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Comment on “A numerical investigation of the acoustic mode waves in a deviated borehole penetrating a transversely isotropic formation”

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Science China(Physics,Mechanics & Astronomy) 2016年第8期59卷 89-90页

作者： Steve A.Horne Douglas miller CanYun Wang Chevron Energy Technology Corporation London El4 4HA UK Massachusetts Institute of Technology Boston 02139 USA CNPC Logging Company Ltd Beijing 102206 China

In the paper"A numerical investigation of the acoustic mode waves in a deviated borehole penetrating a transversely isotropic formation"by Liu et al.[1]numerical experiments are reported for a dipole sonic logging scenario with a deviated borehole penetrating a VTI anisotropic *** such a situation it is important to clearly define the meaning of group and phase velocities as this has led to much confusion in the literature as discussed by miller,Horne and Walsh[2].

关键词： penetrating Comment on isotropic borehole logging sonic confusion dipole deviation clearly

Design of synthetic materials for intracellular delivery of RNAs： From siRNA-mediated gene silencing to CRISPR/Cas gene editing

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Nano Research 2018年第10期11卷 5310-5337页

作者： Jason B. miller Daniel J. Siegwart Simmons Comprehensive Cancer Center University of Texas Southwestern Medical Center Dallas TX 75390 USA Department of Biochemistry University of Texas Southwestern Medical Center Dallas TX 75390 USA

Ribonucleic acids （RNAs） possess great therapeutic potential and can be used to treat a variety of diseases. The unique biophysical properties of RNAs, such as high molecular weight, negative charge, hydrophilicity, low stability, and potential immunogenicity, require chemical modification and development of carriers to enable intracellular delivery of RNAs for clinical use. A variety of nanornaterials have been developed for the effective in vivo delivery of short/ small RNAs, messenger RNAs, and RNAs required for gene editing technologies including clustered regularly interspaced palindromic repeat （CRISPR）/Cas. This review outlines the challenges of delivering RNA therapeutics, explores the chemical synthesis of RNA modifications and carriers, and describes the efforts to design nanomaterials that can be used for a variety of clinical indications.

关键词： nucleic acid therapeutics nanoparticles synthetic nanomaterials RNA interference (RNAi) messenger RNA (mRNA) clustered regularly inter-spaced palindromic repeat(CRISPR)/Cas

Evaluation of the 20 L dust explosibility testing chamber and comparison to a modified 38 L vessel for underground coal

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International Journal of Mining Science and Technology 2018年第6期28卷 885-890页

作者： Robert Eades Kyle Perry Catherine Johnson Jacob miller Department of Mining and Nuclear Engineering Missouri University of Science and Technology

The phenomenon of combustible dust explosions is present within many industries. Tests for explosibility of dust clouds per ASTM E1226 use a 20 L explosive chamber that places the combustible dust directly below the dispersion nozzle which generates a thorough mixture for testing purposes. However, in the underground coal mining industry, there are a number of geologic, mining, and regulatory factors that change the deposition scheme of combustible coal dust. This causes the atmosphere of a coal mine to have a variable rock dust-coal dust mixture at the time of ignition. To investigate the impact of this variable atmosphere, a series of lean explosibility tests were conducted on a sample of Pittsburgh Pulverized coal dust. These explosibility tests were conducted in a 38 L chamber with a 5 kJ Sobbe igniter. The 38 L chamber generates a variable air-dust mixture prior to ignition. The test results indicate that the 38 L chamber experiences reduced explosive pressures, and lower explosibility index values when compared to the 20 L chamber.

关键词： Dust explosion Coal mining Coal dust Explosibility testing

伊伐布雷定引起的心动过缓可减轻与压力相关的焦虑

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中华高血压杂志(中英文) 2024年第4期32卷 400-400页

作者： Woodman R Student J miller C Lockette W 刘青练桂丽

背景：心率较高且焦虑的高血压患者心血管疾病发病率和死亡率较高。尽管高血压、心率和焦虑之间存在相关性，但人们很少关注高血压药物治疗对心血管疾病行为结果的影响。伊伐布雷定是一种超极化激活的环核苷酸门控通道(hyperpolarizatio...

背景：心率较高且焦虑的高血压患者心血管疾病发病率和死亡率较高。尽管高血压、心率和焦虑之间存在相关性，但人们很少关注高血压药物治疗对心血管疾病行为结果的影响。伊伐布雷定是一种超极化激活的环核苷酸门控通道(hyperpolarization-activated, cyclic nucleotide-gated funny channels, HCN)抑制剂，已在临床上用于降低心率，并已被证明可以改善心绞痛和心力衰竭患者的生活质量。

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A Scalable Testing Framework for Location-Based Services

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Journal of Computer Science & Technology 2009年第2期24卷 386-404页

作者： Jiang Yu Andrew Tappenden James miller Michael Smith University of Alberta Edmonton T6G 2E1 Canada University of Calgary Calgary T2N 1N4 Canada

A novel testing framework for location based services is introduced. In particular, the paper showcases a novel architecture for such a framework. The implementation of the framework illustrates both the functionality and the feasibility of the framework proposed and the utility of the architecture. The new framework is evaluated through comparison to several other methodologies currently available for the testing of location-based applications. A case study is presented in which the testing framework was applied to a typical mobile service tracking system. It is concluded that the proposed testing framework achieves the best coverage of the entire location based service testing problem of the currently available methodologies; being equipped to test the widest array of application attributes and allowing for the automation of testing activities.

关键词： location based applications location-based services M-commerce software testing

Anion structural effects on interaction of rare earth element ions with Dowex 50W X8 cation exchange resin

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Journal of Rare Earths 2018年第8期36卷 879-890页

作者： Duane D.miller Ranjani Siriwardane Dustin Mcintyre U.S. Department of Energy National Energy Technology Laboratory AECOM

The effect of the anion in the original rare earth element（REE） solution on the reversible ion exchange of Ce nitrate and Ce sulfate with the Dowex 50 W X8 was investigated using attenuated total reflection infrared（ATR-IR） spectroscopy, continuous flow reactor studies coupled with inductively coupled plasma mass spectroscopy（ICP-MS）, and density functional theory（DFT）. The simulated IR spectrum at the DFT B3 LYP/6-31 G（d） level was compared to the experimental results to characterize the IR spectrum, molecular interactions, and bonding of the ion exchanged species. The continuous liquid flow reactor studies show a capacity of 0.72 mmol/g sorbent for the Ce nitrateand 0.96 mmol/g sorbent for the Ce sulfate with the Dowex 50 W X8. The flow reactor studies reveal the type of solute anion（SO_4^（（2-）） or NO_3^（（-））） associated with the REE during cation exchange significantly affects the sorption capacity of the Dowex 50 W X8 ion exchange resin. The calculated REE binding energy（BE） and the DFT optimized structures suggest that the differences in sorption capacity is the result of the formation of different types of partially ionexchanged Ce_2^（（3＋））2 SO_4^（（2-）） and Ce^（（3＋）） 3 NO_3^（（-））. These results suggest that the solute anion affects the equilibrium constants of the Dowex resin by the formation of a charged layer capable of retaining the counterion. Modifying the sulfonic acid site（H＋） in the Dowex 50 W X8 with the NH_4~＋ counterion does not affect the sorption capacity and retention times of the Ce nitrate and Ce sulfate species. These results suggest that the counterions and co-ions having a finite size, may limit access to the Dowex sulfonate active site where the type of REE cation as a nitrate or sulfate in solution may significantly modify the sorption capacity of the ion exchange resin. Similar results are obtained during sorption with nitrates and sulfates of Sm and Yb.

关键词： Ion exchange Dowex Anion effects Rare earth metal sorption

Closed-loop subspace identification algorithm based on correlation function estimates

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Science China(Information Sciences) 2015年第3期58卷 173-182页

作者： WANG Jia miller Daniel WANG HongWei GU Hong Department of Biotechnology Dalian Medical University School of Control Science and Engineering Dalian University of Technology Department of Mechanical Engineering University of California San Diego

A novel subspace identification method based on correlation function which estimates a state-space system dynamics of unknown plant operating in closed-loop experimental condition is proposed in this *** is shown that the cross-correlation function of the output and external input signals are equal to the crosscorrelation function of the input and external signals filtered through the system dynamics since noise signal has no correlation with the external *** proposed algorithm is developed to obtain unbiased estimates of system matrices based on time-shifted invariance of the correlation function *** the algorithm is compared to other popular subspace methods in the simulation study and the results show the effectiveness of our method in the presence of colored noise and low signal-to-noise ratios.

关键词： subspace identification method correlation function estimates closed-loop system asymptotic properties the system dynamics

Rate analysis of sorption of Ce^3＋,Sm^3＋,and Yb^3＋ions from aqueous solution using Dowex 50W-X8 as a sorbent in a continuous flow reactor

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Journal of Rare Earths 2018年第6期36卷 648-655页

作者： Esmail Monazam Ranjani Siriwardane Duane miller Dustin Mclntyre REM Engineering Services PLLC3537 Collins Ferry Rd.MorgantownWV 26505USA National Energy Technology Laboratory U.S.Department of Energy3610 Collins Ferry Rd.MorgantownWV26507-0880USA AECOM 3610 Collins Ferry Rd.E O.Box 880MorgantownWV 26507-0880USA

Kinetic analysis of removal of three rare earth elements metals, Ce, Sm, and Ybions from aqueous solutions in a continuous flow fixed bed reactor using Dowex 50 W-X8 ion-exchange resin was conducted. The performance of the fixed bed sorption was evaluated using the concept of the sorption breakthrough process. Parameters characteristic of a fixed bed sorption such as breakthrough times,saturation times, critical reactor lengths, and lengths of mass transfer zone were inferred from the metal ion concentration breakthrough curves. The sorption capacity of Dowex 50 W-X8 ion-exchange resin for Ce3+, Sm3+, and Yb3+ are 191, 252, and 294 mg/g, respectively. The sorption kinetics were evaluated using a zero-order, first-order and second-order reaction models. The kinetics of the sorption process follows a zero-order model which has not been reported before. The rate constants of sorption using the zero-order kinetic model are obtained. Two different analysis were conducted to identify whether the diffusion is intraparticle or film diffusion. Both analysis confirms that the film diffusion is the controlling mechanism in reactor bed.

关键词： Rare earth metal ion removal Sorption of rare earths Dowex 50W-X8 for rare earth ion-exchange

Of Palaces and Pagodas： Palatial Symbolism in the Buddhist Architecture of Early Medieval China

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Frontiers of History in China 2015年第2期10卷 222-263页

作者： Tracy miller Department of History of Art Vanderbilt University Nashville TN 37203 USA

This paper is an inquiry into possible motivations for representing timber-flame architecture in the Buddhist context. By comparing the architectural language of early Buddhist narrative panels and cave temples rendered in stone, I suggest that architectural representation was employed in both masonry and timber to create symbolically charged worship spaces. The replication and multiplication of palace forms on cave walls, in ＂pagodas＂（futu浮圖,fotu 佛圖, or ta 塔）, and as the crowning element of flee-standing pillars reflect a common desire to express and harness divine power, a desire that resulted in a wide variety of mountainous monuments in China. Finally, I provide evidence to suggest that the towering Buddhist monuments of early medieval China are linked morphologically and symbolically to the towering temples of South Asia through the use of both palace forms and sacred man. d. alas as a means to express the divine power and expansive presence of the Buddha.

关键词： Pagoda ta mandala Sumeru Yicihui pillar Yongningsi Songyuesi