azoospermia(OA)is defined as the absence of spermatozoa in the sediment of a centrifuged sample of ejaculate and is usually caused by an obstruction anywhere along the posttesticular *** is diagnosed in 20%–40%of men with *** OA may be acquired congenitally,such as in Young’s syndrome that presents with bilateral vas deferens abnormalities,it commonly develops as a sequela of prostatic and ejaculatory duct cysts,childhood inguinal hernias,epididymitis,and vasectomy.

关键词： prostatic azoospermia urinary

Rowing Exercise for Elderly Health

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Rowing Exercise for Elderly Health

New simulation model for bone formation markers in osteoporosis patients treated with once-weekly teriparatide

2015第十届全国体育科学大会

作者： mitsuru Higuchi Waseda University

Aerobic exercise is recommended for the prevention of lifestyle-relateddiseases, while resistance exercise is recommended for the prevention of osteoporosisandsarcopenia. Both types of exercise are important in helping elderly people tomaintain quality of life. Rowing is one of the oldest sports in the world and it offersa combination of both aerobic and resistance exercise. Because rowing is practicedon a seat, less impact is placed upon the knee joints, making it safe for elderlypeople even if they are categorized as overweight or obese. Elderly rowershavehigher cardiorespiratory fitness（CRF） and a lower risk of coronary heart diseasescompared with age-matched untrained people. The bone mineral density and musclesize in rowers are also greater than in untrained people. After 6-month exercisetraining in elderly men using a rowing ergometer, CRF and muscle size increasedand the risk of lifestyle-related diseases also improved. An indoor rowing ergometerhas been developed which offers a safe and easy tool for exercise in elderly people,even those who are wheelchair-bound. Therefore, rowing could offer a beneficialcombination of aerobic and resistance exercises for achieving an active life in theelderly population.

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来源： cnki会议评论

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Bone Research 2014年第4期2卷 252-258页

作者： Sakae Tanaka Taiji Adachi Tatsuhiko Kuroda Toshitaka Nakamura Masataka Shiraki Toshitsugu Sugimoto Yasuhiro Takeuchi mitsuru Saito John P Bilezikian Department of Orthopaedic Surgery Faculty of MedicineUniversity of TokyoTokyoJapan Department of Biomechanics Institute for Frontier Medical SciencesKyoto UniversityKyotoJapan Medical Affairs Department Asahi Kasei Pharma CorporationTokyoJapan National Center for Global Health and Medicine TokyoJapan Research Institute and Practice for Involutional Diseases NaganoJapan Internal Medicine 1 Shimane University Faculty of MedicineIzumoJapan Toranomon Hospital Endocrine Center TokyoJapan Department of Orthopaedic Surgery Jikei University School of MedicineTokyoJapan Metabolic Bone Diseases Program Division of EndocrinologyDepartment of MedicineCollege of Physicians and SurgeonsColumbia UniversityNew YorkUSA

Daily 20-mg and once-weekly 56.5-mg teriparatide（parathyroid hormone 1–34） treatment regimens increase bone mineral density（BMD） and prevent fractures, but changes in bone turnover markers differ between the two regimens. The aim of the present study was to explain changes in bone turnover markers using once-weekly teriparatide with a simulation model. Temporary increases in bone formation markers and subsequent decreases were observed during once-weekly teriparatide treatment for 72 weeks. These observations support the hypothesis that repeated weekly teriparatide administration stimulates bone remodeling, replacing old bone with new bone and leading to a reduction in the active remodeling surface. A simulation model was developed based on the iterative remodeling cycle that occurs on residual old bone. An increase in bone formation and a subsequent decrease were observed in the preliminary simulation. For each fitted time point, the predicted value was compared to the absolute values of the bone formation and resorption markers and lumbar BMD. The simulation model strongly matched actual changes in bone turnover markers and BMD. This simulation model indicates increased bone formation marker levels in the early stage and a subsequent decrease. It is therefore concluded that remodeling-based bone formation persisted during the entire treatment period with once-weekly teriparatide.

关键词： bone New simulation model for bone formation markers in osteoporosis patients treated with once-weekly teriparatide BMD

NiFe alloy particles doping effect of Gd-Ba-Cu-O bulks processed by a new cold-seeding technology

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Transactions of Nonferrous Metals Society of China 2013年第7期23卷 2042-2046页

作者：周迪帆徐坤 Shogo HARA 李备战 mitsuru IZUMI Department of Marine Electronics and Mechanical Engineering Tokyo University of Marine Science and Technology2-1-6 Etchu-jimaKoto-kuTokyo 135-8533Japan

The process of cold seeding melt growth of GdBa2Cu3Oy （Gd123） bulk superconductors using NdBa2Cu3Oy （Nd123） thin films was reported. In addition, a novel cold seeding concept of combining MgO crystal and buffer pellet was also introduced. The misorientation caused by the lattice mismatch between MgO and Gd123 melt was overcome by choosing suitable heat treatment program and Gd2BaCuO5 （Gd211） content of the buffer pellet. The doping effect of soft ferromagnetic NiFe alloy particles was also reported. The bulk sample with 0.4% （mole fraction） doping amount shows the best performance on the flux trapping. The critical current density is largely enhanced under the external field of 1-2 T, which is promising for large-scale applications. This effect is originated from the substitution of Fe and Ni ions for the Cu sites contributing to magnetic flux pinning.

关键词： high temperature superconductor crystal growth cold seeding chemical doping magnetic flux pinning critical current second peak effect