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Microsurgical management of radicular cyst using guided tissue regeneration technique:A case report

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World Journal of Clinical Cases 2024年第7期12卷 1346-1355页

作者： Juan Carlos Gómez mireles Eugenia Karina Martínez Carrillo Katia Alcalá Barbosa Evangelina Gutiérrez Cortés Javier gonzález Ramos Luis Antonio gonzález Gómez Rubén Alberto Bayardo gonzález Sarah Monserrat Lomelí Martínez Periodontics Specialty Department of Integral Dentistry ClinicsCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340Mexico Endodontics Specialty Department of Integral Dentistry ClinicsCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340Mexico Endodontics Specialty Department of ClinicsCentro Universitario de Los AltosUniversidad de GuadalajaraTepatitlán de Morelos 47620Mexico Specialty in oral Pathology Surgical-Stomatological DepartmentAutonomous University of GuadalajaraZapopan 45129Mexico Independent Researcher Guadalajara 44340Mexico Department of Integral Dentistry Clinics Centro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340Mexico Department of Medical and Life Sciences Centro Universitario de la CiénegaUniversidad de GuadalajaraOcotlán 47810Mexico Master of Public Health Department of Well-being and Sustainable DevelopmentCentro Universitario del NorteUniversidad de GuadalajaraColotlán 46200Mexico

BACKGRoUND Radicular cyst is a lesion of odontogenic origin that arises from epithelial remains due to periapical periodontitis caused by inflammatory reactions generated at the apex of affected teeth with infected or necrotic *** therapeutic mana gement of radicular cysts is *** is only one case report of enucleation of a radicular cyst managed with microsurgery and apicoectomy,but without the use of the guided tissue regeneration(GTR)technique in the same surgical *** present clinical case describes the management of a radicular cyst with microsurgical approach,performance of an apicoectomy of the tooth associated with the entity,application of GTR technique,use of a resorbable membrane of type I bovine collagen,and bovine *** SUMMARY A 68-year-old patient presented with a radicular cyst from an upper lateral *** microsurgical management used was aimed at enucleating the chemical membrane,performing apicoectomy of the tooth along with careful and precise retrograde filling,and implementing GTR technique using a resorbable collagen membrane and bovine *** diagnosis of radicular cyst was confirmed using histopathological *** patient underwent follow-up evaluations at 10 and 30 d *** 4 months postoperative evaluation,she remained asymptomatic,and radiographs showed significant periapical healing with adequate bone *** These results suggest that microsurgical management using the GTR technique with collagen membrane and xenograft,contributes to bone regeneration.

关键词： odontogenic cysts Apical periodontal cyst Dental root end cyst Case report

Vault RNAs(vtRNAs):Rediscovered non-coding RNAs with diverse physiological and pathological activities

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Genes & Diseases 2024年第2期11卷 772-787页

作者： Mahsa Aghajani mir Deputy of Research and Technology Health Research InstituteBabol University of Medical SciencesBabol 47176-4774Iran

The physicochemical characteristics of RNA admit non-coding RNAs to perform a different range of biological acts through various mechanisms and are involved in regulating a diversity of fundamental ***,some reports of pathological conditions have proved abnormal expression of many non-coding RNAs guides the *** RNAs are a class of non-coding RNAs containing stem regions or loops with well-conserved sequence patterns that play a fundamental role in the function of vault particles through RNA-ligand,RNA–RNA,or RNA-protein *** together,vault RNAs have been proposed to be involved in a variety of functions such as cell proliferation,nucleocytoplasmic transport,intracellular detoxification processes,multidrug resistance,apoptosis,and autophagy,and serve as microRNA precursors and signaling *** decades of investigations devoted,the biological function of the vault particle or the vault RNAs is not yet completely *** this review,the current scientific assertions of the vital vault RNAs functions were discussed.

关键词： ncRNA Vault complex Vault RNA vtRNA viral infection tumorigenesis

From the backyard to collective gardens in the “blue-courtyard”: Reversing the process of upgrading historic timber-framed courtyard buildings in Madrid

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Frontiers of Architectural Research 2024年第2期13卷 265-283页

作者： Esperanza gonzalez-Redondo Department of Architecture University of AlcalaMadridSpain

This paper presents an analytical framework for evaluating the impact of the two main processes identified in Madrid timber-framed courtyard buildings reinforcing the courtyard's crucial role in architectural heritage sustainability:their development caused dwellings to darken(1737–1950),and the existing challenge is to open new patios according to the listed buildings'protection *** findings in archival research and existing building assessments led to completed data collection and *** exploring construction expansion,from the house towards the collective prototype around a gradually reduced patio and dwelling darkening(1737–1786),buildings resulted in open,semiopen,underlighted and closed *** area on-site assessment uncovered the transition from the older low-rise type(1–3)floors to the modern closed model of up to(4–6)*** enlargements,consequently reducing original green areas and courtyards,call for reversing that process or formulating a new *** debates the partial demolition of listed buildings in upgrades and its agreement with the needed“blue courtyard”strategy(PGoUM),resulting from joining new rear individual patios to create a communal building block *** uncovered“in-between”type(1864),which integrates two open-air collective spaces,an inner courtyard and a back garden,appears challenging to explore.

关键词： Courtyard Sustainabledesign Architectural heritage Archives Timber-framed construction Social housing

Glucagon-like peptide 1 receptor activation:anti-inflammatory effects in the brain

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Neural Regeneration Research 2024年第8期19卷 1671-1677页

作者： Yolanda Diz-Chaves Zainab Maastor Carlos Spuch José Antonio Lamas Lucas C.gonzález-Matías Federico Mallo Biomedical Research Centre(CINBIo) Laboratory of EndocrinologyUniversity of VigoGalicia Sur Health Research InstituteVigoSpain Translational Neuroscience Research Group Galicia Sur Health Research InstituteCIBERSAMHospitalÁlvaro CunqueiroSala InvestigaciónEstrada Clara CampoamorVigoSpain Biomedical Research Centre(CINBIo) Laboratory of NeuroscienceUniversity of VigoGalicia Sur Health Research InstituteVigoSpain

The glucagon-like peptide 1 is a pleiotropic hormone that has potent insulinotropic effects and is key in treating metabolic diseases such as diabetes and ***-like peptide 1 exerts its effects by activating a membrane receptor identified in many tissues,including diffe rent brain ***-like peptide 1 activates several signaling pathways related to neuroprotection,like the support of cell growth/survival,enhancement promotion of synapse formation,autophagy,and inhibition of the secretion of proinflammatory cytokines,microglial activation,and apoptosis during neural *** glial cells,including astrocytes and microglia,maintain metabolic homeostasis and defe nse against pathogens in the central nervous *** brain insult,microglia are the first cells to respond,followed by reactive *** activated cells produce proinflammato ry mediators like cytokines or chemokines to react to the ***,under these circumstances,mic roglia can become chro nically inflammatory by losing their homeostatic molecular signature and,consequently,their functions during many *** processes promote the development of neurological disorders and influence their pathological evolution:like the formation of protein aggregates,the accumulation of abnormally modified cellular constituents,the formation and release by injured neurons or synapses of molecules that can dampen neural function,and,of critical impo rtance,the dysregulation of inflammato ry control *** glucagonlike peptide 1 receptor agonist emerges as a critical tool in treating brain-related inflammatory pathologies,restoring brain cell homeostasis under inflammatory conditions,modulating mic roglia activity,and decreasing the inflammato ry *** review summarizes recent advances linked to the anti-inflammato ry prope rties of glucagon-like peptide 1 receptor activation in the brain related to multiple sclerosis,Alzheimer’s disease,Parkins

关键词： astrocytes brain glucagon-like peptide 1 receptor inflammation microglia

Chi-square automatic interaction detection(CHAID)analysis of the use of safety goggles and face masks as personal protective equipment(PPE)to protect against occupational biohazards

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Journal of Biosafety and Biosecurity

Journal of Biosafety and Biosecurity 2024年第2期6卷 125-133页

作者： Raúl Aguilar-Elena Juán JoséAgún-gonzález Universidad Internacional de Valencia ValenciaSpain

Background:This study represents the first Spanish investigation to rigorously evaluate compliance with the use of safety goggles and face masks as essential personal protective equipment(PPE)in companies with workplaces involving exposure to biological ***:This study aimed to examine the degree of use of face masks and safety goggles as personal protective equipment(PPE),the factors that influence their use,and the profile of workers exposed to occupational biological agents in Spanish companies in the health sector,farming sector,meat industry,waste treatment plants,food industry,and veterinary ***:We conducted a cross-sectional descriptive study involving 590 Spanish workers from 51 *** developed a 34-item questionnaire to assess workers’perception of risk related to exposure to biological agents in their *** the questions,three were designed to measure the degree of use of key protective equipment in sectors with biological agent exposure:protective gloves,safety goggles or face *** only analyzed safety goggles and face *** performed various statistical analyses,including Cronbach’s alpha,frequency of endorsement,content validity ratio using Lawshe’s method,varimax rotation,the Kaiser-Meyer-olkin test,and Bartlett’s sphericity test,to assess the internal consistency and reliability of the ***,we employed a chi-square automatic interaction detection(CHAID)segmentation analysis,using workers’responses regarding their attitudes toward safety goggles and face mask usage as PPE for protection against biological risks,with demographic variables as independent ***:In the current study,CHAID analysis revealed that workers exposed to group 2 biological agents used more safety goggles and face shields compared with workers exposed to other groups of biological ***,workers in laboratories and the food industry used face masks more than workers of other ***

关键词： PPE Safety googles and breath mask CHAID Biological Agents occupational Biosafety

Un clavado por la amistad

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今日中国（西文版） 2024年第2期 44-45页

作者： CARMEN gonzÁlez 不详

Un puente estético con México

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今日中国（西文版） 2024年第3期 45-46页

作者： CARMEN gonzÁlez 不详

The potential of starch-chitosan blends with poloxamer for the preparation of microparticles by spray-drying

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Particuology 2024年第6期89卷 1-10页

作者： Juan Enrique Barranco-García Carolina Caicedo Enrique Javier Jiménez-Regalado Carlos Espinoza-gonzález Graciela Morales Rocio Yaneli Aguirre-Loredo Abril Fonseca-García Tecnológico Nacional de México/Instituto Tecnológico de oaxaca Departamento de Química y BioquímicaAvenida Ing.Víctor Bravo Ahuja No.125Esquina Calzada Tecnológico68030OaxacaMexico Faculty of Engineering Unidad Central del Valle del Cauca(UCEVA)Carrera 17a 48-144763022TuluáColombia Centro de Investigación en Química Aplicada(CIQA) Blvd.Enrique Reyna Hermosillo 14025294SaltilloCoahuilaMexico Investigadoras por México CoNAHCYT-CIQA Av.Insurgentes Sur 1562Col.Crédito Constructor03940Alcaldía Benito JuárezCDMXMexico

Using biopolymers as wall materials in spray drying poses challenges,particularly in attaining flowability and thermal stability among their physicochemical *** paper addresses these challenges by preparing microparticles using a blend of starch–chitosan and a poloxamer,commercially named Pluronic®*** aimed to elucidate the effects of varying poloxamer concentrations on the resulting particles through the spray drying *** with a poloxamer concentration of 3%(w/v)demonstrated a notably higher yield,especially when compared to those with 0%and 1%*** with 3%and 5%(w/v)poloxamer displayed a narrower particle size distribution,with the 3%blend showing a superior yield attributed to arrangements of blend components that improve flowability.X-ray diffraction analysis showcased the characteristic peaks of A-type starch form,with shifts suggesting enhanced interactions between *** with increased poloxamer content showed elevated thermal degradation temperatures,with the 3%blend registering a significant rise,opening avenues for encapsulating heat-sensitive *** study primarily focuses on the preparation and basic characterization of *** underscores the potential of blends with optimal poloxamer concentrations in microencapsulation,emphasizing further research to harness their capabilities thoroughly.

关键词： Biopolymer Starch Chitosan Pluronic®F127 Microparticles Spray drying

Highly divergent sympatric lineages of Leptotila verreauxi(Aves:Columbidae)suggest a secondary contact area in the Isthmus of Tehuantepec,Mexico

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Avian Research 2024年第1期15卷 12-21页

作者： orlando J.Espinosa-Chávez Adolfo G.Navarro-Sigüenza Hernando Rodríguez-Correa Luis A.Sánchez-gonzález Museo de Zoología“Alfonso L.Herrera” Depto.de Biología EvolutivaFacultad de CienciasUniversidad Nacional Autonoma de MexicoApdo.Postal 70-399CP 04510Ciudad de MexicoMexico Posgrado en Ciencias Biologicas Unidad de PosgradoEdificio D1◦PisoCircuito de PosgradosCiudad UniversitariaUniversidad Nacional Autonoma de MexicoCoyoacanCP 04510CDMXMexico Escuela Nacional de Estudios Superiores Unidad Morelia Universidad Nacional Autonoma de Mexico.Antigua Carretera a Patzcuaro No.8701 Col.Ex Hacienda de San Jose de la HuertaC.P.58190MoreliaMichoacanMexico

Due to a complex geological and biotic history,the Isthmus of Tehuantepec(IT),has been long recognized as a driver for the evolutionary divergence of numerous lowland and highland *** distributed in the lowlands of the american continent,the White-Tipped Dove(Leptotila verreauxi)is a polytypic species with 13 recognized *** of these have been recorded in Mexico,and the distribution of three abuts at the IT,suggesting a contact *** estimate phylogenetic patterns,divergence times and genetic differentiation,we examined two mt DNA(ND2 and CoI)and one n DNA(β-fibint 7)*** also used correlative ecological niche models(ENM)to assess whether ecological differences across the IT may have acted as a biogeographical *** estimated paleodistributions during the Middle Holocene,Last Glacial Maximum and Last Interglacial,to evaluate the influence of climate changes on the distribution and demographic *** results showed genetically distinct lineages that diverged approximately 2.5 million years *** and ecological factors may have played a dual role in promoting differentiation,but also in the formation of a secondary contact zone in the southern *** ecological niche comparisons indicated that the ecological niche of sympatric lineages at the IT are not identical,suggesting niches divergence;in addition,environmental niche models across the region indicated no abrupt biogeographic barriers,but the presence of regions with low *** results suggest that genetic differentiation originated by a vicariant event probably related to environmental factors,favored the evolution of different ecological ***,the absence of a biogeographic barrier but the presence of less suitable areas in the contact regions,suggest that secondary contact zones may be also maintained by climatic factors for the eastern group,but also by biotic interactions for the western group.

关键词： Biogeographical boundary Humid and dry forests Isthmus of Tehuantepec Phylogeography Secondary contact