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Diethyl　Tartrate　on　Polystyrene　Bead　as　Chiral　Stationary　Phase　in　Liquid　Chromatography

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Chinese Chemical Letters 1996年第11期7卷 1035-1036页

作者： Liu, QY Wu, XJ he, JG Liu, GQ CHINESE ACAD SCI INST CHEMBEIJING 100080PEOPLES R CHINA

L0-(+)-diethyl tartrate was bound to hydroxymethyl polystyrene bead as a chiral stationaryphase in high-performance liquid chromatography(HPLC) for the resolution of pharmaceuticallyracemic compounds, such as D,L-amyg... 详细信息

关键词： Tartrate Bead

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Effects and Mechanisms of RE on Impact Toughness and Fracture Toughness of Clean heavy Rail Steel

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Journal of Iron and Steel Research International 2011年第3期18卷 52-58页

作者： LIU Cheng-jun HUANG Ya-he JIANG Mao-fa School of Materials and Metallurgy Northeastern UniversityShenyang 110004LiaoningChina

Clean high carbon heavy rail steel was prepared by the process of vacuum induction furnace smelting,forging and *** of RE on the impact toughness and fracture toughness for clean high carbon steel were *** addition,the appropriate range of RE content for clean high carbon steel was *** the austenite grain size and pearlite lamellar spacing decreased due to small amount of RE,consequently the impact toughness and fracture toughness were improved *** the RE content exceeded a critical value,the pearlite lamellar spacing was increased,because RE was segregated on the austenite grain boundaries,damaged the orientation relationship of pearlite transformation,caused the disorder growth and morphology degenerating of *** the increasing of RE content,both the impact toughness and fracture toughness of clean high carbon steel were gradually increased at first and then *** was found that when the RE content was between 0.0081% and 0.0088%,both the impact toughness and fracture toughness of clean high carbon heavy rail steel were the *** maximum ballistic work was 21.2 J（20 ℃） and 12.2 J（-20 ℃）,*** maximum plane-strain fracture toughness was 45.67 MPa·m1/2（20 ℃） and 37.04 MPa·m1/2（-20 ℃）,respectively.

关键词： rare earth high carbon steel heavy rail steel clean steel impact toughness fracture toughness

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Effect of Hydrolysis Catalysts on Structural Evaluation of Sol-Gel Derived Titania Nanocrystalline Powders

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Chinese Physics Letters 1995年第2期12卷 123-125页

作者： DING Xingzhao LUO Ju QI Zhenzhong he Yizhen Institute of Solid State Physics Academia SinicaHefei 230031

Effect of hydrolysis catalysts(HCl and C_(5)H_(8)O_(2))on structural evaluation of gelderived nanocrystalline TiO_(2) powders was *** temperature of the HCl catalyzed gel is about 200K lower than that of the C_(5)H_(8)O_(2) catalyzed *** in the later gel the anatase phase transforms to rutile at a lower temperature,and the transformation is completed in a much more narrow temperature range.

关键词： catalyzed hydrolysis narrow

Pyrene Excimer-based Bis-triazolyl Pyranoglycoligands as Specific Mercury Sensors

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Chinese Journal of Chemistry 2012年第12期30卷 2874-2878页

作者： he Xiaopeng Xie Juan Chen Guorong Chen Kaixian Key Laboratory for Advanced Materials & Institute of Fine Chemicals East China University of Science and Technology Shanghai 200237 China PPSM Institut d'Alembert ENS de Cachan CNRS UMR 8531 61 Avenue du pt Wilson F-94235 Cachan France State Key Laboratory of Drug Research Shanghai Institute ofMateria Medica Chinese Academy of Sciences Shanghai 201203 China

New C3,4-disubstituted bis-triazolyl glycoligands that feature a glucosyl or galactosyl scaffold incorporating two pyrenyl groups were synthesized via the Cu^1-catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction （Cue-AAC）. These compounds exert a major emission band corresponding to that of pyrene excimer and respond specifically to mercury with a markedly quenched fluorescence. The epimeric nature of the pyranoglycosyl scaffold is determined influential toward the selectivity of the sensors.

关键词： glycoligand click chemistry sugar mercury chemosensor

Optimization of parental RNAi conditions for hunchback gene in Locusta migratoria manilensis （Meyen）

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Insect Science 2010年第1期17卷 1-6页

作者： Zheng-Bo he Yue-Qing Cao Yu-Xian Xia Genetic Engineering Research Center College of Bioengineering Chongqing University Chongqing Engineering Research Center for Fungal Insecticides and Key Laboratory of Functional Gene and Regulation Technologies under Chongqing Municipal Education Commission Chongqing China

An investigation on the optimization of parental RNA interference （RNAi） conditions for hunchback （hb） gene in Locusta migratoria manilensis （Meyen） was conducted. Double stranded RNA （dsRNA） corresponding to hb gene was injected into haemocoel of female adults ofL. migratoria manilensis. Embryos developed from the eggs laid by the injected adults on the 7th day after eclosion showed observable effects of RNAi for hb. The silencing effect after delivery treatment of dsRNA for hb gene was maintained for more than 21 days. A significant decrease of hb transcripts was further confirmed by Northern blot analysis. The dose of dsRNA/insect at 2μg could trigger 96.9% RNAi effects, while silencing appeared to have no dependence on the size of dsRNA. Results suggest that parental RNAi could be employed to efficiently identify the developmental gene functions in L. migratoria manilensis.

关键词： hunchback Locusta migratoria manilensis parental RNA interference

Penumbra-targeted CircOGDH siRNA-loaded nanoparticles alleviate neuronal apoptosis in focal brain ischaemia

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Stroke & Vascular Neurology 2024年第2期9卷 134-144,I0396-I0413页

作者： Yanfang Liu Tianyuan Zhang Xing Zou Zhongwen Yuan Yufeng Li Jiankun Zang Niu he Lizhen he Anding Xu Dan Lu Department of Neurology and Stroke Center Jinan University First Affiliated HospitalGuangzhouGuangdongChina Department of Clinical Neuroscience Institute The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdongChina Key Lab of Guangzhou Basic and Translational Research of Pan-vascular Diseases The First Affiliated Hospital of Jinan UniversityGuangzhouChina

Background Nanoparticles(NPs)are a class of substances that can be loaded with therapeutic agents delivered to specific *** our earlier research,we identified a neuron-derived circular RNA(circRNA),circular oxoglutarate dehydrogenase(CircOGDH),as a promising therapeutic target for acute ischaemic *** study dedicated to explore a prospective preliminary strategy of CircOGDH-based NP delivered to the ischaemic penumbra region in middle cerebral artery occlusion/reperfusion(MCAO/R)*** Immunofluorescence in primary cortex neurons and in vivo fluorescence imaging revealed endocytosis of Poly(lactide-co-glycolide)(PLGA)poly amidoamine(PAMAM)@CircOGDH small interfering RNA(siRNA)*** blotting analysis and CCK8 assay were performed to evaluate the apoptotic level in ischaemic neurons treated with PLGA–PAMAM@CircOGDH siRNA *** reverse transcription PCR experiments,mice behaviour test,T2 MRI analysis,Nissl and TdT-mediated dUTP nick end labeling(TUNEL)co-staining were performed to evaluate the apoptosis level of ischaemic penumbra neurons in MCAO/R *** evaluation of NPs in MCAO/R mice was detected by blood routine examination,liver and kidney function examination and he *** PLGA–PAMAM@CircOGDH siRNA NPs were successfully *** of PLGA–PAMAM@CircOGDH siRNA NPs in ischaemic neurons alleviated neuronal apoptotic level in vitro and in ***,mice behaviour test showed that the neurological defects of MCAO/R mice were significantly alleviated after the tail injection of PLGA–PAMAM@CircOGDH siRNA NPs,and no toxic effects were *** In conclusion,our results suggest that PLGA–PAMAM@CircOGDH siRNA NPs can be delivered to the ischaemic penumbra region and alleviate neuron apoptosis in MCAO/R mice and in ischaemic neurons;therefore,our study provides a desirable approach for using circRNA-based NPs for the treatment of ischaemic stroke.

关键词： OGD routine loaded

Femtosecond Optical Pump Induced Enhancement of Terahertz Radiation from GaAs Surface

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Chinese Physics Letters 1995年第11期12卷 689-692页

作者： WANG Li he Wenguang YANG Guozheu ZHANG Xicheng Optical Physics Laboratory Institute of PhysicsAcademia SinicaBeijing 100080 Department of Physics Rensselaer Polytechnic InstituteToryNY 12180USA

Terahertz(THz)far infrared radiation with a subpicosecond pulse duration is generated from GaAs(100)surface illuminated by femtosecond laser *** illuminating the sample with another pump pulse,we observe an enhancement of THz emission.A mechanism of photocarriers trapping by impurities and defects in the depletion layer is proposed.

关键词： pump Femto pulse

Dependence of Quark Effective Mass on Gluon Propagators

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Communications in Theoretical Physics 2005年第4X期44卷 670-674页

作者： he Xiao-Rong ZHOU Li-Juan Wei-Xing Institute of Physical Science and Engineering Technology Guangxi University Nanning 530004 China Collaboration Group of Hadron Physics and Non-perturbative QCD Study Guangxi University of Technology Liuzhou 545006 China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator of Lanzhou Lanzhou 730000 China Institute of High Energy Physics the Chinese Academy of Sciences P.O. Box 918 Beijing 100049 China

Based on Dyson Schwinger Equations （DSEs） in the “rainbow” approximation, the dependence of quark effective mass on gluon propagator is investigated by use of three different phenomenological gluon propagators with two parameters, the strength parameter x and range parameter △. Our theoretical calculations for the quark effective mass Mf（p^2）, defined by the self-energy functions Af（p^2） and Bi（p%2） of the DSEs, show that the dynamically running quark effective mass is strongly dependent on gluon propagator. Therefore, because gluon propagator is completely unknown, the quark effective mass cannot be exactly determined theoretically.

关键词： quark mass gluon propagator DSEs QCD

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Thermal optimization and experimental research of high-speed universal pulverizer

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Advances in Manufacturing 2018年第1期6卷 83-94页

作者： Qiang he An-Ling Li Yuan Shen Li-Li Li School of Mechanical Engineering Anyang Institute ofTechnology Anyang 455000 Henan People's Republic ofChina

Because of high efficiency, energy conservation,simple operation, wide application range, and small size,the high-speed universal pulverizer has been well receivedby customers. However, its electrical motor can overheatwhen working, which hinders continuous operation of thepulverizer. In this study, a series of efforts were made toaddress this problem. Firstly, a detailed analysis of theworking principle of the pulverizer was conducted and anoptimization plan was proposed, consisting in punchingventilation holes on the surface of the original *** of the pulverizer flow field before and afteroptimization were performed. The hydrodynamic simula-tion results were used to conduct a steady state thermalanalysis of the pulverizer, investigating the influence of theflow field on heat transfer. Additionally, experimentalinvestigations were conducted on the pulverizer before andafter optimization in order to measure and compare theparameters （motor working temperature, wind speed andtemperature of the motor cooling system, vibration, noise,and pulverizing degree of the material） influencing theperformance of the pulverizer. The numerical simulationresults showed an increment in heat transfer caused byincrement in air flow volume and velocity when air wasinjected into the pulverizer through bottom and side *** results showed that the pulverizer with airinjection through holes had the best performance whentemperature, vibration, and refinement effect were consid-ered as performance indicators.

关键词： High-speed universal pulverizer Flow fieldsimulation Thermal analysis Pulverizing degree Vibration noise