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BASIC CHARACTERISTICS OF OIL-GAS POOLS OF ARENACEOUS CONGLOMETRATIC ROCKS IN SHA3-SHA4 MEMBER OF SHAHEJIE FORmaTION IN YAN182-YONG921 REGION OF DONGYING DEPRESSION

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Scientia Geologica Sinica 1999年第4期 485-488页

作者： ma mingfu, Zhangyu, Xu HuaiMing and Shi WenDong(University of petroleum, Dongying, China 257062)

By analyzing the arenaceous conglomeratic rock reservoirs in S3-S4 member of Shahejie Group inDongYing sag, we have studied the lithology, structure, reservoir and so on in the Yan182-Yong921region. Research indicatest the arenaceous conglomeratic rocks of alluvial fan, fan delta and coastalsubaqueous fan can be found in the studied region. Oil pools have three types: lithologic pinchout oil (gas)pools, lithologic pools with small anticline and complex lithologic pools, among which, lithologic poolsare the major advantageous pools that can be developed profitably.

关键词： GAS SHA BASIC CHARACTERISTICS OF OIL-GAS POOLS OF ARENACEOUS CONGLOMETRATIC ROCKS IN SHA3-SHA4 MEMBER OF SHAHEJIE FORmaTION IN YAN182-YO

CHARACTERISTICS AND DISTRIBUTION OF SEALS IN WEST SAG OF TANHAI AREA, LIAOHEBASIN, NORTHEAST CNINA

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Scientia Geologica Sinica 2000年第4期 475-479页

作者： Fang Shihu, Xu Huaimin and ma mingfu (Department of Petroleum Resource Science, University of petroleum, Dongying, Shandong Province 257062)

In this paper we take the Eogene in the west sag of the Tanhai area as the subject of study. Through choosing the parameters and establishing the criteria for seal evaluation, we distinguish the seals that developed in the Eogene formation, accomplish the evaluating of seal grade and quality, nd reveal the relationship between the distribution of hydrocarbon and the distribution of regional seals.

关键词： SAG rock CHARACTERISTICS AND DISTRIBUTION OF SEALS IN WEST SAG OF TANHAI AREA LIAOHEBASIN NORTHEAST CNINA

HETEROGENEITY OF SLUMP-TURBIDITIC FANSANDSTONE RESERVOIRS IN THE DONGYING DEPRESSION

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Scientia Geologica Sinica 1999年第2期 201-205页

作者： ma mingfu and Dai Qide(Department of Petroleum Resource Science and Environmental Geology University of Petroleum,Dongying. Shandong Province 257062)

This paper reveals microscopic and macroscopic heterogeneity of the delta-front slump turbiditic sandstones in Dongying depression. Microscopic heterogeneity chiefly refers to their pores and throats as well as combin... 详细信息

关键词： HETEROGENEITY OF SLUMP-TURBIDITIC FANSANDSTONE RESERVOIRS IN THE DONGYING DEPRESSION

Study on Differential Expression Profile of sperm miRNA between HIV/AIDS patients and Healthy Indivisuals

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Study on Differential Expression Profile of sperm miRNA betw...

第十四次全国医学遗传学学术会议

作者： Lianbing LI Jihua HUANG Yijiang ZHU mingfu ma Qingdong XIE Danyan ZHANG Zhiwei HOU Dian WANG Tianhua HUANG Chongqing Key Laboratory of Birth Defects and Reproductive Health Research Center for Reproductive Medicine Shantou University Medical College Shantou

AIM AND BACKGROUND:The aim of this study was to construct the differential expression profile of sperm miRNA between HIV/AIDS patients and healthy *** AND METHODS:The semen samples were obtained from 34 patients infected with HIV/AIDS and 20 age-matched *** RNA were extracted to construct the differential expression profile of miRNA by using gene chip technology and identified by using real-time fluorescent quantitative PCR(qPCR).The differential expression significant miRNAs were selected and compared with both viral and human miRNAs in miRBase database to determine their ***:High mobility and low mobility sperm were successfully separated without somatic cell *** results of miRNA differential expression profile data analysis showed that there were77 miRNAs which were up-regulated and hiv1-miR-H1,with a fold 51.262568 difference in expression,was the most different,while there were 81 miRNAs which were downregulated,and has-miR-1299,with a fold 0.006907 difference in expression was the most *** candidate miRNAs were selected for verification based on thefinding of up or down regulation in the spermatozoa of HIV patients:hsa-miR-155-5p and hsa-miR-107 were increased in HIV patients,and hsa-miR-1299,has-miR-513a-3p,has-miR-148a-3p,has-miR-221-5p were decreased,which were consonant with the result of gene chip ***:

关键词： miRNA sperm AIDS

Association between polymorphisms in IL27 and risk for CHD in a Chinese population

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Association between polymorphisms in IL27 and risk for CHD i...

第十四次全国医学遗传学学术会议

作者： Danyan Zhang mingfu ma Yuyou Yang Ling Wan Zhixi Yang Jing Lv Xinsheng Li Hao Yang Pei Huang Lianbing Li Key Laboratory of Birth Defects and Reproductive Health of National Health and Family Planning Commission Chongqing Population and Family Planning Science and Technology Research Institute Chongqing Zheng-ding Judicial Identification Institute The Third Military Medical University

Background:IL—27,a member of the IL-12 family,has been involved in maternal tolerance to the fetus and successful *** evidences indicate that IL-27 plays a crucial role in ***:We carried out the present study in order to investigate whether polymorphisms in the IL27 are associated with the risk for CHDs,including atrial septal defect and ventricular septal ***:We conducted this case-control study among 247 atrial septal defect patients,150 ventricular septal defect patients,and 368 healthy controls in a Chinese population using polymerase chain reaction-restriction fragment length polymorphism ***:Significantly increased risk for atrial septal defect(p=0.001,OR=1.490,95%Cl=1.178-1.887)and ventricular septal defect(p=0.004,OR=1.502,95%Cl=1.139-1.976)was observed to be associated with the allele G of *** a dominant model,we have also observed that increased susceptibilities for atrial septal defect(pmay be associated with the susceptibility to CHD,including atrial septal defect and ventricular septal defect.

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阿尔及利亚D区块储层特征及影响因素分析

西南石油大学学报（自然科学版） 2012年第5期34卷 25-30页

作者：马明福贾赢张春书中国石油天然气勘探开发公司北京西城100034

下泥盆Siegenian组砂岩储层是阿尔及利亚D区块的主要勘探目的层。研究其储层特征及控制因素对勘探潜力的评价及后期开发有着重要的指导意义。经过研究,块内砂岩类型主要为石英砂岩,岩屑石英砂岩,储层储集空间主要为各种类型的次生孔隙... 详细信息

下泥盆Siegenian组砂岩储层是阿尔及利亚D区块的主要勘探目的层。研究其储层特征及控制因素对勘探潜力的评价及后期开发有着重要的指导意义。经过研究,块内砂岩类型主要为石英砂岩,岩屑石英砂岩,储层储集空间主要为各种类型的次生孔隙和少量的裂缝,原生粒间孔不发育,多为粒间溶孔、粒内溶孔及微裂隙。孔隙结构主要为中小孔微细喉,储层物性较差,为中低孔、特低渗储层类储层;储层性质主要受到沉积条件和成岩作用的控制,成岩作用中以压实作用和溶蚀作用对储层物性影响最大,其次是胶结作用和交代作用。

关键词：阿尔及利亚沉积特征孔隙结构影响因素成岩作用

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Research on the Vertical Transmission of Hepatitis C Gene from Father-to-child via Human Sperm

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第十四次全国医学遗传学学术会议

作者： mingfu ma Yijian Zhu Dian Wang Zhiwei Hou Jihua Huang Danyan Zhang Qingdong Xie Ling Wan Letian Zhao Li Wei Lianbing Li Tianhua Huang Key Laboratory of Birth Defects and Reproductive Health of National Health and Family Planning Commission(Chongqing Population and family planning Science and Technology Research Institute) Research Center for Reproductive Medicine Shantou University Medical College

Background:The aim was to determine the degree of chromosomal aberrations in the sperm of men with hepatitis C,develop a better experimental model which could facilitate further studies assessing the vertical HCV gene transmission via human spermatozoa,and verify the possibility of father-to-child transmission of the HCV ***:36 subjects(20 as healthy control group and 16 as HCV infection group[genotype1b])were *** samples from the subjects were used for interspecies in vitro fertilization of zona-free golden hamster *** frequencies of spermatozoan aberrations were compared between the healthy control group and the HCV infection *** recombinant plasmid plRES2-EGFP-HCV C was *** in situ hybridization was performed to detect the integration of the HCV C gene in human sperm genome and in zygote’s ***:A total of 280 sperm chromosome complements were studied,including 129 complements from the 16 donors in the HCV infection group and 151 from the healthy control *** the 129 analyzable sperm metaphase spreads in the HCV infection group,14(10.85%)complements contained chromosomal aberrations,which was significantly higher than the number(9/151,5.96%)in the healthy control group(Pman sperm chromosomes and two-cell embryos in transfected *** positive signal was found in normal control and HCV infected ***:HCV infection has mutagenic effects on the chromosomes in sperm,and may lead to extensive hereditary effects owing to genetic alterations and/or chromosomal *** HCV C gene was able to pass through sperm membrane and integrate into the sperm *** sperm carrying the HCV C gene was able to achieve normal *** replication of the sperm-mediated HCV C gene was synchronized with that of the host *** results provide direct evidence for vertical transmission of the HCV C gene from father-t

关键词： fluorescent in situ hybridization(FISH) Hepatitis C Sperm chromosome Spermatozoa Viral transmission

Effects of hepatitis C virus infection on human sperm chromosomes

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Effects of hepatitis C virus infection on human sperm chromo...

第十四次全国医学遗传学学术会议

作者： Yijian Zhu mingfu ma Jihua Huang Zhiwei Hou Dian Wang Danyan Zhang Qingdong Xie Ling Wan Letian Zhao Li Wei Lianbing Li Tianhua Huang Key Laboratory of Birth Defects and Reproductive Health of National Health and Family Planning Commission(Chongqing Population and family planning Science and Technology Research Institute) Research Center for Reproductive Medicine Shantou University Medical College

Background:To determine the degree of chromosomal aberrations in the sperm of men with hepatitis ***:36 subjects(20 as healthy control group and 16 as HCV infection group[genotype 1b])were *** cause of viral transmission was unknown in all *** samples from the subjects were used for interspecies in vitro fertilization of zona-free golden hamster *** frequencies of spermatozoan aberrations were compared between the healthy control group and the HCV infection ***:A total of 280 sperm chromosome complements were studied,including129 complements from the 16 donors in the HCV infection group and 151 from the healthy control *** the 129 analyzable sperm metaphase spreads in the HCV infection group,14(10.85%)complements contained chromosomal aberrations,which was significantly higher than the number(9/151,5.96%)in the healthy control group(Pmalies such as stickiness,clumping,and failure to stain,which prevented their ***:HCV infection has mutagenic effects on the chromosomes in sperm,andmay lead to extensive hereditary effects owing to genetic alterations and/or chromosomal *** addition,there is the possibility of vertical transmission of HCV via the germ line.

关键词： Hepatitis C Sperm chromosome Chromosomal aberration male

侵袭性B细胞淋巴瘤中PIK3CA扩增和PTEN缺失及其临床病理学意义

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中国肿瘤临床 2018年第8期45卷 379-384页

作者：马明福余丽马志萍张巍崔文丽新疆医科大学第一附属医院病理科乌鲁木齐市830000 新疆医科大学第一附属医院昌吉分院病理科

目的:探讨侵袭性B细胞淋巴瘤在PI3K/Akt/mTOR信号通路中PIK3CA与10号染色体上缺失的磷酸酶和张力蛋白同源物(phosphate and tension homology deleted on chromsome ten,PTEN)的表达情况及其与各临床病理指标的相关性。方法:回顾性分析... 详细信息

目的:探讨侵袭性B细胞淋巴瘤在PI3K/Akt/mTOR信号通路中PIK3CA与10号染色体上缺失的磷酸酶和张力蛋白同源物(phosphate and tension homology deleted on chromsome ten,PTEN)的表达情况及其与各临床病理指标的相关性。方法:回顾性分析新疆医科大学第一附属医院2008年1月至2012年12月术前未经任何治疗的侵袭性B细胞淋巴瘤标本235例,其中包括弥漫大B细胞淋巴瘤(diffuse large B-cell lymphoma,DLBCL)205例,伯基特淋巴瘤(Burkitt lymphoma,BL)27例,灰区淋巴瘤(介于DLBCL和BL之间,不能分类的B细胞淋巴瘤)3例。应用荧光原位杂交技术检测所有样本PIK3CA和PTEN基因的表达情况,统计分析其与各临床病理指标及预后的关系。结果:PIK3CA在侵袭性B细胞淋巴瘤中扩增率为12.3%(29/235),临床分期Ⅰ~Ⅱ期和Ⅲ~Ⅳ期的阳性率分别为8.6%(12/139)和17.7%(17/96),差异具有统计学意义(P=0.038)。PTEN在侵袭性B细胞淋巴瘤中的缺失率为13.6%(32/235),与其他临床病理特征无相关性。PIK3CA扩增和PTEN缺失呈负相关(P=0.046)。未发现PIK3CA扩增和PTEN缺失与生存期存在相关性。结论:PIK3CA扩增与侵袭性B细胞淋巴瘤疾病晚期相关,PIK3CA扩增和PTEN缺失在侵袭性B细胞淋巴瘤的发生中起促进作用。

关键词：侵袭性B细胞淋巴瘤 PIK3CA PTEN 临床病理学特征

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