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Composite excitation multi-extension direction defect magnetic flux leakage detection technology

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Journal of Measurement Science and Instrumentation 2022年第2期13卷 156-165页

作者： wei minghui TU Fengmiao ZHANG Peng JIANG Lixia JIANG Pengbo JING Yu School of Mechatronic Engineering Southwest Petroleum University Chengdu 610500 China Kensington Campus University of New South Wales Kensington 2052 NSW

In the traditional pipeline magnetic flux leakage(MFL)detection technology,circumferential or axial excitation is mainly used to excite the magnetic field of ***,the domestic and foreign pipeline detection devices currently in operation are mainly axial excitation MFL detection tools,in which circumferential cracks can be clearly identified,but the detection sensitivity of axial cracks is not high,thus forming a detection blind ***,a composite excitation multi-extension direction defect MFL detection method is proposed,which can realize the simultaneous detection of axial and circumferential *** the basis of the electromagnetic theory Maxwell equation and Biot Savart law,a mathematical model of circumferential and axial magnetization is firstly *** finite element simulation software is used to establish a model of a new type of magnetic flux leakage detection device,and a simulation analysis of crack detection in multiple extension directions is carried ***,under the conditions of the relationship model between the change rate of leakage magnetic field and external excitation intensity under unsaturated magnetization and the multi-stage coil magnetization model,the sample vehicle towing experiment is carried *** paper aims to analyze the feasibility and effectiveness of the new magnetic flux leakage detection device for detecting defects in different extension *** on the final experimental results,the new composite excitation multi extension direction leakage magnetic field detector has a good detection effect for defects in the axial and circumferential extension directions.

关键词： composite excitation magnetic flux leakage(MFL) multi-extension direction defect pipeline detection

QUANTITATIVE SUBSIDENCE ANALYSIS OFTHE TENSIVE BASIN AND COMPRESSIVEMOUNTAIN TYPE DIWA BASIN WITH IMPLICATIONS FOR EPISODIC TECTONIC MOVEMENT AND SEDIMENTATION

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Geotectonica et Metallogenia 1999年第2期23卷 125-133页

作者： Yang minghui and wei Yongpei(Department of Geology, Northwest University, Xi’ an 710069, China )

This paper presents a quantitative analysis of Jurassic-Quaternary basement subsidence in the Delingha basin, a tensile basin and compressive mountain type diwa basin, and corrected for local sediment loading. Subsidence patterns have been investigated for the effects of erosion induced uplift by means of analytical estimation. The history of the Delingha basin has been divided into four stages: 204(?)~130 Ma (SⅠ ), 130~95 Ma (SⅡ ), 67~35 Ma (SⅢ ) and 35~0 Ma (SⅣ ), recording episodic tectonics and sedimentation respectively.

关键词： Tensive basin and compressive mountain diwa basin subsidence analysis depositional system the northern Qaidam basin

道教在美国的本土化传播以美国道教协会为中心

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中国道教 2023年第4期 72-73页

作者：魏明慧中国道教协会

道教是中国土生土长的宗教,可以称作中华民族固有的传统宗教,是中国传统文化的重要组成部分。那么,根植于中国传统文化的道教在美国传播会是什么样的场景?东西方的文化差异明显,美国人能否理解中国文化。

关键词：道教协会中国传统文化文化差异东西方宗教中华民族

Plant-microbial interactions inspired the discovery of novel sesquiterpenoid dimeric skeletons of hidden natural products from Hibiscus tiliaceus

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Chinese Chemical Letters 2024年第10期35卷 312-316页

作者： Deli Chen Jiawen Li Xudong Xu Zhaocui Sun Yun Yang minghui Xu Hanqiao Liang Junshan Yang Hui Meng Guoxu Ma Jianhe wei Hainan Branch of the Institute of Medicinal Plant Development (Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine) Chinese Academy of Medical Sciences & Peking Union Medical College Institute of Medicinal Plant Development Chinese Academy of Medical Sciences & Peking Union Medical College School of Pharmaceutical Science Hainan Medical University Department of Biomedicine Beijing City University

Hidden natural products are representative of defensive strategies produced in vivo in diseased plants,a process that is induced by the plant immune *** first transcriptome library of uninfected and pathogen infected Hibiscus tiliaceus stems was constructed by transcriptome sequencing technology,genes related to cadinene-type sesquiterpenoid biosynthesis were screened and combined with ultra-performance liquid chromatography-quadrupole-time of flight mass spectrometry （UPLC-QTOF-MS） analysis data,which indicated pathological tissue had potential to produce novel carbon skeletons of cadinane sesquiterpenoid ***,two cadinane-derived sesquiterpenoid dimers with unprecedented carbon skeletons,hibisceusanols A （1） and B （2） were isolated for the first time from the stems of *** induced by plant-microbial *** structures and absolute configurations were unambiguously established by spectroscopy,advanced chemistry development （ACD） and electronic circular dichroism （ECD） *** 1 and 2 exhibited significant antitumor activity in vitro with half maximal inhibitory concentration (IC50) values of 2.3–7.2μmol/*** anticancer effect was generated via the induction of Hep G2 cell apoptosis by inhibiting the phosphatidylinositol 3-kinase （PI3K） pathway.

关键词： Anti-cancer Cadinane-derived sesquiterpenoid Hibiscus tiliaceus PI3K Plant-microbial interactions

Impact of metabolic dysfunction-associated steatotic liver disease on the efficacy of immunotherapy in patients with chronic hepatitis B-related hepatocellular carcinoma

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Cancer Biology & Medicine 2024年第9期21卷 813-825页

作者： Jiaxin Han Wentao Kuai Liu Yang Xuemei Tao Yuekui Wang minghui Zeng Yuqin Li Yuqiang Mi Ningning Zhang wei Lu Liang Xu Clinical School of the Tianjin Second People's Hospital Tianjin Medical University Department of Hepatology Tianjin Second People's Hospital Tianjin Institute of Hepatology Department of Hepatobiliary Oncology Liver Cancer Center Tianjin Medical University Cancer Institute & Hospital National Clinical Research Center for Cancer Key Laboratory of Cancer Prevention and TherapyTianjin Tianjin's Clinical Research Center for Cancer

Objective: To investigate the impact of metabolic dysfunction-associated steatotic liver disease(MASLD) on the efficacy of immune checkpoint inhibitor(ICI)-based therapy in patients with chronic hepatitis B(CHB)-related hepatocellular carcinoma(HCC).Methods: A total of 155 patients with CHB-related HCC who received ICI±based therapy(in the Department of Hepatology, Tianjin Second People's Hospital and Department of Hepatobiliary Oncology, Tianjin Medical University Cancer Institute & Hospital) between April 2021 and December 2023 were *** were divided into two groups: MASLD concurrent with CHB [MASLD-CHB](n = 38), and CHB(n = 117).Results: The median progression-free survival(PFS, 6.9 months vs.9.3 months; P = 0.001), progressive disease(57.89% vs.37.61%; P = 0.028), and disease control rate(42.11% vs.62.39%; P = 0.028) in the MASLD-CHB group were significantly worse than the CHB *** median overall survival was not *** percentage of CD4+PD1+(17.56% vs.8.89%; P < 0.001) and CD8+PD1+ T cells(10.50% vs.7.42%; P = 0.005) in patient samples from the MASLD-CHB group were significantly higher than the CHB *** MASLD [hazard ratio(HR) = 1.921; 95% CI, 1.138±3.245; P = 0.015] and alpha-fetoprotein levels after 3 months of treatment(HR = 2.412; 95% CI, 1.360±4.279; P = 0.003) were independent risk factors for PFS in all ***: ICI-based therapy in patients with CHB-related HCC and concurrent MASLD resulted in poorer efficacy and shorter PFS compared to patients with CHB-related HCC alone.

关键词： Metabolic dysfunction-associated steatotic liver disease chronic hepatitis B efficacy hepatocellular carcinoma immunotherapy

基于控制性能比较的非线性不对称系统预测控制

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化工学报 2012年第10期63卷 3183-3189页

作者：韦明辉罗雄麟冯爱祥中国石油大学自动化研究所北京102249

生产过程某些非线性系统常常表现出不对称动态特性,相对于其在工业工程中经常出现的理论研究特别是控制方法研究则十分有限。本文针对基于正反方向上的两个线性模型分别设计PID控制器的缺陷,提出根据正反方向上的线性模型分别设计相应... 详细信息

生产过程某些非线性系统常常表现出不对称动态特性,相对于其在工业工程中经常出现的理论研究特别是控制方法研究则十分有限。本文针对基于正反方向上的两个线性模型分别设计PID控制器的缺陷,提出根据正反方向上的线性模型分别设计相应的状态反馈预测控制器。在每一步的控制率计算中,正反方向的控制器分别计算控制作用,并通过比较正反控制器的控制性能指标来确定最终采用的控制作用。通过pH值控制的仿真实验证明其对非线性不对称系统的控制效果明显优于传统的在正反方向分别采用PID控制的控制效果。

关键词：非线性不对称系统预测控制控制性能指标 pH值控制

Application of plant extracts cosmetics in the field of anti-aging

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Journal of dermatologic science and cosmetic technology

Journal of dermatologic science and cosmetic technology 2024年第2期1卷 53-62页

作者： minghui Xie Zibing Jiang Xingyue Lin Xingchuan wei School of Chemistry and Chemical Engineering Guangzhou UniversityGuangzhou 510006China

Skin aging is a direct manifestation of body aging,representing a complex and irreversible natural process,which is influenced by genetics,lifestyle and environmental *** the process of skin aging,the skin epidermis gradually become thinner,the inherent repair ability gradually weakens,the collagen and elastin gradually decrease and the skin gradually loses *** skin aging is inevitable,it can be delayed to some extent by using *** extract cosmetics are highly favored by consumers for their safety and efficacy,aligning with consumer preferences for natural,organic,efficient and sustainable skincare *** plant resources in nature possess superior properties like moisturizing,barrier repair,anti-oxidation,sunscreen whitening and anti-inflammatory properties after thousands of years of natural *** properties enable plant components to effectively enhance the anti-aging effects of skincare products through multiple anti-aging pathways,which can be widely used to develop natural anti-aging skin care products.

关键词： Plant resources Anti-aging Green Efficacy skin care Cosmetics

Review on thermal-related measurement methods for superconducting devices and prospect for high-speed maglev transportation application

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Superconductivity 2022年第3期3卷 83-96页

作者： Jun Zheng minghui wei Siyi Quan Yicheng Feng Peng Wen State Key Laboratory of Traction Power Southwest Jiaotong UniversityChengdu 610031People’s Republic of China

High‐temperature superconducting(HTS)bulks can not only be self‐stable when levitated above a permanent magnet(PM)but also can be used as quasi PM with higher magnetic energy product due to their magnetic flux pinning ***,HTS bulks have wide application potentials in maglev trains,maglev bearings,flywheel energy storage,drug delivery,and high field *** the external magnetic field of common application scenarios,HTS bulks have no external input current,so it is difficult to achieve the overall ***,local quenching in the bulk is still possible in the harsh fluctuating external field *** it is difficult to reach the total quench,its critical parameters like Jc will inevitably deteriorate,which may collapse the application ***,in contrast to superconducting wires and tapes that are more concerned with quench detection,HTS bulks with a 3D volume effect are more focused on internal sensitive temperature locations,the impacts of volume and scale,and the coupling influence on application parameters such as magnetism and ***,for efficient thermal‐related measurement of HTS bulk applications,this paper investigates and discusses 12 commonly‐used temperature measurement or quench detection methods in all superconducting application *** methods primarily refer to the current quench detection technologies used in HTS tapes and *** the standpoint of practical temperature measurement requirements of HTS bulks and technological limitations of maglev application scenarios,working characteristics and service conditions of the 12 methods,and 4 temperature detection methods are selected through a comprehensive understanding and comparison of basic *** are expected to be used in real‐time monitoring and early warning schemes for onboard superconducting levitation devices of HTS maglev transportation or other applications in the future.

关键词： High‐temperature superconducting bulk Temperature sensitivity High‐temperature superconducting magnetic levitation High‐temperature superconducting tape Quench detection Temperature detection

碎屑锆石U-Pb年龄谱系对兴安地块落马湖群原岩形成时代的约束

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地球科学 2020年第2期45卷 489-502页

作者：赵院冬车继英许逢明魏明辉中国地质调查局沈阳地质调查中心辽宁沈阳110034

发育于大兴安岭地区如兴华渡口群、落马湖群等系列变质岩系一直被认为是中亚造山带东段各地块的变质基底,但其形成时代目前存在较大争议,制约对于区域大地构造演化的研究.为了查明兴安地块东北部落马湖群原岩形成时代,选取不同层位二云... 详细信息

发育于大兴安岭地区如兴华渡口群、落马湖群等系列变质岩系一直被认为是中亚造山带东段各地块的变质基底,但其形成时代目前存在较大争议,制约对于区域大地构造演化的研究.为了查明兴安地块东北部落马湖群原岩形成时代,选取不同层位二云母片岩开展碎屑锆石LA-ICP-MS U-Pb年龄谱系研究,分析原岩蚀源区特征和最大沉积上限.分析结果表明,两件样品碎屑锆石均为岩浆成因锆石,获得一致的锆石U-Pb年龄谱系,主要集中在400~430 Ma、430~465 Ma、470~520Ma、630~715 Ma、750~830 Ma、880~940 Ma、1720~1870 Ma等7个区间.结合区域地质组成,碎屑锆石年龄谱特征反映原岩蚀源区比较复杂,时空范围较大,但以近源的早古生代岩浆岩为主,而来自额尔古纳地块元古代的岩浆岩和变质岩系可能是重要的物源.根据碎屑锆石最小年龄(406~411 Ma),确定原岩沉积时代的上限为早泥盆世早期,而不是原认为的形成于新元古代-早寒武世.结合原岩沉积建造对比,推断落马湖群可能与上志留统-下泥盆统系列地层(如卧都河组、泥鳅河组)为同时代同环境沉积建造,现有差异可能源于后期经受不同的变质作用.其变形变质作用可能发生在中生代,与蒙古鄂霍茨克洋的闭合作用相关.

关键词：兴安地块落马湖群碎屑锆石形成时代地球化学