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Theta Oscillations support Prefrontal-hippocampal Interactions in Sequential Working Memory

Neuroscience Bulletin 2024年第2期40卷 147-156页

作者： minghong su Kejia Hu Wei Liu Yunhao Wu Tao Wang Chunyan Cao Bomin sun Shikun Zhan Zheng Ye Institute of Psychology Chinese Academy of SciencesBeijing 100101China Department of Psychology University of Chinese Academy of SciencesBeijing 100049China Department of Neurosurgery Center for Functional NeurosurgeryRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Institute of Neuroscience Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai 200031China

The prefrontal cortex and hippocampus may support sequential working memory beyond episodic memory and spatial navigation.This stereoelectroencephalography(SEEG)study investigated how the dorsolateral prefrontal cortex(DLPFC)interacts with the hippocampus in the online processing of sequential information.Twenty patients with epilepsy(eight women,age 27.6±8.2 years)completed a line ordering task with SEEG recordings over the DLPFC and the hippocampus.Participants showed longer thinking times and more recall errors when asked to arrange random lines clockwise(random trials)than to maintain ordered lines(ordered trials)before recalling the orientation of a particular line.First,the ordering-related increase in thinking time and recall error was associated with a transient theta power increase in the hippocampus and a sustained theta power increase in the DLPFC(3–10 Hz).In particular,the hippocampal theta power increase correlated with the memory precision of line orientation.Second,theta phase coherences between the DLPFC and hippocampus were enhanced for ordering,especially for more precisely memorized lines.Third,the theta band DLPFC→hippocampus influence was selectively enhanced for ordering,especially for more precisely memorized lines.This study suggests that theta oscillations may support DLPFC-hippocampal interactions in the online processing of sequential information.

关键词： Sequential working memory Hippocampus Dorsolateral prefrontal cortex Theta oscillations Stereoelectroencephalography(SEEG) Phase coherence Granger causality

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Increased N6-methyladenosine is related to the promotion of the methyltransferase METTL14 in ovarian aging

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Genes & Diseases 2024年第3期11卷 151-154页

作者： Chunfeng Qian Zhenxing Liu Yonghong Qian Jie Ding Rulei Chen Han su minghong Shen Hong Li Boxian Huang State Key Laboratory of Reproductive Medicine and Offspring Health Suzhou Affliated Hospital of Nanjing Medicine and Offspring HealthSuzhou Affiliated Hospital of Nanjing Medical UniversitySuzhouMunicipal HospitalGusu SchoolNanjing Medical UniversitySuzhouJiangsu 215002China Department of Gynecology Affliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu School of Nanjing Medical UniversitySuzhouJiangsu 215002China Department of Pathology Affiliated Suzhou Hospital of Nanjing Medical UniversitySuzhou Municipal HospitalGusu School of Nanjing Medical UniversitySuzhouJiangsu 215002China

The ovary is a vital female reproductive organ that functions to produce oocyte gametes and cyclically expressed sex hormones to maintain reproductive capacity and hormone homeostasis.Ovarian aging,characterized by declines in follicle quantity and oocyte quality,leads to premature ovarian failure,premature ovarian insufficiency,or diminished ovarian reserve,thus contributing to female infertility.Distinct gene-expression signatures from RNA transcriptional level and post-transcriptional regulation are relative to oocyte quality and reproductive age.

关键词： promotion signature maintain

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Mechanistic roles of the subthalamic nucleus and internal globus pallidus:evidence from local field potentials and deep brain stimulation

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Journal of Translational Neuroscience 2018年第4期3卷 1-14页

作者： minghong su Zheng Ye Institute of Psychology Chinese Academy of Sciences Beijing 100101 China Department of Psychology University of Chinese Academy of Sciences Beijing 100049 China Institute of Neuroscience Key Laboratory Primate Neurobiology CAS Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences Shanghai 200031 China

Deep brain stimulation (DBS) has become an effective therapeutic option for neurological and psychiatric disorders such as Parkinson’s disease (PD), dystonia, and obsessive-compulsive disorder. The subthalamic nucleus (STN) and internal globus pallidus (GPi) are by far the most commonly used targets for DBS in the treatment of PD. However, STN/GPi stimulation sometimes causes side effects, including motor fluctuations, cognitive declines, and worse emotional experience, which affect patients’ postoperative quality of life. Recent invasive electrophysiological studies are driven by the desire to better understand the mechanisms of therapeutic actions and side effects of STN/GPi stimulation. These studies investigated the function of the STN and GPi in motor, cognitive and affective processes by recording single- neuron firing patterns during the surgery or local field potentials after the surgery. Here we review the relevant studies to provide an integrative picture of the functional roles of the STN and GPi within the basal ganglia loops for motor, cognition, and emotion. Previous studies suggested that STN and GPi gamma oscillations encode the strength and speed of voluntary movements (execution), whereas beta oscillations reflect the effort and demand of potential movements (preparation). In the cognitive domain, oscillatory beta activity in the STN is involved when people have to stop an inappropriate action or to suppress salient but task-irrelevant information, whereas theta/delta activity is associated with the adjustment of decision thresholds and cost-benefit trade-off. In the affective domain, STN activity in the alpha band may represent the valence and arousal of emotional information.

关键词： subthalamic nucleus (STN) internal globus pallidus (GPi) prefrontal cortex neuronal oscillations local field potentials (LFP) deep brain stimulation (DBS)

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基于改进模型预测的并网变换器自适应虚拟惯性控制策略研究

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电力系统保护与控制 2024年第13期52卷 35-46页

作者：郑峰苏明鸿陈静刘宝谨刘莞玲梁宁福州大学电气工程与自动化学院福建福州350108 国网兰州供电公司甘肃兰州730070 福州大学计算机与大数据学院福建福州350108 昆明理工大学电力工程学院云南昆明650500

针对低惯性直流微电网中母线电压易受网内功率波动影响的问题,提出了一种基于改进模型预测的直流微电网并网变换器自适应虚拟惯性控制策略。首先,电压外环引入自适应类虚拟同步发电机控制,通过将控制方程中的虚拟惯性参数与电压变化率... 详细信息

针对低惯性直流微电网中母线电压易受网内功率波动影响的问题,提出了一种基于改进模型预测的直流微电网并网变换器自适应虚拟惯性控制策略。首先,电压外环引入自适应类虚拟同步发电机控制,通过将控制方程中的虚拟惯性参数与电压变化率结合起来,实现虚拟惯性参数的灵活可调。其次,在电流内环引入模型预测控制,并采用改进延时补偿算法,实现对给定电流值快速跟踪的同时改善控制系统的动态特性。最后,基于Matlab/Simulink建立了系统模型进行仿真。结果表明,与传统的虚拟惯性控制策略相比较,所提控制策略下的直流母线电压波动幅值更小且动态性能更佳,可以有效提高直流母线电压的稳定性和直流微电网的惯性。

关键词：直流微电网并网变换器自适应虚拟惯性控制模型预测控制

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贵州务—正—道地区铝土矿含铝岩系中稀土元素富集规律及赋存形式

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矿物学报 2024年第1期44卷 84-96页

作者：苏永虎杜蔺金中国衮民汕郑明泓曾道国向明坤薛洪富巩鑫贵州大学资源与环境工程学院贵州贵阳550025 贵州省有色金属和核工业地质勘查局地质矿产勘查院贵州贵阳550005 贵州省有色金属和核工业地质勘查局地质资料信息中心贵州贵阳550005 贵州省有色金属和核工业地质勘查局贵州贵阳550005

务川-正安-道真(务-正-道)地区是贵州省重要的铝土矿集区,提交铝土矿石资源储量超过7亿吨。区内铝土矿含铝岩系为下二叠统大竹园组,其中广泛富集稀土元素,由于这类稀土元素富集规律和赋存形式尚存在较大争议,综合利用和地质勘探依然缺... 详细信息

务川-正安-道真(务-正-道)地区是贵州省重要的铝土矿集区,提交铝土矿石资源储量超过7亿吨。区内铝土矿含铝岩系为下二叠统大竹园组,其中广泛富集稀土元素,由于这类稀土元素富集规律和赋存形式尚存在较大争议,综合利用和地质勘探依然缺少实际理论依据。本文通过对该区铝土矿含铝岩系的地质特征及其中伴生稀土元素研究,以总结分析稀土元素地球化学特征和富集规律,并讨论其赋存形式。研究结果表明,务-正-道地区含铝岩系中稀土元素基本呈右倾的配分模式,LREE表现为明显富集,Eu负异常明显。该套含铝岩系中上部样品普遍具有Ce正异常,而底部绿泥石泥岩则为Ce负异常。总体而言,稀土元素在研究区北西部和南东部向斜中的含量相对较高,而在中部向斜含铝岩系中相对较低。稀土元素主要赋存在底部的绿泥石泥岩中。其赋存形式可能主要以离子吸附或类质同象置换的形式赋存于铝矿物和黏土矿物表面或晶格中,也存在稀土元素的独立矿物。本研究为该类资源地质勘探和综合利用提供地质地球化学依据。

关键词：稀土元素富集规律赋存形式铝土矿含铝岩系务-正-道地区

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热扩散系统中非厄米趋肤效应的观测

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Science Bulletin 2024年第9期69卷 1228-1236页

作者：刘云开曹培超祁铭鸿黄强开来高峰彭玉桂李鹰祝雪丰 School of Physics and Innovation Institute Huazhong University of Science and TechnologyWuhan 430074China State Key Laboratory of Extreme Photonics and Instrumentation ZJU-Hangzhou Global Scientiﬁc and Technological Innovation CenterZhejiang UniversityHangzhou 310027China International Joint Innovation Center The Electromagnetics Academy at Zhejiang UniversityZhejiang UniversityHaining 314400China Key Lab.of Advanced Micro/Nano Electronic Devices&Smart Systems of Zhejiang Jinhua Institute of Zhejiang UniversityZhejiang UniversityJinhua 321099China Shaoxing Institute of Zhejiang University Zhejiang UniversityShaoxing 312000China

The paradigm shift of Hermitian systems into the non-Hermitian regime profoundly modifies inherent property of the topological systems, leading to various unprecedented effects such as the nonHermitian skin effect(NHSE). In the past decade, the NHSE has been demonstrated in quantum, optical and acoustic systems. Beside those wave systems, the NHSE in diffusive systems has not yet been observed, despite recent abundant advances in the study of topological thermal diffusion. In this work,we design a thermal diffusion lattice based on a modified su-Schrieffer-Heeger model and demonstrate the diffusive NHSE. In the proposed model, the asymmetric temperature field coupling inside each unit cell can be judiciously realized by appropriate configurations of structural parameters. We find that the temperature fields trend to concentrate toward the target boundary which is robust against initial excitation conditions. We thus experimentally demonstrated the NHSE in thermal diffusion and verified its robustness against various defects. Our work provides a platform for exploration of non-Hermitian physics in the diffusive systems, which has important applications in efficient heat collection, highly sensitive thermal sensing and others.

关键词： Non-Hermitian skin effect Asymmetric coupling Thermal metamaterial Heat diffusion

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牡丹籽油的抗敏舒缓和晒后修复功效

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香料香精化妆品 2024年第3期 81-85页

作者：憨菲菲吴震生张晴李明红陶福占苏宁尧舜牡丹生物科技有限公司山东菏泽274000 菏泽牡丹产业技术研究院山东菏泽274000 中国检验检疫科学研究院北京100176

牡丹籽油含有大量不饱和脂肪酸,其理化特性符合化妆品基础油的特殊要求,在化妆品领域具有广阔的发展前景。通过细胞生物学技术、分子生物学技术、生化分析等手段,对牡丹籽油的抗敏舒缓、晒后修复功效及作用机理进行研究。结果表明,牡丹... 详细信息

牡丹籽油含有大量不饱和脂肪酸,其理化特性符合化妆品基础油的特殊要求,在化妆品领域具有广阔的发展前景。通过细胞生物学技术、分子生物学技术、生化分析等手段,对牡丹籽油的抗敏舒缓、晒后修复功效及作用机理进行研究。结果表明,牡丹籽油对辣椒素诱导的人表皮细胞TRPV1的表达、肥大细胞脱颗粒现象均具有抑制作用;对UVB损伤的人表皮细胞、人真皮细胞也具有保护作用。因此将牡丹籽油作为一种具有抗敏舒缓和晒后修复功效的活性原料,在皮肤护理领域具有较高的应用价值。

关键词：牡丹籽油化妆品抗敏舒缓晒后修复

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Isolation and identification of the three rice monotelosomics

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Chinese Science Bulletin 2005年第19期50卷 2182-2186页

作者： YU Hengxiu GONG Zhiyun su Yan GU minghong Department of Agronomy Agricultural College Yangzhou UniversityYangzhou 225009 China

In order to obtain rice monotelosomic, the progeny of 24 telotrisomics, derived from an indica rice vari-ety, Zhongxian 3037, were screened. The variants that dif-fered morphologically from the diploids and the original primary trisomics as well as the telotrisomics were collected for cytological identification. The variants with 24 chromo-somes were selected according to the prometaphase chromo-somes. From these variants, three monotelosomics with one chromosome arm deletion in each were verified by fluores-cence in situ hybridization (FISH) using a rice centromeric BAC clone of 17p22 as a marker probe. The three monote-losomics were derived from telotrisomic 1S, 4L and 11L, re-spectively. Further identification was conducted on the pro-metaphase or pachytene chromosomes of the three variants, which were probed with the same centromeric BAC clone together with the corresponding chromosome arm specific makers, a0059H02 (on the short arm of chromosome 1), a0034E24 (on the long arm of chromosome 4), and a0071H11 (on the long arm of chromosome 11). The results indicated that the telocentric chromosomes in the three monotelosom-ics were derived from their respective corresponding telotrisomics. According to the telocentric chromosomes of the variants, they were monotelosomic 1S (one long arm of chromosome 1 was lost), monotelosomic 4L (one short arm of chromosome 4 was lost) and monotelosomic 11L (one short arm of chromosome 11 was lost), respectively.

关键词：水稻种植技术分子生物学杂交技术染色体

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杨桃种质果实品质性状遗传多样性分析

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食品科学 2020年第17期41卷 68-74页

作者：马小卫苏穆清李栋梁郑斌邹明宏中国热带农业科学院南亚热带作物研究所海南省热带作物营养重点实验室广东湛江524091 岭南师范学院生命科学与技术学院广东湛江524048

以保存于中国热带果树种质资源圃的21份杨桃种质为材料,利用方差分析、相关性分析和主成分分析法对果实形态和糖、酸、矿质营养含量等25项品质性状进行了遗传多样性评价。结果表明:21份杨桃种质果实品质性状存在明显差异,具有丰富多样性... 详细信息

以保存于中国热带果树种质资源圃的21份杨桃种质为材料,利用方差分析、相关性分析和主成分分析法对果实形态和糖、酸、矿质营养含量等25项品质性状进行了遗传多样性评价。结果表明:21份杨桃种质果实品质性状存在明显差异,具有丰富多样性;酒石酸含量变异系数最大(109.95%)、其次为铁含量(104.78%)、柠檬酸含量(79.07%)和总酸含量(73.54%),而果实纵径和可溶性固形物含量的变异系数最小,分别为9.97%和7.44%;一些果实品质性状间存在着显著的相关性;主成分分析结果显示前6个主成分累积方差贡献率为81.63%,各性状的贡献率分散,性状变异具有多向性。

关键词：杨桃种质资源果实品质聚类分析主成分分析

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大众迈腾B7起动系统故障案例分析

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汽车电器 2023年第11期 102-104页

作者：苏明洪张雪文吴建名吴超益阳职业技术学院汽车工程学院湖南益阳413049

文章以一汽大众迈腾B7起动系统故障为例,通过查阅技术资料、原厂维修手册及系统电路图,总结迈腾B7起动系统的控制逻辑并整理出电路图,对起动机的控制可以一目了然。通过系统组成及工作原理,结合电路图分析可能原因,制定诊断方案并进行... 详细信息

文章以一汽大众迈腾B7起动系统故障为例,通过查阅技术资料、原厂维修手册及系统电路图,总结迈腾B7起动系统的控制逻辑并整理出电路图,对起动机的控制可以一目了然。通过系统组成及工作原理,结合电路图分析可能原因,制定诊断方案并进行故障诊断排除,可为汽车维修从业人员提供参考和借鉴。

关键词：起动系统故障诊断迈腾B7

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