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Novel Architecture of Security Orchestration, Automation and Response in Internet of Blended Environment

Computers, Materials & Continua 2022年第10期73卷 199-223页

作者： minkyung lee Julian Jang-Jaccard Jin Kwak ISAA Lab Department of Cyber SecurityAjou UniversitySuwon16499Korea Department of Computer Science and Information Technology Massey UniversityAuckland0745New Zealand Department of Cyber Security Ajou UniversitySuwon16499Korea

New technologies that take advantage of the emergence of massive Internet of Things(IoT)and a hyper-connected network environment have rapidly increased in recent years.These technologies are used in diverse environments,such as smart factories,digital healthcare,and smart grids,with increased security concerns.We intend to operate Security Orchestration,Automation and Response(SOAR)in various environments through new concept definitions as the need to detect and respond automatically to rapidly increasing security incidents without the intervention of security personnel has emerged.To facilitate the understanding of the security concern involved in this newly emerging area,we offer the definition of Internet of Blended Environment(IoBE)where various convergence environments are interconnected and the data analyzed in automation.We define Blended Threat(BT)as a security threat that exploits security vulnerabilities through various attack surfaces in the IoBE.We propose a novel SOAR-CUBE architecture to respond to security incidents with minimal human intervention by automating the BT response process.The Security Orchestration,Automation,and Response(SOAR)part of our architecture is used to link heterogeneous security technologies and the threat intelligence function that collects threat data and performs a correlation analysis of the data.SOAR is operated under Collaborative Units of Blended Environment(CUBE)which facilitates dynamic exchanges of data according to the environment applied to the IoBE by distributing and deploying security technologies for each BT type and dynamically combining them according to the cyber kill chain stage to minimize the damage and respond efficiently to BT.

关键词： Blended threat(BT) collaborative units for blended environment(CUBE) internet of blended environment(IoBE) security orchestration,automation and response(SOAR)

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Detection Technique of Software-Induced Rowhammer Attacks

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Computers, Materials & Continua 2021年第4期67卷 349-367页

作者： minkyung lee Jin Kwak ISAA Lab. Department of Computer EngineeringAjou UniversitySuwon16499Korea Department of Cyber Security Ajou UniversitySuwon16499Korea

Side-channel attacks have recently progressed into software-induced attacks.In particular,a rowhammer attack,which exploits the characteristics of dynamic random access memory(DRAM),can quickly and continuously access the cells as the cell density of DRAM increases,thereby generating a disturbance error affecting the neighboring cells,resulting in bit flips.Although a rowhammer attack is a highly sophisticated attack in which disturbance errors are deliberately generated into data bits,it has been reported that it can be exploited on various platforms such as mobile devices,web browsers,and virtual machines.Furthermore,there have been studies on bypassing the defense measures of DRAM manufacturers and the like to respond to rowhammer attacks.A rowhammer attack can control user access and compromise the integrity of sensitive data with attacks such as a privilege escalation and an alteration of the encryption keys.In an attempt to mitigate a rowhammer attack,various hardware-and software-based mitigation techniques are being studied,but there are limitations in that the research methods do not detect the rowhammer attack in advance,causing overhead or degradation of the system performance.Therefore,in this study,a rowhammer attack detection technique is proposed by extracting common features of rowhammer attack files through a static analysis of rowhammer attack codes.

关键词： Rowhammer attack static analysis detecting technique side-channel attack bit flip

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Melatonin combined with exercise cannot alleviate cerebral injury in a rat model of focal cerebral ischemia/reperfusion injury

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Neural Regeneration Research 2012年第13期7卷 993-999页

作者： Seunghoon lee Jinhee Shin minkyung lee Yunkyung Hong Sang-Kil lee Youngjeon lee Tserentogtokh Lkhagvasuren Dong-Wook Kim Young-Ae Yang Kyu-Tae Chang Yonggeun Hong Department of Rehabilitation Science in Interdisciplinary Ph.D.Program Inje UniversityGimhae 621-749Republic of Korea Cardiovascular & Metabolic Disease Center College of Biomedical Science & EngineeringGimhae 621-749Republic of Korea Department of Smart Foods & Drugs School of Food & Life SciencesInje UniversityGimhae 621-749Republic of Korea Department of Pharmaceutical Engineering College of EngineeringInje UniversityGimhae 621-749Republic of Korea National Primate Research Center Korea Research Institute of BiotechnologyOchang 363-883Republic of Korea

Previous studies have demonstrated that melatonin combined with exercise can alleviate secondary damage after spinal cord injury in rats. Therefore, it is hypothesized that melatonin combined with exercise can also alleviate ischemic brain damage. In this study, adult rats were subjected to right middle cerebral artery occlusion after receiving 10 mg/kg melatonin or vehicle subcutaneously twice daily for 14 days. Forced exercise using an animal treadmill was performed at 20 m/min for 30 minutes per day for 6 days prior to middle cerebral artery occlusion. After middle cerebral artery occlusion, each rat received melatonin combined with exercise, melatonin or exercise alone equally for 7 days until sacrifice. Interestingly, rats receiving melatonin combined with exercise exhibited more severe neurological deficits than those receiving melatonin or exercise alone. Hypoxia-inducible factor la mRNA in the brain tissue was upregulated in rats receiving melatonin combined with exercise. Similarly, microtubule associated protein-2 mRNA expression was significantly upregulated in rats receiving melatonin alone. Chondroitin sulfate proteoglycan 4 （NG2） mRNA expression was significantly decreased in rats receiving melatonin combined with exercise as well as in rats receiving exercise alone. Furthermore, neural cell loss in the primary motor cortex was significantly reduced in rats receiving melatonin or exercise alone, but the change was not observed in rats receiving melatonin combined with exercise. These findings suggest that excessive intervention with melatonin, exercise or their combination may lead to negative effects on ischemia/reperfusion-induced brain damage.

关键词： wfocal cerebral ischemiaJreperfusion melatonin exercise neurological function brain tissue loss microtubule associated protein-2 chondroitin sulfate proteoglycan 4 NG2 hypoxia-inducible factor1 alpha neural regeneration

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Middle cerebral artery occlusion methods in rat versus mouse model of transient focal cerebral ischemic stroke

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Neural Regeneration Research 2014年第7期9卷 757-758页

作者： Seunghoon lee minkyung lee Yunkyung Hong Jinyoung Won Youngjeon lee Sung-Goo Kang Kyu-Tae Chang Yonggeun Hong Department of Rehabilitation Science Graduate School of Inje University Ubiquitous Healthcare & Anti-aging Research Center Inje University Cardiovascular & Metabolic Disease Center Inje University National Primate Research Center (NPRC) Korea Research Institute of Bioscience and Biotechnology (KRIBB) Ochang School of Biological Sciences College of Biomedical Science & Engineering Inje University Department of Physical Therapy Graduate School of Inje University

Experimental stroke research commonly employs focal cerebral ischemic rat models （Bederson et al., 1986a; Longa et al., 1989）. In human patients, ischemic stroke typically results from thrombotic or embolic occlusion of a major cerebral artery, usually the mid- dle cerebral artery （MCA）. Experimental focal cerebral ischemia models have been employed to mimic human stroke （Durukan and Tatlisumak, 2007）. Rodent models of focal cerebral ischemia that do not require craniotomy have been developed using intraluminal suture occlusion of the MCA （MCA occlusion, MCAO）（Rosamond et al., 2008）. Furthermore, mouse MCAO models have been wide- ly used and extended to genetic studies of cell death or recovery mechanisms （Liu and McCullough, 2011）. Genetically engineered mouse stroke models are particularly useful for evaluation of isch- emic pathophysiology and the design of new prophylactic, neuro- protective, and therapeutic agents and interventions （Armstead et al., 2010）. During the past two decades, MCAO surgical techniques have been developed that do not reveal surgical techniques for mouse MCAO model engineering. Therefore, we compared MCAO surgical methods in rats and mice.

关键词： MCAO CCA Middle cerebral artery occlusion methods in rat versus mouse model of transient focal cerebral ischemic stroke

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Incidence, prevalence and risk of stroke in patients with Takayasu arteritis: a nationwide population-based study in South Korea

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Stroke & Vascular Neurology 2022年第2期7卷 149-157页

作者： Sung Soo Ahn minkyung Han Yong-Beom Park Inkyung Jung Sang-Won lee Department of Internal Medicine Yongin Severance HospitalYonsei University College of MedicineYonginSouth Korea Biostatistics Collaboration Unit Department of Biomedical Systems InformaticsYonsei University College of MedicineSeoulSouth Korea Division of Rheumatology Department of Internal MedicineYonsei University College of MedicineSeoulSouth Korea Institute for Immunology and Immunological Diseases Yonsei University College of MedicineSeoulSouth Korea Division of Biostatistics Department of Biomedical Systems InformaticsYonsei University College of MedicineSeoulSouth Korea

Background Takayasu arteritis(TAK)is a disease associated with increased risk of cardiovascular complications.We aimed to evaluate the incidence,prevalence and risk of stroke in patients with TAK.Methods Data from 1065 patients were obtained from a national database(2010–2018).The annual incidence and prevalence per 100000 persons were estimated using the registration population in the midst of every year,and the standardised incidence ratio(SIR)of stroke was compared with the general population based on the data from the 2006 national report for cardiovascular and cerebrovascular diseases.Age-adjusted incidence rate ratio(IRR)of stroke based on the time interval after diagnosis was also calculated.A time-dependent Cox regression was conducted to investigate predictive factors of stroke.Results The overall incidence rate of TAK ranged between 0.2 and 0.3/100000 person-years annually;the prevalence of TAK gradually increased,reaching 3.25/100000 person-years in 2018.Seventy-three(6.9%)patients experienced stroke during follow-up,and the risk of developing stroke was higher than the general population(overall SIR 7.39,95%CI 5.79 to 9.29;men:SIR 5.70,95%CI 2.84 to 10.20;women:SIR 7.06,95%CI 5.41 to 9.05).Most stroke events(90.9%)were cerebral infarction for men,whereas the proportion of cerebral infarction was lower(62.9%)in women.Over half of stroke events occurred within 6 months after diagnosis,and stroke was more common within 6 months of diagnosis compared with after 3 years in women(IRR 13.46,95%CI 6.86 to 26.40).In Cox regression analysis,age was the sole predictor of stroke(adjusted HR 1.02,95%CI 1.00 to 1.04,p=0.043).Conclusions The annual incidence of TAK was similar to the previous studies from Asia,and the risk of stroke increased in TAK.Different patterns of subtype and incidence of stroke were found according to sex,although age was the only predictor.

关键词： prevalence patients diagnosis

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Switchable diurnal radiative cooling by doped VO_(2)

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Opto-Electronic Advances 2021年第5期4卷 24-30页

作者： minkyung Kim Dasol lee Younghwan Yang Junsuk Rho Department of Mechanical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea.

This paper presents design and simulation of a switchable radiative cooler that exploits phase transition in vanadium di-oxide to turn on and off in response to temperature.The cooler consists of an emitter and a solar reflector separated by a spacer.The emitter and the reflector play a role of emitting energy in mid-infrared and blocking incoming solar energy in ultraviolet to near-infrared regime,respectively.Because of the phase transition of doped vanadium dioxide at room tem-perature,the emitter radiates its thermal energy only when the temperature is above the phase transition temperature.The feasibility of cooling is simulated using real outdoor conditions.We confirme that the switchable cooler can keep a desired temperature,despite change in environmental conditions.

关键词： phase change material photonic crystal passive thermoregulation switchable radiative cooling Fabry-Pérot resonance

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Hyperbolic metamaterials: fusing artificial structures to natural 2D materials

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eLight 2022年第1期2卷 1-23页

作者： Dasol lee Sunae So Guangwei Hu minkyung Kim Trevon Badloe Hanlyun Cho Jaekyung Kim Hongyoon Kim Cheng‑Wei Qiu Junsuk Rho Department of Mechanical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Department of Biomedical Engineering Yonsei UniversityWonju 26493Republic of Korea Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea POSCO-POSTECH-RIST Convergence Research Center for Flat Optics and Metaphotonics Pohang 37673Republic of Korea.

Optical metamaterials have presented an innovative method of manipulating light.Hyperbolic metamaterials have an extremely high anisotropy with a hyperbolic dispersion relation.They are able to support high-k modes and exhibit a high density of states which produce distinctive properties that have been exploited in various applications,such as super-resolution imaging,negative refraction,and enhanced emission control.Here,state-of-the-art hyperbolic metamaterials are reviewed,starting from the fundamental principles to applications of artificially structured hyperbolic media to suggest ways to fuse natural two-dimensional hyperbolic materials.The review concludes by indicating the current challenges and our vision for future applications of hyperbolic metamaterials.

关键词： Hyperbolic metamaterials High resolution optical imaging Nanoscale lithography Light propagation and manipulation Spontaneous emission engineering Natural 2D materials

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Genome-wide SNP discovery and core marker sets for assessment of genetic variations in cultivated pumpkin(Cucurbita spp.)

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Horticulture Research 2020年第1期7卷 1139-1148页

作者： Nam Ngoc Nguyen minkyung Kim Jin-Kee Jung Eun-Jo Shim Sang-Min Chung Younghoon Park Gung Pyo lee Sung-Chur Sim Department of Bioresources Engineering Sejong UniversitySeoul 05006South Korea Seed Testing and Research Center Korea Seed&Variety ServiceGimcheon 39660South Korea Department of Life Sciences Dongguk UniversitySeoul 04620South Korea Department of Horticultural Bioscience Pusan National UniversityMiryang 50463South Korea Department of Plant Science and Technology Chung-Ang UniversityAnsung 17546South Korea Plant Engineering Research Institute Sejong UniversitySeoul 05006South Korea

Three pumpkin species Cucurbita maxima,C.moschata,and C.pepo are commonly cultivated worldwide.To identify genome-wide SNPs in these cultivated pumpkin species,we collected 48 F1 cultivars consisting of 40 intraspecific hybrids(15 C.maxima,18 C.moschata,and 7 C.pepo)and 8 interspecific hybrids(C.maxima x C.moschata).Genotyping by sequencing identified a total of 37,869 confident SNPs in this collection.These SNPs were filtered to generate a subset of 400 SNPs based on polymorphism and genome distribution.Of the 400 SNPs,288 were used to genotype an additional 188 accessions(94 F1 cultivars,50 breeding lines,and 44 landraces)with a SNP array-based platform.Reliable polymorphisms were observed in 224 SNPs(78.0%)and were used to assess genetic variations between and within the four predefined populations in 223 cultivated pumpkin accessions.Both principal component analysis and UPGMA clustering found four major clusters representing three pumpkin species and interspecific hybrids.This genetic differentiation was supported by pairwise Fst and Nei’s genetic distance.The interspecific hybrids showed a higher level of genetic diversity relative to the other three populations.Of the 224 SNPs,five subsets of 192,96,48,24,and 12 markers were evaluated for variety identification.The 192,96,and 48 marker sets identified 204(91.5%),190(85.2%),and 141(63.2%)of the 223 accessions,respectively,while other subsets showed<25%of variety identification rates.These SNP markers provide a molecular tool with many applications for genetics and breeding in cultivated pumpkin.

关键词： breeding cultivar Cucurbita

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Multiple-patterning colloidal lithography-implemented scalable manufacturing of heat-tolerant titanium nitride broadband absorbers in the visible to near-infrared

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Microsystems & Nanoengineering 2021年第2期7卷 51-58页

作者： Dasol lee Myeongcheol Go minkyung Kim Junho Jang Chungryong Choi Jin Kon Kim Junsuk Rho Department of Mechanical Engineering Pohang University of Science and Technology(POSTECH)Pohang37673Republic of Korea Department of Chemical Engineering Pohang University of Science and Technology(POSTECH)Pohang37673Republic of Korea National Institute of Nanomaterials Technology(NINT) Pohang37673Republic of Korea

Broadband perfect absorbers have been intensively researched for decades because of their near-perfect absorption optical property that can be applied to diverse applications. Unfortunately, achieving large-scale and heat-tolerant absorbers has been remained challenging work because of costly and time-consuming lithography methods and thermolability of materials, respectively. Here, we demonstrate a thermally robust titanium nitride broadband absorber with >95% absorption efficiency in the visible and near-infrared region (400–900 nm). A relatively large-scale (2.5 cm × 2.5 cm) absorber device is fabricated by using a fabrication technique of multiple-patterning colloidal lithography. The optical properties of the absorber are still maintained even after heating at the temperatures >600 ∘C. Such a large-scale, heat-tolerant, and broadband near-perfect absorber will provide further useful applications in solar thermophotovoltaics, stealth, and absorption controlling in high-temperature conditions.

关键词： absorber titanium absorption

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