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Optimal postoperative surveillance strategies for stage III colorectal cancer

World Journal of Gastrointestinal Surgery 2021年第9期13卷 1012-1024页

作者： Min Young Park In Ja Park Hyo Seon Ryu Jay Jung minsung kim Seok-Byung Lim Chang Sik Yu Jin Cheon kim Colon and Rectal Surgery Asan Medical CenterSeoul 05505South Korea Colon and Rectal Surgery Asan Medical Center and University of Ulsan College of MedicineSeoul 05505South Korea

BACKGROUND Optimal surveillance strategies for stage III colorectal cancer(CRC)are lacking,and intensive surveillance has not conferred a significant survival *** To examine the association between surveillance intensity and recurrence and survival rates in patients with stage III *** Data from patients with pathologic stage III CRC who underwent radical surgery between January 2005 and December 2012 at Asan Medical Center,Seoul,Korea were retrospectively *** consisted of abdominopelvic computed tomography(CT)every 6 mo and chest CT annually during the 5 year follow-up period,resulting in an average of three imaging studies per *** who underwent more than the average number of imaging studies annually were categorized as high intensity(HI),and those with less than the average were categorized as low intensity(LI).RESULTS Among 1888 patients,864(45.8%)were in HI ***,sex,and location were not different between *** group had more advanced T and N stage(P=0.002,0.010,each).Perineural invasion(PNI)was more identified in the HI group(21.4%vs 30.3%,P<0.001).The mean overall survival(OS)and recurrence-free interval(RFI)was longer in the LI group(P<0.001,each).Multivariate analysis indicated that surveillance intensity[odds ratio(OR)=1.999;95%confidence interval(CI):1.680–2.377;P<0.001],pathologic T stage(OR=1.596;95%CI:1.197–2.127;P=0.001),PNI(OR=1.431;95%CI:1.192–1.719;P<0.001),and circumferential resection margin(OR=1.565;95%CI:1.083–2.262;P=0.017)in rectal cancer were significantly associated with *** mean post-recurrence survival(PRS)was longer in patients who received curative resection(P<0.001).Curative resection rate of recurrence was not different between HI(29.3%)and LI(23.8%)groups(P=0.160).PRS did not differ according to surveillance intensity(P=0.802).CONCLUSION Frequent surveillance with CT scan do not improve OS in stage III CRC *** need to evaluate role of other surveillance method rather tha

关键词： Colorectal cancer Surveillance intensity Survival Recurrence

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A Highly Luminous LiCaPO<sub>4</sub>:Eu<sup>2+</sup>Phosphor Synthesized by a Solution Method Employing a Water-Soluble Phosphate Ester

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Optics and Photonics Journal 2013年第6期3卷 13-18页

作者： minsung kim Makoto Kobayashi Hideki Kato Masato Kakihana Institute of Multidisciplinary Research for Advanced Materials Tohoku University Sendai Japan

A LiCaPO4:Eu2+ phosphor with high photoluminescence was synthesized using a polymerizable complex (PC) method employing a water-soluble polyethylene glycol-conjugated phosphate ester (PEG-P). PEG-P could be obtained from a reaction among polyethylene glycol 300, phosphorus pentoxide, and pyrophosphoric acid. The PEG-P prepared was stable in an aqueous condition. A transparent solution and gel were obtained when the PEG-P was used as a source of P during the PC method, whereas the use of H3PO4 caused an undesirable precipitate. The LiCaPO4:Eu2+ obtained via the PC method employing the PEG-P showed higher emission intensity than those synthesized by a solid state reaction method and the PC method employing H3PO4. The high luminescence properties of the sample synthesized using the PEG-P may be attributed to high homogeneity of constituents in the sample.

关键词： Solution Method Stable Phosphate Ester Homogeneity LiCaPO4:Eu2+

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Blood transcriptomic markers associated with immune abnormalities and sleep quality

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Genes & Diseases 2024年第6期11卷 111-114页

作者： Sang-Min Park Hyo-Jeong Ban minsung Lee Soo Yeon kim Siwoo Lee Hee-Jeong Jin College of Pharmacy Chungnam National UniversityDaejeon34134Republic of Korea Korean Medicine(KM)Data Division Korea Institute of Oriental MedicineDaejeon 34054Republicof Korea

The prevalence of sleep disorders is increasing worldwide,prompting greater efforts to understand the biological mechanisms underlying *** the growing interest in this area,a continuous transcriptome analysis for studying sleep quality is still *** study performed a regression analysis of the Pittsburgh sleep quality index(PsQ)from the blood transcriptome to identify marker genes associated with sleep quality.

关键词： sleep Blood prevalence

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Spacesuit Textiles from Extreme Fabric Materials: Aromatic Amide Polymer and Boron Nitride Nanotube Composite Fiber for Neutron Shielding and Thermal Management

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ADVANCED FIBER MATERIALS 2024年第5期6卷 1509-1520页

作者： Ryu, Ki-Hyun Kang, minsung kim, Jungwon You, Nam-Ho Jang, Se Gyu Jeong, Kwang-Un Ahn, Seokhoon kim, Dae-Yoon Korea Inst Sci & Technol Funct Composite Mat Res Ctr Wonju 55324 South Korea Korea Inst Sci & Technol Carbon Composite Mat Res Ctr Wonju 55324 South Korea Jeonbuk Natl Univ Dept Polymer Nano Sci & Technol Jeonju 54896 South Korea Jeonbuk Natl Univ Dept Nano Convergence Engn Jeonju 54896 South Korea

Space exploration provides unparalleled opportunities for unraveling the mysteries of our origins and exploring planetary systems beyond Earth. Long-distance space missions require successful protection against significant radiation exposure, necessitating the development of effective radiation shielding materials. This study developed aromatic amide polymer (AAP) and boron nitride nanotube (BNNT) composite fibers using lyotropic liquid crystal (LLC) and industrially viable wet-spinning processes. The uniaxially oriented 1D composite fibers provide the necessary continuity and pliability to fabricate 2D macroscopic textiles with low density (1.80 g cm-3), mechanical modulus (18.16 GPa), and heat stability (up to 479 degrees C), while exhibiting the improved thermal neutron absorption cross-section with thermal neutron-shielding performance (0.73 mm-1). These composite textiles also show high thermal conductivity (7.88 W m-1 K-1) due to their densely packed and uniaxially oriented structures. These enhanced characteristics render the fibers a highly promising material for space applications, offering robust protection for both astronauts and electronics against the dual threats of radiation and heat.

关键词： Lyotropic liquid crystal Robust composite material Space radiation shielding Thermal conductive pathway

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