检索结果-南通市图书馆

Acta Metallurgica Sinica(English Letters) 2024年第1期37卷 159-168页

作者： Hongyu Zheng Xin Gai Yun Bai Wentao Hou Shujun Li Yulin Hao R.D.K.misra Rui Yang Institute of Metal Research Chinese Academy of SciencesShenyang110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang110016China Nuclear Power Institute of China Chengdu610213China Department of Metallurgical Materialsand Biomedical EngineeringThe University of Texas at El Paso500WUniversity AvenueEl PasoTX79968USA

The electrochemical behavior of Ti-6Al-4v with 1 mm and 16 mm thickness prepared by electron beam powder bed fusion(EB-PBF)was investigated in phosphate buffered *** results showed that EB-PBF Ti-6Al-4v with a larger component size was more resistant to corrosion compared to the smaller component,because of less acicularαʹphase content and moreβphase *** a non-equilibrium phase in the“high-energy state”,αʹphase has a greater susceptibility to corrode and reduces the corrosion resistance of the material,whileβphase improves corrosion resistance of titanium *** results show that the phase composition has a more significant effect on the corrosion performance than the grain size.

关键词： Electron beam powder bed fusion Ti6Al4v alloy Corrosion resistance Component size Polarisation

Friction assisted solid state lap seam welding and additive manufacturing method

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2016年第1期12卷 16-24页

作者： prasad Rao KALvALA Javed AKRAM Mano misra Dept. of Metallurgical Engineering University of Utah

This paper describes results of seam welding of relatively high temperature melting materials, AISI 304, C-Mn steels, Ni-based alloys, CP Cu, CP Ni, Ti6Al4v and relatively low temperature melting material, AA6061. It describes the seam welding of multi-layered similar and dissimilar metallic sheets. The method described and involved advancing a rotating non-consumable rod(CP Mo or AISI 304) toward the upper sheet of a metallic stack clamped under pressure. As soon as the distal end of the rod touched the top portion of the upper metallic sheet, an axial force was applied. After an initial dwell time, the metallic stack moved horizontally relative to the stationery non-consumable rod by a desired length, thereby forming a metallurgical bond between the metallic sheets. Multi-track and multi-metal seam welds of high temperature metallic sheets, AISI 304, C-Mn steel,Nickel-based alloys, Cp Cu, Ti6Al4v and low temperature metallic sheets, AA6061 were obtained. Optical and scanning electron microscopy examination and 180 degree U-bend test indicated that defect free seam welds could be obtained with this method. Tensile- shear testing showed that the seam welds of AISI 304, C-Mn steel, Nickel-based alloy were stronger than the starting base metal counterparts while AA6061 was weaker due to softening. The metallurgical bonding at the interface between the metallic sheets was attributed to localized stick and slip at the interface, dynamic recrystallization and diffusion. The method developed can be used as a means of welding, cladding and additive manufacturing.

关键词： Lap seam welding Friction assisted welding Solid-state welding Cladding Additive manufacturing

Targeting LIF/LIFR signaling in cancer

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2022年第4期9卷 973-980页

作者： Suryavathi viswanadhapalli Kalarickal v.Dileep Kam Y.J.Zhang Hareesh B.Nair ratna K.vadlamudi Department of Obstetrics and Gynecology University of Texas Health San AntonioSan AntonioTX 78229USA Laboratory for Structural Bioinformatics Center for Biosystems Dynamics ResearchRIKENYokohamaKanagawa 230-0045Japan Evestra Inc.San AntonioTX 78245USA Mays Cancer Center University of Texas Health San AntonioSan AntonioTX 78229USA

Leukemia inhibitory factor (LIF), and its receptor (LIFR), are commonly over-expressed in many solid cancers and recent studies have implicated LIF/LIFR axis as a promising clinical target for cancer therapy. LIF/LIFR activate oncogenic signaling pathways including JAK/STAT3 as immediate effectors and MAPK, AKT, mTOR further downstream. LIF/LIFR signaling plays a key role in tumor growth, progression, metastasis, stemness and therapy resistance. Many solid cancers show overexpression of LIF and autocrine stimulation of the LIF/LIFR axis;these are associated with a poorer relapse-free survival. LIF/LIFR signaling also plays a role in modulating multiple immune cell types present in tumor micro environment (TME). Recently, two targeted agents that target LIF (humanized anti-LIF antibody, MSC-1) and LIFR inhibitor (EC359) were under development. Both agents showed effectivity in preclinical models and clinical trials using MSC-1 antibody are in progress. This article reviews the significance of LIF/LIFR pathways and inhibitors that disrupt this process for the treatment of cancer.

关键词： LIF LIFR LIFR inhibitor STAT3 Targeted therapy

Effective platform for the generation of aerosol droplets and application in evaluating the effectiveness of a MEMS-based nanoparticle trapping device

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2009年第6期7卷 471-476页

作者： ratna Tantra Dipak Gohil Peter Cumpson National Physical Laboratory Hampton RoadTeddingtonMiddlesex TW11 0LWUnited Kingdom School of Mechanical and Systems Engineering Newcastle UniversityNewcastle-upon-Tyne NE1 7RUUnited Kingdom

The purpose of this study is two-fold： firstly, the development of a cheap, easy-to-construct and effective nanoparticle generator for testing nanoparticle sensors; secondly, the use of such a generator to test the effectiveness of a sensor device in trapping aerosolised nanoparticles. In this study, we have constructed an effective aerosol generator platform, based on aerosol-assisted chemical vapour deposition technology. Under well-controlled experimental conditions, this platform is capable of depositing aerosolised sodium chloride particles homogeneously on a substrate very effectively. Deposited aerosol droplets were subsequently dried and shown to form nanosized cubic crystals that are free from impurities. This platform was employed to test the effectiveness of a MEMS comb device in the electrostatic trapping of nanoparticles. Upon applying a DC bias （0.5 v） to the MEMS device, results showed an increase in nanoparticle deposition on the surface of the device, due to electrostatic precipitation. The presence of an electric field was shown to affect crystal formation upon drying of the aerosol droplets on the substrate; this caused a blotchy appearance on the SEM image, which was not observed in the absence of electric field.

关键词： Aerosol MEMS sensor Particle generator

Hydrogen trapping and electrochemical corrosion behavior of v–N microalloyed X80 pipeline steels consisting of acicular ferrite and polygonal ferrite

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Iron and Steel Research(International) 2022年第10期29卷 1683-1693页

作者： Ming-ming Wang Xiu-hua Gao Li-ying Song Cheng-lin Zhu Lin-xiu Du Raja Devesh Kumar misra State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang110819LiaoningChina Laboratory for Excellence in Advanced Steel Research Department of MetallurgicalMaterials and Biomedical EngineeringUniversity of Texas at El PasoEl PasoTX79968USA

Hydrogen trapping behavior of v–N microalloyed X80 pipeline steels was studied by means of hydrogen permeation and hydrogen induced cracking(HIC)*** addition,the electrochemical performance of the steels in 3.5 wt.%NaCl solution was *** indicated that the microstructure of experimental steels mainly consisted of acicular ferrite and polygonal ferrite(PF).When the fraction of PF was 9.1%and 30.4%,hydrogen effective diffusion coefficient was 1.624×10^(−6) and 3.121×10^(−6) cm^(2)/s,*** pipeline steels were not susceptible to *** potential hydrogen traps distributed in homogeneous dispersion were conducive to high HIC *** increasing the fraction of PF from 9.1%to 30.4%,the corrosion current density increased from 5.39×10^(−6) to 9.49×10^(−6) A cm^(−2),the corrosion potential decreased from−0.48 to−0.57 v,and the charge transfer resistance decreased from 2301 to 2068Ωcm^(2),*** fraction of PF was disadvantageous for corrosion resistance because of galvanic corrosion.

关键词： Pipeline steel v-N microalloying Hydrogen induced cracking susceptibility Hydrogen permeation Electrochemical corrosion

Joining of AZ91 Mg alloy and Al6063 alloy sheets by friction stir welding

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2018年第1期6卷 71-76页

作者： B.Lakshmana prasad G.Neelaiah M.Gopi Krishna S.v.v.Ramana K.Sai Prakash G.Sarika G.Pradeep Kumar Reddy Ravikumar Dumpala B.ratna Sunil Department of Mechanical Engineering Rajiv Gandhi University of Knowledge Technologies(AP-IIIT)Nuzvid 520201India Department of Mechanical Engineering Vignana Bharathi Institute of TechnologyHyderabad 501301India Department of Mechanical Engineering Visvesvaraya National Institute of TechnologyNagpur 440010India

In the present work,the effect of process parameters on joining of AZ91 Mg alloy and Al6063 aluminum alloy sheets during friction stir welding(FSP)was studied.A successful joint was achieved at 1100 *** rotational speed and 25 mm/min tool travel *** of tool rotational speed and tool travel speed has observed a profound effect on the material flow mechanisms at the nugget *** the microstructural studies,the joint formation was observed as mainly due to mechanical mixing of the *** level of metallurgical continuity at the nugget zone was observed as poor and a sharp interface at the joint was *** microhardness measurements across the weld joint also revealed the lack of establishment of a perfect metallurgical bonding.X-ray diffraction analysis of weld zone showed presence of both magnesium and *** from the preliminary observations,it can be understood that the joining of AZ91 Mg alloy and Al6063 alloy can be achieved by FSP;however,complex issues in material mixing still need further investigations.

关键词： Friction stir welding Dissimilar joints Magnesium Aluminum Nugget zone

Influence of heat treatment on the machinability and corrosion behavior of AZ91 Mg alloy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Magnesium and Alloys 2018年第1期6卷 52-58页

作者： Swetha Chowdary v Ravikumar Dumpala Anand Kumar S Kondaiah vv ratna Sunil B Department of Mechanical Engineering Rajiv Gandhi University of Knowledge Technologies(AP-IIIT)Nuzvid521202India Department of Mechanical Engineering Visvesvaraya National Institute of TechnologyNagpurMaharashtra 440010India Department of Mechanical Engineering Dayananda Sagar UniversityBengaluru560068India Department of Mechanical Engineering Tirumala Engineering CollegeNarasaraopetAndhra Pradesh 522601India

In the present study,AZ91 Mg alloy was heat treated at 410℃ for 6,12 and 24 h to investigate the influence of heat treatment on machinability and corrosion *** effect of soaking time on the amount and distribution of Mg 17 Al 12(β-phase)was analyzed under the optical *** measurements demonstrated the increased hardness with increased heat treatment soaking time,which can be attributed to the solid solution *** influence of super saturatedα-grains on reducing the cutting force(F z)with respect to increased cutting speed was observed as *** corrosion behavior of the heat treated specimens was studied by conducting electrochemical ***,corrosion rate of heat treated samples was observed as increased compared with the base *** the results,it is evident that the machinability of AZ91 Mg alloy can be improved by producing super saturatedα-grains through heat treatment but at the cost of losing corrosion resistance.

关键词： AZ91 Mg alloy Solid solution Turning Corrosion Machinability

Machine learning and deep neural network-based learning in osteoarthritis knee

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Methodology 2023年第5期13卷 419-425页

作者： Harish v K ratna Madhan Jeyaraman Naveen Jeyaraman Arulkumar Nallakumarasamy Shilpa Sharma Manish Khanna Ashim Gupta Department of Orthopaedics Rathimed Speciality HospitalChennai 600040Tamil NaduIndia Department of Orthopaedics ACS Medical College and HospitalDr MGR Educational and Research InstituteChennai 600077Tamil NaduIndia Department of Orthopaedics South Texas Orthopaedic Research InstituteLaredoTX 78045United States Department of Paediatric Surgery All India Institute of Medical SciencesNew Delhi 110029India Department of Orthopaedics Autonomous State Medical CollegeAyodhya 224133Uttar PradeshIndia Department of Regenerative Medicine Regenerative OrthopaedicsNoida 201301Uttar PradeshIndia Department of Regenerative Medicine Future BiologicsLawrencevilleGA 30043United States Department of Regenerative Medicine BioIntegarteLawrencevilleGA 30043United States

Osteoarthritis(OA)of the knee joint is considered the commonest musculoskeletal condition leading to marked disability for patients residing in various regions around the *** of machine learning(ML)in doing research regarding OA has brought about various clinical advances viz,OA being diagnosed at preliminary stages,prediction of chances of development of OA among the population,discovering various phenotypes of OA,calculating the severity in OA structure and also discovering people with slow and fast progression of disease pathology,*** publications are available regarding machine learning methods for the early detection of *** key features are detected by morphology,molecular architecture,and electrical and mechanical *** addition,this particular technique was utilized to assess non-interfering,non-ionizing,and in-vivo techniques using magnetic resonance *** is being utilized in OA,chiefly with the formulation of large cohorts viz,the OA Initiative,a cohort observational study,the Multicentre Osteoarthritis Study,an observational,prospective longitudinal study and the Cohort Hip&Cohort Knee,an observational cohort prospective study of both hip and knee *** ML has various contributions and enhancing applications,it remains an imminent field with high potential,also with its *** more studies are to be carried out to find more about the link between machine learning and knee osteoarthritis,which would help in the improvement of making decisions clinically,and expedite the necessary interventions.

关键词： Osteoarthritis Knee Artificial intelligence Machine learning Deep neural network

Laser optogalvanic investigations of the Neon 6302 A transition

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

原子与分子物理学报 2007年第B8期24卷 102-104页

作者： HAN Xianming L POZDIN v HARIDASS C misra P Department of Physics ＆ Astronomy Butler University Indianapolis IN 46208 CLOE Comell University Ithaca NY 14850 Department of Physical Sciences Belfry School Belfry KY 41514 Department of Physics ＆ Astronomy Howard University Washington D. C20059

The optogalvanic effect of neon, in the presence of CO gas, has been specifically investigated for the 630.2 nm transition. Our theoretical model, based on rate equations, predicts well the observed signals as a sum o... 详细信息

关键词：光电效应信号波形蒙特卡罗法激光