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Integrating lipidomics and gut microbiota to study the anti-hyperlipidemia effect of Sargentodoxae Caulis extract

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Traditional Medicine Research 2025年第1期10卷 1-11页

作者： Xiao-Xiao Zhang Li jia Xiu-Jun Zhan Charity Ngina Qing-Rui Zhang Xiao-Ge Li Qi-Bao jiang Shi Bai Miao-Miao jiang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjin 301617China Haihe Laboratory of Modern Chinese Medicine Tianjin 301617China School of Medicine Taizhou UniversityTaizhou 318000China.

Background:Sargentodoxae Caulis(SC)is the vine stem of Sargentodoxa Cuneata(Oliv.)Rehd.&*** in ***,and it in traditional Chinese medicine has been known for promoting blood circulation and removing blood stasis as recorded in the ancient book“Illustrated Classics of Materia Medica”.It has been used effectively to treat blood stasis too in modern clinical ***,the anti-hyperlipidemia effect of SC is not fully *** paper aims at exploring the use of SC stems to improve the balance of blood lipids in the body,and its new role in treating ***:The effects of SC extract on hyperlipidemia were explored by combining lipidomics and gut ***,we explored the potential mechanism of SC in treating hyperlipidemia by pathway ***:The results showed that the stem extract of SC could restore the physiological and biochemical indices of hyperlipidemia in mice,as well as repair the morphological and structural damage to *** to the Model group,the SC extract significantly reduced the liver index,epididymal fat index,and Lee’s *** also significantly decreased serum levels of total cholesterol,triglycerides,low-density lipoprotein cholesterol,peroxisome proliferator-activated receptor gamma(PPAR-γ),D-lactate,and free fatty acids,while significantly increasing the relative content of peroxisome proliferator-activated receptor alpha(PPAR-α).These changes were statistically ***-targeted lipidomics,based on LC-MS,were utilized to investigate the lipid metabolism characteristics in serum,liver,and epididymal fat of the *** was observed that,compared to the blank group,the Model group exhibited significant changes primarily in glycerol lipids and *** treatment group also displayed alterations in these lipids.A total of 38,81,and 27 differential lipids were identified in serum,liver,and epididymal fat samples,*** these,14 common differenti

关键词： hyperlipidemia Sargentodoxae Caulis lipidomics intestinal flora

Mechanical Properties of Interlocked-ring Polymers: A Molecular Dynamics Simulation Study

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Chinese Journal of Polymer Science 2019年第12期37卷 1298-1304,I0008页

作者： Zheng-Tao Wu jia-jia Zhou College of Engineering Zhejiang Normal UniversityJinhua 321004China School of Chemistry Beihang UniversityBeijing 100191China

Interlocked-ring polymers,also known as polycatenanes,possess an interesting molecular *** polymers are composed of many interlocked rings in a linear *** topological constrain between neighboring rings distinguishes the interlockedring polymer from its linear *** we present extensive molecular dynamic simulations on the interlocked-ring polymers and analyze the static properties of the *** applying external forces to the polymer,we also study the force-extension curves of the polymer,which provides rich information about the mechanical properties of the interlockedring polymers.

关键词： Poly catenanes Molecular dynamics simulation Force-extension Entanglement

A PRACTICAL PARALLEL DIFFERENCE SCHEME FOR PARABOLIC EQUATIONS

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Journal of Computational Mathematics 2004年第1期22卷 55-60页

作者： jia-quanGao RDCPS InstituteofSoftwareChineseAcademyofSciencesP.O.Box8718Beijing100080China

A practical parallel difference scheme for parabolic equations is constructed as follows:to decompose the domain Ω into some overlapping subdomains, take flux of the last time layer as Neumann boundary conditions for the time layer on inner boundary points of subdomains, solve it with the fully implicit scheme on each subdomain, then take correspondent values of its neighbor subdomains as its values for inner boundary points of each subdomain and mean of its neighbor subdomain and itself at overlapping *** scheme is unconditionally convergent. Though its truncation error is O(T + h), the convergent order for the solution can be improved to O(T + h^2).

关键词： Explicit-implicit Parabolic equation Parallel difference scheme Segment

Flexible crystalline silicon solar cells leading to the beginning of the mobile energy era

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Science China Materials 2023年第8期66卷 3373-3374页

作者： Rui jia Institute of Microelectronics of Chinese Academy of Sciences Beijing 100029China University of Chinese Academy of Sciences Beijing 100029China

Monocrystalline silicon solar cells are currently the fastestdeveloping type of solar *** have the advantages of low price,long service life,mature manufacture technology and high conversion *** silicon solar cells account for more than 95%of the photovoltaic market in the *** the crystalline silicon solar cells,the heterojunction cell(HJT)has achieved the highest efficiency of single crystalline silicon solar cell—26.81%[1].However,heterojunction cells,like other crystalline silicon cells,cannot be bent when the silicon substrate is thick,thus limiting their applications in many fields.

关键词： crystalline price limiting

乙酰丙酮铱Ir(acac)_(3)电子结构及光学性质的理论研究

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原子与分子物理学报 2025年第1期42卷 1-7页

作者：樊依佳蔚娇娇郭家成陈扬尹杜恭贺西北工业大学伦敦玛丽女王大学工程学院西安710129 西安邮电大学理学院西安710121

乙酰丙酮铱是一种由过渡金属Ir与乙酰丙酮酸(acetylcaetonato)有机部分组成的过渡金属有机配合物,它是一种重要的绿光磷光材料,同时其也是多种铱系发光材料的组成部分.采用密度泛函理论(DFT)对Ir(acac)_(3)单体及其二聚物的基态几何结... 详细信息

乙酰丙酮铱是一种由过渡金属Ir与乙酰丙酮酸(acetylcaetonato)有机部分组成的过渡金属有机配合物,它是一种重要的绿光磷光材料,同时其也是多种铱系发光材料的组成部分.采用密度泛函理论(DFT)对Ir(acac)_(3)单体及其二聚物的基态几何结构进行了优化,在此基础上考察了它们的振动和红外光谱,并使用CIS方法对它们的激发态性质进行了理论研究.计算得到的单体和二聚物的吸收光谱均在紫外波段,单体的主要吸收峰有260 nm,350 nm,414 nm,二聚物的主要吸收峰有299 nm,353 nm,401 nm.计算得到了二者在乙腈CH_(3)CN溶液中的吸收光谱,与它们气相情况的结果相比,溶剂极性的影响使得电子吸收谱发生蓝移.计算结果表明Horst Kunkely和Arnd Vogler所得光谱中既含有单体的特征光谱,又含有二聚体的特征光谱,证明实验溶液中同时存在乙酰丙酮铱的低聚物,并且二者的组分比能被合理推算.最后,对多聚体的形成机理作了简单讨论.

关键词： Ir(acac)_(3) 密度泛函理论(DFT) CIS 电子吸收光谱溶液效应

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Paleontology: advancing China's international leadership

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National Science Review 2019年第1期6卷 171-176页

作者： Hepeng jia Writes for NSR from Beijing

In recent years, Chinese scientists have achieved significant progress in paleontological discoveries and scientific studies. Series of studies published in top journals, such as Science, Nature and Proceedings of the National Academy of Sciences of the United States of America(PNAS), have astonished the world by presenting beautiful fossils that furnish robust evidence to enrich the understanding of organismic evolution, major extinctions and stratigraphy. It has been portrayed as the heyday in the paleontology of China. What is the status of the field?What factors have caused the avalanche of fossil discoveries in China? What implications can these new discoveries

关键词： Paleontology advancing China’s international leadership

Linear generalized synchronization of chaotic systems with uncertain parameters

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Journal of Systems Engineering and Electronics 2008年第4期19卷 779-784页

作者： jia Zhen Dept. of Mathematics and Physics Guilin Univ. of Technology Guilin 541004 P. R. China

A more general form of projective synchronization, so called linear generalized synchronization （LGS） is proposed, which includes the generalized projective synchronization （GPS） and the hybrid projective synchronization （HPS） as its special cases, Based on the adaptive technique and Lyapunov stability theory, a general method for achieving the LGS between two chaotic or hyperehaotic systems with uncertain parameters in any scaling matrix is presented. Some numerical simulations are provided to show the effectiveness and feasibility of the proposed synchronization method.

关键词： generalized synchronization chaotic system hyperchaotic system uncertain parameter adaptive technique.

ON APPROXIMATION OF LAPLACIAN EIGENPROBLEM OVER A REGULAR HEXAGON WITH ZERO BOUNDARY CONDITIONS

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Journal of Computational Mathematics 2004年第2期22卷 275-286页

作者： jia-changSun ParallelComputingDivision InstituteofSoftwareChineseAcademyofSciencesBeijing100080China

In my earlier paper [4], an eigen-decompositions of the Laplacian operator is given on a unit regular hexagon with periodic boundary conditions. Since an exact decomposition with Dirichlet boundary conditions has not been explored in terms of any elementary *** this paper, we investigate an approximate eigen-decomposition. The function space,corresponding all eigenfunction, have been decomposed into four orthogonal *** of the first eight smallest eigenvalues and related orthogonal functions are given. In particulary we obtain an approximate value of the smallest eigenvalue λ1～29/40π^2= 7.1555, the absolute error is less than 0.0001.

关键词： Dirichlet boundary conditions Laplacian eigen-decomposition Regular hexagon domain

A NOTE ON THE MODEL REFERENCE ADAPTIVE CONTROL OF LINEAR PARABOLIC SYSTEMS WITH CONSTANT COEFFICIENTS

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Journal of Systems Science & Complexity 2011年第6期24卷 1110-1117页

作者： Chaohua jia School of Mathematics and Systems Science Beihang University Beijing 100191 China LMIB of the Ministry of Education Beijing 100191 China

The problem of constructing a model reference adaptive control law for an uncertain 1- dimensional parabolic system with one constant coefficient is considered in this paper. Adaptive control law are obtained by Lyapunov redesign method. The energy method for parabolic systems and the Agmon＇s inequality are applied in the analysis, which leads to a stronger result than that of Hong and Bentsman （Automatica, 1994）.

关键词： Adaptive law distributed parameter systems model reference adaptive control parabolic system.