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DSN-BR-Based Online Inspection Method and Application for Surface Defects of Pharmaceutical Products in Aluminum-Plastic Blister Packages

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Chinese Journal of Mechanical Engineering 2024年第4期 207-227页

作者： mingzhou liu Yu Gong Xiaoqiao Wang Conghu liu Jing Hu School of Mechanical Engineering Hefei University of Technology School of Mechanical and Electronic Engineering Suzhou University

Ensuring high product quality is of paramount importance in pharmaceutical drug manufacturing, as it is subject to rigorous regulatory practices. This study presents a research focused on the development of an on-line detection method and system for identifying surface defects in pharmaceutical products packaged in aluminum-plastic ***, the aluminum-plastic blister packages exhibit multi-scale features and inter-class indistinction. To address this, the deep semantic network with boundary refinement(DSN-BR) model is proposed, which leverages semantic segmentation domain knowledge, to accurately segment the defects in pixel level. Additionally, a specialized image acquisition module that minimizes the impact of ambient light is established, ensuring high-quality image capture. Finally, the image acquisition module, image detection module, and data management module are designed to construct a comprehensive online surface defect detection system. To validate the effectiveness of our approach,we employ a real dataset for instance verification on the implemented system. The experimental results substantiate the outstanding performance of the DSN-BR, achieving the mean intersection over union(MIoU) of 90.5%. Furthermore, the proposed system achieves an inference speed of up to 14.12 f/s, while attaining an F1-Score of 98.25%.These results demonstrate that the system meets the actual needs of the enterprise and provides theoretical and methodological support for intelligent inspection of product surface quality. By standardizing the control process of pharmaceutical manufacturing and improving the management capability of the manufacturing process, our approach holds significant market application prospects.

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Hybrid heuristic algorithm for multi-objective scheduling problem

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Journal of Systems Engineering and Electronics 2019年第2期30卷 327-342页

作者： PENG Jian'gang liu mingzhou ZHANG Xi LING Lin School of Mechanical Engineering Hefei University of Technology

This research provides academic and practical contributions. From a theoretical standpoint, a hybrid harmony search(HS)algorithm, namely the oppositional global-based HS(OGHS), is proposed for solving the multi-objective flexible job-shop scheduling problems(MOFJSPs) to minimize makespan, total machine workload and critical machine workload. An initialization program embedded in opposition-based learning(OBL) is developed for enabling the individuals to scatter in a well-distributed manner in the initial harmony memory(HM). In addition, the recursive halving technique based on opposite number is employed for shrinking the neighbourhood space in the searching phase of the OGHS. From a practice-related standpoint, a type of dual vector code technique is introduced for allowing the OGHS algorithm to adapt the discrete nature of the MOFJSP. Two practical techniques, namely Pareto optimality and technique for order preference by similarity to an ideal solution(TOPSIS), are implemented for solving the ***, the algorithm performance is tested by using different strategies, including OBL and recursive halving, and the OGHS is compared with existing algorithms in the latest *** results on representative examples validate the performance of the proposed algorithm for solving the MOFJSP.

关键词： flexible job-shop scheduling harmony search (HS) algorithm Pareto optimality opposition-based learning

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Dynamic Prediction Method of Production Logistics Bottleneck Based on Bottleneck Index

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Chinese Journal of Mechanical Engineering 2009年第5期22卷 710-716页

作者： liu mingzhou TANG Juan GE Maogen JIANG Zengqiang HU Jing LING Lin School of Mechanical and Automotive Engineering Hefei University of Technology Hefei 230009 China

In modern manufacturing pattern, there are many uncertain factors in the modern manufacturing process, such as changes of product attribute, changes of manufacturing resources＇ state, and so on, which cause production logistics bottleneck frequently shift, and make decisions of production planning and control based on formed bottleneck deviated from practical production process. Considering these factors, present researches mainly apply afterwards control to optimize production process to passively adapt to bottleneck changes If the direction of bottleneck shifting can be accurately forecasted, the transition from afterwards control of chasing bottleneck to beforehand control can be realized. Therefore, aiming at the phenomenon of production logistics bottleneck shifting under uncertain manufacturing circumstances, this paper starts off with dynamic property of capability and requirement and then builds the concepts of bottleneck degree and bottleneck index to describe dynamic bottleneck characteristic of production unit; taken production capability, production load and quality assurance capability into consideration, mathematical model of bottleneck index is established to measure bottleneck degree accurately, consequently, quantitative research on mechanism of production logistics shifting is achieved. Based on bottleneck index, the prediction model of production logistics bottleneck is founded to predict dynamic change of bottleneck accurately. Finally, an example of forecasting and monitoring the production logistics bottleneck in one manufacturing shop is given to testify the validation and practicability of the prediction method.

关键词： production logistics bottleneck shifting quality assurance capability bottleneck index prediction model

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TP439钢带冷弯成型性能影响因素分析

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钢管 2024年第3期53卷 79-83页

作者：刘明洲方焰兵吴俊洁孙炎张杰伟浙江久立特材科技股份有限公司·浙江省核电用高性能管材成形工程技术研究中心浙江湖州313028

使用两种相同厚度但不同制造工艺和成分的TP439钢带,采用相同的冷弯成型工艺生产同规格的产品,通过检测和分析金相组织、残余应力(C型法)、拉伸和硬度性能,发现影响TP439钢带冷弯成型性能的主要因素是化学成分和终轧温度。其中化学成分... 详细信息

使用两种相同厚度但不同制造工艺和成分的TP439钢带,采用相同的冷弯成型工艺生产同规格的产品,通过检测和分析金相组织、残余应力(C型法)、拉伸和硬度性能,发现影响TP439钢带冷弯成型性能的主要因素是化学成分和终轧温度。其中化学成分中C和N影响较大,主要影响钢带的硬度、强度和延伸率;终轧温度主要影响钢带晶粒度;低硬度、低屈服强度、高延伸率和细晶粒度有利于冷弯成型。通过对上述影响因素的分析研究,可为冷弯成型用TP439钢带的性能控制提供指导。

关键词：冷弯成型 TP439 残余应力终轧温度

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Secular trends of asthma mortality in China and the United States from 1990 to 2019

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Chinese Medical Journal 2024年第3期137卷 273-282页

作者： Xiaochen Li mingzhou Guo Yang Niu Min Xie Xiansheng liu Department of Pulmonary and Critical Care Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430030China NHC Key Laboratory of Respiratory Diseases WuhanHubei 430030China

Background:Asthma imposes a large healthcare burden in China and the United States(US).However,the trends of asthma mortality and the relative risk factors have not been comparatively analyzed between the *** aim of this study was to compare the mortality and risk factors between China and the ***:The deaths,and mortality rates of asthma in China and the US during 1990–2019 were obtained from the Global Burden of Disease Study *** age–period–cohort model was used to estimate these mortality rates based on a log-linear scale with additive age,period,and cohort *** population attributable fractions of risk factors for asthma were ***:In 1990–2019,the asthma mortality rate was higher in China than in the *** crude and age-standardized asthma mortality rates trended downward in both China and the US from 1990 to *** decline in mortality was more obvious in *** gap between the two countries was narrowing.A sex difference in asthma mortality was observed with higher mortality in males in China and females in the *** age effects showed that mortality increased with age in adults older than 20 years,particularly in the *** trends were generally observed in the period and cohort rate ratios in both countries,with China experiencing a more obvious *** and high body mass index(BMI)were the leading risk factors for asthma mortality in China and the US,*** attributable to occupational asthmagens and smoking decreased the most in China and the US,***:In 1990–2019,the asthma mortality rate was higher in China than in the US;however,the mortality gap has *** increased with age in *** improvements in asthma death risk with period and birth cohort were more obvious in China than in the ***,high BMI,and aging are major health problems associated with asthma *** role of occupational asthmagens in asthma mortality under

关键词： Asthma Mortality Global disease burden China the United States Age–period–cohort model

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Intense and Superflat White Laser with 700-nm 3-dB Bandwidth and 1-mJ Pulse Energy Enabling Single-Shot Subpicosecond Pulse Laser Spectroscopy

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Research 2024年第2期6卷 319-327页

作者： Lihong Hong Haiyao Yang Liqiang liu mingzhou Li Yuanyuan liu Baoqin Chen Huakang Yu Wenbo Ju Zhi-Yuan Li School of Physics and Optoelectronics South China University of TechnologyGuangzhou 510641China State Key Laboratory of Luminescent Materials and Devices South China University of TechnologyGuangzhou 510640China

An optical spectrometer is a basic spectral instrument that probes microscopic physical and chemical properties of macroscopic objects but generally suffers from difficulty in broadband time-resolved *** this work,we report the creation of ultrabroadband white-light laser with a 3-dB bandwidth covering 385 to 1,080 nm,pulse energy of 1.07 mJ,and pulse duration of several hundred femtoseconds by passing 3-mJ pulse energy,50-fs pulse duration Ti:Sapphire pulse laser through a cascaded fused silica plate and chirped periodically poled lithium niobate *** utilize this unprecedented superflat,ultrabroadband,and intense femtosecond laser light source to build a single-shot(i.e.,single-pulse)subpicosecond pulse laser ultraviolet-visible-near-infrared spectrometer and successfully measure various atomic and molecular absorption *** single-shot ultrafast spectrometer may open up a frontier to monitor simultaneously the ultrafast dynamics of multiple physical and chemical processes in various microscopic systems.

关键词： Pulse utilize frontier

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ZL28型滤棒成型机组刀盘喇叭嘴机构模型的建立及应用

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机械工程师 2024年第8期 80-84,89页

作者：刘明周李忱臻李庆林吴孔友施永清张松涛赵德林许昌烟草机械有限责任公司研发中心河南许昌461002 北京达特集成技术有限责任公司北京100176

为了将引进的ZL28型双通道纤维滤棒成型机组技术消化吸收,分析了ZL28型纤维滤棒成型机组滤棒切割装置的结构原理,根据切刀、喇叭嘴、滤条之间的位置关系,利用Creo软件仿真模拟出ZL28型纤维滤棒成型机组双通道滤棒切割装置的运动规律,建... 详细信息

为了将引进的ZL28型双通道纤维滤棒成型机组技术消化吸收,分析了ZL28型纤维滤棒成型机组滤棒切割装置的结构原理,根据切刀、喇叭嘴、滤条之间的位置关系,利用Creo软件仿真模拟出ZL28型纤维滤棒成型机组双通道滤棒切割装置的运动规律,建立ZL28型纤维滤棒成型机组滤棒切割装置的几何模型,从而推导出ZL28型纤维滤棒成型机组滤棒切割装置的数学模型,得出常用的滤棒长度与刀盘倾角、喇叭嘴旋转直径之间的关系和数值。将求解得到的数值与转让技术参数进行对比,等于或接近修正后的设计技术参数,证明所述方法正确,可以为生产多品规的滤棒提供技术支持。

关键词： ZL28型双通道滤棒成型机组切割装置喇叭嘴

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基于分层任务网络的云制造任务分解方法

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中国机械工程 2017年第8期28卷 924-930页

作者：刘明周王强凌琳合肥工业大学机械与汽车工程学院合肥230009

提出了一种基于顺序任务分解的云制造任务分解算法。首先给出云制造任务描述模型以及任务约束结构的相关定义,对制造任务粒度分析方法、制造任务内聚性度量方法和制造任务相关性度量方法进行了研究。然后,采用递归分解算法对任务进行优... 详细信息

提出了一种基于顺序任务分解的云制造任务分解算法。首先给出云制造任务描述模型以及任务约束结构的相关定义,对制造任务粒度分析方法、制造任务内聚性度量方法和制造任务相关性度量方法进行了研究。然后,采用递归分解算法对任务进行优化分解,并在分解过程中考虑任务的资源匹配问题。最后,以某变速箱试制任务分解为实例验证了所提方法的可行性和有效性。

关键词：云制造任务分解任务粒度分层任务网络

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海底治理的特征与世界政治新理念

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学海 2023年第3期 88-95页

作者：刘明周华中师范大学政治与国际关系学院暨政治学部国际政治研究中心武汉430079

全球海底治理在建构过程中形成了三个典型特征。首先,以国际海底管理局为核心的相对有效治理;其次,发展中国家在治理机制建设中发挥了主导地位;最后,各方博弈形成的平行开发制,即国际海底管理局与民族国家同时为企业的开发活动提供授权... 详细信息

全球海底治理在建构过程中形成了三个典型特征。首先,以国际海底管理局为核心的相对有效治理;其次,发展中国家在治理机制建设中发挥了主导地位;最后,各方博弈形成的平行开发制,即国际海底管理局与民族国家同时为企业的开发活动提供授权。海底治理的进程揭示了世界政治的三个关键性转变,一是权力政治在新的时代相对弱化,二是世界政治中的伦理性色彩更加凸显,三是世界政治正展现出超越民族国家的人类共生性特征。在这个新旧杂陈的时代,海洋命运共同体的理念暗合世界政治的新特征,有望为海底治理的推进提供助力。

关键词：海底治理国际海底管理局权力政治人类共同继承财产海洋命运共同体

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基于实时信息驱动的生产车间运行驾驶舱研究及实现

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计算机集成制造系统 2015年第8期21卷 2052-2062页

作者：刘明周王强凌琳合肥工业大学机械与汽车工程学院安徽合肥230009

为提高车间生产管理的透明化程度,从生产车间运行状态监控的角度出发,提出一种基于实时信息驱动的生产车间运行驾驶舱体系架构及运行模式,并对其关键实现技术进行研究。通过构建生产车间多层次运行指标体系,使生产监控任务明细化。基于... 详细信息

为提高车间生产管理的透明化程度,从生产车间运行状态监控的角度出发,提出一种基于实时信息驱动的生产车间运行驾驶舱体系架构及运行模式,并对其关键实现技术进行研究。通过构建生产车间多层次运行指标体系,使生产监控任务明细化。基于可拓展标记语言的规则映射方法实现了生产过程多源异构信息的同构化处理,为系统提供了统一可靠的数据支撑。通过构建生产运行指标通用模型,使系统能够灵活适应各类业务及需求变更,从而提高系统的可拓展性和适应性。基于上述系统体系架构及实现方法,开发了原型系统并应用于某自动变速器装配车间,验证了该方法的可行性和有效性。

关键词：可视化驾驶舱信息集成规则映射

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