检索结果-南通市图书馆

Quality-adjusted life years and surgical waiting list:Systematic review of the literature

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2024年第4期16卷 1155-1164页

作者： Roberto de la Plaza Llamas Lorena Ortega Azor Marina Hernández Yuste Ludovica Gorini Raquel Aránzazu latorre-Fragua Daniel Alejandro Díaz Candelas Farah Al Shwely Abduljabar Ignacio Antonio Gemio del Rey Department of General and Digestive Surgery Hospital Universitario de GuadalajaraGuadalajara 19002Spain Department of Surgery Medical and Social SciencesFaculty of Medicine and Health SciencesUniversity of AlcaláAlcaláde Henares 28871MadridSpain

BACKGROUND The quality-adjusted life year(QALY)is a metric that is increasingly used today in the field of health economics to evaluate the value of different medical treatments and *** waiting lists(SWLs)represent a pressing problem in public *** QALY measure has rarely been used in the context of *** would be interesting to know how many QALYs are lost by patients on *** To investigate the relationship between QALYs and SWLs in a systematic review of the scientific *** The study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses *** unlimited search was carried out in PubMed,updated on January 19,*** on the following variables were investigated and analyzed:Specialty,country of study,procedure under study,scale used to measure QALYs,the use of a theoretical or real-life model,objectives of the study and items measured,the economic value assigned to the QALY in the country in question,and the results and conclusions *** Forty-eight articles were selected for the *** data were found regarding QALYs lost on *** specialties in which QALYs were studied the most in relation to the waiting list were urology and general surgery,with 15 articles *** country in which the most studies of QALYs were carried out was the United States(n=21),followed by the United Kingdom(n=9)and Canada(n=7).The most studied procedure was organ transplantation(n=39),including 15 kidney,14 liver,5 heart,4 lung,and 1 ***(n=4),cataract surgery(n=2),bariatric surgery(n=1),mosaicplasty(n=1),and septoplasty(n=1)completed the surgical interventions ***-nine of the models used were theoretical(the most frequently applied being the Markov model,n=34),and nine were *** survey used to measure quality of life in 11 articles was the European Quality of Life-5 dimensions,but in 32 articles the survey was not specified.T

关键词： Quality-adjusted life year Waitlist Quality of life Surgery Systematic review

Carbocysteine as Adjuvant Therapy in Acute Respiratory Tract Infections in Patients without Underlying Chronic Conditions: Systematic Review and Meta-Analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Respiratory Diseases 2024年第2期14卷 39-50页

作者： Myriam Calle Rubio Olga de la Serna Blazquez José Luis R. Martin Manuel Ruiz Cuetos Pulmonology Department Hospital Clínico San Carlos Madrid Spain Department of Medicine School of Medicine Universidad Complutense de Madrid Madrid Spain Instituto de Investigacion Sanitaria del Hospital Clínico San Carlos (IdISSC) Madrid Spain Pediatric Pulmonology Unit Pediatrics Department Hospital Universitario La Paz Madrid Spain Simplifying Research Institute Layos Spain Medical department in ITF Research Pharma S.L.U. Alcobendas Spain

Objective: This study aims to systematically examine the existing evidence regarding the clinical benefits of carbocysteine as an adjunctive treatment in acute bronchopulmonary and otorhinological processes. Design: Systematic review and meta-analysis. Data sources: An electronic search was conducted across PubMed, Cochrane Library, ***, and the European Clinical Trial Register, with the search dated to May 2023. Bibliographic references from other literature reviews and meta-analyses were also reviewed. The search was limited to randomized clinical trials published in any language and year. It was completed by cross-checking the references of the located articles. Methods: Inclusion criteria covered studies assessing systemic or inhaled carbocysteine, regardless of dosing regimen. Concomitant medication use was acceptable if balanced between intervention and control groups. Authors independently extracted data, resolving disagreements through consensus. Methodological quality assessment relied on critical reading of each study. Dichotomous variables were analyzed using odds ratio (OR), and a final effect size was calculated. Statistical significance was established when confidence intervals did not cross the neutral value. Heterogeneity was assessed via the X2 test and I2 index. Results: Out of 318 initially identified studies, 4 met inclusion criteria. The meta-analysis for poor general condition yielded an OR of 0.45 in favor of intervention, p = 0.013, with non-significant heterogeneity. Cough events showed a percentage of 15.8% for carbocysteine vs. 27.2% for placebo. On the seventh day, expectoration rates were 18.37% for carbocysteinevs 33.3% for placebo. Conclusions: The observed clinical benefits align with carbocysteine’s mucoactive and muco-regulatory properties, complemented by anti-inflammatory and antioxidant actions. Carbocysteine stands out among mucolytic agents. In the context of persistent infectious diseases,

关键词： Acute Respiratory Infections Carbocystenine Systematic Review Meta-Analysis

A compact multi-pixel superconducting nanowire single-photon detector array supporting gigabit space-to-ground communications

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第2期13卷 254-266页

作者： Hao Hao Qing-Yuan Zhao Yang-Hui Huang Jie Deng Fan Yang Sai-Ying Ru Zhen Liu Chao Wan Hao Liu Zhi-Jian Li Hua-Bing Wang Xue-Cou Tu la-Bao Zhang Xiao-Qing Jia Xing-Long Wu Jian Chen Lin Kang Pei-Heng Wu Research Institute of Superconductor Electronics(RISE) School of Electronic Science and EngineeringNanjing UniversityNanjingJiangsu 210023China Purple Mountain laboratories NanjingJiangsu 211111China Hefei National laboratory HefeiAnhui 230088China National laboratory of Solid State Microstructures and Department of Physics Nanjing UniversityNanjing 210023China

Classical and quantum space-to-ground communications necessitate highly sensitive receivers capable of extracting information from modulated photons to extend the communication distance from near-earth orbits to deep space *** achieve gigabit data rates while mitigating strong background noise photons and beam drift in a highly attenuated free-space channel,a comprehensive design of a multi-functional detector is *** this study,we present an innovative compact multi-pixel superconducting nanowire single-photon detector array that integrates near-unity detection efficiency(91.6%),high photon counting rate(1.61 Gcps),large dynamic range for resolving different photon numbers(1-24),and four-quadrant position sensing function all within one ***,we have constructed a communication testbed to validate the advantages offered by such an *** 8-PPM(pulse position modulation)format communication experiments,we have achieved an impressive maximum data rate of 1.5 Gbps,demonstrating sensitivities surpassing previous benchmarks at respective *** incorporating photon number information into error correction codes,the receiver can tolerate maximum background noise levels equivalent to 0.8 photons/slot at a data rate of 120 Mbps—showcasing a great potential for daylight operation ***,preliminary beam tracking tests were conducted through open-loop scanning techniques,which revealed clear quantitative dependence indicating sensitivity variations based on beam *** on the device characterizations and communication results,we anticipate that this device architecture,along with its corresponding signal processing and coding techniques,will be applicable in future space-to-ground communication tasks.

关键词： photon supporting correction

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

风级对船舶主推进柴油机加速特性的影响

哈尔滨工程大学学报 2024年第7期45卷 1330-1337页

作者：李兵权丁宇向拉随从标哈尔滨工程大学动力与能源工程学院黑龙江哈尔滨150001

为了研究船舶主推进柴油机在风浪海况下的加速特性,本文以一艘超大型油轮智能示范船为研究对象,利用模块化方法建立了柴油机、推进系统、船舶三自由度运动和风浪干扰综合模型,分别利用柴油机台架实验和实船试航数据对模型进行了验证。... 详细信息

为了研究船舶主推进柴油机在风浪海况下的加速特性,本文以一艘超大型油轮智能示范船为研究对象,利用模块化方法建立了柴油机、推进系统、船舶三自由度运动和风浪干扰综合模型,分别利用柴油机台架实验和实船试航数据对模型进行了验证。通过模拟不同风级下柴油机的加速过程,计算出不同风级下船舶主推进柴油机的运行极限,揭示风浪对推进系统加速性能的影响规律。研究结果表明:随着风级的增加,柴油机加速过程功率裕度越来越小,且风力为8、9、10级时,安全运行极限为:57.4 r/min&18866 kW、51 r/min&14910 kW、48 r/min&13560 kW;风级大小主要影响加速过程增压器效率,对增压器安全性影响较小。本文研究结果可用于指导船舶航行安全设计。

关键词：柴油机船舶推进系统恶劣海况船舶试航试验风级主机加速风浪干扰柴油机运行边界

Adenovirus F40/41 Gastroenteritis-Associated Emphysematous Gastritis:A Case Report

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Infectious Diseases & Immunity 2024年第2期4卷 93-95页

作者： Maulik K.lathiya Abigail T.la Nou Maria E.Linnaus Susan M.Cullinan Emergency Department Mayo Clinic Health SystemEau Claire 54703WIUSA Critical Care Medicine Mayo Clinic Health SystemEau Claire 54703WIUSA General Surgery Department Mayo Clinic Health SystemEau Claire 54703WIUSA

Emphysematous gastritis(EG)is a rare form of gastritis characterized by gastric wall *** is associated with a high mortality *** case report describes a patient with a history of atrial fibrillation treated with apixaban,prior stroke,and schizoaffective disorder who showed epigastric tenderness on ***,no peritonitis signs were recorded,and laboratory values revealed high lactate levels and the presence of adenovirus F40/*** computed tomography scan showed extensive portal venous gas in the left hepatic lobe of the liver,as well as pneumatosis involving the entire stomach,indicating *** diagnosis was histologically confirmed and initially managed medically,which proved inefficacious,necessitating surgical intervention in the form of a laparotomy and esophagojejunostomy with Roux-en-Y *** case report suggests a potential association between EG and adenovirus F40/41–induced gastroenteritis,thereby emphasizing the challenging nature of *** underscores the need for comprehensive research to enhance our understanding of its underlying causes and effective treatment strategies.

关键词： Emphysema Gastritis Human adenovirus F40/41 Immunocompromised

变电站内SF_(6)分解物检测追踪系统设计

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国测试 2024年第3期50卷 144-151页

作者：王建邦喇元南方电网数字电网集团有限公司广东广州510000

六氟化硫(SF_(6))气体分解与泄漏现象日趋严重,给电气设备的绝缘性能带来了严重的负面影响,甚至对电气设备在运行过程中的安全性产生了极大的威胁。为快速有效地对SF_(6)气体的分解物(二氧化硫SO_(2)、硫化氢H_(2)S等)进行检测并定位泄... 详细信息

六氟化硫(SF_(6))气体分解与泄漏现象日趋严重,给电气设备的绝缘性能带来了严重的负面影响,甚至对电气设备在运行过程中的安全性产生了极大的威胁。为快速有效地对SF_(6)气体的分解物(二氧化硫SO_(2)、硫化氢H_(2)S等)进行检测并定位泄露源,该研究基于高级精简指令集计算机(advanced RISC machine,ARM)控制器设计了可以检测以上两种主要有毒气体的电子鼻系统。接着以模拟退火算法为基础,提出气体烟羽追踪方法,旨在解决气体泄露源定位问题。气体浓度检测实验表明,相比MX6商业电子鼻,该文自制的电子鼻系统的气体浓度检测相对误差在0.7×10^(-6)以内,可以有效地检测以上两种有毒气体。此外,考虑到以上气体具有毒性,以乙醇气体为气味源进行了气体烟羽追踪实验。结果表明,该文所提出算法的有效性和实时性较好,平均定位误差只有0.63 m。以上实验证明该设计的电子鼻及模拟退火算法能够满足移动机器人进行SF_(6)分解气体泄漏检测的应用需求。

关键词： SF_(6)分解气体烟羽追踪电子鼻模拟退火算法泄漏检测

Contribution of extracellular vesicles to steatosis-related liver disease and their therapeutic potential

在线全文

学校读者我要写书评

暂无评论

World Journal of Hepatology 2024年第9期16卷 1211-1228页

作者： Margarita Montoya-Buelna Inocencia G Ramirez-Lopez Cesar A San Juan-Garcia Jose J Garcia-Regalado Mariana S Millan-Sanchez Ulises de la Cruz-Mosso Jesse Haramati Ana L Pereira-Suarez Jose Macias-Barragan laboratorio de Inmunología Departamento de FisiologíaUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico Departamento de Ciencias de la Salud Centro Universitario de los VallesUniversidad de GuadalajaraAmeca 46600JaliscoMexico Doctorado en Ciencias Biomédicas Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico laboratorio de Inmunología Departamento de FisiologíaCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico Red de Inmunonutrición y Genómica Nutricional en las Enfermedades Autoinmunes Departamento de NeurocienciasCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico laboratorio de Inmunobiología Departamento de Biología Celular y MolecularCentro Universitario de Ciencias Biológicas y AgropecuariasUniversidad de GuadalajaraZapopan 45200JaliscoMexico Instituto de Investigación en Ciencias Biomédicas Departamento de Microbiología y PatologíaCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico

Extracellular vesicles(EVs)are small particles released by many cell types in different tissues,including the liver,and transfer specific cargo molecules from originating cells to receptor *** process generally culminates in activation of distant cells and inflammation and progression of certain *** global chronic liver disease(CLD)epidemic is estimated at 1.5 billion patients *** and liver cancer are the most common risk factors for ***,hepatitis C and B virus infection and obesity are also highly associated with ***,the etiology of many CLD pathophysiological,cellular,and molecular events are *** in hepatic lipid metabolism can lead to lipotoxicity events that induce EV ***,we aimed to present an overview of EV features,from definition to types and biogenesis,with particular focus on the molecules related to steatosis-related liver disease,diagnosis,and therapy.

关键词： Extracellular vesicles Exosomes Chronic liver disease Hepatocellular carcinoma Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis

1976-2016年普若岗日冰川和流域湖泊变化及其对气候变化的响应

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

气象与环境科学 2024年第2期47卷 54-61页

作者：拉巴拉巴卓玛边多拉珍西藏高原大气环境科学研究所拉萨850001 西藏自治区气候中心拉萨850001

基于藏北地区普若岗日冰川1976-2016年多时相landsat系列卫星影像数据,以及气温、降水量数据,采用ARCGIS空间分析、线性趋势分析、相关分析等方法,研究了普若岗日冰川和流域湖泊面积变化及其对气候变化的响应。结果表明:近41年普若岗日... 详细信息

基于藏北地区普若岗日冰川1976-2016年多时相landsat系列卫星影像数据,以及气温、降水量数据,采用ARCGIS空间分析、线性趋势分析、相关分析等方法,研究了普若岗日冰川和流域湖泊面积变化及其对气候变化的响应。结果表明:近41年普若岗日冰川面积呈显著退缩趋势,41年内冰川面积减少了52.32 km^(2),减小率为12.01%;冰川西北部退缩最为严重,冰川面积减少了12.29 km^(2),减小率为15.77%;且冰川西北部、北部、东部和东南部末端消融显著;其他区域也有不同程度的退缩。流域湖泊面积呈显著增长趋势,共增长了27.17 km^(2),增长率为22.22%;流域气温总体上呈显著增加趋势,平均每10年增加0.48℃;降水量呈不显著上升趋势,平均每10年增加15 mm。降水对冰川和流域湖泊面积影响较小,温度的持续升高是冰川和流域湖泊变化的主要因素。

关键词：普若岗日冰川湖泊面积气候变化

“(你)看/瞧NP多(么)X”的表达功能及形成机制

在线全文

学校读者我要写书评

暂无评论

汉语学习 2024年第5期 55-64页

作者：宁柏慧陈昌来云南民族大学昆明650504 上海师范大学上海200234

感叹性评价构式“(你)看/瞧NP多(么)X”有主观评价、诱使移情、超预期量的表达功能,呈现出(交互)主观性、感叹性的表达特点。构式形式来源于感叹式“多么(们)+A”所辖的不同层级的构式变体,类推、紧缩、形式异变机制起促动作用;构式义... 详细信息

感叹性评价构式“(你)看/瞧NP多(么)X”有主观评价、诱使移情、超预期量的表达功能,呈现出(交互)主观性、感叹性的表达特点。构式形式来源于感叹式“多么(们)+A”所辖的不同层级的构式变体,类推、紧缩、形式异变机制起促动作用;构式义浮现是词项义与构式义互动整合、语境吸收与言者主观认知诱发、动态范畴化与隐喻共同作用的结果。

关键词：感叹评价构式功能特点形成机制

维普期刊数据库博看期刊